The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Versatility of Aminoglycosides and Prospects for Their Future
Open accessAbstract
SUMMARY: Aminoglycoside antibiotics have had a major impact on our ability to treat bacterial infections for the past half century. Whereas the interest in these versatile antibiotics continues to be high, their clinical utility has been compromised by widespread instances of resistance. The multitude of mechanisms of resistance is disconcerting but also illuminates how nature can manifest resistance when bacteria are confronted by antibiotics. This article reviews the most recent knowledge about the mechanisms of aminoglycoside action and the mechanisms of resistance to these antibiotics.
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Cites
Structure of the 30S ribosomal subunit
Wimberly, B. T., Brodersen, D. E., Clemons, W. M., Morgan-Warren, R. J., Carter, A. P., Vonrhein, C., Hartsch, T., & Ramakrishnan, V. (2000) · Nature · doi:10.1038/35030006 · Cited by 2,035
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
Schluenzen, F., Tocilj, A., Zarivach, R., Harms, J., Gluehmann, M., Janell, D., Bashan, A., Bartels, H., Agmon, I., Franceschi, F., et al. (2000) · Cell · doi:10.1016/s0092-8674(00)00084-2 · Cited by 979
Brodersen, D. E., Clemons, W. M., Carter, A. P., Morgan-Warren, R. J., Wimberly, B. T., & Ramakrishnan, V. (2000) · Cell · doi:10.1016/s0092-8674(00)00216-6 · Cited by 950 · cited 1×
“and hygromycin B have been solved (12, 27, 45, 117, 257, 306, 315).”
Hochhut, B., Lotfi, Y., Mazel, D., Faruque, S. M., Woodgate, R., & Waldor, M. K. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.11.2991-3000.2001 · Cited by 318
Beaber, J. W., Hochhut, B., & Waldor, M. K. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.15.4259-4269.2002 · Cited by 248
Boyd, D., Cloeckaert, A., Chaslus-Dancla, E., & Mulvey, M. R. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1714-1722.2002 · Cited by 209 · cited 6×
“I genes have been identified frequently among various clinical isolates of Enterobacteriaceae (26, 165, 182, 253, 313), Pseudomonas aeruginosa (207), and Vibrio cholerae (66–68, 84).”
BackgroundInfluentialDetection of a Streptomycin/Spectinomycin Adenylyltransferase Gene ( aadA ) in Enterococcus faecalis
Clark, N. C., Olsvik, Ø., Swenson, J. M., Spiegel, C. A., & Tenover, F. C. (1999) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.43.1.157 · Cited by 202
SUNDIN, G. W., & BENDER, C. L. (1996) · Molecular Ecology · doi:10.1111/j.1365-294x.1996.tb00299.x · Cited by 195
Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies
Schiffelers, R. (2001) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/48.3.333 · Cited by 163
Dalsgaard, A., Forslund, A., Serichantalergs, O., & Sandvang, D. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.5.1315-1321.2000 · Cited by 118
Cited by
Metabolite-enabled eradication of bacterial persisters by aminoglycosides
Allison, K. R., Brynildsen, M. P., & Collins, J. J. (2011) · Nature · doi:10.1038/nature10069 · Cited by 1,025
Pseudomonas aeruginosa – a phenomenon of bacterial resistance
Strateva, T., & Yordanov, D. (2009) · Journal of Medical Microbiology · doi:10.1099/jmm.0.009142-0 · Cited by 803
How to manage Pseudomonas aeruginosa infections
Bassetti, M., Vena, A., Croxatto, A., Righi, E., & Guery, B. (2018) · Drugs in Context · doi:10.7573/dic.212527 · Cited by 746
Cell Death from Antibiotics Without the Involvement of Reactive Oxygen Species
Liu, Y., & Imlay, J. A. (2013) · Science · doi:10.1126/science.1232751 · Cited by 593
Uncultured soil bacteria are a reservoir of new antibiotic resistance genes
Riesenfeld, C. S., Goodman, R. M., & Handelsman, J. (2004) · Environmental Microbiology · doi:10.1111/j.1462-2920.2004.00664.x · Cited by 527
Metadata
- Authors
- Vakulenko, S. B., & Mobashery, S.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2003-07
- Volume
- 16
- Issue
- 3
- Pages
- 430-450
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2110424949
- Cited by
- 643
- References
- 11
- FWCI
- 8.06
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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