Impact of feed efficiency and diet on adaptive variations in the bacterial community in the rumen fluid of cattle
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Limited knowledge of the structure and activities of the ruminal bacterial community prevents the understanding of the effect of population dynamics on functional bacterial groups and on host productivity. This study aimed to identify particular bacteria associated with host feed efficiency in steers with differing diets and residual feed intake (RFI) using culture-independent methods: PCR-denaturing gradient gel electrophoresis (DGGE) and quantitative real-time PCR analysis. PCR-DGGE profiles were generated from the ruminal fluid of 55 steers fed a low-energy-density diet and then switched to a high-energy-density diet. Bacterial profile comparisons by multivariate statistical analysis showed a trend only for RFI-related clusters on the high-energy diet. When steers (n = 19) belonging to the same RFI group under both diets were used to identify specific bacterial phylotypes related to feed efficiency traits, correlations were detected between dry matter intake, average daily gain, and copy numbers of the 16S rRNA gene of Succinivibrio sp. in low-RFI (efficient) steers, whereas correlations between Robinsoniella sp. and RFI (P < 0.05) were observed for high-RFI (inefficient) animals. Eubacterium sp. differed significantly (P < 0.05) between RFI groups that were only on the high-energy diet. Our work provides a comprehensive framework to understand how particular bacterial phylotypes contribute to differences in feed efficiency and ultimately influence host productivity, which may either depend on or be independent from diet factors.
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Positive correlations between Eubacterium sp. and reduced feed efficiency were reported.
“Positive correlations between Eubacterium sp. and reduced feed efficiency were also reported by Hernandez-Sanabria et al. (2012).”
From Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future (2018) · cites this paper as Hernandez-Sanabria et al., 2012
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- Authors
- Hernandez-Sanabria, E., Goonewardene, L. A., Wang, Z., Durunna, O. N., Moore, S. S., & Guan, L. L.
- Affiliations
- Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
- University of Alberta (CA)
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2012-02-15
- Volume
- 78
- Issue
- 4
- Pages
- 1203-1214
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- PMC
- PMC3273029
- OpenAlex
- W1974262472
- Cited by
- 207
- References
- 55
- Citations by year
- 2026: 4 · 2025: 14 · 2024: 15 · 2023: 13 · 2022: 23 · 2021: 17 · 2020: 19 · 2019: 15 · 2018: 17 · 2017: 17 · 2016: 17 · 2015: 17 · 2014: 11 · 2013: 4 · 2012: 4
- FWCI
- 11.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Applied and Environmental Microbiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Ruminant Nutrition and Digestive Physiology
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- residual feed intake, feed efficiency, steers, Succinivibrio, Eubacterium, 16S rRNA gene, dry matter intake, average daily gain, cattle
- MeSH terms
- Animals, Bacteria, Cattle, Diet, DNA, Bacterial, DNA, Ribosomal, RNA, Ribosomal, 16S, Rumen, Cluster Analysis, DNA Fingerprinting, Metagenome, Biota, Bacterial Load, Denaturing Gradient Gel Electrophoresis, Real-Time Polymerase Chain Reaction
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