Characterization of adenovirus-associated virus-induced polypeptides in KB cells
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Electrophoretic analysis of KB cells coinfected with adenovirus-associated virus (AAV) type 2, a defective parvovirus, and adenovirus type 5 (as helper) have revealed the synthesis in vivo of at least five AAV-specific polypeptides. The three largest polypeptides, with molecular weights of 90,700, 71,600, and 60,000 comigrated in polyacrylamide gels with the three AAV structural polypeptides. The remaining two polypeptides had molecular weights of 24,900 and 15,800. The concentrations of the AAV-induced polypeptides relative to one another remained approximately constant during the infectious cycle, and the structural components were present in proportions similar to those found in purified virions. As determined by pulse-chase experiments, all polypeptides were generated at the level of protein synthesis and not by posttranslational proteolytic processing. Although inhibitors of proteolytic enzymes failed to influence the pattern of AAV-induced polypeptides, and amino acid analog, L-canavanine, blocked the appearances of both the major structural polypeptide (60,000 daltons) and the larger nonstructural polypeptide (24,900 daltons). Taken in conjunction with pulse-chase data, this result supports a model whereby the major virion polypeptide is produced by proteolytic cleavage of the nascent polypeptide chain.
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The AAV capsid is composed of 60 subunits of overlapping VP1:VP2:VP3 in an approximate ratio of 1:1:10, assembled with T=1 icosahedral symmetry and a diameter of approximately 260 Å.
“The AAV capsid is composed of 60 subunits of the overlapping VP1:VP2:VP3, in an approximate ratio of 1:1:10, assembled with T = 1 icosahedral symmetry and a diameter of approximately 260 Å [13,14].”
From Understanding Capsid Assembly and Genome Packaging for Adeno-Associated Viruses (2017) · cites this paper as [14]
Cites
Weber, K., & Osborn, M. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)94333-4 · Cited by 16,688 · see citing works
Analysis of bacteriophage T7 early RNAs and proteins on slab gels
Studier, F. W. (1973) · Journal of Molecular Biology · doi:10.1016/0022-2836(73)90003-x · Cited by 2,215 · see citing works
Processing of Adenovirus 2-Induced Proteins
Anderson, C. W., Baum, P. R., & Gesteland, R. F. (1973) · Journal of Virology · doi:10.1128/jvi.12.2.241-252.1973 · Cited by 755 · see citing works
Polypeptide cleavages in the formation of poliovirus proteins.
Jacobson, M. F., & Baltimore, D. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.61.1.77 · Cited by 350 · see citing works
Messenger RNA for the coat protein of tobacco mosaic virus
Hunter, T. R., Hunt, T., Knowland, J., & Zimmern, D. (1976) · Nature · doi:10.1038/260759a0 · Cited by 262 · see citing works
Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus
Ensinger, M. J., & Ginsberg, H. S. (1972) · Journal of Virology · doi:10.1128/jvi.10.3.328-339.1972 · Cited by 246 · see citing works
Marsden, H. S., Crombie, I. K., & Subak-Sharpe, J. H. (1976) · Journal of General Virology · doi:10.1099/0022-1317-31-3-347 · Cited by 207 · see citing works
Structural Proteins of Adenovirus-Associated Viruses
Rose, J. A., Maizel, J. V., Inman, J. K., & Shatkin, A. J. (1971) · Journal of Virology · doi:10.1128/jvi.8.5.766-770.1971 · Cited by 190 · see citing works
Self-citationRose, J. A., Berns, K. I., Hoggan, M. D., & Koczot, F. J. (1969) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.64.3.863 · Cited by 179 · see citing works
Self-citationTranslation of Sindbis virus 26 S RNA and 49 S RNA in lysates of rabbit reticulocytes
Simmons, D. T., & Strauss, J. H. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90027-8 · Cited by 144 · see citing works
Formation of Sindbis Virus Proteins: Identification of a Precursor for One of the Envelope Proteins
Schlesinger, S., & Schlesinger, M. J. (1972) · Journal of Virology · doi:10.1128/jvi.10.5.925-932.1972 · Cited by 141 · see citing works
Lwoff, A. M., & Tournier, P. (1966) · Annual Review of Microbiology · doi:10.1146/annurev.mi.20.100166.000401 · Cited by 133 · see citing works
Berns, K. I., & Rose, J. A. (1970) · Journal of Virology · doi:10.1128/jvi.5.6.693-699.1970 · Cited by 120 · see citing works
Self-citationStructural Proteins of Adenovirus-Associated Virus Type 3
Johnson, F. B., Ozer, H. L., & HOGGAN, M. D. (1971) · Journal of Virology · doi:10.1128/jvi.8.6.860-863.1971 · Cited by 119 · see citing works
Nucleic acid from an adeno-associated virus: chemical and physical studies.
Rose, J. A., HOGGAN, M. D., & Shatkin, A. J. (1966) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.56.1.86 · Cited by 102 · see citing works
Self-citationInitiation sites for translation of sindbis virus 42S and 26S messenger RNAs
Cancedda, R., Villa‐Komaroff, L., Lodish, H. F., & Schlesinger, M. J. (1975) · Cell · doi:10.1016/0092-8674(75)90012-4 · Cited by 102 · see citing works
Summers, D. F., Shaw, E. N., Stewart, M. L., & Maizel, J. V. (1972) · Journal of Virology · doi:10.1128/jvi.10.4.880-884.1972 · Cited by 70 · see citing works
Role of Adenovirus Structural Proteins in the Cessation of Host-Cell Biosynthetic Functions
Levine, A. J., & Ginsberg, H. S. (1968) · Journal of Virology · doi:10.1128/jvi.2.5.430-439.1968 · Cited by 64 · see citing works
Precursor Protein for Newcastle Disease Virus
Samson, A. C. R., & Fox, C. (1973) · Journal of Virology · doi:10.1128/jvi.12.3.579-587.1973 · Cited by 51 · see citing works
Separate Helper Functions provided by Adenovirus for Adenovirus-associated Virus Multiplication
Carter, B. J., Koczot, F. J., Garrison, J. W., ROSE, J. A., & Dolin, R. (1973) · Nature New Biology · doi:10.1038/newbio244071a0 · Cited by 46 · see citing works
Self-citationJohnson, F. B., Blacklow, N. R., & HOGGAN, M. D. (1972) · Journal of Virology · doi:10.1128/jvi.9.6.1017-1026.1972 · Cited by 39 · see citing works
Carter, B. J., & Rose, J. A. (1974) · Virology · doi:10.1016/0042-6822(74)90253-0 · Cited by 32 · see citing works
Self-citationGenome localization of adeno-associated virus RNA
Carter, B. J., Fife, K. H., de la Maza, L. M., & Berns, K. I. (1976) · Journal of Virology · doi:10.1128/jvi.19.3.1044-1053.1976 · Cited by 21 · see citing works
Intracellular distribution and polyadenylate content of adeno-associated virus RNA sequences
Carter, B. J. (1976) · Virology · doi:10.1016/0042-6822(76)90080-5 · Cited by 14 · see citing works
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Opie, S. R., Warrington, Agbandje-McKenna, M., Zolotukhin, S., & Muzyczka, N. (2003) · Journal of Virology · doi:10.1128/jvi.77.12.6995-7006.2003 · Cited by 364 · see citing works
Cloning and Characterization of Adeno-Associated Virus Type 5
Chiorini, J. A., Kim, F., Yang, L. C., & Kotin, R. M. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.1309-1319.1999 · Cited by 332 · see citing works
Herpes Simplex Virus Types 1 and 2 Completely Help Adenovirus-Associated Virus Replication
Buller, R. M. L., Janik, J. E., Sebring, E. D., & Rose, J. A. (1981) · Journal of Virology · doi:10.1128/jvi.40.1.241-247.1981 · Cited by 332 · see citing works
Self-citationHermonat, P. L., Labow, M., Wright, R. L., Berns, K. I., & Muzyczka, N. (1984) · Journal of Virology · doi:10.1128/jvi.51.2.329-339.1984 · Cited by 300 · see citing works
Tratschin, J.-D., Miller, I. L., & Carter, B. J. (1984) · Journal of Virology · doi:10.1128/jvi.51.3.611-619.1984 · Cited by 272 · see citing works
Intracellular trafficking of adeno-associated viral vectors
Ding, W., Zhang, L., Yan, Z., & Engelhardt, J. F. (2005) · Gene Therapy · doi:10.1038/sj.gt.3302527 · Cited by 251 · see citing works
Bucher, K., Rodríguez-Bocanegra, E., Dauletbekov, D., & Fischer, M. D. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100915 · Cited by 242 · see citing works
Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles
Chiorini, J. A., Yang, L., Liu, Y., Safer, B., & Kotin, R. M. (1997) · Journal of Virology · doi:10.1128/jvi.71.9.6823-6833.1997 · Cited by 231 · see citing works
Venkatakrishnan, B., Yarbrough, J., Domsic, J. F., Bennett, A. D., Bothner, B. B., Kozyreva, O. G., Samulski, R. J., Muzyczka, N., McKENNA, R. V., & Agbandje‐McKenna, M. (2013) · Journal of Virology · doi:10.1128/jvi.02524-12 · Cited by 225 · see citing works
Adeno-associated virus capsid assembly is divergent and stochastic
Wörner, T. P., Bennett, A. D., Habka, S., Snijder, J., Friese, O. V., Powers, T. W., Agbandje‐McKenna, M., & Heck, A. J. R. (2021) · Nature Communications · doi:10.1038/s41467-021-21935-5 · Cited by 221 · see citing works
Warrington, K. H., Gorbatyuk, O. S., Harrison, J. K., Opie, S. R., Zolotukhin, S., & Muzyczka, N. (2004) · Journal of Virology · doi:10.1128/jvi.78.12.6595-6609.2004 · Cited by 205 · see citing works
Kronenberg, S., Böttcher, B., von der Lieth, C. W., Bleker, S., & Kleinschmidt, J. A. (2005) · Journal of Virology · doi:10.1128/jvi.79.9.5296-5303.2005 · Cited by 198 · see citing works
Twenty-Five Years of Structural Parvovirology
Mietzsch, M., Pénzes, J. J., & Agbandje-McKenna, M. (2019) · Viruses · doi:10.3390/v11040362 · Cited by 197 · see citing works
Analysis of proteins, helper dependence, and seroepidemiology of a new human parvovirus
Georg‐Fries, B., Biederlack, S., Wolf, J., & Hausen, H. Z. (1984) · Virology · doi:10.1016/0042-6822(84)90272-1 · Cited by 197 · see citing works
Snijder, J., van de Waterbeemd, M., Damoc, E., Denisov, E., Grinfeld, D., Bennett, A., Agbandje-McKenna, M., Makarov, A., & Heck, A. J. R. (2014) · Journal of the American Chemical Society · doi:10.1021/ja502616y · Cited by 168 · see citing works
Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon.
Becerra, S., Rose, J. A., Hardy, M. M., Baroudy, B. M., & Anderson, C. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.23.7919 · Cited by 166 · see citing works
Self-citationEnhancement of Adeno-Associated Virus Infection by Mobilizing Capsids into and Out of the Nucleolus
Johnson, J. S., & Samulski, R. J. (2008) · Journal of Virology · doi:10.1128/jvi.02309-08 · Cited by 158 · see citing works
Comparative Analysis of Adeno-Associated Virus Capsid Stability and Dynamics
Rayaprolu, V., Kruse, S., Kant, R., Venkatakrishnan, B., Movahed, N., Brooke, D. J., Lins, B., Bennett, A. D., Potter, T., McKENNA, R. V., et al. (2013) · Journal of Virology · doi:10.1128/jvi.01415-13 · Cited by 161 · see citing works
Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry
Pierson, E. E., Keifer, D. Z., Asokan, A., & Jarrold, M. F. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b00883 · Cited by 152 · see citing works
Applications of Charge Detection Mass Spectrometry in Molecular Biology and Biotechnology
Jarrold, M. F. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00377 · Cited by 156 · see citing works
Wistuba, A., Weger, S., Kern, A., & Kleinschmidt, J. A. (1995) · Journal of Virology · doi:10.1128/jvi.69.9.5311-5319.1995 · Cited by 147 · see citing works
Mendelson, E., Trempe, J. P., & Carter, B. J. (1986) · Journal of Virology · doi:10.1128/jvi.60.3.823-832.1986 · Cited by 143 · see citing works
Ruffing, M., Zentgraf, H., & Kleinschmidt, J. A. (1992) · Journal of Virology · doi:10.1128/jvi.66.12.6922-6930.1992 · Cited by 109 · see citing works
Berns, K. I., & Hauswirth, W. W. (1979) · Advances in virus research · doi:10.1016/s0065-3527(08)60574-6 · Cited by 108 · see citing works
Assembly of adeno-associated virus
Myers, M. W., & Carter, B. J. (1980) · Virology · doi:10.1016/0042-6822(80)90071-9 · Cited by 107 · see citing works
Johnson, J. S., Li, C., DiPrimio, N., Weinberg, M. S., McCown, T. J., & Samulski, R. J. (2010) · Journal of Virology · doi:10.1128/jvi.00687-10 · Cited by 105 · see citing works
Adeno-Associated Virus Type 2 Protein Interactions: Formation of Pre-Encapsidation Complexes
Dubielzig, R., King, J., Weger, S., Kern, A., & Kleinschmidt, J. A. (1999) · Journal of Virology · doi:10.1128/jvi.73.11.8989-8998.1999 · Cited by 105 · see citing works
Adeno-associated Virus (AAV) Dual Vector Strategies for Gene Therapy Encoding Large Transgenes.
McClements, M. E., & MacLaren, R. E. (2017) · PubMed Central · Cited by 95 · see citing works
Cloning of an Avian Adeno-Associated Virus (AAAV) and Generation of Recombinant AAAV Particles
Bossis, I., & Chiorini, J. A. (2003) · Journal of Virology · doi:10.1128/jvi.77.12.6799-6810.2003 · Cited by 93 · see citing works
Kondratov, O., Marsic, D., Crosson, S. M., Méndez‐Gómez, H. R., Moskalenko, O. V., Mietzsch, M., Heilbronn, R., Allison, J. R., Green, K. B., Agbandje‐McKenna, M., et al. (2017) · Molecular Therapy · doi:10.1016/j.ymthe.2017.08.003 · Cited by 92 · see citing works
Adeno-associated Virus as a Mammalian DNA Vector
Salganik, M., Hirsch, M. L., & Samulski, R. J. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.mdna3-0052-2014 · Cited by 88 · see citing works
Barnes, L. F., Draper, B. E., Chen, Y., Powers, T. W., & Jarrold, M. F. (2021) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2021.08.002 · Cited by 85 · see citing works
Qiu, J., & Brown, K. E. (1999) · Virology · doi:10.1006/viro.1999.9664 · Cited by 86 · see citing works
Mapping of the 5' termini of two adeno-associated virus 2 RNAs in the left half of the genome
Lusby, E. W., & Berns, K. I. (1982) · Journal of Virology · doi:10.1128/jvi.41.2.518-526.1982 · Cited by 86 · see citing works
Understanding Capsid Assembly and Genome Packaging for Adeno-Associated Viruses
Bennett, A., Mietzsch, M., & Agbandje-McKenna, M. (2017) · Future Virology · doi:10.2217/fvl-2017-0011 · Cited by 82 · see citing works
Altering AAV tropism with mosaic viral capsids
Gigout, L. I., Rebollo, P., Clement, N., Warrington, K. H., Muzyczka, N., Linden, R. M., & Weber, T. (2005) · Molecular Therapy · doi:10.1016/j.ymthe.2005.03.005 · Cited by 79 · see citing works
Bloom, M. E., Race, R., & Wolfinbarger, J. B. (1982) · Journal of Virology · doi:10.1128/jvi.43.2.608-616.1982 · Cited by 79 · see citing works
Jay, F. T., LAUGHLIN, C. A., & Carter, B. J. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.5.2927 · Cited by 76 · see citing works
Cassinotti, P., Weitzand, M., & Tratschin, J.-D. (1988) · Virology · doi:10.1016/0042-6822(88)90067-0 · Cited by 75 · see citing works
AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo
Powell, S., Samulski, R. J., & McCown, T. J. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.03.007 · Cited by 70 · see citing works
Tseng, Y.-S., Gurda, B. L., Chipman, P. R., McKENNA, R. V., Afione, S. A., Chiorini, J. A., Muzyczka, N., Olson, N. H., Baker, T. S., Kleinschmidt, J. A., et al. (2014) · Journal of Virology · doi:10.1128/jvi.02710-14 · Cited by 69 · see citing works
Hoque, M., Ishizu, K., Matsumoto, A., Han, S., Arisaka, F., Takayama, M., Suzuki, K., Kenzo, K. A. T. O., Kanda, T., Watanabe, H., et al. (1999) · Journal of Virology · doi:10.1128/jvi.73.9.7912-7915.1999 · Cited by 70 · see citing works
Structure of neurotropic adeno-associated virus AAVrh.8
Halder, S., Vliet, K. V., Smith, J. K., Duong, T. T. P., McKENNA, R. V., Wilson, J. M., & Agbandje‐McKenna, M. (2015) · Journal of Structural Biology · doi:10.1016/j.jsb.2015.08.017 · Cited by 62 · see citing works
Jin, X., Liu, L., Nass, S., O’Riordan, C. R., Pastor, E., & Zhang, X. K. (2017) · Human Gene Therapy Methods · doi:10.1089/hgtb.2016.178 · Cited by 62 · see citing works
AAV for Gene Therapy in Ocular Diseases: Progress and Prospects
He, X., Fu, Y., Ma, L., Yao, Y., Ge, S., Yang, Z. H., & Fan, X. (2023) · Research · doi:10.34133/research.0291 · Cited by 59 · see citing works
Ebberink, E. H. T. M., Ruisinger, A., Nuebel, M., Thomann, M., & Heck, A. J. R. (2022) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2022.11.003 · Cited by 60 · see citing works
The X Gene of Adeno-Associated Virus 2 (AAV2) Is Involved in Viral DNA Replication
Cao, M., You, H., & Hermonat, P. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104596 · Cited by 54 · see citing works
Drouin, L. M., Lins, B., Janssen, M., Bennett, A. D., Chipman, P. R., McKENNA, R. V., Chen, W., Muzyczka, N., Giovanni Cardone, A., Baker, T. S., et al. (2016) · Journal of Virology · doi:10.1128/jvi.00575-16 · Cited by 52 · see citing works
Incorporation of modified amino acids into proteins in vivo
Wilson, M. J., & Hatfield, D. L. (1984) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/0167-4781(84)90085-x · Cited by 50 · see citing works
Hölscher, C., Hörer, M., Kleinschmidt, J. A., Zentgraf, H., Bürkle, A., & Heilbronn, R. (1994) · Journal of Virology · doi:10.1128/jvi.68.11.7169-7177.1994 · Cited by 50 · see citing works
Virally coded noncapsid protein associated with bovine parvovirus infection
Lederman, M., Patton, J. T., Stout, E. R., & Bates, R. C. (1984) · Journal of Virology · doi:10.1128/jvi.49.2.315-318.1984 · Cited by 49 · see citing works
Adeno-associated virus proteins: origin of the capsid components
Janik, J. E., Huston, M. M., & Rose, J. A. (1984) · Journal of Virology · doi:10.1128/jvi.52.2.591-597.1984 · Cited by 47 · see citing works
Self-citationBarnes, L. F., Draper, B. E., & Jarrold, M. F. (2022) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2022.10.008 · Cited by 45 · see citing works
Oyama, H., Ishii, K., Maruno, T., Torisu, T., & Uchiyama, S. (2021) · Human Gene Therapy · doi:10.1089/hum.2021.009 · Cited by 41 · see citing works
The structure of AAVrh32.33, a novel gene delivery vector
Mikals, K., Nam, H.-J., Vliet, K. V., Vandenberghe, L. H., Mays, L. E., McKENNA, R. V., Wilson, J. M., & Agbandje‐McKenna, M. (2014) · Journal of Structural Biology · doi:10.1016/j.jsb.2014.03.020 · Cited by 40 · see citing works
Adeno-Associated Virus DNA Structure and Replication
Berns, K. I., & Hauswirth, W. W. (1984) · Springer eBooks · doi:10.1007/978-1-4684-8012-2_1 · Cited by 37 · see citing works
Słyk, Ż., Stachowiak, N., & Małecki, M. (2024) · Biomedicines · doi:10.3390/biomedicines12071523 · Cited by 39 · see citing works
Can ACG Serve as an Initiation Codon for Protein Synthesis in Eucaryotic Cells?
Anderson, C. W., & Buzash-Pollert, E. (1985) · Molecular and Cellular Biology · doi:10.1128/mcb.5.12.3621 · Cited by 34 · see citing works
Adeno-associated Virus Type 2: A Latent Life Cycle
Leonard, C. J., & Berns, K. I. (1994) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60852-1 · Cited by 33 · see citing works
Tijssen, P., & Kurstak, E. (1981) · Journal of Virology · doi:10.1128/jvi.37.1.17-23.1981 · Cited by 31 · see citing works
Onishi, T., Nonaka, M., Maruno, T., Yamaguchi, Y., Fukuhara, M., Torisu, T., Maeda, M., Abbatiello, S. E., Haris, A., Richardson, K., et al. (2023) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2023.101142 · Cited by 29 · see citing works
A comparison of AAV-vector production methods for gene therapy and preclinical assessment
Davidsson, M., Negrini, M., Hauser, S., Svanbergsson, A., Lockowandt, M., Tomasello, G., Manfredsson, F. P., & Heuer, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-78521-w · Cited by 28 · see citing works
Horowitz, E. D., Finn, M. G., & Asokan, A. (2012) · ACS Chemical Biology · doi:10.1021/cb3000265 · Cited by 28 · see citing works
Chimeric Virus-like Particle Formation of Adeno-Associated Virus
Hoque, M., Shimizu, N., Ishizu, K., Yajima, H., Arisaka, F., Suzuki, K., Watanabe, H., & Handa, H. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1831 · Cited by 28 · see citing works
López-Astacio, R. A., Adu, O. F., Lee, H., Hafenstein, S. L., & Parrish, C. R. (2023) · Journal of Virology · doi:10.1128/jvi.00161-23 · Cited by 27 · see citing works
Polycistronic Animal Virus mRNAs
Samuel, C. E. (1989) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60697-2 · Cited by 26 · see citing works
Adeno-Associated Virus Defectiveness and the Nature of the Adenovirus Helper Function
Carter, B. J., & LAUGHLIN, C. A. (1984) · Springer eBooks · doi:10.1007/978-1-4684-8012-2_3 · Cited by 26 · see citing works
Nuclear translocation of adeno-associated virus type 2 capsid proteins for virion assembly
Popa-Wagner, R., Sonntag, F., Schmidt, K., King, J., & Kleinschmidt, J. A. (2012) · Journal of General Virology · doi:10.1099/vir.0.043232-0 · Cited by 24 · see citing works
Structural proteins of adenovirus-associated virus: subspecies and their relatedness
McPherson, R. A., & Rose, J. A. (1983) · Journal of Virology · doi:10.1128/jvi.46.2.523-529.1983 · Cited by 24 · see citing works
Self-citationRole of the membrane-associated accessory protein (MAAP) in adeno-associated virus (AAV) infection
Küz, Ç. A., Ning, K., Hao, S., Cheng, F., & Qiu, J. (2024) · Journal of Virology · doi:10.1128/jvi.00633-24 · Cited by 25 · see citing works
AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition
Bennett, A. D., Wong, K., Lewis, J., Tseng, Y.-S., Smith, J. K., Chipman, P. R., McKENNA, R. V., Samulski, R. J., Kleinschmidt, J. A., & Agbandje‐McKenna, M. (2018) · Virology · doi:10.1016/j.virol.2018.03.007 · Cited by 23 · see citing works
He, X. Z., Powers, T. W., Huang, S., Liu, Z., Shi, H., Orlet, J. D., Mo, J. J., Srinivasan, S., Jacobs, S., Zhang, K., et al. (2023) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2023.03.002 · Cited by 21 · see citing works
Troxell, B., Tsai, I.-W., Shah, K., Knuckles, C. I., Shelton, S., Lindsey, K., Cardenas, S. M. B., & Roberts, T. (2023) · Human Gene Therapy · doi:10.1089/hum.2022.218 · Cited by 20 · see citing works
Nakatsuka, R., Yamaguchi, Y., Hirohata, K., Shimojo, S., Murakami, M., Rocafort, M. A. V., Tsunaka, Y., Fukuhara, M., Torisu, T., & Uchiyama, S. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c05229 · Cited by 20 · see citing works
Multiparametric domain insertional profiling of adeno-associated virus VP1
Hoffmann, M. D., Zdechlik, A. C., He, Y., Nedrud, D. M., Aslanidi, G., Gordon, W. R., & Schmidt, D. (2023) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2023.101143 · Cited by 17 · see citing works
Effects of Thermally Induced Configuration Changes on rAAV Genome’s Enzymatic Accessibility
Xu, Y., Guo, P., Zhang, J., Chrzanowski, M., Chew, H., Firrman, J., Sang, N., Diao, Y., & Xiao, W. (2020) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2020.06.005 · Cited by 17 · see citing works
Buller, R. M. L., Straus, S. E., & Rose, J. A. (1979) · Journal of General Virology · doi:10.1099/0022-1317-43-3-663 · Cited by 17 · see citing works
Self-citationStructural and Biophysical Analysis of Adeno-Associated Virus Serotype 2 Capsid Assembly Variants
Bennett, A. D., Gargas, J., Kansol, A., Lewis, J., Hsi, J., Hull, J. A., Mietzsch, M., Tartaglia, L. J., Muzyczka, N., Bhattacharya, N., et al. (2023) · Journal of Virology · doi:10.1128/jvi.01772-22 · Cited by 19 · see citing works
Biophysical and structural insights into AAV genome ejection
Gliwa, K., Hull, J. A., Kansol, A., Zembruski, V., Lakshmanan, R., Mietzsch, M., Chipman, P. R., Bennett, A. D., & McKENNA, R. V. (2025) · Journal of Virology · doi:10.1128/jvi.00899-24 · Cited by 16 · see citing works
Salo, R. J., & Mayor, H. D. (1979) · Virology · doi:10.1016/0042-6822(79)90291-5 · Cited by 16 · see citing works
Structural and antigenic characterization of the avian adeno-associated virus capsid
Hsi, J., Mietzsch, M., Chipman, P., Afione, S., Zeher, A., Huang, R. K., Chiorini, J., & McKenna, R. (2023) · Journal of Virology · doi:10.1128/jvi.00780-23 · Cited by 15 · see citing works
Engineered CHO cells as a novel AAV production platform for gene therapy delivery
Nagy, A., Chakrabarti, L., Kurasawa, J. H., Mulagapati, S. H. R., Devine, P., Therres, J., Chen, Y., & Schmelzer, A. E. (2023) · Scientific Reports · doi:10.1038/s41598-023-46298-3 · Cited by 15 · see citing works
Lederman, M., Cotmore, S. F., Stout, E. R., & Bates, R. C. (1987) · Journal of Virology · doi:10.1128/jvi.61.11.3612-3616.1987 · Cited by 15 · see citing works
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2
Bennett, A. D., Hull, J. A., Jolinon, N., Tordo, J., Moss, K., Binns, E., Mietzsch, M., Hagemann, C., Linden, R. M., Serio, A., et al. (2021) · Journal of Structural Biology · doi:10.1016/j.jsb.2021.107795 · Cited by 13 · see citing works
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye
Ng, B., Kaukonen, M. K., McClements, M. E., Shamsnajafabadi, H., MacLaren, R. E., & Cehajic‐Kapetanovic, J. (2024) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2024.101289 · Cited by 13 · see citing works
Partial genome content within rAAVs impacts performance in a cell assay-dependent manner
Troxell, B., Jaslow, S. L., Tsai, I.-W., Sullivan, C. S., Draper, B. E., Jarrold, M. F., Lindsey, K., & Blue, L. (2023) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2023.07.007 · Cited by 13 · see citing works
Structural and nonstructural proteins of a rabbit parvovirus
Matsunaga, Y., & Matsuno, S. (1983) · Journal of Virology · doi:10.1128/jvi.45.2.627-633.1983 · Cited by 13 · see citing works
Reversible Inhibition of Bovine Parvovirus DNA Replication by Aphidicolin and L-Canavanine
Robertson, A. T., Bates, R. C., & Stout, E. R. (1984) · Journal of General Virology · doi:10.1099/0022-1317-65-9-1497 · Cited by 13 · see citing works
Structural characterization of an envelope-associated adeno-associated virus type 2 capsid
Hull, J. A., Mietzsch, M., Chipman, P. R., Strugatsky, D., & McKENNA, R. V. (2021) · Virology · doi:10.1016/j.virol.2021.09.010 · Cited by 12 · see citing works
Variant and Defective Interfering Parvoviruses
Carter, B. J. (1984) · Springer eBooks · doi:10.1007/978-1-4684-8012-2_6 · Cited by 12 · see citing works
Johnson, F. B. (1984) · Springer eBooks · doi:10.1007/978-1-4684-8012-2_7 · Cited by 12 · see citing works
Molecular homology among the structural proteins of densonucleosis virus from silkworm,Bombyx mori
Bando, H., Kondo, N., & Kawase, S. (1984) · Archives of Virology · doi:10.1007/bf01310660 · Cited by 11 · see citing works
Developing New Vectors for Retinal Gene TherapyPreprint
Zin, E. A., Öztürk, B. E., Dalkara, D., & Byrne, L. C. (2023) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041291 · Cited by 12 · see citing works
Iroanya, G. I., Subramanyam, P. N., Wells, K. D., & Green, J. A. (2025) · Human Gene Therapy · doi:10.1177/10430342251378524 · Cited by 10 · see citing works
Mnyandu, N., Arbuthnot, P. B., & Maepa, M. B. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0290-4_10 · Cited by 10 · see citing works
Berns, K. I. (1984) · Springer eBooks · doi:10.1007/978-1-4684-7935-5_13 · Cited by 10 · see citing works
Powell, S., & McCown, T. J. (2024) · Journal of Virology · doi:10.1128/jvi.01681-24 · Cited by 10 · see citing works
Carter, B. J., LAUGHLIN, C. A., & Marcus-Sekura, C. J. (1984) · Springer eBooks · doi:10.1007/978-1-4684-8012-2_5 · Cited by 9 · see citing works
Transcription and translation in the autonomous parvovirus KRV
Mitra, R., Wali, T. M., Valdez, V., Fabisch, P. H., & Salzman, L. A. (1983) · Virology · doi:10.1016/0042-6822(83)90207-6 · Cited by 9 · see citing works
Chen, M. Y., Chen, W., Tong, J., Ho, M., & Suh, J. (2021) · Virology · doi:10.1016/j.virol.2021.08.010 · Cited by 8 · see citing works
- Authors
- Buller, R. M., & Rose, J. A.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1978-01
- Volume
- 25
- Issue
- 1
- Pages
- 331-338
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- PMC
- PMC353931
- OpenAlex
- W1517847098
- Cited by
- 111
- References
- 24
- Citations by year
- 2025: 2 · 2024: 6 · 2023: 11 · 2022: 2 · 2021: 8 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 4 · 2016: 2 · 2015: 3 · 2014: 4 · 2013: 3 · 2012: 2
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Virology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parvovirus B19 Infection Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Virus-based gene therapy research
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Keywords
- KB cells, proteolytic processing, L-canavanine, pulse-chase labeling, viral protein synthesis, infectious cycle
- MeSH terms
- Adenoviruses, Human, Canavanine, Cell Line, Humans, Molecular Weight, Parvoviridae, Peptide Biosynthesis, Phenylmethylsulfonyl Fluoride, Satellite Viruses, Tosyllysine Chloromethyl Ketone, Tosylphenylalanyl Chloromethyl Ketone, Viral Proteins, Virus Replication
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