Identification of HuR as a protein implicated in AUUUA‐mediated mRNA decay

Molecular Cloning: A Laboratory Manual

Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589 · see citing works

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

Dignam, J. D., Lebovitz, R. M., & Roeder, R. G. (1983) · Nucleic Acids Research · doi:10.1093/nar/11.5.1475 · Cited by 11,262 · see citing works

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

Cleveland, D. W., Fischer, S. G., Kirschner, M. W., & Laemmli, U. K. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75212-0 · Cited by 5,556 · see citing works

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Shaw, G. D., & Kamen, R. (1986) · Cell · doi:10.1016/0092-8674(86)90341-7 · Cited by 3,946 · see citing works

AU-rich elements: characterization and importance in mRNA degradation

Chen, C.-Y. A., & Shyu, A.-B. (1995) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)89102-1 · Cited by 1,948 · see citing works

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

Caput, D., Beutler, B., Hartog, K., Thayer, R. M., Brown-Shimer, S. L., & Cerami, A. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.6.1670 · Cited by 1,516 · see citing works

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

Lindstein, T., June, C. H., Ledbetter, J. A., Stella, G. C. L., & Thompson, C. B. (1989) · Science · doi:10.1126/science.2540528 · Cited by 866 · see citing works

Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein

Ma, W.-J., Cheng, S., Campbell, C., Wright, A., & Furneaux, H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.14.8144 · Cited by 667 · see citing works

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.Preprint

Shyu, A. B., Greenberg, M. E., & Belasco, J. G. (1989) · Genes & Development · doi:10.1101/gad.3.1.60 · Cited by 606 · see citing works

c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

Miller, A. D., Curran, T., & Verma, I. M. (1984) · Cell · doi:10.1016/0092-8674(84)90073-4 · Cited by 601 · see citing works

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

Greenberg, M. E., Hermanowski, A. L., & Ziff, E. B. (1986) · Molecular and Cellular Biology · doi:10.1128/mcb.6.4.1050 · Cited by 549 · see citing works

The Nonamer UUAUUUAUU Is the Key AU-Rich Sequence Motif That Mediates mRNA Degradation

Zubiaga, A. M., Belasco, J. G., & Greenberg, M. E. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.4.2219 · Cited by 543 · see citing works

Purification, Characterization, and cDNA Cloning of an AU-Rich Element RNA-Binding Protein, AUF1

Zhang, W., Wagner, B., Ehrenman, K., Schaefer, A., DeMaria, C. T., Crater, D. L., DeHaven, K., Long, L., & Brewer, G. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.12.7652 · Cited by 540 · see citing works

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.Preprint

Shyu, A. B., Belasco, J. G., & Greenberg, M. E. (1991) · Genes & Development · doi:10.1101/gad.5.2.221 · Cited by 523 · see citing works

Identification of an AUUUA-Specific Messenger RNA Binding Protein

Malter, J. S. (1989) · Science · doi:10.1126/science.2814487 · Cited by 497 · see citing works

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

Brewer, G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.5.2460 · Cited by 479 · see citing works

Detection of the anti‐Hu antibody in the serum of patients with small cell lung cancer—A quantitative western blot analysis

Dalmau, J. O., Furneaux, H. M., Gralla, R. J., Kris, M. G., & Posner, J. B. (1990) · Annals of Neurology · doi:10.1002/ana.410270515 · Cited by 391 · see citing works

Control of Messenger RNA Stability

(1993) · Elsevier eBooks · doi:10.1016/c2009-0-03269-3 · Cited by 386 · see citing works

Neuronal antinuclear antibody in sensory neuronopathy from lung cancer

Graus, F., Cordon‐Cardo, C., & Posner, J. B. (1985) · Neurology · doi:10.1212/wnl.35.4.538 · Cited by 367 · see citing works

Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

Levine, T., Gao, F., King, P. H., Andrews, L. G., & Keene, J. D. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3494 · Cited by 356 · see citing works

AUUUA Is Not Sufficient To Promote Poly(A) Shortening and Degradation of an mRNA: the Functional Sequence within AU-Rich Elements May Be UUAUUUA(U/A)(U/A)

Lagnado, C. A., Brown, C. Y., & Goodall, G. J. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.7984-7995.1994 · Cited by 335 · see citing works

A conserved family of elav-like genes in vertebrates.

Good, P. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.10.4557 · Cited by 319 · see citing works

The elav Gene Product of Drosophila , Required in Neurons, Has Three RNP Consensus Motifs

Robinow, S., Campos, A. R., Yao, K., & White, K. (1988) · Science · doi:10.1126/science.3144044 · Cited by 300 · see citing works

An Inducible Cytoplasmic Factor (AU-B) Binds Selectively to AUUUA Multimers in the 3′ Untranslated Region of Lymphokine mRNA

Bohjanen, P. R., Petryniak, B., June, C. H., Thompson, C. B., & Lindsten, T. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3288 · Cited by 288 · see citing works

mRNA Decay Mediated by Two Distinct AU-Rich Elements from c- fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation

Chen, C. A., Xu, N., & Shyu, A. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.10.5777 · Cited by 275 · see citing works

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

Vakalopoulou, E., Schaack, J. B., & Shenk, T. E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3355 · Cited by 266 · see citing works

Selective Degradation of Early-Response-Gene mRNAs: Functional Analyses of Sequence Features of the AU-Rich Elements

Chen, C. A., & Shyu, A. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8471-8482.1994 · Cited by 252 · see citing works

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

Gillis, P., & Malter, J. S. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)49970-x · Cited by 224 · see citing works

Mutant Alleles at the Locus elav in Drosophila melanogaster lead to Nervous System Defects. A Developmental-Genetic Analysis

Campos, A. R., And, D. G., & White, K. (1985) · Journal of Neurogenetics · doi:10.3109/01677068509100150 · Cited by 210 · see citing works

Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences.

Hamilton, B. J., Nagy, E., Malter, J. S., Arrick, B. A., & Rigby, W. F. C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)52955-0 · Cited by 209 · see citing works

GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor

Schuler, G. D., & Cole, M. D. (1988) · Cell · doi:10.1016/0092-8674(88)90256-5 · Cited by 209 · see citing works

Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene.

Meijlink, F. C. P. W., Curran, T., Miller, A. D., et al. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.15.4987 · Cited by 208 · see citing works

Interplay of two functionally and structurally distinct domains of the c- fos AU-rich element specifies its mRNA-destabilizing function

Chen, C.-Y. A., Chen, T.-M., & Shyu, A. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.1.416-426.1994 · Cited by 185 · see citing works

Transcription-Dependent and Transcription-Independent Nuclear Transport of hnRNP Proteins

Piñol-Roma, S., & Dreyfuss, G. (1991) · Science · doi:10.1126/science.1857966 · Cited by 185 · see citing works

Purification, Characterization, and cDNA Cloning of an AU-Rich Element RNA-Binding Protein, AUF1

Zhang, W., Wagner, B. J., Ehrenman, K., et al. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.12.7652-7665.1993 · Cited by 182 · see citing works

A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

Malter, J. S., & Hong, Y. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)49969-3 · Cited by 181 · see citing works

Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex.Preprint

Savant‐Bhonsale, S., & Cleveland, D. W. (1992) · Genes & Development · doi:10.1101/gad.6.10.1927 · Cited by 173 · see citing works

AU RNA-binding factors differ in their binding specificities and affinities.

Bohjanen, P. R., Petryniak, B., June, C. H., Thompson, C. B., & Lindsten, T. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42696-8 · Cited by 156 · see citing works

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.

Gao, F., Carson, C. C., Levine, T., & Keene, J. D. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.11207 · Cited by 156 · see citing works

Functional Characterization of a Non-AUUUA AU-Rich Element from the c-jun Proto-Oncogene mRNA: Evidence for a Novel Class of AU-Rich Elements

Peng, S., Chen, C. A., & Shyu, A. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.4.1490 · Cited by 152 · see citing works

Selective Destabilization of Short-Lived mRNAs with the Granulocyte-Macrophage Colony-Stimulating Factor AU-Rich 3' Noncoding Region Is Mediated by a Cotranslational Mechanism

Aharon, T., & Schneider, R. J. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.3.1971-1980.1993 · Cited by 135 · see citing works

AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity.

Nakagawa, J., Waldner, H., Meyer‐Monard, S., Hofsteenge, J., Jenö, P., & Moroni, C. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.6.2051 · Cited by 132 · see citing works

U-Rich Sequence-Binding Proteins (URBPs) Interacting with a 20-Nucleotide U-Rich Sequence in the 3′ Untranslated Region of c-fos mRNA May Be Involved in the First Step of c-fos mRNA Degradation

You, Y., Chen, C. Y., & Shyu, A. B. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.7.2931 · Cited by 129 · see citing works

Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.

Koeller, D. M., Horowitz, J. A., Casey, J. L., et al. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.17.7778 · Cited by 129 · see citing works

An A+U-Rich Element RNA-Binding Factor Regulates c- myc mRNA Stability In Vitro

Brewer, G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.5.2460-2466.1991 · Cited by 123 · see citing works

Four novel U RNAs are encoded by a herpesvirus

Lee, S. I., Murthy, S. C., Trimble, J. J., Desrosiers, R. C., & STEITZ, J. A. (1988) · Cell · doi:10.1016/s0092-8674(88)80004-7 · Cited by 115 · see citing works

Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

Levine, T., Gao, F., King, P. H., et al. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3494-3504.1993 · Cited by 109 · see citing works

Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos protein.

Lee, W. M. F., Lin, C. J., & Curran, T. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.12.5521 · Cited by 100 · see citing works

Identification of early neurogenic cells in the neural crest lineage

Marusich, M. F., & Weston, J. A. (1992) · Developmental Biology · doi:10.1016/0012-1606(92)90285-o · Cited by 98 · see citing works

Identification of sequences within the murine granulocyte-macrophage colony-stimulating factor mRNA 3'-untranslated region that mediate mRNA stabilization induced by mitogen treatment of EL-4 thymoma cells.

Iwai, Y., Bickel, M., Pluznik, D. H., & Cohen, R. B. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55222-4 · Cited by 87 · see citing works

AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm

Katz, D. A., Theodorakis, N. D., Cleveland, D. W., & Lindsten, T. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.2.238 · Cited by 78 · see citing works

Rapid Degradation of AU-Rich Element (ARE) mRNAs Is Activated by Ribosome Transit and Blocked by Secondary Structure at Any Position 5′ to the ARE

Curatola, A. M., Nadal, M. S., & Schneider, R. J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.11.6331 · Cited by 75 · see citing works

Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.

Myer, V. E., Lee, S. I., & Steitz, J. A. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.4.1296 · Cited by 74 · see citing works

An Inducible Cytoplasmic Factor (AU-B) Binds Selectively to AUUUA Multimers in the 3′ Untranslated Region of Lymphokine mRNA

Bohjanen, P. R., Petryniak, B., June, C. H., et al. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3288-3295.1991 · Cited by 73 · see citing works

Control of messenger RNA stability

Beaud, G. (1994) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(94)90155-4 · Cited by 65 · see citing works

Rapid mRNA Degradation Mediated by the c- fos 3′ AU-Rich Element and That Mediated by the Granulocyte-Macrophage Colony-Stimulating Factor 3′ AU-Rich Element Occur through Similar Polysome-Associated Mechanisms

Winstall, É., Gamache, M., & Raymond, V. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.7.3796 · Cited by 57 · see citing works

Isolation and characterization of a novel, low abundance hnRNP protein: A0.

Myer, V. E., & Steitz, J. A. (1995) · PubMed · Cited by 55 · see citing works

Characterization of adenosine‐uridine‐rich RNA binding factors

Nakamaki, T., Imamura, J., Brewer, G., et al. (1995) · Journal of Cellular Physiology · doi:10.1002/jcp.1041650306 · Cited by 44 · see citing works

Characterization of cDNAs encoding the murine A + U-rich RNA-binding protein AUF1

Ehrenman, K., Long, L., Wagner, B. J., & Brewer, G. (1994) · Gene · doi:10.1016/0378-1119(94)90168-6 · Cited by 39 · see citing works

U-Rich Sequence-Binding Proteins (URBPs) Interacting with a 20-Nucleotide U-Rich Sequence in the 3′ Untranslated Region of c-fos mRNA May Be Involved in the First Step of c-fos mRNA Degradation

You, Y., Chen, C. A., & Shyu, A. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.7.2931-2940.1992 · Cited by 35 · see citing works

A compendium of RNA-binding motifs for decoding gene regulation

Ray, D., Kazan, H., Cook, K. B., Weirauch, M. T., Najafabadi, H. S., Li, X., Gueroussov, S., Albu, M., Zheng, H., Yang, A., et al. (2013) · Nature · doi:10.1038/nature12311 · Cited by 1,480 · see citing works

HuR and mRNA stability

Brennan, C. M., & Steitz*, J. A. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000854 · Cited by 1,095 · see citing works

Diverse molecular functions of Hu proteins

Hinman, M. N., & Lou, H. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8252-6 · Cited by 587 · see citing works

The neurogenetics of alternative splicing

Vuong, C. K., Black, D. L., & Zheng, S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.27 · Cited by 340 · see citing works

RNA Protein Interaction in Neurons

Darnell, R. B. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062912-114322 · Cited by 181 · see citing works

Iron drives T helper cell pathogenicity by promoting RNA-binding protein PCBP1-mediated proinflammatory cytokine production

Wang, Z., Yin, W., Zhu, L., Li, J., Yao, Y., Chen, F., Sun, M., Zhang, J., Shen, N., Song, Y., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.05.008 · Cited by 156 · see citing works

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure

Eom, T., Zhang, C., Wang, H., Lay, K., Fak, J., Noebels, J. L., & Darnell, R. B. (2013) · eLife · doi:10.7554/elife.00178 · Cited by 118 · see citing works

Identification of the NAD+-Binding Fold of Glyceraldehyde-3-Phosphate Dehydrogenase as a Novel RNA-Binding Domain

Nagy, E., Henics, T., Eckert, M., Miseta, A., Lightowlers, R. N., & Kellermayer, M. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3246 · Cited by 99 · see citing works

ELAV inhibits 3′-end processing to promote neural splicing of <i>ewg</i> pre-mRNA

Soller, M., & White, K. (2003) · Genes &amp; Development · doi:10.1101/gad.1106703 · Cited by 89 · see citing works

IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence

Datta, S., Novotny, M., Pavicic, P. G., Zhao, C., Herjan, T., Hartupee, J., & Hamilton, T. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902423 · Cited by 82 · see citing works

Evidence for 3′ Untranslated Region-Dependent Autoregulation of the Drosophila Gene Encoding the Neuronal Nuclear RNA-Binding Protein ELAV

Samson, M.-L. (1998) · Genetics · doi:10.1093/genetics/150.2.723 · Cited by 51 · see citing works

Cyclic nucleotide regulation of Na+/glucose cotransporter (SGLT1) mRNA stability

Lee, W. Y., Loflin, P., Clancey, C. J., Peng, H., & Lever, J. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005040200 · Cited by 26 · see citing works

The Identification Zoo: Meanings of Identification in Econometrics

Lewbel, A. (2019) · Journal of Economic Literature · doi:10.1257/jel.20181361 · Cited by 159 · see citing works

[Identification based on medical findings].

Krompecher, T., Brandt-Casadevall, C., & Hr, G. (1988) · PubMed

Problems and Solutions of the Socialization of Identification Agencies

Jiang, T. (2009)

Development of Neutralization Assay using Murine Leukemia Virus (MuLV) Pseudotyped with Japanese encephalitis Virus (JEV) env Gene

Lee, H. J., Min, K.-I., Park, N., et al. (2007) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2007.37.1.23

A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

Bredenbeek, P. J., Molenkamp, R., Spaan, W. J. M., Deubel, V., Marianneau, P., Salvato, M. S., Moshkoff, D. A., Zapata, J. C., Tikhonov, I., Patterson, J. L., et al. (2006) · Virology · doi:10.1016/j.virol.2005.12.001 · Cited by 128 · see citing works