The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates
Abstract
Liver-targeted mitochondrial uncoupling improves dyslipidemia and reduces hepatic triglyceride content in obese nonhuman primates.
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“| | Primates | Spontaneous or diet-induced obesity in cynomolgus and rhesus macaques, treated with CRMP | Enhanced hepatic mitochondrial fat oxidation, improved insulin tolerance, reduced hepatic and plasma triglycerides, reduced cholesterol | 168 |”
From Hallmarks of aging: An expanding universe (2023) · cites this paper as [168]
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In the citing paper
“In non-human primate models including spontaneously obese rhesus macaques and high-fat, high-fructose-fed cynomolgus macaques, CRMP reverses signs of metabolic syndrome and improves fatty acid oxidation 168 .”
From Hallmarks of aging: An expanding universe (2023) · cites this paper as [168]
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Citations
Cites
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Self-citationMitochondrial proton and electron leaks
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Self-citationControlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
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Cited by
Sorted by citations
Hallmarks of aging: An expanding universe
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2023) · Cell · doi:10.1016/j.cell.2022.11.001 · Cited by 6,549
Mitochondrial and metabolic dysfunction in ageing and age-related diseases
Amorim, J. A., Coppotelli, G., Rolo, A. P., Palmeira, C. M., Ross, J. M., & Sinclair, D. A. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00626-7 · Cited by 990
Ins and outs of the TCA cycle: the central role of anaplerosis
Inigo, M., Deja, S., & Burgess, S. C. (2021) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-120420-025558 · Cited by 189
Metadata
- Authors
- Goedeke, L., Peng, L., Montalvo-Romeral, V., Butrico, G. M., Dufour, S., Zhang, X.-M., Perry, R. J., Cline, G. W., Kievit, P., Chng, K., Petersen, K. F., & Shulman, G. I.
- Affiliations
- Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
- Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
- Crown Bioscience Louisiana Inc., New Iberia, LA 70560, USA.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2019-10-02
- Volume
- 11
- Issue
- 512
- ISSN
- 1946-6234
- 1946-6242
- PMC
- PMC6996238
- Cited by
- 63
- References
- 14
- Language
- en
- Funders
- National Institutes of Health (P51-OD-011092)
- National Cancer Institute (K99 CA-215315)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK-113984, R01 DK119968, P30 DK045735, F32 DK-114954)
- Gilead Sciences (N/A)
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