Real-Time Analysis of Mucosal Flora in Patients with Inflammatory Bowel Disease in India
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Mucosa-associated bacterial flora from control individuals and inflammatory bowel disease (IBD) patients were evaluated by real-time analysis using 16S rRNA-based genus-specific primers. Our data show a clear delineation in concentration of bacteria between the predominating and subdominating genera under disease conditions, indicating that the subsets of bacteria participating in the pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) are likely to be different.
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This finding is in line with the suggestion that SRB are linked to an inflammatory state of the gut.
“This is in line with the suggestion that SRB are linked to an inflammatory state of the gut 41, 42.”
From The composition of the gut microbiota shapes the colon mucus barrier (2015) · cites this paper as [41]
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- Authors
- Verma, R., Verma, A. K., Ahuja, V., & Paul, J.
- Affiliations
- Jawaharlal Nehru University (IN)
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2010-11
- Volume
- 48
- Issue
- 11
- Pages
- 4279-4282
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- PMC
- PMC3020854
- OpenAlex
- W2161394655
- Cited by
- 124
- References
- 25
- Citations by year
- 2026: 4 · 2025: 1 · 2024: 10 · 2023: 16 · 2022: 10 · 2021: 11 · 2020: 11 · 2019: 8 · 2018: 8 · 2017: 7 · 2016: 8 · 2015: 11 · 2014: 7 · 2013: 6 · 2012: 5
- FWCI
- 2.16
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Microbiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Indian Council of Medical Research
- University Grants Commission
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- inflammatory bowel disease, ulcerative colitis, Crohn's disease, 16S rRNA gene, bacterial genera, gut microbiota, pathogenesis, India
- MeSH terms
- Adolescent, Adult, Aged, Bacteria, DNA, Bacterial, DNA, Ribosomal, Female, Humans, India, Intestinal Mucosa, Male, Middle Aged, RNA, Ribosomal, 16S, Inflammatory Bowel Diseases, Biodiversity, Metagenome, Young Adult, Bacterial Load
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