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The Human Oral Microbiome
Open accessAbstract
The human oral cavity contains a number of different habitats, including the teeth, gingival sulcus, tongue, cheeks, hard and soft palates, and tonsils, which are colonized by bacteria. The oral microbiome is comprised of over 600 prevalent taxa at the species level, with distinct subsets predominating at different habitats. The oral microbiome has been extensively characterized by cultivation and culture-independent molecular methods such as 16S rRNA cloning. Unfortunately, the vast majority of unnamed oral taxa are referenced by clone numbers or 16S rRNA GenBank accession numbers, often without taxonomic anchors. The first aim of this research was to collect 16S rRNA gene sequences into a curated phylogeny-based database, the Human Oral Microbiome Database (HOMD), and make it web accessible ( www.homd.org ). The HOMD includes 619 taxa in 13 phyla, as follows: Actinobacteria , Bacteroidetes , Chlamydiae , Chloroflexi , Euryarchaeota , Firmicutes , Fusobacteria , Proteobacteria , Spirochaetes , SR1, Synergistetes , Tenericutes , and TM7. The second aim was to analyze 36,043 16S rRNA gene clones isolated from studies of the oral microbiota to determine the relative abundance of taxa and identify novel candidate taxa. The analysis identified 1,179 taxa, of which 24% were named, 8% were cultivated but unnamed, and 68% were uncultivated phylotypes. Upon validation, 434 novel, nonsingleton taxa will be added to the HOMD. The number of taxa needed to account for 90%, 95%, or 99% of the clones examined is 259, 413, and 875, respectively. The HOMD is the first curated description of a human-associated microbiome and provides tools for use in understanding the role of the microbiome in health and disease.
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“It is estimated that about 50% of oral bacterial species are resistant to cultivation (Dewhirst et al., 2010)”
From Microbial colonisation associated with conventional and self-ligating brackets: a systematic review (2022) · cites this paper as Dewhirst et al., 2010
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In the citing paper
“These species are known to play roles in dental biofilm maturation and oral inflammatory conditions [35,36].”
From Severity-dependent alterations in oral microbiota and antibiotic resistance in children with dental fluorosis (2026) · cites this paper as [36]
Experimental — accuracy not yet measuredIn the citing paper
“Other core members with greater than 1% abundance across at least 80% of samples from 1 or more sites, included those from the family Pasteurellaceae, those from the genera Gemella, Veillonella, Prevotella, Fusobacterium, Porphyromonas, Neisseria, Capnocytophaga, Corynebacterium, and Actinomyces, and those from the orders Lactobacillales and Lachnospiraceae.160”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [160]
In the citing paper
“Moreover, the Human Microbiome Project found that the main genus among intraoral sites, at greater than 10% abundance and present in more than 75% of samples, was Streptococcus, specifically Streptococcus oralis, S mitis, and Streptococcus peroris.”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [160]
In the citing paper
“The oral cavity houses the second largest microbiota in the human body and can include bacteria, fungi, viruses, and archaea (Dewhirst et al., 2010).”
From Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection (2020) · cites this paper as Dewhirst et al., 2010
In the citing paper
“Most of above mentioned microbiota can be found in human oral cavity (Dewhirst et al., 2010)”
From Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection (2020) · cites this paper as Dewhirst et al., 2010
In the citing paper
“Culture-independent sequencing of the bacterial 16S ribosome has suggested an estimated 50–100 billion bacteria in the mouth, comprised of nearly 700 identified bacterial species[170,171].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [171]
In the citing paper
“Up to 80% of oral bacteria are dominated by about 200 species in the Phyla Firmicutes (esp. Streptococcus, Veillonella, Granulicatella, Gemella spp.) and Proteobacteria (esp. Neisseria, Haemophilus spp.), with contributions from Bacteroidetes, Actinobacteria and Fusobacteria totaling upwards of 95% of all identified oral microbiota (Figure 2)[171–177].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [171]
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Citations
Cites
The neighbor-joining method: a new method for reconstructing phylogenetic trees.
Saitou, N., & Nei, M. (1987) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040454 · Cited by 59,959
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
Tamura, K., Dudley, J. T., Nei, M., & Kumar, S. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm092 · Cited by 28,734
Bergey's Manual of Systematic Bacteriology
(1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-112-5-391_3 · Cited by 15,633
Evolution of Protein Molecules
JUKES, T. H., & CANTOR, C. R. (1969) · Mammalian Protein Metabolism · doi:10.1016/b978-1-4832-3211-9.50009-7 · Cited by 11,032
Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
DeSantis, T. Z., Hugenholtz, P., Larsen, N., Rojas, M., Brodie, E. L., Keller, K., Huber, T., Dalevi, D., Hu, P., & Andersen, G. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.03006-05 · Cited by 10,891
Bacterial biofilms: from the Natural environment to infectious diseases
Hall‐Stoodley, L., Costerton, J. W., & Stoodley, P. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro821 · Cited by 7,133
Turnbaugh, P. J., Ley, R. E., Hamady, M., Fraser-Liggett, C. M., Knight, R., & Gordon, J. I. (2007) · Nature · doi:10.1038/nature06244 · Cited by 6,091
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
Cole, J. R., Wang, Q., Cardenas, E., Fish, J., Chai, B., Farris, R. J., Kulam-Syed-Mohideen, A. S., McGarrell, D. M., Marsh, T. L., Garrity, G. M., et al. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn879 · Cited by 4,873
(1964) · Elsevier eBooks · doi:10.1016/b978-1-4832-3210-2.50006-6 · Cited by 3,130
Defining the normal bacterial flora of the oral cavity
Aas, J. A., Paster, B. J., Stokes, L. N., Olsen, I., & Dewhirst, F. E. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.11.5721-5732.2005 · Cited by 3,092
Self-citation
Cited by
Sorted by citations
Items 901–1,000 of 1,014
Predicting oral malodour based on the microbiota in saliva samples using a deep learning approach
Nakano, Y., Suzuki, N., & Kuwata, F. (2018) · BMC Oral Health · doi:10.1186/s12903-018-0591-6 · Cited by 47
Spatial Design of Polymicrobial Oral Biofilm in Its Native Disease State
Kim, D.-M., & Koo, H. (2020) · Journal of Dental Research · doi:10.1177/0022034520909313 · Cited by 46
Oral bacterial diversity is inversely correlated with mucosal inflammation.
Hijazi, K., Morrison, R. W., Mukhopadhya, I., Martin, B. D., Gemmell, M. R., Shaw, S., & Santoro, F. (2020) · Oral Diseases · doi:10.1111/odi.13420 · Cited by 44
Béchon, N., Jiménez‐Fernández, A., Witwinowski, J., Bierque, E., Taïb, N., Cokelaer, T., Ma, L., Ghigo, J., Gribaldo, S., & Beloin, C. (2020) · Journal of Bacteriology · doi:10.1128/jb.00461-20 · Cited by 46
Grydaki, N., Colbeck, I., Mendes, L., Eleftheriadis, K., & Whitby, C. B. (2020) · Environment International · doi:10.1016/j.envint.2020.106186 · Cited by 46
González, E., Brereton, N. J. B., Li, C., Leyva, L. L., Solomons, N. W., Agellon, L. B., Scott, M. E., & Koski, K. G. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.557180 · Cited by 50
Takenaka, S., Sotozono, M., Ohkura, N., & Noiri, Y. (2022) · Antibiotics · doi:10.3390/antibiotics11060727 · Cited by 52
Nadkarni, M. A., Browne, G. V., Chhour, K.-L., Byun, R., Nguyen, K.-A. T., Chapple, C. C., Jacques, N. A., & Hunter, N. (2012) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-012-1651-5 · Cited by 46
Luo, T., Srinivasan, U., Ramadugu, K., Shedden, K. A., Neiswanger, K., Trumble, E., Li, J. J., McNeil, D. W., Crout, R. J., Weyant, R. J., et al. (2016) · Applied and Environmental Microbiology · doi:10.1128/aem.01132-16 · Cited by 45
The oral microbiome, nitric oxide and exercise performance
Bryan, N. S., Burleigh, M. C., & Easton, C. (2022) · Nitric Oxide · doi:10.1016/j.niox.2022.05.004 · Cited by 46
End stage renal disease as a modifier of the periodontal microbiome
Araújo, M. V. F., Hong, B., Fava, P., Khan, S., Burleson, J. A., Fares, G., Samson, W., Strausbaugh, L. D., Diaz, P. I., & Ioannidou, E. (2015) · BMC Nephrology · doi:10.1186/s12882-015-0081-x · Cited by 44
Chung, M., Zhao, N., Meier, R. L., Koestler, D. C., Wu, G. G., del Castillo, E., Paster, B. J., Charpentier, K. P., Izard, J., Kelsey, K. T., et al. (2021) · Journal of Oral Microbiology · doi:10.1080/20002297.2021.1887680 · Cited by 46
Self-citationNext-Generation Examination, Diagnosis, and Personalized Medicine in Periodontal Disease
Kikuchi, T., Hayashi, J., & Mitani, A. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12101743 · Cited by 48
In Vivo Biofilm Formation on Novel PEEK, Titanium, and Zirconia Implant Abutment Materials
Wiessner, A., Wassmann, T., Wiessner, J. M., Schubert, A., Wiechens, B., Hampe, T., & Bürgers, R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021779 · Cited by 48
Tagg, J. R., Harold, L. K., Jain, R., & Hale, J. D. F. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1161155 · Cited by 51
Sobstyl, A., Chałupnik, A., Mertowska, P., & Grywalska, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310920 · Cited by 46
Schillinger, C., Petrich, A., Lux, R., Riep, B., Kikhney, J., Friedmann, A., Wolinsky, L. E., Göbel, U. B., Daims, H., & Moter, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037583 · Cited by 48
Comparative analysis of oral treponemes associated with periodontal health and disease
You, M., Mo, S., Leung, W. K., & Watt, R. M. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-174 · Cited by 45
Ibarz-Pavón, A. B., MacLennan, J. M., Andrews, N., Gray, S. J., Urwin, R., Clarke, S. C., Walker, A. M., Evans, M. R., Kroll, J. S., Neal, K. R., et al. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir466 · Cited by 45
RevEcoR: an R package for the reverse ecology analysis of microbiomes
Cao, Y., Wang, Y., Zheng, X., Li, F., & Bo, X. (2016) · BMC Bioinformatics · doi:10.1186/s12859-016-1088-4 · Cited by 45
Slavkin, H. C. (2017) · Journal of Dental Education · doi:10.21815/jde.017.041 · Cited by 45
Parker, M., Onetto, C. A., Hixson, J. L., Bilogrevic, E., Schueth, L., Pisaniello, L., Borneman, A. R., Herderich, M. J., Lopes, M. D. B., & Francis, I. L. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b05450 · Cited by 45
Schwarz, S. R., Hirsch, S., Hiergeist, A., Kirschneck, C., Muehler, D., Hiller, K., Maisch, T., Al‐Ahmad, A., Gessner, A., Buchalla, W., et al. (2020) · Clinical Oral Investigations · doi:10.1007/s00784-020-03613-w · Cited by 45
A potential therapeutic strategy for prostatic disease by targeting the oral microbiome
Fang, C., Wu, L., Zhu, C., Xie, W., Hu, H., & Zeng, X. (2020) · Medicinal Research Reviews · doi:10.1002/med.21778 · Cited by 47
Salivary Biomarkers in Periodontitis Patients: A Pilot Study
Reddahi, S., Bouziane, A., Rida, S., Tligui, H., & Ennibi, O. (2022) · International Journal of Dentistry · doi:10.1155/2022/3664516 · Cited by 44
Shi, J., Yang, Y., Xie, H., Wang, X., Wu, J., Long, J., Courtney, R., Shu, X., Zheng, W., Blot, W. J., et al. (2021) · Cancer Causes & Control · doi:10.1007/s10552-021-01490-6 · Cited by 44
Pathophysiology and immunogenetics of celiac disease
Aboulaghras, S., Piancatelli, D., Oumhani, K., Balahbib, A., Bouyahya, A., & Taghzouti, K. (2022) · Clinica Chimica Acta · doi:10.1016/j.cca.2022.01.022 · Cited by 46
Association of the Microbiota and Pancreatic Cancer: Opportunities and Limitations
Chen, Z., Zhang, S., Dong, S., Xu, H. M., & Zhou, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.844401 · Cited by 45
Site Specialization of Human Oral Veillonella Species
Giacomini, J. J., Torres‐Morales, J., Dewhirst, F. E., Borisy, G. G., & Welch, J. L. M. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04042-22 · Cited by 47
Self-citationpH-Responsive Biomaterials for the Treatment of Dental Caries—A Focussed and Critical Review
He, Y., Vasilev, K. A., & Zilm, P. S. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15071837 · Cited by 50
Aciduric microbiota and mutans streptococci in severe and recurrent severe early childhood caries.
Hughes, C. V., Dahlan, M., Papadopolou, E., Loo, C. Y., Pradhan, N., Lu, S. C., Mathney, J. M. J., Bravoco, A., Kent, R., & Tanner, A. C. R. (2012) · PubMed · Cited by 44
Self-citationBeta‐diversity metrics of the upper digestive tract microbiome are associated with body mass index
Lin, S., Freedman, N. D., Shi, J., Gail, M. H., Vogtmann, E., Yu, G., Klepac‐Ceraj, V., Paster, B. J., Dye, B. A., Wang, G., et al. (2015) · Obesity · doi:10.1002/oby.21020 · Cited by 48
Self-citationOily sludge stimulates microbial activity and changes microbial structure in a landfarming soil
de Quadros, P. D., Cerqueira, V. S., Cazarolli, J. C., Peralba, M. D. C. R., Camargo, F. A. D. O., Giongo, A., & Bento, F. M. (2016) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2016.07.018 · Cited by 44
Metabolic network percolation quantifies biosynthetic capabilities across the human oral microbiome
Bernstein, D. B., Dewhirst, F. E., & Segrè, D. (2019) · eLife · doi:10.7554/elife.39733 · Cited by 44
Self-citationJung, J.-I., Baek, S.-M., Nguyen, T. H., Kim, J., Kang, C.-H., Kim, S., & Imm, J. (2021) · Molecules · doi:10.3390/molecules26030733 · Cited by 46
The Effects of E-Cigarette Aerosol on Oral Cavity Cells and Tissues: A Narrative Review
Szumilas, P., Wilk, A., Szumilas, K., & Karakiewicz, B. (2022) · Toxics · doi:10.3390/toxics10020074 · Cited by 43
Comparative Analysis of Primers Used for 16S rRNA Gene Sequencing in Oral Microbiome Studies
Na, H. S., Song, Y., Yu, Y., & Chung, J. (2023) · Methods and Protocols · doi:10.3390/mps6040071 · Cited by 48
Development and pyrosequencing analysis of an in-vitro oral biofilm model
Kistler, J. O., Pesaro, M., & Wade, W. G. (2015) · BMC Microbiology · doi:10.1186/s12866-015-0364-1 · Cited by 43
Self-citationCharacterisation of the human oral microbiome
Wade, W. G. (2013) · Journal of Oral Biosciences · doi:10.1016/j.job.2013.06.001 · Cited by 43
Self-citationPrevalence and diversity of S ynergistetes taxa in periodontal health and disease
You, M., Mo, S., Watt, R. M., & Leung, W. K. (2012) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2012.01516.x · Cited by 43
Can oral pathogens influence allergic disease?
Arbes, S. J., & Matsui, E. C. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.03.023 · Cited by 43
Duran-Pinedo, A. E., Baker, V. D., & Frias‐Lopez, J. (2014) · Infection and Immunity · doi:10.1128/iai.01976-14 · Cited by 43
Zenobia, C., Hastürk, H., Nguyen, D., Dyke, T. E. V., Kantarcı, A., & Darveau, R. P. (2013) · Infection and Immunity · doi:10.1128/iai.01136-13 · Cited by 43
Cultivation strategies for growth of uncultivated bacteria
Vartoukian, S. R. (2016) · Journal of Oral Biosciences · doi:10.1016/j.job.2016.08.001 · Cited by 42
Cabral, D. J., Wurster, J. I., Flokas, M. E., Alevizakos, M., Zabat, M. A., Korry, B. J., Rowan-Nash, A. D., Sano, W. H., Andreatos, N., Ducharme, R., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-11427-2 · Cited by 45
Lung cancer: a new frontier for microbiome research and clinical translation
Mur, L. A. J., Huws, S., Cameron, S. J. S., Lewis, P. D., & Lewis, K. E. (2018) · ecancermedicalscience · doi:10.3332/ecancer.2018.866 · Cited by 42
Dental caries are positively associated with periodontal disease severity
Durand, R., Roufegarinejad, A., Chandad, F., Rompre, P. H., Voyer, R., Michalowicz, B. S., & Emami, E. (2019) · Clinical Oral Investigations · doi:10.1007/s00784-019-02810-6 · Cited by 44
Alterations to the Lung Microbiome in Idiopathic Pulmonary Fibrosis Patients
Tong, X., Su, F., Xu, X., Xu, H., Yang, T., Xu, Q., Dai, H., Huang, K., Zou, L., Zhang, W., et al. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00149 · Cited by 42
Khemwong, T., Kobayashi, H., Ikeda, Y., Matsuura, T., Sudo, T., Kano, C., Mikami, R., & Izumi, Y. (2019) · PLoS ONE · doi:10.1371/journal.pone.0218266 · Cited by 43
Diaz, P. I., Hong, B., Dupuy, A. K., Choquette, L. E., Thompson, A. K., Salner, A., Schauer, P. K., Hegde, U. P., Burleson, J. A., Strausbaugh, L. D., et al. (2019) · Journal of Fungi · doi:10.3390/jof5020049 · Cited by 44
Exploring the putative interactions between chronic kidney disease and chronic periodontitis
Hickey, N. A., Shalamanova, L., Whitehead, K. A., Dempsey‐Hibbert, N., Gast, C., & Taylor, R. L. (2020) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2020.1724872 · Cited by 43
Acetaldehyde production by Rothia mucilaginosa isolates from patients with oral leukoplakia
Amer, A., Whelan, A., Al-Hebshi, N. N., Healy, C. M., & Moran, G. P. (2020) · Journal of Oral Microbiology · doi:10.1080/20002297.2020.1743066 · Cited by 43
Zero‐inflated Poisson factor model with application to microbiome read counts
Xu, T., Demmer, R. T., & Li, G. (2020) · Biometrics · doi:10.1111/biom.13272 · Cited by 43
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Tang, B., Gong, T., Cui, Y., Wang, L., He, C. S., Lu, M., Chen, J., Jing, M., Zhang, A., & Li, Y. (2020) · International Journal of Oral Science · doi:10.1038/s41368-020-0079-5 · Cited by 45
The evolutionary history of the human oral microbiota and its implications for modern health
Weyrich, L. S. (2020) · Periodontology 2000 · doi:10.1111/prd.12353 · Cited by 45
Bellando-Randone, S., Russo, E., Venerito, V., Matucci‐Cerinic, M., Iannone, F., Tangaro, S., & Amedei, A. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11070625 · Cited by 47
Contaldo, M., Lucchese, A., Romano, A., della Vella, F., Stasio, D. D., Serpico, R., & Petruzzi, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179251 · Cited by 43
Microbial Evasion of IgA Functions
Kilian, M., & Russell, M. W. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-415847-4.00022-7 · Cited by 43
Valen, H., & Scheie, A. A. (2018) · European Journal of Oral Sciences · doi:10.1111/eos.12425 · Cited by 42
The importance of the microbiome in epidemiologic research
Hanson, B., & Weinstock, G. M. (2016) · Annals of Epidemiology · doi:10.1016/j.annepidem.2016.03.008 · Cited by 44
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Lin, C., Chen, Y., Ho, H.-H., Kuo, Y., Lin, W., Chen, J., Lin, J., Liu, C., Lin, C.-H., Yeh, Y., et al. (2022) · Aging · doi:10.18632/aging.203923 · Cited by 45
Site‐tropism of streptococci in the oral microbiome
McLean, A. R., Torres‐Morales, J., Dewhirst, F. E., Borisy, G. G., & Welch, J. L. M. (2022) · Molecular Oral Microbiology · doi:10.1111/omi.12387 · Cited by 44
Self-citationCláudia-Ferreira, A., Barbosa, D. J., Saegeman, V., Fernández-Rodríguez, A., Dinis‐Oliveira, R. J., Freitas, A. R., & on behalf of the ESCMID Study Group of Forensic and Post-Mortem Microbiology (ESGFOR) (2023) · Microorganisms · doi:10.3390/microorganisms11102509 · Cited by 47
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Hong, S. J., Yang, B., Yoo, D. M., Kim, S., Choi, H. G., & Byun, S. (2021) · BMC Oral Health · doi:10.1186/s12903-021-01496-1 · Cited by 46
Presence of periodontal pathogenic bacteria in blood of patients with coronary artery disease
Corredor, Z., Suárez-Molina, A., Fong, C., Cifuentes-C, L., & Guauque-Olarte, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-05337-1 · Cited by 50
Souza, J. G. S., Costa, R. C., Sampaio, A. A., Abdo, V. L., NAGAY, B. E., Castro, N., Retamal‐Valdes, B., Shibli, J. A., Feres, M., Barão, V. A. R., et al. (2022) · iScience · doi:10.1016/j.isci.2022.103994 · Cited by 42
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Lin, X., Wang, Y., Ma, Z., Xie, M., Liu, Z., Cheng, J., Tian, Y., & Shi, H. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1141474 · Cited by 41
Syukri, D. M., Singh, S. K., Nwabor, O. F., Ontong, J. C., Dejyong, K., Sunghan, J., Dejyong, K., Lethongkam, S., & Voravuthikunchai, S. P. (2024) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-024-00335-3 · Cited by 43
Sizova, M. V., Muller, P. A., Stancyk, D., Panikov, N. S., Mandalakis, M., Hazen, A., Hohmann, T., Doerfert, S. N., Fowle, W. H., Earl, A. M., et al. (2014) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.060988-0 · Cited by 41
Immuno-Pathogenesis of Periodontal Disease: Current and Emerging Paradigms
Huang, N., & Gibson, F. C. (2014) · Current Oral Health Reports · doi:10.1007/s40496-014-0017-8 · Cited by 41
Deciphering the human microbiome using next-generation sequencing data and bioinformatics approaches
Kim, Y., Koh, I., & Rho, M. (2014) · Methods · doi:10.1016/j.ymeth.2014.10.022 · Cited by 44
Dassi, E., Ballarini, A., Covello, G., Quattrone, A., Jousson, O., Sanctis, V. D., Bertorelli, R., Denti, M. A., & Segata, N. (2014) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.03.024 · Cited by 41
Hanada, A., Kurogi, T., Giang, N. M., Yamada, T., Kamimoto, Y., Kiso, Y., & Hiraishi, A. (2014) · Microbes and Environments · doi:10.1264/jsme2.me14052 · Cited by 41
Cockburn, A., Dehlin, J. M., Ngan, T., Crout, R. J., Bošković, G., Denvir, J., Primerano, D. A., Plassman, B. L., Wu, B., & Cuff, C. F. (2012) · Investigative Genetics · doi:10.1186/2041-2223-3-19 · Cited by 41
Microbial profile of patients with periodontitis compared with healthy subjects.
Stîngu, C. S., Jentsch, H. F. R., Eick, S., Schaumann, R., Knöfler, G. U., & Rodloff, A. C. (2012) · PubMed · Cited by 41
Role of Microbes in Human Health
Kumar, A., & Chordia, N. (2017) · Applied Microbiology open access · doi:10.4172/2471-9315.1000131 · Cited by 45
Peters, B. A., McCullough, M. L., Purdue, M. P., Freedman, N. D., Um, C. Y., Gapstur, S. M., Hayes, R. B., & Ahn, J. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-18-0184 · Cited by 41
Johnson, L., Almeida-da-Silva, C. L. C., Takiya, C. M., Figliuolo, V. R., Rocha, G. M., Weissmüller, G., Scharfstein, J., Coutinho‐Silva, R., & Ojcius, D. M. (2018) · Biomedical Journal · doi:10.1016/j.bj.2018.05.001 · Cited by 41
Stenhagen, I. S. R., Valen, H. R., Dragland, I. S., & Kopperud, H. M. (2018) · European Journal Of Oral Sciences · doi:10.1111/eos.12584 · Cited by 41
Oral and Systemic Effects of Xylitol Consumption
Janket, S., Benwait, J., Isaac, P., Ackerson, L. K., & Meurman, J. H. (2019) · Caries Research · doi:10.1159/000499194 · Cited by 44
Microbiome of Odontogenic Abscesses
Böttger, S., Zechel-Gran, S., Schmermund, D., Streckbein, P., Wilbrand, J.-F., Knitschke, M., Pons‐Kühnemann, J., Hain, T., Weigel, M., Howaldt, H., et al. (2021) · Microorganisms · doi:10.3390/microorganisms9061307 · Cited by 41
Pultar, F., Hansen, M. E., Wolfrum, S., Böselt, L., Fróis-Martins, R., Bloch, S., Kravina, A. G., Pehlivanoglu, D., Schäffer, C., LeibundGut‐Landmann, S., et al. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.1c04825 · Cited by 40
Mun, L. S., Lum, S. W., Sze, G. K. Y., Yoong, C. H., Yung, K. C., Lok, L. K., & Gopinath, D. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18147224 · Cited by 41
Barbagallo, G., Santagati, M., Guni, A., Torrisi, P., Spitale, A., Stefani, S., Ferlito, S., & Nibali, L. (2021) · Clinical Oral Investigations · doi:10.1007/s00784-021-04253-4 · Cited by 43
Liu, Y., Li, Z., Qi, Y., Wen, X., & Zhang, L. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.795777 · Cited by 44
Cross Talk between Synthetic Food Colors (Azo Dyes), Oral Flora, and Cardiovascular Disorders
John, A., Yang, H., Muhammad, S., Khan, Z. I., Yu, H., Luqman, M., Tufail, M., Hussain, M. I., & Awan, M. U. F. (2022) · Applied Sciences · doi:10.3390/app12147084 · Cited by 41
Mao, S., Huang, C.-P., Lan, H., Lau, H.-G., Chiang, C., & Chen, Y. (2022) · Journal of Dental Sciences · doi:10.1016/j.jds.2022.07.001 · Cited by 43
Goldberg, B., Mongodin, E. F., Jones, C., Chung, M. T. M., Fraser, C. M., Tate, A. R., & Zeichner, S. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0131615 · Cited by 42
Oral‐gut bacterial profiles discriminate between periodontal health and diseases
Lourenço, T. G. B., de Oliveira, A. M., Chen, T., & Colombo, A. P. V. (2022) · Journal of Periodontal Research · doi:10.1111/jre.13059 · Cited by 42
Self-citationGios, E., Mosley, O. E., Weaver, L., Close, M. E., Daughney, C., & Handley, K. M. (2023) · ISME Communications · doi:10.1038/s43705-023-00223-x · Cited by 41
Dhami, M., Raj, K., & Singh, S. (2023) · Aging and Health Research · doi:10.1016/j.ahr.2023.100128 · Cited by 44
Oral health as a modifiable risk factor for cardiovascular diseases
Altamura, S., Pinto, R. D., Pietropaoli, D., & Ferri, C. (2023) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2023.03.003 · Cited by 43
Wu, Y., Lan, Y., Mao, J., Shen, J., Kang, T., & Xie, Z. (2023) · International Journal of Oral Science · doi:10.1038/s41368-023-00241-4 · Cited by 40
Nagakubo, D., & Kaibori, Y. (2023) · Microorganisms · doi:10.3390/microorganisms11092307 · Cited by 70
Metadata
- Authors
- Dewhirst, F. E., Chen, T., Izard, J., Paster, B. J., Tanner, A. C. R., Yu, W.-H., Lakshmanan, A., & Wade, W. G.
- Affiliations
- Harvard University (US)
- The Forsyth Institute (US)
- King's College London (GB)
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 2010-10
- Volume
- 192
- Issue
- 19
- Pages
- 5002-5017
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- PMC
- PMC2944498
- OpenAlex
- W2121748291
- Cited by
- 3,352
- References
- 75
- Citations by year
- 2026: 188 · 2025: 232 · 2024: 250 · 2023: 290 · 2022: 276 · 2021: 327 · 2020: 325 · 2019: 246 · 2018: 193 · 2017: 211 · 2016: 152 · 2015: 174 · 2014: 183 · 2013: 106 · 2012: 108
- FWCI
- 111.50
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Bacteriology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Lincoln (University of Nebraska) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- National Institute of Dental and Craniofacial Research (DE017106, DE-015847, U01DE016937, DE-016937, R01DE015847, R37DE016937, R21DE017106, R01DE016937)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- oral microbiota, 16S rRNA gene sequences, bacterial diversity, bacterial phylogeny, novel bacterial taxa, bacterial abundance
- MeSH terms
- Bacteria, Chlamydia, Humans, Molecular Sequence Data, Mouth, Phylogeny, RNA, Ribosomal, 16S, Spirochaetales, Proteobacteria, Actinobacteria, Chloroflexi, Bacteroidetes, Fusobacteria, Metagenome
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