Cited by 589Body Composition Measurement TechniquesNutrition and Health StudiesRegulation of Appetite and Obesity

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index; none of the 28 sources its claims cite is checked for support yet.

Daily energy expenditure through the human life course

Open access
Pontzer, Herman, Yamada, Yosuke, Sagayama, Hiroyuki, Ainslie, Philip N., Andersen, Lene F., Anderson, Liam J., Arab, Lenore, Baddou, Issaad, Bedu-Addo, Kweku, Blaak, Ellen E., Blanc, Stephane, Bonomi, Alberto G., Bouten, Carlijn V. C., Bovet, Pascal, Buchowski, Maciej S., Butte, Nancy F., Camps, Stefan G., Close, Graeme L., Cooper, Jamie A., Cooper, Richard, Das, Sai Krupa, Dugas, Lara R., Ekelund, Ulf, Entringer, Sonja, Forrester, Terrence, Fudge, Barry W., Goris, Annelies H, Gurven, Michael, Hambly, Catherine, El Hamdouchi, Asmaa, Hoos, Marjije B., Hu, Sumei, Joonas, Noorjehan, Joosen, Annemiek M., Katzmarzyk, Peter, Kempen, Kitty P., Kimura, Misaka, Kraus, William E., Kushner, Robert F., Lambert, Estelle V., Leonard, William R., Lessan, Nader, Martin, Corby, Medin, Anine C., Meijer, Erwin P., Morehen, James C., Morton, James P., Neuhouser, Marian L., Nicklas, Teresa A., Ojiambo, Robert M., Pietiläinen, Kirsi H., Pitsiladis, Yannis P., Plange-Rhule, Jacob, Plasqui, Guy, Prentice, Ross L., Rabinovich, Roberto A., Racette, Susan B., Raichlen, David A., Ravussin, Eric, Reynolds, Rebecca M., Roberts, Susan B., Schuit, Albertine J., Sjödin, Anders M., Stice, Eric, Urlacher, Samuel S., Valenti, Giulio, Van Etten, Ludo M., Van Mil, Edgar A., Wells, Jonathan C. K., Wilson, George, Wood, Brian M., Yanovski, Jack, Yoshida, Tsukasa, Zhang, Xueying, Murphy-Alford, Alexia J., Loechl, Cornelia, Luke, Amy H., Rood, Jennifer, Schoeller, Dale A., Westerterp, Klaas R., Wong, William W., Speakman, John R., IAEA DLW Database Consortium§·2021·Science

Abstract

A lifetime of change: Measurements of total and basal energy in a large cohort of subjects at ages spanning from before birth to old age document distinct changes that occur during a human lifetime. Pontzer et al . report that energy expenditure (adjusted for weight) in neonates was like that of adults but increased substantially in the first year of life (see the Perspective by Rhoads and Anderson). It then gradually declined until young individuals reached adult characteristics, which were maintained from age 20 to 60 years. Older individuals showed reduced energy expenditure. Tissue metabolism thus appears not to be constant but rather to undergo transitions at critical junctures. —LBR

Overview

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Registry

Crossref · 10.1126/science.abe5017

Cites

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Claims the paper makes

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  • It may state two separate claims as one. 17
  • Probably not a substantial claim. 1
17 of 17
  • The authors state this as an assumption.

    Activity costs are proportional to body weight.

    “assuming activity costs are proportional to weight”
  • The authors state this as an assumption.

    Basal expenditure can be modeled as a power function of fat-free mass multiplied by a tissue-specific metabolism term.

    “basal expenditure was modeled as a power function of fat free mass (consistent with organ-based BEE estimates; Methods) multiplied by a “tissue specific metabolism” term”
2 of 2

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  • Neonatal basal expenditure is reported as both 78% and approximately 100% of adult levels

    Minor

    The first-month estimate for adjusted basal expenditure is 78.1% of the adult-expected value, but the later discussion describes both adjusted measures in the first weeks after birth as approximately 100%.

1 of 1

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  1. M. Elia in Physiology Stress and Malnutrition J. M. Kinney H. N. Tucker Eds. (Raven Press 1997) pp. 383–411.

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Metadata

Authors
Pontzer, H., Yamada, Y., Sagayama, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A. G., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F., Camps, S. G., Close, G. L., Cooper, J. A., Cooper, R., Das, S. K., Dugas, L. R., Ekelund, U., Entringer, S., Forrester, T., Fudge, B. W., Goris, A. H., Gurven, M., Hambly, C., El Hamdouchi, A., Hoos, M. B., Hu, S., Joonas, N., Joosen, A. M., Katzmarzyk, P., Kempen, K. P., Kimura, M., Kraus, W. E., Kushner, R. F., Lambert, E. V., Leonard, W. R., Lessan, N., Martin, C., Medin, A. C., Meijer, E. P., Morehen, J. C., Morton, J. P., Neuhouser, M. L., Nicklas, T. A., Ojiambo, R. M., Pietiläinen, K. H., Pitsiladis, Y. P., Plange-Rhule, J., Plasqui, G., Prentice, R. L., Rabinovich, R. A., Racette, S. B., Raichlen, D. A., Ravussin, E., Reynolds, R. M., Roberts, S. B., Schuit, A. J., Sjödin, A. M., Stice, E., Urlacher, S. S., Valenti, G., Van Etten, L. M., Van Mil, E. A., Wells, J. C. K., Wilson, G., Wood, B. M., Yanovski, J., Yoshida, T., Zhang, X., Murphy-Alford, A. J., Loechl, C., Luke, A. H., Rood, J., Schoeller, D. A., Westerterp, K. R., Wong, W. W., Speakman, J. R., & IAEA DLW Database Consortium§
Affiliations
  • Duke University (US)
  • National Institute of Health and Nutrition (JP)
  • University of Tsukuba (JP)
  • Liverpool John Moores University (GB)
  • University of Oslo (NO)
  • University of California, Los Angeles (US)
  • Unité Mixte de Recherche en Nutrition et Alimentation, CNESTEN–Université Ibn Tofail URAC39, Regional Designated Center of Nutrition Associated with AFRA/IAEA, Rabat, Morocco.
  • Kwame Nkrumah University of Science and Technology (GH)
  • Maastricht University (NL)
  • Department of Nutritional Sciences, University of Wisconsin, Madison, WI, USA.
  • Philips (Netherlands) (NL)
  • Centre Hospitalier Universitaire Vaudois (CH)
  • Vanderbilt University (US)
  • Baylor College of Medicine (US)
  • University of Wisconsin–Madison (US)
  • Loyola University Chicago (US)
  • Tufts University (US)
  • Norwegian School of Sport Sciences (NO)
  • University of California, Irvine (US)
  • University of the West Indies System (JM)
  • University of Glasgow (GB)
  • University of California, Santa Barbara (US)
  • University of Aberdeen (GB)
  • Maastricht University, Maastricht, Netherlands.
  • Chinese Academy of Sciences (CN)
  • Central Health Laboratory, Ministry of Health and Wellness, Candos, Mauritius.
  • Pennington Biomedical Research Center (US)
  • Kyoto University of Advanced Science (JP)
  • Northwestern University (US)
  • University of Cape Town (ZA)
  • Imperial College London Diabetes Centre (AE)
  • The Football Association (GB)
  • University of Washington (US)
  • Moi University (KE)
  • Helsinki University Hospital (FI)
  • University of Brighton (GB)
  • Department of Physiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • The Queen's Medical Research Institute (GB)
  • Washington University in St. Louis (US)
  • University of Southern California (US)
  • Pennington Biomedical Research Center, Baton Rouge, LA, USA.
  • Tilburg University (NL)
  • University of Copenhagen (DK)
  • Stanford University (US)
  • Baylor University (US)
  • Maastricht University, Maastricht and Lifestyle Medicine Center for Children, Jeroen Bosch Hospital, Hertogenbosch, Netherlands.
  • University College London (GB)
  • National Institutes of Health (US)
  • Nutritional and Health Related Environmental Studies Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria.
  • International Atomic Energy Agency (AT)
  • Maastricht University Medical Centre (NL)
Corresponding author
  • Pontzer, Herman
  • Yamada, Yosuke
  • Sagayama, Hiroyuki
  • Luke, Amy H.
  • Rood, Jennifer
  • Schoeller, Dale A.
  • Westerterp, Klaas R.
  • Wong, William W.
  • Speakman, John R.
Venue
Science
Published
2021-08-13
Volume
373
Issue
6556
Pages
808-812
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W3183815414
Cited by
583
References
54
Citations by year
2026: 100 · 2025: 127 · 2024: 112 · 2023: 106 · 2022: 116 · 2021: 20
FWCI
56.71
Type
journal article
Language
en
Licence
cc-by
Locations
  • Science (publishedVersion)
  • Research portal (Tilburg University) (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, other-oa)
  • University of Birmingham Research Portal (University of Birmingham) (publishedVersion)
  • TU/e Research Portal (acceptedVersion, other-oa)
  • Liverpool John Moores University (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • Edinburgh Research Explorer (University of Edinburgh) (acceptedVersion, other-oa)
  • University of Brighton Repository (University of Brighton) (submittedVersion, other-oa)
  • Digital Commons-TMC (Texas Medical Center) (submittedVersion)
  • Civil War Book Review (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, cc-by)
  • HAL (submittedVersion, other-oa)
  • Research Publications (Maastricht University) (submittedVersion, other-oa)
  • UCL Discovery (University College London) (submittedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
  • IRIS (submittedVersion)
  • NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
  • SERVAL (Université de Lausanne) (submittedVersion)
  • TU/e Research Portal (submittedVersion, other-oa)
Funders
National Science Foundation (BCS-1824466)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Keywords
daily energy expenditure, life course, fat-free mass, power-law scaling, neonates, pregnancy, aging, human development, doubly labeled water, energy demand
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Aging, Basal Metabolism, Body Composition, Body Weight, Child, Child, Preschool, Energy Metabolism, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Pregnancy, Exercise, Young Adult

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