Metschnikowia Strains Isolated from Botrytized Grapes Antagonize Fungal and Bacterial Growth by Iron Depletion
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Noble-rotted grapes are colonized by complex microbial populations. I isolated pigment-producing Metschnikowia strains from noble-rotted grapes that had antagonistic activity against filamentous fungi, yeasts, and bacteria. A red-maroon pigment was formed from a diffusible colorless precursor released by the cells into the medium. The conversion of the precursor required iron and could occur both in the cells (red colonies) and in the medium (red halos around colonies). The intensity of pigmentation was correlated with the intensity of the antimicrobial activity. Mutants that did not form pigment also lacked antifungal activity. Within the pigmented halos, conidia of the sensitive fungi did not germinate, and their hyphae did not grow and frequently lysed at the tips. Supplementation of the medium with iron reduced the size of the halos and the inhibition zones, while it increased the pigment accumulation by the colonies. The iron-binding agent tropolone had a similar effect, so I hypothesize that pigmented Metschnikowia isolates inhibit the growth of the sensitive microorganisms by pigment formation, which depletes the free iron in the medium. As the pigment is a large nondiffusible complex produced in the presence of both low and high concentrations of ferric ions, the proposed mechanism is different from the mechanisms operating in microbes that release siderophores into the environment for iron acquisition.
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Pulcherrimin, an iron-binding pigment produced by M. pulcherrima, is believed to mediate its antagonistic activity against other fungi.
“Pulcherrimin, an iron-binding pigment produced by M. pulcherrima, is believed to mediate this antagonistic activity against other fungi [71–74].”
From Competition assays and physiological experiments of soil and phyllosphere yeasts identify Candida subhashii as a novel antagonist of filamentous fungi (2017) · cites this paper as [72]
Pigmentless M. pulcherrima mutants exhibit reduced antifungal activity, and iron deprivation of the fungal pathogen was suggested as one of several mechanisms by which this yeast antagonises plant pathogenic fungi.
“Pigmentless M. pulcherrima mutants were shown to exhibit reduced antifungal activity and iron deprivation of the fungal pathogen was suggested as one of several mechanisms by which this yeast antagonises plant pathogenic fungi (Gore-Lloyd et al. 2019; Sipiczki 2006).”
From Biocontrol yeasts: mechanisms and applications (2019) · cites this paper as Sipiczki 2006
Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589 · see citing works
A medium for the cultivation of lactobacilli
De MAN, J. C., ROGOSA, M., & SHARPE, M. E. (1960) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1960.tb00188.x · Cited by 5,311 · see citing works
Kurtzman, C. P., & Lodder, J. (1972) · Mycologia · doi:10.2307/3758036 · Cited by 3,441 · see citing works
Siderophores: Structure and Function of Microbial Iron Transport Compounds
Neilands, J. B. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26723 · Cited by 1,652 · see citing works
Wine Microbiology and Biotechnology
Fleet, G. H. (1993) · Cited by 1,378 · see citing works
Food spoilage—interactions between food spoilage bacteria
Gram, L., Flodgaard, L. R., Rasch, M., Bruhn, J. B., Christensen, A. B., & Givskov, M. (2002) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(02)00233-7 · Cited by 1,061 · see citing works
The Fungal Holomorph: Mitotic, Meiotic and Pleomorphic Speciation in Fungal Systematics
Reynolds, D. R., & Taylor, J. R. (1993) · Cited by 973 · see citing works
Fusarium and its near relatives
O’Donnell, K. (1993) · Medical Entomology and Zoology · Cited by 768 · see citing works
Lactic acid bacteria in the quality improvement and depreciation of wine
Lonvaud‐Funel, A. (1999) · Antonie van Leeuwenhoek · doi:10.1023/a:1002088931106 · Cited by 555 · see citing works
Lactic acid bacteria in the quality improvement and depreciation of wine
Lonvaud‐Funel, A. (1999) · Springer eBooks · doi:10.1007/978-94-017-2027-4_16 · Cited by 526 · see citing works
Methods for the isolation, maintenance, classification and identification of yeasts
van der Walt, J. P., & Yarrow, D. (1984) · Elsevier eBooks · doi:10.1016/b978-0-444-80421-1.50009-7 · Cited by 475 · see citing works
State of the art and future prospects of the biological control of postharvest fruit diseases
Spadaro, D., & Gullino, M. L. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(03)00380-5 · Cited by 364 · see citing works
Saprotrophic Cord-Forming Fungi: Meeting the Challenge of Heterogeneous Environments
Boddy, L. (1999) · Mycologia · doi:10.1080/00275514.1999.12060990 · Cited by 318 · see citing works
Microbial siderophore-mediated transport.
Winkelmann, G. (2002) · Biochemical Society Transactions · doi:10.1042/bst0300691 · Cited by 301 · see citing works
Prakitchaiwattana, C., Fleet, G. H., & Heard, G. M. (2004) · FEMS Yeast Research · doi:10.1016/j.femsyr.2004.05.004 · Cited by 293 · see citing works
Yeast Diversity and Persistence in Botrytis-Affected Wine Fermentations
Mills, D. A., Johannsen, E., & Cocolin, L. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.10.4884-4893.2002 · Cited by 260 · see citing works
Acquisition, Transport, and Storage of Iron by Pathogenic Fungi
Howard, D. H. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.3.394 · Cited by 260 · see citing works
Crosa, J. H. (1997) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.61.3.319-336.1997 · Cited by 256 · see citing works
Clemente-Jiménez, J. M., Mingorance‐Cazorla, L., Martínez‐Rodríguez, S., Heras‐Vázquez, F. J. L., & Rodríguez‐Vico, F. (2004) · Food Microbiology · doi:10.1016/s0740-0020(03)00063-7 · Cited by 241 · see citing works
Combina, M., Elía, A., Mercado, L. A., Catania, C. D., Ganga, M. A., & Martı́nez, C. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.08.017 · Cited by 218 · see citing works
Spadaro, D., Vola, R., Piano, S., & Gullino, M. L. (2002) · Postharvest Biology and Technology · doi:10.1016/s0925-5214(01)00172-7 · Cited by 186 · see citing works
Lactic acid bacteria in the quality improvement and depreciation of wine.
Lonvaud‐Funel, A. (1999) · PubMed · Cited by 177 · see citing works
Kurtzman, C. P., & Droby, S. (2001) · Systematic and Applied Microbiology · doi:10.1078/0723-2020-00045 · Cited by 175 · see citing works
Postharvest biological control of Penicillium rots of citrus with antagonistic yeasts and bacteria
Wilson, C. L., & Chalutz, E. (1989) · Scientia Horticulturae · doi:10.1016/0304-4238(89)90092-7 · Cited by 168 · see citing works
Sipiczki, M. (2003) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.02649-0 · Cited by 157 · see citing works
Self-citationKarabulut, O. A., Smilanick, J. L., Gabler, F. M., Mansour, M., & Droby, S. (2003) · Plant Disease · doi:10.1094/pdis.2003.87.11.1384 · Cited by 139 · see citing works
Biocontrol capability of Metschnikowia pulcherrima against Botrytis postharvest rot of apple
Piano, S., Neyrotti, V., Migheli, Q., & Gullino, M. L. (1997) · Postharvest Biology and Technology · doi:10.1016/s0925-5214(97)00022-7 · Cited by 136 · see citing works
Biodiversity and Biotechnology of Wine Yeasts
Ciani, M. (2002) · Cited by 131 · see citing works
Fan, Q., & Tian, S. (2001) · Postharvest Biology and Technology · doi:10.1016/s0925-5214(00)00182-4 · Cited by 130 · see citing works
Pulcherrimin, The Pigment of Candida Pulcherrima
Kluyver, A. J., van der Walt, J. P., & van Triet, A. J. (1953) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.39.7.583 · Cited by 105 · see citing works
The yeast ecology of wine grapes.
Fleet, G. H., Prakitchaiwattana, C., Beh, A., Heard, G. M., & Ciani, M. (2002) · Cited by 102 · see citing works
Cellular and Extracellular Siderophores of Aspergillus nidulans and Penicillium chrysogenum
Charlang, G., Ng, B., Horowitz, N. H., & Horowitz, R. M. (1981) · Molecular and Cellular Biology · doi:10.1128/mcb.1.2.94-100.1981 · Cited by 99 · see citing works
Calvente, V. E., Benuzzi, D., & de Tosetti, M. I. S. (1999) · International Biodeterioration & Biodegradation · doi:10.1016/s0964-8305(99)00046-3 · Cited by 99 · see citing works
Muckenschnabel, I., Goodman, B. A., Williamson, B. D., Lyon, G. D., & Deighton, N. (2002) · Journal of Experimental Botany · doi:10.1093/jexbot/53.367.207 · Cited by 97 · see citing works
Sansone, G., Rezza, I., Calvente, V. E., Benuzzi, D., & de Tosetti, M. I. S. (2005) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2004.09.005 · Cited by 95 · see citing works
Deighton, N., Muckenschnabel, I., Goodman, B. A., & Williamson, B. D. (1999) · The Plant Journal · doi:10.1046/j.1365-313x.1999.00622.x · Cited by 95 · see citing works
A vegetative cycle of Pullularia pullulans
Ramos, S., & Acha, I. G. (1975) · Transactions of the British Mycological Society · doi:10.1016/s0007-1536(75)80083-0 · Cited by 91 · see citing works
Sodium bicarbonate enhances biocontrol efficacy of yeasts on fungal spoilage of pears
Yao, H., Tian, S., & Wang, Y. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2003.11.011 · Cited by 88 · see citing works
Qin, G., Tian, S., & Xu, Y. (2003) · Postharvest Biology and Technology · doi:10.1016/s0925-5214(03)00130-3 · Cited by 87 · see citing works
Biosynthesis of pulcherriminic acid
MacDonald, J. P. (1965) · Biochemical Journal · doi:10.1042/bj0960533 · Cited by 84 · see citing works
BIOCONTROL ACTIVITY OF ANTAGONISTIC YEASTS AGAINST PENICILLIUM EXPANSUM ON APPLE
(2003) · Journal of Plant Pathology · doi:10.4454/jpp.v85i3.1032 · Cited by 79 · see citing works
Role of botrytized grape micro-organisms in SO2binding phenomena
Barbe, J., de Revel, G., Joyeu×, A., Bertrand, A., & Lonvaud‐Funel, A. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01200.x · Cited by 71 · see citing works
Gradual genome stabilisation by progressive reduction of the genome in an interspecific hybrid with
Antunovics, Z., NGUYEN, H., Gaillardin, C. M., & Sipiczki, M. (2005) · FEMS Yeast Research · doi:10.1016/j.femsyr.2005.04.008 · Cited by 68 · see citing works
Self-citationMicrobiology and Biotechnology
Lowrie, P., & Wells, S. (2000) · Cited by 63 · see citing works
Coulanges, V., André, P., & Vidon, D. J.-M. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9184 · Cited by 61 · see citing works
Microbial antagonists control postharvest black rot of pineapple fruit
Reyes, M. E. Q., Rohrbach, K. G., & Paull, R. E. (2004) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2004.02.003 · Cited by 49 · see citing works
798. The structure of pulcherrimin
Cook, A. H., & Slater, C. A. (1956) · Journal of the Chemical Society (Resumed) · doi:10.1039/jr9560004133 · Cited by 48 · see citing works
Influence of Tropolone on Poria placenta Wood Degradation
Diouf, P. N., Delbarre, N., Perrin, D., Gérardin, P., Rapin, C., Jacquot, J., & Gelhaye, É. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.9.4377-4382.2002 · Cited by 45 · see citing works
The yeast Metschnikowia pulcherrima has an inhibitory effect against various yeast species
Nguyen, H. V., & Panon, G. (1998) · HAL (Le Centre pour la Communication Scientifique Directe) · Cited by 34 · see citing works
Molecular and genetic analysis of the yeast flora of botrytized Tokaj wines
Antunovics, Z. (2003) · Bulletin de l' OIV: Revue Internatione de Viticulture, Oenologie, Economie, droit viti-vinicole · Cited by 29 · see citing works
Enzymic methods for enrichment of fungal mutants I. Enrichment of Schizosaccharomyces pombe mutants
Sipiczki, M., & Ferenczy, L. (1978) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(78)90021-0 · Cited by 28 · see citing works
Self-citationFreeze—desiccation survival in wild yeasts in the bloom of icewine grapes
Chamberlain, G., Husnik, J. I., & Subden, R. E. (1997) · Food Research International · doi:10.1016/s0963-9969(97)00070-7 · Cited by 25 · see citing works
Rousseau, S., & Donèche, B. B. (2015) · Vitis · doi:10.5073/vitis.2001.40.75-78 · Cited by 23 · see citing works
The Minisatellite MSB1, in the Fungus Botrytis cinerea, Probably Mutates by Slippage
Giraud, T., Fortini, D., Levis, C., & Brygoo, Y. (1998) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025880 · Cited by 23 · see citing works
Assessment of phenotypic and genetic diversity in the yeast genusMetschnikowia
Giménez‐Jurado, G., Valderrama, M. J., Sá‐Nogueira, I., & Spencer‐Martins, I. (1995) · Antonie van Leeuwenhoek · doi:10.1007/bf00873097 · Cited by 19 · see citing works
Auerbach, C. (1978) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(78)90019-2 · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 57 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Ecology and evolution of metabolic cross-feeding interactions in bacteria
D’Souza, G. G., Shitut, S., Preußger, D., Yousif, G., Waschina, S., & Kost, C. (2018) · Natural Product Reports · doi:10.1039/c8np00009c · Cited by 556 · see citing works
Review: Utilization of antagonistic yeasts to manage postharvest fungal diseases of fruit
Liu, J., Sui, Y., Wisniewski, M., Droby, S., & Liu, Y. (2013) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2013.09.004 · Cited by 521 · see citing works
Biocontrol yeasts: mechanisms and applications
Freimoser, F. M., Rueda-Mejia, M. P., Tilocca, B., & Migheli, Q. (2019) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-019-2728-4 · Cited by 462 · see citing works
“2019; Sipiczki 2006).”
Parafati, L., Vitale, A., Restuccia, C., & Cirvilleri, G. (2015) · Food Microbiology · doi:10.1016/j.fm.2014.11.013 · Cited by 391 · see citing works
Unravelling the Diversity of Grapevine Microbiome
Pinto, C., Pinho, D., Sousa, S., Pinheiro, M. M., Egas, C., & Gomes, A. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085622 · Cited by 291 · see citing works
The importance and ecology of yeasts in soil
Botha, A. (2011) · Soil Biology and Biochemistry · doi:10.1016/j.soilbio.2010.10.001 · Cited by 286 · see citing works
Saravanakumar, D., Ciavorella, A., Spadaro, D., Garibaldi, A., & Gullino, M. L. (2008) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2007.11.006 · Cited by 224 · see citing works
Wine microbiome: A dynamic world of microbial interactions
Liu, Y., Rousseaux, S., Tourdot‐Maréchal, R., Sadoudi, M., Gougeon, R. D., Schmitt‐Kopplin, P., & Alexandre, H. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.983591 · Cited by 224 · see citing works
Antimicrobial activity of Metschnikowia pulcherrima on wine yeasts
Oro, L., Ciani, M., & Comitini, F. (2014) · Journal of Applied Microbiology · doi:10.1111/jam.12446 · Cited by 218 · see citing works
The history, state of the art and future prospects for oleaginous yeast research
Abeln, F., & Chuck, C. J. (2021) · Microbial Cell Factories · doi:10.1186/s12934-021-01712-1 · Cited by 186 · see citing works
Guimarães, A., Abrunhosa, L., Pastrana, L. M., & Cerqueira, M. Â. (2018) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12345 · Cited by 188 · see citing works
Metabolic Remodeling during Biofilm Development of Bacillus subtilis
Pisithkul, T., Schroeder, J. W., Trujillo, E. A., Yeesin, P., Stevenson, D. M., Chaiamarit, T., Coon, J. J., Wang, J. D., & Amador‐Noguez, D. (2019) · mBio · doi:10.1128/mbio.00623-19 · Cited by 166 · see citing works
Mechanisms of Action of Microbial Biocontrol Agents against Botrytis cinerea
Roca-Couso, R., Flores‐Félix, J. D., & Rivas, R. (2021) · Journal of Fungi · doi:10.3390/jof7121045 · Cited by 183 · see citing works
Sipiczki, M. (2020) · Microorganisms · doi:10.3390/microorganisms8071029 · Cited by 183 · see citing works
Self-citationInfluence of dietary yeasts on Drosophila melanogaster life‐history traits
Anagnostou, C., Dorsch, M., & Rohlfs, M. (2010) · Entomologia Experimentalis et Applicata · doi:10.1111/j.1570-7458.2010.00997.x · Cited by 153 · see citing works
Applications of Metschnikowia pulcherrima in Wine Biotechnology
Morata, A., Loira, I., Escott, C., del Fresno, J. M., Bañuelos, M. A., & Suárez-Lepe, J. A. (2019) · Fermentation · doi:10.3390/fermentation5030063 · Cited by 146 · see citing works
Contribution of Non-Saccharomyces Yeasts to Wine Freshness. A Review
Morata, A., Escott, C., Bañuelos, M. A., Loira, I., del Fresno, J. M., González, C., & Suárez-Lepe, J. A. (2019) · Biomolecules · doi:10.3390/biom10010034 · Cited by 150 · see citing works
Zhang, D., Spadaro, D., Garibaldi, A., & Gullino, M. L. (2010) · Biological Control · doi:10.1016/j.biocontrol.2010.05.003 · Cited by 137 · see citing works
Alternative Methods to SO 2 for Microbiological Stabilization of Wine
Lisanti, M. T., Blaiotta, G., Nioi, C., & Luigi Moio, B. (2019) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12422 · Cited by 138 · see citing works
Belda, I., Ruíz, J., Alastruey‐Izquierdo, A., Navascués, E., Marquina, D., & Santos, A. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00012 · Cited by 130 · see citing works
Yeasts and yeast-like organisms associated with fruits and blossoms of different fruit trees
Vadkertiová, R., Molnárová, J., Vránová, D., & Sláviková, E. (2012) · Canadian Journal of Microbiology · doi:10.1139/cjm-2012-0468 · Cited by 127 · see citing works
Zhang, D., Spadaro, D., Garibaldi, A., & Gullino, M. L. (2011) · Biological Control · doi:10.1016/j.biocontrol.2011.02.011 · Cited by 125 · see citing works
Contreras, Á., Curtin, C. D., & Varela, C. (2014) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-014-6193-6 · Cited by 123 · see citing works
Kecskeméti, E., Berkelmann‐Löhnertz, B., & Reineke, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160852 · Cited by 121 · see citing works
Wild Grape-Associated Yeasts as Promising Biocontrol Agents against Vitis vinifera Fungal Pathogens
Cordero-Bueso, G. A., Mangieri, N., Maghradze, D., Foschino, R. C., Valdetara, F., Cantoral, J. M., & Vigentini, I. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02025 · Cited by 118 · see citing works
Krause, D. J., Kominek, J., Opulente, D. A., Shen, X., Zhou, X., Langdon, Q. K., DeVirgilio, J. H., Hulfachor, A. B., Kurtzman, C. P., Rokas, A., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1806268115 · Cited by 115 · see citing works
Blanco‐Ulate, B., Amrine, K. C. H., Collins, T. S., Rivero, R. M., Vicente, A. R., Morales‐Cruz, A., Doyle, C. L., Ye, Z., Allen, G., Heymann, H., et al. (2015) · PLANT PHYSIOLOGY · doi:10.1104/pp.15.00852 · Cited by 111 · see citing works
Hilber-Bodmer, M., Schmid, M., Ahrens, C. H., & Freimoser, F. M. (2017) · BMC Microbiology · doi:10.1186/s12866-016-0908-z · Cited by 106 · see citing works
Zhang, H., Mahunu, G. K., Castoria, R., Apaliya, M. T., & Yang, Q. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.08.020 · Cited by 107 · see citing works
Grapevine rootstock and soil microbiome interactions: Keys for a resilient viticulture
Darriaut, R., Lailheugue, V., Masneuf-Pomarède, I., Marguerit, E., Martins, G., Compant, S., Ballestra, P., Upton, S., Ollat, N., & Lauvergeat, V. (2022) · Horticulture Research · doi:10.1093/hr/uhac019 · Cited by 92 · see citing works
Yeasts from Different Habitats and Their Potential as Biocontrol Agents
Pretscher, J., Fischkal, T., Branscheidt, S., Jäger, L., Kahl, S., Schlander, M., Thines, E., & Claus, H. (2018) · Fermentation · doi:10.3390/fermentation4020031 · Cited by 104 · see citing works
Liu, Y., Yao, S., Deng, L., Ming, J., & Zeng, K. (2019) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2019.03.002 · Cited by 106 · see citing works
Zhimo, V. Y., Kumar, A., Biasi, A., Salim, S., Feygenberg, O., Toamy, M. A., Abdelfattah, A., Medina, S., Freilich, S., Wisniewski, M., et al. (2021) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2021.111469 · Cited by 103 · see citing works
Yeasts isolated from figs (Ficus carica L.) as biocontrol agents of postharvest fruit diseases
Ruiz-Moyano, S., Martín, A., Villalobos, M. C., Calle, A., Serradilla, M. J., Córdoba, M. G., & Hernández, A. (2016) · Food Microbiology · doi:10.1016/j.fm.2016.01.003 · Cited by 99 · see citing works
Gore‐Lloyd, D., Sumann, I., Brachmann, A. O., Schneeberger, K., Ortiz‐Merino, R. A., Moreno‐Beltrán, M., Schläfli, M., Kirner, P., Santos Kron, A., Rueda‐Mejia, M. P., et al. (2019) · Molecular Microbiology · doi:10.1111/mmi.14272 · Cited by 102 · see citing works
The Genus Metschnikowia in Enology
Vicente, J., Ruíz, J., Belda, I., Benito‐Vázquez, I., Marquina, D., Calderón, F., Santos, A., & Benito, S. (2020) · Microorganisms · doi:10.3390/microorganisms8071038 · Cited by 99 · see citing works
Millán, A. F., Larraya, L. M., Farrán, I., Ancín, M., & Veramendi, J. (2021) · Biological Control · doi:10.1016/j.biocontrol.2021.104683 · Cited by 98 · see citing works
Yeast–Bacterium Interactions: The Next Frontier in Nectar Research
Álvarez‐Pérez, S., Lievens, B., & Fukami, T. (2019) · Trends in Plant Science · doi:10.1016/j.tplants.2019.01.012 · Cited by 92 · see citing works
Barbosa, C. R., Lage, P., Esteves, M., Chambel, L., Mendes‐Faia, A., & Mendes‐Ferreira, A. (2018) · Fermentation · doi:10.3390/fermentation4010008 · Cited by 91 · see citing works
Prevention of fungal spoilage in food products using natural compounds: A review
Ribes, S., Fuentes, A., Talens, P., & Baviera, J. M. B. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1295017 · Cited by 91 · see citing works
Liu, Y., Wang, W., Zhou, Y., Yao, S., Deng, L., & Zeng, K. (2017) · Biological Control · doi:10.1016/j.biocontrol.2017.04.002 · Cited by 85 · see citing works
Metschnikowia andauensis as a new biocontrol agent of fruit postharvest diseases
Manso, T., & Nunes, C. (2011) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2011.02.004 · Cited by 85 · see citing works
David, V., Terrat, S., Herzine, K., Claisse, O., Rousseaux, S., Tourdot‐Maréchal, R., Masneuf‐Pomarède, I., Ranjard, L., & Alexandre, H. (2014) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-014-1427-2 · Cited by 81 · see citing works
Schoonvaere, K., Smagghe, G. J., Francis, F., & de Graaf, D. C. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00177 · Cited by 83 · see citing works
Wang, S., Ruan, C., Yi, L., Deng, L., Yao, S., & Zeng, K. (2019) · Food Microbiology · doi:10.1016/j.fm.2019.103375 · Cited by 83 · see citing works
Magyar, I. (2011) · Advances in food and nutrition research · doi:10.1016/b978-0-12-384927-4.00006-3 · Cited by 79 · see citing works
Öztekin, S., Dikmetaş, D. N., Devecioğlu, D., Acar, E. G., & Karbancıoğlu‐Güler, F. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c00315 · Cited by 79 · see citing works
Biocontrol capability of local Metschnikowia sp. isolates
Pawlikowska, E., James, S. A., Breierová, E., Antolak, H., & Kręgiel, D. (2019) · Antonie van Leeuwenhoek · doi:10.1007/s10482-019-01272-w · Cited by 74 · see citing works
Türkel, S., & Ener, B. (2009) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2009-5-618 · Cited by 74 · see citing works
Seguinot, P., Ortiz-Julien, A., & Camarasa, C. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00305 · Cited by 70 · see citing works
Jindo, K., Goron, T. L., Pizarro‐Tobías, P., Sanchez-Monedero, M. A., Audette, Y., Deolu‐Ajayi, A. O., van der Werf, A., Teklu, M. G., Shenker, M., Sudré, C. P., et al. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.932311 · Cited by 75 · see citing works
Sipiczki, M. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00212 · Cited by 69 · see citing works
Self-citationMetschnikowia: half tetrads, a regicide and the fountain of youth
Lachance, M. (2016) · Yeast · doi:10.1002/yea.3208 · Cited by 68 · see citing works
Piombo, E., Sela, N., Wisniewski, M., Hoffmann, M., Gullino, M. L., Allard, M. W., Levin, E., Spadaro, D., & Droby, S. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00593 · Cited by 68 · see citing works
Liu, X., Gao, Y. W., Yang, H., Li, L., Jiang, Y., Li, Y., & Zheng, J. (2019) · Food Microbiology · doi:10.1016/j.fm.2019.103404 · Cited by 66 · see citing works
Paiva, E. D. S., Serradilla, M. J., Ruiz‐Moyano, S., Córdoba, M. D. G., Villalobos, M. C., Casquete, R., & Hernández, A. (2016) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2016.10.033 · Cited by 65 · see citing works
Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm
Arnaouteli, S., Matoz-Fernandez, D. A., Porter, M., Kalamara, M., Abbott, J., MacPhee, C. E., Davidson, F. A., & Stanley‐Wall, N. R. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1903982116 · Cited by 65 · see citing works
Liu, P., Luo, L., & Long, C.-A. (2013) · Biological Control · doi:10.1016/j.biocontrol.2013.07.011 · Cited by 64 · see citing works
Wang, X., Glawe, D. A., Kramer, E., Weller, D. M., & Okubara, P. A. (2018) · Phytopathology · doi:10.1094/phyto-09-17-0306-r · Cited by 66 · see citing works
The ecology of killer yeasts: Interference competition in natural habitats
Boynton, P. J. (2019) · Yeast · doi:10.1002/yea.3398 · Cited by 58 · see citing works
Bioprotection strategies in winemaking
Gianvito, P. D., Englezos, V., Rantsiou, K., & Cocolin, L. (2022) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2022.109532 · Cited by 61 · see citing works
Kalia, A., & Parshad, V. R. (2013) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2011.649315 · Cited by 61 · see citing works
Türkel, S., Korukluoğlu, M., & Yavuz, M. (2014) · Biotechnology Research International · doi:10.1155/2014/397167 · Cited by 61 · see citing works
Aureobasidium pullulansas a biocontrol agent of postharvest pathogens of apples in Uruguay
Vero, S., Garmendia, G., González, M., Garat, M. F., & Wisniewski, M. (2009) · Biocontrol Science and Technology · doi:10.1080/09583150903277738 · Cited by 60 · see citing works
Öztekin, S., & Karbancıoğlu‐Güler, F. (2021) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2021.111634 · Cited by 58 · see citing works
The forgotten role of food cultures
Bourdichon, F., Arias‐Roth, E., Babuchowski, A., Buckle, A. E., Bello, F. D., Dubois, A., Fontana, A., Fritz, D., Kemperman, R., Laulund, S., et al. (2021) · FEMS Microbiology Letters · doi:10.1093/femsle/fnab085 · Cited by 56 · see citing works
What are the 100 most cited fungal genera?
Bhunjun, C. S., Chen, Y. J., Phukhamsakda, C., Boekhout, T., Groenewald, J. Z., McKenzi, E. H. C., Francisco, E. C., Frisvad, J. C., Groenewald, M., Hurdeal, V. G., et al. (2024) · Studies in Mycology · doi:10.3114/sim.2024.108.01 · Cited by 57 · see citing works
Kántor, A., Huťková, J., Petrová, J., Hleba, L., & Kačániová, M. (2015) · Journal of Microbiology Biotechnology and Food Sciences · doi:10.15414/jmbfs.2015/16.5.3.282-285 · Cited by 56 · see citing works
Wang, D., Zhan, Y., Cai, D., Li, X., Wang, Q., & Chen, S. (2018) · Applied and Environmental Microbiology · doi:10.1128/aem.00262-18 · Cited by 55 · see citing works
Zeng, J., Xu, T., Cao, L., Tong, C., Zhang, X., Luo, D., Han, S., Pei, P., Fu, W., Yan, J., et al. (2018) · Microbial Ecology · doi:10.1007/s00248-018-1189-x · Cited by 55 · see citing works
Oleaginous yeasts: Biodiversity and cultivation
Poontawee, R., Lorliam, W., Polburee, P., & Limtong, S. (2022) · Fungal Biology Reviews · doi:10.1016/j.fbr.2022.11.003 · Cited by 54 · see citing works
Potential Role of Yeast Strains Isolated from Grapes in the Production of Taurasi DOCG
Aponte, M., & Blaiotta, G. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00809 · Cited by 53 · see citing works
Exploring yeast‐based microbial interactions: The next frontier in postharvest biocontrol
Ağırman, B., Çarşanba, E., Settanni, L., & Erten, H. (2023) · Yeast · doi:10.1002/yea.3895 · Cited by 54 · see citing works
Lachance, M., Dobson, J., Wijayanayaka, D. N., & Smith, A. M. E. (2009) · Antonie van Leeuwenhoek · doi:10.1007/s10482-009-9399-3 · Cited by 50 · see citing works
Yang, H., Wang, L., Li, S., Gao, X., Wu, N., Zhao, Y., & Sun, W. (2020) · Biological Control · doi:10.1016/j.biocontrol.2020.104406 · Cited by 49 · see citing works
Biological control of mycotoxin-producing molds
de Medeiros, F. H. V., Martins, S. J., Zucchi, T. D., de Melo, I. S., Batista, L. R., & Machado, J. D. C. (2012) · Ciência e Agrotecnologia · doi:10.1590/s1413-70542012000500001 · Cited by 49 · see citing works
Microbial Resources as a Tool for Enhancing Sustainability in Winemaking
Nardi, T. (2020) · Microorganisms · doi:10.3390/microorganisms8040507 · Cited by 49 · see citing works
Agarbati, A., Canonico, L., Pecci, T., Romanazzi, G., Ciani, M., & Comitini, F. (2022) · Microorganisms · doi:10.3390/microorganisms10020200 · Cited by 49 · see citing works
Strategies to control post-harvest diseases of table grape: a review
Sonker, N., Pandey, A. K., & Singh, P. (2016) · Journal of Wine Research · doi:10.1080/09571264.2016.1151407 · Cited by 47 · see citing works
Antagonistic interaction between yeasts and lactic acid bacteria of oenological relevance
Mendoza, L. M., de Nadra, M. C. M., & Farı́as, M. E. (2010) · Food Research International · doi:10.1016/j.foodres.2010.05.017 · Cited by 46 · see citing works
Kurtzman, C. P., Robnett, C. J., Basehoar-Powers, E., & Ward, T. J. (2018) · Antonie van Leeuwenhoek · doi:10.1007/s10482-018-1095-8 · Cited by 44 · see citing works
Bio-protection in oenology by Metschnikowia pulcherrima: from field results to scientific inquiry
Puyo, M., Simonin, S., Bach, B., Klein, G., Alexandre, H., & Tourdot‐Maréchal, R. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1252973 · Cited by 48 · see citing works
Randazzo, P., Aubert-Frambourg, A., Guillot, A., & Auger, S. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0807-3 · Cited by 43 · see citing works
Identification and High-level Production of Pulcherrimin in Bacillus licheniformis DW2
Li, X., Wang, D., Cai, D., Zhan, Y., Wang, Q., & Chen, S. (2017) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-017-2500-x · Cited by 43 · see citing works
Abeln, F., Fan, J., Budarin, V. L., Briers, H. K., Parsons, S., Allen, M. J., Henk, D. A., Clark, J. H., & Chuck, C. J. (2019) · Algal Research · doi:10.1016/j.algal.2019.101411 · Cited by 43 · see citing works
Abeln, F., & Chuck, C. J. (2019) · Biotechnology and Bioengineering · doi:10.1002/bit.27141 · Cited by 43 · see citing works
Yuan, S., Yong, X., Zhao, T., Li, Y., & Liu, J. (2020) · Molecules · doi:10.3390/molecules25235611 · Cited by 42 · see citing works
Recent advances in research on biocontrol of postharvest fungal decay in apples
Leng, J., Yu, L., Dai, Y. Q., Leng, Y., Wang, C., Chen, Z., Wisniewski, M., Wu, X., Liu, J., & Sui, Y. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2080638 · Cited by 42 · see citing works
Yurkov, A. M., Krüger, D., Begerow, D., Arnold, N., & Tarkka, M. T. (2011) · Microbial Ecology · doi:10.1007/s00248-011-9923-7 · Cited by 41 · see citing works
Biological control of green mould on mandarin fruit through the combined use of antagonistic yeasts
Öztekin, S., & Karbancıoğlu‐Güler, F. (2023) · Biological Control · doi:10.1016/j.biocontrol.2023.105186 · Cited by 42 · see citing works
Biological Activity of Pulcherrimin from the Meschnikowia pulcherrima Clade
Kręgiel, D., Nowacka, M., Rygała, A., & Vadkertiová, R. (2022) · Molecules · doi:10.3390/molecules27061855 · Cited by 40 · see citing works
Murgier, J., Everaerts, C., Farine, J., & Ferveur, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-45140-z · Cited by 39 · see citing works
Biasi, A., Zhimo, V. Y., Kumar, A., Abdelfattah, A., Salim, S., Feygenberg, O., Wisniewski, M., & Droby, S. (2021) · Horticulturae · doi:10.3390/horticulturae7100360 · Cited by 42 · see citing works
Begerow, D., Kemler, M., Feige, A., & Yurkov, A. M. (2017) · Springer eBooks · doi:10.1007/978-3-319-61575-2_7 · Cited by 38 · see citing works
Yeasts in Agricultural and Managed Soils
Vadkertiová, R., Dudášová, H., & Balaščáková, M. (2017) · Yeasts in Natural Ecosystems: Diversity · doi:10.1007/978-3-319-62683-3_4 · Cited by 38 · see citing works
Sirén, K., Mak, S. S. T., Melkonian, C., Carøe, C., Swiegers, J. H., Douwe Molenaar, B., Fischer, U., & Gilbert, M. T. P. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00697 · Cited by 36 · see citing works
Sipiczki, M., Pfliegler, W. P., & Holb, I. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067384 · Cited by 37 · see citing works
Self-citationSipiczki, M. (2023) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2023.110360 · Cited by 36 · see citing works
Self-citationSipiczki, M., Horváth, E., & Pfliegler, W. P. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01193 · Cited by 36 · see citing works
Self-citationWang, S., Zhang, H., Qi, T., Deng, L., Yi, L., & Zeng, K. (2021) · Food Microbiology · doi:10.1016/j.fm.2021.103888 · Cited by 36 · see citing works
- Authors
- Sipiczki, M.
- Affiliations
- University of Debrecen (HU)
- Corresponding author
- Sipiczki, Matthias
- ORCID
- Sipiczki, Matthias
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2006-10
- Volume
- 72
- Issue
- 10
- Pages
- 6716-6724
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- PMC
- PMC1610289
- OpenAlex
- W2168624838
- Cited by
- 291
- References
- 57
- Citations by year
- 2026: 15 · 2025: 26 · 2024: 19 · 2023: 29 · 2022: 19 · 2021: 21 · 2020: 24 · 2019: 29 · 2018: 20 · 2017: 19 · 2016: 16 · 2015: 7 · 2014: 10 · 2013: 11 · 2012: 7
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Applied and Environmental Microbiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- University of Debrecen Electronic Archive (University of Debrecen) (submittedVersion, other-oa)
- Funders
- Nemzeti Kutatási és Technológiai Hivatal
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Fermentation and Sensory Analysis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Keywords
- Metschnikowia, Botrytis, microbial antagonism, iron depletion, pigment production, antifungal activity, antibacterial activity, conidial germination inhibition, tropolone, yeast isolates
- MeSH terms
- Iron Deficiencies, Antibiosis, Bacteria, Saccharomycetales, Molecular Sequence Data, Siderophores, Ecosystem, Botrytis, Vitis
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