Cited by 326Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology ResearchAutism Spectrum Disorder Research

The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2 -deficient mice

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Abstract

Using optogenetics to modulate the excitation/inhibition balance in the prefrontal cortex of an autism-like mouse model rescued social behavior deficits.

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Crossref · 10.1126/scitranslmed.aah6733

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Metadata

Authors
Selimbeyoglu, A., Kim, C. K., Inoue, M., Lee, S. Y., Hong, A. S. O., Kauvar, I., Ramakrishnan, C., Fenno, L. E., Davidson, T. J., Wright, M., & Deisseroth, K.
Affiliations
  • Stanford University (US)
  • Stanford Medicine (US)
  • Howard Hughes Medical Institute (US)
Corresponding author
Deisseroth, Karl
Venue
Science Translational Medicine
Published
2017-08-02
Volume
9
Issue
401
ISSN
  • 1946-6234 (ISSN-L)
  • 1946-6242
OpenAlex
W2740920123
Cited by
326
References
47
Citations by year
2026: 30 · 2025: 40 · 2024: 34 · 2023: 35 · 2022: 37 · 2021: 45 · 2020: 41 · 2019: 38 · 2018: 24 · 2017: 2
FWCI
19.06
Type
journal article
Language
en
Open access
Locations
  • Science Translational Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
Howard Hughes Medical Institute (award299942, None)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Keywords
CNTNAP2, prefrontal cortex, excitation-inhibition balance, social behavior, autism spectrum disorder, knockout mice, neural circuit modulation, social dysfunction
MeSH terms
Animals, Autistic Disorder, Behavior, Animal, Genetic Engineering, Membrane Proteins, Mice, Inbred C57BL, Movement, Nerve Tissue Proteins, Neurons, Parvalbumins, Social Behavior, Prefrontal Cortex, Mice, Knockout, Opsins

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