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Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
Open accessAbstract
Treating neutropenic fever with broad-spectrum antibiotics after allogeneic hematopoietic stem cell transplant is associated with an increase in graft-versus-host disease in mice and humans.
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“Each of these outcomes, as well as overall survival, has been associated in single-center studies with features of the intestinal microbiota in the period after hematopoietic-cell transplantation.2–4,8–15”
From Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation (2020) · cites this paper as [10]
In the citing paper
“and exposure to certain antibiotic agents at specific times is associated with transplantation-related mortality and GVHD-related mortality.10,16”
From Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation (2020) · cites this paper as [10]
In the citing paper
“Preclinical models have shown that commensal bacteria influence the pathophysiology of GVHD.10,17–20”
From Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation (2020) · cites this paper as [10]
In the citing paper
“Conversely, depletion of gut microbes by broad-spectrum antibiotics prior to T cell therapy can reduce ICB efficacy9 or increase GVHD-related mortality10.”
From A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy (2023) · cites this paper as [10]
In the citing paper
“These antibiotics exert a considerable broad-spectrum, anti-pseudomonal activity, and are also known to severely disrupt the gut microbiome by targeting many anaerobic commensals10,26.”
From A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy (2023) · cites this paper as [10]
In the citing paper
“Dysbiosis and impaired systemic immunity is fairly common in these patients, as they are often treated with concurrent therapies that significantly alter immunity and composition of the gut microbiota”
From The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy (2018) · cites this paper as Shono et al., 2016
In the citing paper
“The gut microbiota may also be impacted by antibiotic treatment for infectious complications during HSCT, with differences in GVHD-associated mortality with different antibiotic regimens”
From The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy (2018) · cites this paper as Shono et al., 2016
In the citing paper
“more recent studies demonstrating detrimental effects of antibiotic use with higher rates of GVHD”
From The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy (2018) · cites this paper as Shono et al., 2016
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Cites
Trimmomatic: a flexible trimmer for Illumina sequence data
Bolger, A. M., Lohse, M., & Usadel, B. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu170 · Cited by 65,548
Schloss, P. D., Westcott, S. L., Ryabin, T., Hall, J. R., Hartmann, M., Hollister, E. B., Lesniewski, R. A., Oakley, B. B., Parks, D. H., Robinson, C. J., et al. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.01541-09 · Cited by 21,408
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 20,145
Metagenomic biomarker discovery and explanation
Segata, N., Izard, J., Waldron, L., Gevers, D., Miropolsky, L., Garrett, W. S., & Huttenhower, C. (2011) · Genome Biology · doi:10.1186/gb-2011-12-6-r60 · Cited by 16,192
Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
DeSantis, T. Z., Hugenholtz, P., Larsen, N., Rojas, M., Brodie, E. L., Keller, K., Huber, T., Dalevi, D., Hu, P., & Andersen, G. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.03006-05 · Cited by 10,891
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N., & Garrett, W. S. (2013) · Science · doi:10.1126/science.1241165 · Cited by 5,413
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
Arpaia, N., Campbell, C., Fan, X., Dikiy, S., van der Veeken, J., deRoos, P., Liu, H., Cross, J. R., Pfeffer, K., Coffer, P. J., et al. (2013) · Nature · doi:10.1038/nature12726 · Cited by 4,838
Kraken: ultrafast metagenomic sequence classification using exact alignments
Wood, D. E., & Salzberg, S. L. (2014) · Genome Biology · doi:10.1186/gb-2014-15-3-r46 · Cited by 4,521
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Items 201–300 of 592
Dandoy, C. E., Kelley, T., Gaur, A. H., Nagarajan, R., Demmel, K., Badia, P., Guinipero, T. L., Savelli, S., Hakim, H., Owings, A., et al. (2019) · Pediatric Blood & Cancer · doi:10.1002/pbc.27978 · Cited by 27
Bowerman, K. L., Varelias, A., Lachner, N., Kuns, R. D., Hill, G. R., & Hugenholtz, P. (2020) · Gut Microbes · doi:10.1080/19490976.2019.1705729 · Cited by 26
Clemmons, A. B., Bech, C. F., Pantin, J. M., & Ahmad, I. (2017) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2017.12.799 · Cited by 27
Benoit, S. W., Goldstein, S. L., Dahale, D. S., Haslam, D. B., Nelson, A., Truono, K., & Davies, S. M. (2019) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2019.04.022 · Cited by 27
Camargo, J. F., Anderson, A. D., Natori, Y., Natori, A., Morris, M. I., Pereira, D. L., & Komanduri, K. V. (2020) · Blood Advances · doi:10.1182/bloodadvances.2020003277 · Cited by 26
Dörner, P. J., Anandakumar, H., Röwekamp, I., Vernengo, F. F., Pascual-Leone, B. M., Krzanowski, M., Sellmaier, J., Brüning, U., Fritsche‐Guenther, R., Pfannkuch, L., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47149-z · Cited by 27
Ichinohe, T., Miyama, T., Kawase, T., Honjo, Y., Kitaura, K., Sato, H., Shin‐I, T., & Suzuki, R. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00668 · Cited by 26
Oku, S., Takeshita, T., Futatsuki, T., Kageyama, S., Asakawa, M., Mori, Y., Miyamoto, T., Hata, J., Ninomiya, T., Kashiwazaki, H., et al. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008348 · Cited by 26
Song, Q., Wang, X., Wu, X., Kang, T. H., Qin, H., Zhao, D., Jenq, R. R., van den Brink, M. R. M., Riggs, A. D., Martin, P. J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21133-3 · Cited by 26
Self-citationCamargo, J. F., Mendoza, M. A., Lin, R. Y., Moroz, I. V., Anderson, A. D., Morris, M. I., Natori, Y., Natori, A., Raja, M. A., Lekakis, L. J., et al. (2021) · Transplant Infectious Disease · doi:10.1111/tid.13625 · Cited by 26
Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease
Mohamed, F. A., Thangavelu, G., Rhee, S. Y., Sage, P. T., O’Connor, R. S., Rathmell, J. C., & Blazar, B. R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.757836 · Cited by 26
Applications of gut microbiota in patients with hematopoietic stem-cell transplantation
Yu, J., Sun, H., Cao, W., Han, L., Song, Y., Wan, D., & Jiang, Z. (2020) · Experimental Hematology & Oncology · doi:10.1186/s40164-020-00194-y · Cited by 25
Mucositis and Infection in Hematology Patients
Blijlevens, N. M. A., & de Mooij, C. E. M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24119592 · Cited by 30
Liu, C., Rosen, E. A., Stohs, E. J., Imlay, H. N., Nigo, M., Gottesdiener, L. S., So, M., Tverdek, F. P., Dadwal, S., Gudiol, C., et al. (2025) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(25)00311-1 · Cited by 25
Self-citationZiegler, M. J., Landsburg, D. J., Pegues, D. A., Bilker, W. B., Gilmar, C., Kucharczuk, C., Gorman, T., Bink, K., Moore, A., Fitzpatrick, R., et al. (2018) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2018.11.023 · Cited by 25
Bansal, R., Park, H., Taborda, C., Gordillo, C. A., Mapara, M. Y., Assal, A., Uhlemann, A., & Reshef, R. (2021) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2021.12.015 · Cited by 28
Milestones in acute GVHD pathophysiology
Socié, G., & Michonneau, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1079708 · Cited by 28
Zhong, S., Zeng, J., Deng, Z., Jiang, L., Zhang, B., Yang, K., Wang, W., & Zhang, T. (2019) · The Italian Journal of Pediatrics/Italian journal of pediatrics · doi:10.1186/s13052-019-0708-9 · Cited by 26
Biomarkers for acute and chronic graft versus host disease: state of the art
Giaccone, L., Faraci, D., Butera, S., Lia, G., Vito, C. D., Gabrielli, G., Cerrano, M., Mariotti, J., Dellacasa, C. M., Felicetti, F., et al. (2020) · Expert Review of Hematology · doi:10.1080/17474086.2021.1860001 · Cited by 26
The Microbiota: A New Variable Impacting Cancer Treatment Outcomes
Fessler, J. L., & Gajewski, T. F. (2017) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-0864 · Cited by 24
Elgarten, C. W., Li, Y., Getz, K., Hemmer, M., Huang, Y.-S. V., Hall, M., Wang, T., Kitko, C. L., Jagasia, M., Nishihori, T., et al. (2020) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2020.10.012 · Cited by 25
Figliuolo, V. R., Jamwal, D. R., & Kiela, P. R. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-6407-9_9 · Cited by 28
Holmes, Z. C., Tang, H., Liu, C., Bush, A. T., Neubert, B. C., Jiao, Y., Covington, M. K., Cardona, D. M., Kirtley, M. C., Chen, B. J., et al. (2022) · Blood · doi:10.1182/blood.2021015178 · Cited by 26
Self-citationIshikawa, K., Masaki, T., Kawai, F., Ota, E., & Mori, N. (2023) · Cancers · doi:10.3390/cancers15051611 · Cited by 24
Lind, M. L., Phipps, A. I., Mooney, S. J., Liu, C., Fohner, A. E., Patel, K. B., Ueda, M., & Pergam, S. A. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa214 · Cited by 24
Self-citationThe microbiome in pediatric oncology
Rotz, S. J., & Dandoy, C. E. (2020) · Cancer · doi:10.1002/cncr.33030 · Cited by 22
Optimizing Donor Choice and GVHD Prophylaxis in Allogeneic Hematopoietic Cell Transplantation
Holtan, S. G., Versluis, J., Weisdorf, D. J., & Cornelissen, J. J. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.20.01771 · Cited by 23
Chanderraj, R., Brown, C. A., Hinkle, K. J., Falkowski, N. R., Woods, R. J., & Dickson, R. P. (2022) · Microbiome · doi:10.1186/s40168-021-01190-y · Cited by 23
Margolis, E. B., Marón, G. M., Sun, Y., Dallas, R. H., Allison, K., Ferrolino, J. A. A., Ross, H. S., Davis, A., Jia, Q., Turner, P., et al. (2023) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad190 · Cited by 24
The role of microbiota in allogeneic hematopoietic stem cell transplantation
Chang, C.-C., Hayase, E., & Jenq, R. R. (2021) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2021.1872541 · Cited by 20
Self-citationHeston, S. M., Young, R. R., Jenkins, K. E. H., Martin, P. L., Stokhuyzen, A., Ward, D. V., Bhattarai, S. K., Bucci, V., Arshad, M., Chao, N. J. A., et al. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2333748 · Cited by 22
Microbiome Anomalies in Allogeneic Hematopoietic Cell Transplantation
Schwabkey, Z. I., & Jenq, R. R. (2020) · Annual Review of Medicine · doi:10.1146/annurev-med-052918-122440 · Cited by 22
Self-citationAntimicrobial therapy during cancer treatment: Beyond antibacterial effects
Ghanem, S., Kim, C. J., Dutta, D., Salifu, M. O., & Lim, S. H. (2020) · Journal of Internal Medicine · doi:10.1111/joim.13238 · Cited by 23
Papanicolas, L. E., Sims, S. K., Taylor, S., Miller, S. J., Karapetis, C. S., Wesselingh, S. L., Gordon, D., & Rogers, G. B. (2021) · BMC Cancer · doi:10.1186/s12885-021-08296-4 · Cited by 22
de Molla, V. C., Heidrich, V., Bruno, J. S., Knebel, F. H., Miranda‐Silva, W., Asprino, P. F., Tucunduva, L. T. C. D. M., Rocha, V., Novis, Y. A. S., Camargo, A. A., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-96939-8 · Cited by 22
de Mooij, C. E. M., van der Velden, W. J. F. M., de Haan, A. F. J., Fazel, S., van Groningen, L. F. J., & Blijlevens, N. M. A. (2022) · Bone Marrow Transplantation · doi:10.1038/s41409-022-01719-1 · Cited by 22
Zinter, M. S., Dvorak, C. C., Mayday, M. Y., Reyes, G. A., Simon, M. R., Pearce, E. M., Kim, H., Shaw, P. J., Rowan, C. M., Auletta, J. J., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-02999-4 · Cited by 21
Opportunities and Challenges for Gut Microbiota in Acute Leukemia
Ma, T., Chen, Y., Li, L., & Zhang, L. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.692951 · Cited by 21
Fujiwara, H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.703298 · Cited by 22
Khoruts, A., Hippen, K. L., Lemire, A. M., Holtan, S. G., Knights, D., & Young, J. H. (2016) · Translational research · doi:10.1016/j.trsl.2016.07.013 · Cited by 21
Kornblit, B. T., & Müller, K. (2016) · Bone Marrow Transplantation · doi:10.1038/bmt.2016.263 · Cited by 21
Farowski, F., Bücker, V., Vehreschild, J. J., Biehl, L. M., Aguilar, R. C., Scheid, C., Holtick, U., Jazmati, N., Wisplinghoff, H., Cornely, O. A., et al. (2017) · Bone Marrow Transplantation · doi:10.1038/bmt.2017.203 · Cited by 21
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Dandoy, C. E., & Badia, P. (2019) · Bone Marrow Transplantation · doi:10.1038/s41409-019-0489-1 · Cited by 22
Fiorenza, S., & Turtle, C. J. (2021) · Immunometabolism · doi:10.20900/immunometab20210004 · Cited by 20
Spindelboeck, W., Halwachs, B., Bayer, N., Huber-Kraßnitzer, B., Schulz, E., Uhl, B., Gaksch, L., Hatzl, S., Bachmayr, V., Kleißl, L., et al. (2021) · Therapeutic Advances in Hematology · doi:10.1177/20406207211058333 · Cited by 21
Recent advances in neutropenic enterocolitis: Insights into the role of gut microbiota
Kapandji, N., Azoulay, É., & Zafrani, L. (2022) · Blood Reviews · doi:10.1016/j.blre.2022.100944 · Cited by 20
Weber, D., Hiergeist, A., Weber, M., Ghimire, S., Salzberger, B., Wolff, D., Poeck, H., Gessner, A., Edinger, M., Herr, W., et al. (2023) · Clinical Infectious Diseases · doi:10.1093/cid/ciad389 · Cited by 20
Self-citationOral inflammation and microbiome dysbiosis exacerbate chronic graft-versus-host disease
Kambara, Y., Fujiwara, H., Yamamoto, A., Gotoh, K., Tsuji, S., Kunihiro, M., Oyama, T., Terao, T., Sato, A., Tanaka, T., et al. (2024) · Blood · doi:10.1182/blood.2024024540 · Cited by 20
Immune function and dysfunction are determined by lymphoid tissue efficacy
Makris, S., de Winde, C. M., Horsnell, H. L., Cantoral-Rebordinos, J. A., Finlay, R. E., & Acton, S. E. (2022) · Disease Models & Mechanisms · doi:10.1242/dmm.049256 · Cited by 20
Pianko, M. J., & Golob, J. L. (2022) · Cancer and Metastasis Reviews · doi:10.1007/s10555-022-10033-7 · Cited by 20
Murthy, H. S., Gharaibeh, R. Z., Al‐Mansour, Z., Kozlov, A., Trikha, G., Newsome, R. C., Gauthier, J., Farhadfar, N., Wang, Y., Kelly, D. L., et al. (2020) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2020.07.023 · Cited by 19
Hueso, T., Coiteux, V., Curt, M. J.-C., Labreuche, J., Jouault, T., Yakoub‐Agha, I., & Séguy, D. (2017) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2017.03.005 · Cited by 19
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Socié, G. (2025) · Blood · doi:10.1182/blood.2025028617 · Cited by 18
Che, Y., Han, J., Harkins, C. P., Hou, P., Conlan, S., Deming, C., Amirkhani, A., Bingham, M. A., Holmes, C. J., Englander, H. E., et al. (2025) · Cell Host & Microbe · doi:10.1016/j.chom.2025.07.002 · Cited by 17
Göttert, S., Orberg, E. T., Fan, K., Heinrich, P., Matthe, D. M., Khalid, O., Klostermeier, L., Suriano, C., Strieder, N., Gebhard, C., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65180-6 · Cited by 22
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Yang, B., Zhang, X., Gong, H., Huang, Y., Wang, C., Liu, H., Dong, C., Ma, S., Wu, X., & Wu, D. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00600-9 · Cited by 18
Majumdar, A., Shah, M. R., Park, J. J., Narayanan, N., Kaye, K. S., & Bhatt, P. J. (2023) · Antibiotics · doi:10.3390/antibiotics12030592 · Cited by 18
Maurer, K., & Soiffer, R. J. (2023) · Expert Review of Hematology · doi:10.1080/17474086.2023.2273847 · Cited by 18
Nguyen, C. L., Docampo, M. D., van den Brink, M. R. M., & Markey, K. A. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.11.007 · Cited by 17
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Yoshioka, K., Kakihana, K., Doki, N., & Ohashi, K. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.05.028 · Cited by 18
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He, Y., Zhang, Y., Yang, D., Luo, H., & Zhou, Y. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07407-0 · Cited by 18
van Lier, Y. F., van den Brink, M. R. M., Hazenberg, M. D., & Markey, K. A. (2021) · Haematologica · doi:10.3324/haematol.2020.270835 · Cited by 18
Elgarten, C. W., Tanes, C., Lee, J., Danziger‐Isakov, L. A., Grimley, M. S., Green, M., Michaels, M. G., Barnum, J. L., Ardura, M. I., Auletta, J. J., et al. (2021) · Pediatric Blood & Cancer · doi:10.1002/pbc.29384 · Cited by 17
Wardill, H. R., de Mooij, C. E. M., Ferreira, A. R. D. S., Havinga, H., Harmsen, H. J. M., van der Velden, W. J. F. M., van Groningen, L. F. J., Tissing, W. J. E., & Blijlevens, N. M. A. (2022) · Scientific Reports · doi:10.1038/s41598-022-10700-3 · Cited by 17
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Dougé, A., Ravinet, A., Corriger, A., Cabrespine, A., Wasiak, M., Pereira, B., Sokol, H., Nguyen, S., & Bay, J. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-068480 · Cited by 17
Habibi, S., & Rashidi, A. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2229567 · Cited by 17
Gut microbiota and its implications in small bowel transplantation
Wang, C., Li, Q., & Li, J. (2018) · Frontiers of Medicine · doi:10.1007/s11684-018-0617-0 · Cited by 17
Autologous Stem Cell Transplantation for Myeloma: Cytoreduction or an Immunotherapy?
Minnie, S. A., & Hill, G. R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.651288 · Cited by 17
Shono, Y., & van den Brink, M. R. M. (2017) · Blood Advances · doi:10.1182/bloodadvances.2017005108 · Cited by 17
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Rashidi, A., Kaiser, T., Holtan, S. G., Weisdorf, D. J., Khoruts, A., & Staley, C. M. (2018) · Bone Marrow Transplantation · doi:10.1038/s41409-018-0414-z · Cited by 17
Malard, F., Thépot, S., Cluzeau, T., Carré, M., Lebon, D., Bories, P., Legrand, O., Schwarz, M., Loschi, M. L., Meunier, M., et al. (2025) · Blood Advances · doi:10.1182/bloodadvances.2024015571 · Cited by 18
Ball, J., Clear, A. J., Aries, J. A., Charrot, S., Besley, C., Mee, M., Stagg, A. J., Lindsay, J. O., Cavenagh, J. D., Calaminci, M., et al. (2020) · Blood · doi:10.1182/blood.2020005170 · Cited by 16
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Mengwasser, J., Babes, L., Cordes, S., Mertlitz, S., Riesner, K., Shi, Y., McGearey, A., Kalupa, M., Reinheckel, T., & Penack, O. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00203 · Cited by 16
Herpes simplex virus infection, Acyclovir and IVIG treatment all independently cause gut dysbiosis
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Costantini, C., Nunzi, E., Spolzino, A., Palmieri, M., Renga, G., Zelante, T., Englmaier, L., Coufalíková, K., Spáčil, Z., Borghi, M., et al. (2021) · Infection and Immunity · doi:10.1128/iai.00105-21 · Cited by 16
Daoud-Asfour, H., Henig, I. J., Ghersin, I., Rakedzon, S., Stern, A., Pitashny, M., Zuckerman, T., & Bar‐Yoseph, H. (2021) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2021.12.012 · Cited by 16
Haddad, L. E., Angelidakis, G., Clark, J. R., Mendoza, J. F., Terwilliger, A. L., Chaftari, C. P., Duna, M., Yusuf, S. T., Harb, C. P., Stibich, M., et al. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14081591 · Cited by 16
Rashidi, A., Kaiser, T., Holtan, S. G., Rehman, T. U., Weisdorf, D. J., Khoruts, A., & Staley, C. M. (2019) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2019.12.722 · Cited by 16
Shang, T., Zhang, R., Liu, Y., & Shi, S. (2025) · Gut Pathogens · doi:10.1186/s13099-025-00783-4 · Cited by 16
Koh, A. Y. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006342 · Cited by 15
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Ardura, M. I. (2018) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2017.11.003 · Cited by 15
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D’Amico, F., Barone, M., Tavella, T., Rampelli, S., Brigidi, P., & Turroni, S. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220105121754 · Cited by 16
Bastard, Q. L., Chevallier, P., & Montassier, E. (2021) · World Journal of Gastroenterology · doi:10.3748/wjg.v27.i45.7792 · Cited by 14
Youngster, I., Eshel, A., Geva, M., Danylesko, I., Henig, I. J., Zuckerman, T., Fried, S., Yerushalmi, R., Shem‐Tov, N., Fein, J. A., et al. (2024) · Bone Marrow Transplantation · doi:10.1038/s41409-024-02198-2 · Cited by 15
Lewalle, P., Pochon, C., Michallet, M., Turlure, P., Brissot, É., Paillard, C., Puyade, M., Roth-Guépin, G., Yakoub‐Agha, I., & Chantepie, S. (2019) · Bulletin du Cancer · doi:10.1016/j.bulcan.2018.08.017 · Cited by 14
Jabr, R., Atrouni, W. E., Shune, L. O., Telfah, M., Gao, G., He, J., Abhyankar, S., McGuirk, J. P., & Clough, L. A. (2020) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2020.10.009 · Cited by 14
Kouidhi, S., Souai, N., Zidi, O., Mosbah, A., Lakhal, A., Othmane, T. B., Belloumi, D., Ayed, F. B., Asimakis, E. D., Stathopoulou, P. M., et al. (2021) · Microorganisms · doi:10.3390/microorganisms9091845 · Cited by 14
Chhabra, S., Szabó, A., Clurman, A. G., McShane, K., Waters, N. R., Eastwood, D. C., Samanas, L., Fei, T., Armijo, G. K., Abedin, S., et al. (2022) · Haematologica · doi:10.3324/haematol.2022.281309 · Cited by 14
Self-citationStohs, E. J., Chow, V. A., Liu, C., Bourassa, L. A., Miles-Jay, A., Knight, J., Sweet, A., Storer, B. E., Mielcarek, M. B., & Pergam, S. A. (2019) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2019.01.031 · Cited by 14
Self-citationYan, J., Liao, C., Taylor, B. P., Fontana, E., Amoretti, L. A., Wright, R. J., Littmann, E. R., Dai, A., Waters, N. R., Peled, J. U., et al. (2022) · Scientific Data · doi:10.1038/s41597-022-01302-9 · Cited by 21
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Winner, K. M., Chanderraj, R., Nuppnau, M., He, Y., Petouhoff, A., Falkowski, N. R., Woods, R. J., Schaub, J. A., Heung, M., Ranjan, P., et al. (2025) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202411-2281oc · Cited by 13
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Poto, R., Ianiro, G., de Paulis, A., Spadaro, G., Marone, G., Gasbarrini, A., & Varricchi, G. (2023) · Clinical and Experimental Medicine · doi:10.1007/s10238-023-01006-3 · Cited by 16
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Malard, F., & Jenq, R. R. (2023) · The Cancer Journal · doi:10.1097/ppo.0000000000000645 · Cited by 14
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Yang, Q. Z., Wei, Y., Zhu, Y., Guo, J., Zhang, J., He, Y., Li, X., Liu, J., & Zhou, W. (2023) · Cancers · doi:10.3390/cancers15071942 · Cited by 13
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Fortman, D. D., Hurd, D. E., & Davar, D. (2023) · Current Oncology Reports · doi:10.1007/s11912-023-01431-3 · Cited by 14
Gottesdiener, L. S., & Satlin, M. J. (2023) · Transplant Infectious Disease · doi:10.1111/tid.14169 · Cited by 15
Neuerburg, C., Schmitz, F., Schmitz, M., Rehnelt, S., Schumacher, M., Parčina, M., Schmid, M., Wolf, D. G. F., Brossart, P., & Holderried, T. A. W. (2024) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2024.09.011 · Cited by 13
Din, M. A. U., Lin, Y., Lyu, C., Yi, C., Fang, A., & Mao, F. (2025) · Molecular Medicine · doi:10.1186/s10020-024-01060-x · Cited by 13
Metadata
- Authors
- Shono, Y., Docampo, M. D., Peled, J. U., Perobelli, S. M., Velardi, E., Tsai, J. J., Slingerland, A. E., Smith, O. M., Young, L. F., Gupta, J., Lieberman, S. R., Jay, H. V., Ahr, K. F., Porosnicu Rodriguez, K. A., Xu, K., Calarfiore, M., Poeck, H., Caballero, S., Devlin, S. M., Rapaport, F., Dudakov, J. A., Hanash, A. M., Gyurkocza, B., Murphy, G. F., Gomes, C., Liu, C., Moss, E. L., Falconer, S. B., Bhatt, A. S., Taur, Y., Pamer, E. G., van den Brink, M. R. M., & Jenq, R. R.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
- Program in Dermatopathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
- Brigham and Women's Hospital (US)
- Rutgers, The State University of New Jersey (US)
- Stanford University (US)
- Corresponding author
- Shono, Yusuke
- Jenq, Robert R.
- ORCID
- Shono, Yusuke
- Docampo, Melissa D.
- Peled, Jonathan U.
- Perobelli, Suelen M.
- Velardi, Enrico
- Tsai, Jennifer J.
- Slingerland, Ann E.
- Young, Lauren F.
- Lieberman, Sophia R.
- Ahr, Katya F.
- Xu, Ke
- Poeck, Hendrik
- Devlin, Sean M.
- Dudakov, Jarrod A.
- Hanash, Alan M.
- Gyurkocza, Boglarka
- Gomes, Camilla
- Liu, Chen
- Bhatt, Ami S.
- Taur, Ying
- Pamer, Eric G.
- Jenq, Robert R.
- Venue
- Science Translational Medicine
- Published
- 2016-05-18
- Volume
- 8
- Issue
- 339
- Pages
- 339ra71-339ra71
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4991773
- OpenAlex
- W2407774696
- Cited by
- 592
- References
- 78
- Citations by year
- 2026: 49 · 2025: 70 · 2024: 47 · 2023: 61 · 2022: 58 · 2021: 81 · 2020: 65 · 2019: 50 · 2018: 50 · 2017: 47 · 2016: 14
- FWCI
- 51.07
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Funders
- NIH (R01-HL069929, R01-AI100288, R01-AI080455, R01-AI101406, R00-CA176376, R01-HL124112)
- Radiation Effects Research Foundation_National Institute of Allergy and Infectious Diseases
- American Society for Blood and Marrow Transplantation
- Australian National Health
- Medical Research Council
- American Society of Hematology
- DKMS (German Bone Marrow Donor Center) Foundation for Giving Life
- Lymphoma Foundation
- NCI (P30-CA008748)
- NIH Cancer Center Support (P30 CA008748-48)
- Topics
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Health Sciences › Medicine › Oncology › Neutropenia and Cancer Infections
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- graft-versus-host disease, allogeneic hematopoietic stem cell transplantation, broad-spectrum antibiotics, imipenem/cilastatin, piperacillin-tazobactam, aztreonam, cefepime, febrile neutropenia, gut microbiota, Akkermansia muciniphila, intestinal mucus barrier, intestinal barrier function, short-chain fatty acids, regulatory T cells
- MeSH terms
- Gastrointestinal Microbiome, Piperacillin, Tazobactam Drug Combination, Cilastatin, Imipenem Drug Combination, Animals, Anti-Bacterial Agents, Colon, Drug Combinations, Feces, Female, Flow Cytometry, Graft vs Host Disease, Humans, Mice, Inbred C57BL, Penicillanic Acid, Phylogeny, Piperacillin, Transplantation, Homologous, Cilastatin, Imipenem, CD4-Positive T-Lymphocytes, Hematopoietic Stem Cell Transplantation, Mice, Interleukin-23, Verrucomicrobia
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