The DOI matches its Crossref record.
Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization
Open accessAbstract
The gene encoding the fusogenic spike protein of the coronavirus causing feline infectious peritonitis was recombined into the genome of vaccinia virus. The recombinant induced spike-protein-specific, in vitro neutralizing antibodies in mice. When kittens were immunized with the recombinant, low titers of neutralizing antibodies were obtained. After challenge with feline infectious peritonitis virus, these animals succumbed earlier than did the control group immunized with wild-type vaccinia virus (early death syndrome).
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Metadata
- Authors
- Vennema, H., de Groot, R. J., Harbour, D. A., Dalderup, M., Gruffydd-Jones, T., Horzinek, M. C., & Spaan, W. J.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1990-03
- Volume
- 64
- Issue
- 3
- Pages
- 1407-1409
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W1876888557
- Cited by
- 277
- References
- 0
- FWCI
- 12.32
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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