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mRNA Decay Mediated by Two Distinct AU-Rich Elements from c- fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation

Chen, Chyi-Ying A., Xu, Nianhua, Shyu, Ann-Bin·1995·Molecular and Cellular Biology
DOI 10.1128/mcb.15.10.5777
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  • Binding of destabilizing RBPs to AREs results in recruitment of deadenylases, leading to rapid deadenylation, decapping, and ultimately degradation of the target mRNA.

    “The binding of destabilizing RBPs to the AREs results in recruitment of deadenylases, leading to rapid deadenylation, decapping, and ultimately degradation of the target mRNA [28].”

    From The low-density lipoprotein receptor: Emerging post-transcriptional regulatory mechanisms (2025) · cites this paper as [28]

    The Abstract reports that c-fos and GM-CSF AREs direct rapid deadenylation as the first step in mRNA degradation. The Discussion proposes that ARE-associated RNA–protein complexes could recruit RNases, but presents recruitment as a possible mechanism, not an established result. It describes subsequent degradation by exonuclease or endonuclease and does not establish the claimed decapping step. Page numbers were not supplied for these passages. (LLM, conf=0.88)

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Research works printed but not linked: 29

  1. 10.1128/mcb.13.3.1971-1980.1993 · DOI
  2. 10.1016/0092-8674(95)90326-7 · DOI
  3. 10.1128/mcb.9.2.659-670.1989 · DOI
  4. 10.1128/mcb.11.6.3288-3295.1991 · DOI
  5. 10.1126/science.8036511 · DOI
  6. 10.1073/pnas.83.6.1670 · DOI
  7. 10.1128/mcb.14.1.416-426.1994 · DOI
  8. 10.1128/mcb.14.12.8471-8482.1994 · DOI
  9. 10.1016/S0021-9258(18)52955-0 · DOI
  10. Higuchi, R. 1990. Recombinant PCR, p. 177–183. In M. A. Innis, D. H. Gelfand, J. J. Sninsky, and T. J. White (ed.), PCR protocols: a guide to methods and applications. Academic Press, San Diego, Calif.
  11. 10.1093/nar/22.2.238 · DOI
  12. 10.1073/pnas.88.17.7778 · DOI
  13. 10.1128/mcb.9.11.5134-5142.1989 · DOI
  14. 10.1128/mcb.14.12.7984-7995.1994 · DOI
  15. 10.1126/science.2540528 · DOI
  16. 10.1101/gad.6.11.2088 · DOI
  17. 10.1038/355730a0 · DOI
  18. 10.1128/mr.59.3.423-450.1995 · DOI · Paper page
  19. 10.1016/0092-8674(93)80043-E · DOI · Paper page
  20. 10.1101/gad.6.10.1927 · DOI
  21. 10.1016/S0021-9258(17)41882-5 · DOI
  22. 10.1016/0092-8674(88)90256-5 · DOI
  23. 10.1016/0092-8674(86)90341-7 · DOI
  24. Sheiness, D., and J. E. Darnell. 1973. Polyadenylic acid segment in mRNA becomes shorter with age. Nature (London) 241:265–268.
  25. 10.1101/gad.5.2.221 · DOI
  26. 10.1101/gad.3.1.60 · DOI
  27. 10.1128/MCB.15.7.3796 · DOI
  28. 10.1128/mcb.12.7.2931-2940.1992 · DOI
  29. 10.1128/MCB.15.4.2219 · DOI

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Metadata

Authors
Chen, C.-Y. A., Xu, N., & Shyu, A.-B.
Affiliations
Department of Biochemistry and Molecular Biology, Medical School, The University of Texas Houston Health Science Center
Venue
Molecular and Cellular Biology
Publisher
Informa UK Limited
Published
1995-10
Volume
15
Issue
10
Pages
5777-5788
ISSN
1098-5549
DOI
10.1128/mcb.15.10.5777
Cited by
231
References
0
Language
en
Licence
journals.asm.org/non-commercial-tdm-license (tdm)

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