Preferential Incorporation of G Opposite Template T by the Low-Fidelity Human DNA Polymerase ι

Genetical Implications of the Structure of Deoxyribonucleic Acid

Watson, J. D., & Crick, F. H. C. (1953) · Nature · doi:10.1038/171964b0 · Cited by 2,196

Genetical Implications of the Structure of Deoxyribonucleic Acid

Watson, J. D., & Crick, F. H. C. (2017) · Klassische Texte der Wissenschaft · doi:10.1007/978-3-662-47150-0_5 · Cited by 1,310

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S., Takio, K., & Hanaoka, F. (1999) · Nature · doi:10.1038/21447 · Cited by 1,292

Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

Kubota, Y., Nash, R. A., Klungland, A., Schär, P., Barnes, D. E., & Lindahl, T. L. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01056.x · Cited by 776

Efficient Bypass of a Thymine-Thymine Dimer by Yeast DNA Polymerase, Polη

Johnson, R. E., Prakash, S., & Prakash, L. (1999) · Science · doi:10.1126/science.283.5404.1001 · Cited by 736

hRAD30 Mutations in the Variant Form of Xeroderma Pigmentosum

Johnson, R. E., Kondratick, C. M., Prakash, S., & Prakash, L. (1999) · Science · doi:10.1126/science.285.5425.263 · Cited by 732

Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase ζ

Nelson, J. R., Lawrence, C. W., & Hinkle, D. C. (1996) · Science · doi:10.1126/science.272.5268.1646 · Cited by 660

Deoxycytidyl transferase activity of yeast REV1 protein

Nelson, J. R., Lawrence, C. W., & Hinkle, D. C. (1996) · Nature · doi:10.1038/382729a0 · Cited by 583

UmuD′ 2 C is an error-prone DNA polymerase, Escherichia coli pol V

Tang, M., Shen, X., Frank, E. G., O’Donnell, M. E., Woodgate, R., & Goodman, M. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.8919 · Cited by 537

The dinB Gene Encodes a Novel E. coli DNA Polymerase, DNA Pol IV, Involved in Mutagenesis

Wagner, J. E., Grúz, P., Kim, S.-R., Yamada, M., Matsui, K., Fuchs, R. P., & Nohmi, T. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80376-7 · Cited by 474

EUKARYOTIC TRANSLESION SYNTHESIS DNA POLYMERASES: Specificity of Structure and Function

Prakash, S., Johnson, R. E., & Prakash, L. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133250 · Cited by 1,020

DNA Replication Fidelity

Kunkel, T. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.r400006200 · Cited by 754

Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes

Goodman, M. F. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.083101.124707 · Cited by 727

Y-family DNA polymerases and their role in tolerance of cellular DNA damage

Sale, J. E., Lehmann, A. R., & Woodgate, R. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3289 · Cited by 665

Crystal Structure of a Y-Family DNA Polymerase in Action

Ling, H., Boudsocq, F., Woodgate, R., & Yang, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00515-3 · Cited by 610

What a difference a decade makes: Insights into translesion DNA synthesis

Yang, W., & Woodgate, R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704219104 · Cited by 380

Active Site Tightness and Substrate Fit in DNA Replication

Kool, E. T. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135453 · Cited by 350

Eukaryotic DNA Polymerases: Proposal for a Revised Nomenclature

Burgers, P., Koonin, E. V., Bruford, E. A., Blanco, L., Burtis, K. C., Christman, M. F., Copeland, W. C., Friedberg, E. C., Hanaoka, F., Hinkle, D. C., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r100056200 · Cited by 337

Translesion DNA Polymerases

Goodman, M. F., & Woodgate, R. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a010363 · Cited by 317

Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing

Nair, D. T., Johnson, R. E., Prakash, S., Prakash, L., & Aggarwal, A. K. (2004) · Nature · doi:10.1038/nature02692 · Cited by 309

Rev1 Employs a Novel Mechanism of DNA Synthesis Using a Protein Template

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., & Aggarwal, A. K. (2005) · Science · doi:10.1126/science.1116336 · Cited by 249

Translesion DNA polymerases in eukaryotes: what makes them tick?

Vaisman, A., & Woodgate, R. (2017) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2017.1291576 · Cited by 261

Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta

Boudsocq, F. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.22.4607 · Cited by 232

trans-Lesion Synthesis Past Bulky Benzo[a]pyrene Diol Epoxide N2-dG and N6-dA Lesions Catalyzed by DNA Bypass Polymerases

Rechkoblit, O., Zhang, Y., Guo, D., Wang, Z., Amin, S., Krzeminski, J., Louneva, N., & Geacintov, N. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201167200 · Cited by 200

Crystal Structure of a DinB Lesion Bypass DNA Polymerase Catalytic Fragment Reveals a Classic Polymerase Catalytic Domain

Zhou, B.-L., Pata, J. D., & Steitz, T. A. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00310-0 · Cited by 198

5'-Deoxyribose Phosphate Lyase Activity of Human DNA Polymerase ɩ in Vitro

Bębenek, K., Tissier, A., Frank, E. G., McDonald, J. P., Prasad, R., Wilson, S. H., Woodgate, R., & Kunkel, T. A. (2001) · Science · doi:10.1126/science.1058386 · Cited by 197

Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

Haracska, L., Johnson, R. E., Unk, I., Phillips, B. B., Hurwitz, J., Prakash, L., & Prakash, S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.261560798 · Cited by 193

Localization of DNA polymerases η and ι to the replication machinery is tightly co‐ordinated in human cells

Kannouche, P. L., de Henestrosa, A. R. F., Coull, B. J., Vidal, A. E., Gray, C., Zicha, D., Woodgate, R., & Lehmann, A. R. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf618 · Cited by 193

Error-Prone DNA Polymerases: When Making a Mistake is the Only Way to Get Ahead

Rattray, A. J., & Strathern, J. N. (2003) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.042203.132748 · Cited by 182

An Overview of Y-Family DNA Polymerases and a Case Study of Human DNA Polymerase η

Yang, W. (2014) · Biochemistry · doi:10.1021/bi500019s · Cited by 183

129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

McDonald, J. P., Frank, E. G., Plosky, B. S., Rogozin, I. B., Masutani, C., Hanaoka, F., Woodgate, R., & Gearhart, P. J. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030767 · Cited by 172

Error rate and specificity of human and murine DNA polymerase η

Matsuda, T., Bebenek, K., Masutani, C., Rogozin, I. B., Hanaoka, F., & Kunkel, T. A. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4937 · Cited by 170

Structural Insights into the Origins of DNA Polymerase Fidelity

Beard, W. A., & Wilson, S. H. (2003) · Structure · doi:10.1016/s0969-2126(03)00051-0 · Cited by 157

Damage repair DNA polymerases Y

Yang, W. (2003) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(02)00003-9 · Cited by 152

Response of human DNA polymerase iota to DNA lesions

Zhang, Y. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.4.928 · Cited by 150

Y-family DNA polymerases in mammalian cells

Guo, C., Kosarek, J. N., Tang, T.-S., & Friedberg, E. C. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0024-4 · Cited by 147

Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion

Zhang, Y. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.7.1630 · Cited by 141

Efficiency of Correct Nucleotide Insertion Governs DNA Polymerase Fidelity

Beard, W. A., Shock, D. D., Vande Berg, B. J., & Wilson, S. H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m210036200 · Cited by 129

Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase ι

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., & Aggarwal, A. K. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1118 · Cited by 127

Translesion DNA synthesis polymerases in DNA interstrand crosslink repair

Ho, T. V., & Schärer, O. D. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20573 · Cited by 131

Functions of human DNA polymerases η, κ and ι suggested by their properties, including fidelity with undamaged DNA templates

Kunkel, T. A., Pavlov, Y. I., & Bebenek, K. (2003) · DNA Repair · doi:10.1016/s1568-7864(02)00224-0 · Cited by 125

Unique misinsertion specificity of polι may decrease the mutagenic potential of deaminated cytosines

Vaisman, A., & Woodgate, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.22.6520 · Cited by 129

Roles of DNA Polymerases in Replication, Repair, and Recombination in Eukaryotes

Pavlov, Y. I., Shcherbakova, P. V., & Rogozin, I. B. (2006) · International Review of Cytology · doi:10.1016/s0074-7696(06)55002-8 · Cited by 123

Human DNA Polymerase ι Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., & Aggarwal, A. K. (2005) · Structure · doi:10.1016/j.str.2005.08.010 · Cited by 123

Biochemical, Structural, and Physiological Characterization of Terminal Deoxynucleotidyl Transferase

Fowler, J. D., & Suo, Z. (2006) · Chemical Reviews · doi:10.1021/cr040445w · Cited by 119

Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase η during copying of a mouse immunoglobulin κ light chain transgene

Pavlov, Y. I., Rogozin, I. B., Galkin, A. P., Aksenova, A. Y., Hanaoka, F., Rada, C., & Kunkel, T. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.152126799 · Cited by 120

DNA Damage Control by Novel DNA Polymerases: Translesion Replication and Mutagenesis

Livneh, Z. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r100019200 · Cited by 119

Altered DNA Polymerase ι Expression in Breast Cancer Cells Leads to a Reduction in DNA Replication Fidelity and a Higher Rate of Mutagenesis

Jin, Y., Chen, Z., Liu, Y., Hickey, R. J., & Malkas, L. H. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0603 · Cited by 115

Increased Catalytic Activity and Altered Fidelity of Human DNA Polymerase ι in the Presence of Manganese

Frank, E. G., & Woodgate, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702159200 · Cited by 115

Quantitative measurement of translesion replication in human cells: Evidence for bypass of abasic sites by a replicative DNA polymerase

Avkin, S., Adar, S., Blander, G., & Livneh, Z. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.062038699 · Cited by 112

Replication of damaged DNA in mammalian cells: new solutions to an old problem

Lehmann, A. R. (2002) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(02)00227-0 · Cited by 112

Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelity

Zhang, Y. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.21.4147 · Cited by 109

Activities of human DNA polymerase κ in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion

Zhang, Y. (2002) · DNA repair · doi:10.1016/s1568-7864(02)00055-1 · Cited by 108

Human DNA polymerase iota protects cells against oxidative stress

Lajus, T. B. P., Nakajima, S., Zlatanou, A., Despras, E., Couvé, S., Ishchenko, A. A., Sarasin, A. R., Yasui, A., & Kannouche, P. L. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.210 · Cited by 115

Translesion synthesis by the UmuC family of DNA polymerases

Wang, Z. (2001) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(01)00089-1 · Cited by 97

Translesion synthesis by yeast DNA polymerase zeta from templates containing lesions of ultraviolet radiation and acetylaminofluorene

Guo, D. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.13.2875 · Cited by 98

Addendum

Kannouche, P. L., de Henestrosa, A. R. F., Coull, B. J., Vidal, A. E., Gray, C., Zicha, D., Woodgate, R., & Lehmann, A. R. (2003) · The EMBO Journal · doi:10.1093/emboj/7595006 · Cited by 98

DNA polymerases and human diseases

Sweasy, J. B., Lauper, J. M., & Eckert, K. A. (2006) · Radiation Research · doi:10.1667/rr0706.1 · Cited by 93

Analysis of specialized DNA polymerases expression in human gliomas: association with prognostic significance

Wang, H., Wu, W., Wang, H., Wang, S., Chen, Y., Zhang, X., Yang, H. J., Zhao, S., Ding, H., & Lu, D. (2010) · Neuro-Oncology · doi:10.1093/neuonc/nop074 · Cited by 93

Proliferating Cell Nuclear Antigen-dependent Coordination of the Biological Functions of Human DNA Polymerase ι

Vidal, A. E., Kannouche, P. L., Podust, V. N., Yang, W., Lehmann, A. R., & Woodgate, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406511200 · Cited by 90

Variations on a theme: Eukaryotic Y-family DNA polymerases

Washington, M. T., Carlson, K. D., Freudenthal, B., & Pryor, J. M. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2009.07.004 · Cited by 90

Highly Frequent Frameshift DNA Synthesis by Human DNA Polymerase μ

Zhang, Y., Wu, X., Yuan, F., Xie, Z., & Wang, Z. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.23.7995-8006.2001 · Cited by 83

Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass

Boudsocq, F. (2002) · DNA Repair · doi:10.1016/s1568-7864(02)00019-8 · Cited by 79

Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases

Zhao, L., & Washington, M. T. (2017) · Genes · doi:10.3390/genes8010024 · Cited by 82

Two-step error-prone bypass of the (+)- and (−)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases η and κ

Zhang, Y., Wu, X., Guo, D., Rechkoblit, O., Geacintov, N. E., & Wang, Z. (2002) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(02)00249-x · Cited by 78

BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells

Słupianek, A., Nowicki, M. O., Koptyra, M., & Skórski, T. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.10.005 · Cited by 80

Kinetic Evidence for Inefficient and Error-prone Bypass across Bulky N-Guanine DNA Adducts by Human DNA Polymerase ι

Choi, J., & Guengerich, F. P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600112200 · Cited by 74

Lesion Bypass of N2-Ethylguanine by Human DNA Polymerase ι

Pence, M. G., Blans, P., Zink, C. N., Hollis, T., Fishbein, J. C., & Perrino, F. W. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m807296200 · Cited by 73

Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota

Frank, E. G. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf643 · Cited by 72

Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota

Kirouac, K. N., & Ling, H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1013909108 · Cited by 72

Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase ι

Johnson, R. E., Prakash, L., & Prakash, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503859102 · Cited by 71

Structural basis of error‐prone replication and stalling at a thymine base by human DNA polymerase ι

Kirouac, K. N., & Ling, H. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.122 · Cited by 71

Mechanistic Comparison of High-Fidelity and Error-Prone DNA Polymerases and Ligases Involved in DNA Repair

Showalter, A. K., Lamarche, B. J., Bakhtina, M., Su, M., Tang, K., & Tsai, M. (2006) · Chemical Reviews · doi:10.1021/cr040487k · Cited by 71

Translesion DNA Polymerases and Cancer

Makridakis, N. M., & Reichardt, J. K. V. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00174 · Cited by 70

Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

Poltoratsky, V. P., Woo, C. J., Tippin, B. L., Martín, A., Goodman, M. F., & Scharff, M. D. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.141222198 · Cited by 69

Lesion Bypass Activities of Human DNA Polymerase μ

Zhang, Y., Wu, X., Guo, D., Rechkoblit, O., Taylor, J., Geacintov, N. E., & Wang, Z. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207297200 · Cited by 68

Functions of Eukaryotic DNA Polymerases

Shcherbakova, P. V., Bębenek, K., & Kunkel, T. A. (2003) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2003.8.re3 · Cited by 69

The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability

Sharma, S., Helchowski, C. M., & Canman, C. E. (2012) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2012.11.002 · Cited by 71

Making choices: DNA replication fork recovery mechanisms

Kondratick, C. M., Washington, M. T., & Spies, M. (2020) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2020.10.001 · Cited by 75

Pre-Steady-State Kinetic Studies of the Fidelity and Mechanism of Polymerization Catalyzed by Truncated Human DNA Polymerase λ

Fiala, K. A., Abdel-Gawad, W., & Suo, Z. (2004) · Biochemistry · doi:10.1021/bi049975c · Cited by 66

Localization of the Deoxyribose Phosphate Lyase Active Site in Human DNA Polymerase ι by Controlled Proteolysis

Prasad, R., Bębenek, K., Hou, E. W., Shock, D. D., Beard, W. A., Woodgate, R., Kunkel, T. A., & Wilson, S. H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305399200 · Cited by 66

An Incoming Nucleotide Imposes an anti to syn Conformational Change on the Templating Purine in the Human DNA Polymerase-ι Active Site

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., & Aggarwal, A. K. (2006) · Structure · doi:10.1016/j.str.2006.01.010 · Cited by 65

Altered nucleotide misinsertion fidelity associated with polι‐dependent replication at the end of a DNA template

Frank, E. G., Tissier, A., McDonald, J. P., Rapić‐Otrin, V., Zeng, X., Gearhart, P. J., & Woodgate, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.11.2914 · Cited by 62

REV3L 3′UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility

Zhang, S., Chen, H., Zhao, X., Cao, J., Tong, J., Lü, J., Wu, W., Shen, H., Wei, Q., & Lu, D. (2012) · Oncogene · doi:10.1038/onc.2012.32 · Cited by 61

Synthesis of Site-Specific DNA–Protein Conjugates and Their Effects on DNA Replication

Yeo, J. E., Wickramaratne, S., Khatwani, S. L., Wang, Y.-C., Vervacke, J. S., Distefano, M. D., & Tretyakova, N. Y. (2014) · ACS Chemical Biology · doi:10.1021/cb5001795 · Cited by 63

A Single Domain in Human DNA Polymerase ι Mediates Interaction with PCNA: Implications for Translesion DNA Synthesis

Haracska, L., Acharya, N., Unk, I., Johnson, R. E., Hurwitz, J., Prakash, L., & Prakash, S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.3.1183-1190.2005 · Cited by 60

Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase ι

Vaisman, A., Frank, E. G., Iwai, S., Ohashi, E., Ohmori, H., Hanaoka, F., & Woodgate, R. (2003) · DNA repair · doi:10.1016/s1568-7864(03)00094-6 · Cited by 59

Mutagenesis and Repair Induced by the DNA Advanced Glycation End Product N 2 -1-(Carboxyethyl)-2′-deoxyguanosine in Human Cells

Tamae, D., Lim, P. P., Wuenschell, G. E., & Termini, J. S. (2011) · Biochemistry · doi:10.1021/bi101933p · Cited by 58

Yeast and Human Translesion DNA Synthesis Polymerases: Expression, Purification, and Biochemical Characterization

Johnson, R. E., Prakash, L., & Prakash, S. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)08024-4 · Cited by 57

Evolution of the two-step model for UV-mutagenesis

Woodgate, R. (2001) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(00)00076-8 · Cited by 56

Human DNA Polymerase ι Utilizes Different Nucleotide Incorporation Mechanisms Dependent upon the Template Base

Washington, M. T., Johnson, R. E., Prakash, L., & Prakash, S. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.24.2.936-943.2004 · Cited by 55

Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

Wolfle, W. T., Washington, M. T., Kool, E. T., Spratt, T. E., Helquist, S. A., Prakash, L., & Prakash, S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.16.7137-7143.2005 · Cited by 55

The role of polycyclic aromatic hydrocarbon–DNA adducts in inducing mutations in mouse skin

Chakravarti, D., Venugopal, D., Mailander, P. C., Meza, J. L., Higginbotham, S. M., Cavalieri, E. L., & Rogan, E. G. (2007) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2007.08.007 · Cited by 60

Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity

Akbari, M., Peña-Dı́az, J., Andersen, S. B., Liabakk, N., Otterlei, M., & Krokan, H. E. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.04.002 · Cited by 53

Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase ι

Pence, M. G., Choi, J., Egli, M., & Guengerich, F. P. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.183665 · Cited by 53

Genetic linkage between Polι deficiency and increased susceptibility to lung tumors in mice

Lee, G., & Matsushita, H. (2005) · Cancer Science · doi:10.1111/j.1349-7006.2005.00042.x · Cited by 51

Human DNA Polymerase ι Promiscuous Mismatch Extension

Vaisman, A., Tissier, A., Frank, E. G., Goodman, M. F., & Woodgate, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102694200 · Cited by 51

Pol ι Is a Candidate for the Mouse Pulmonary Adenoma Resistance 2 Locus, a Major Modifier of Chemically Induced Lung Neoplasia

Wang, M., Devereux, T. R., Vikis, H. G., McCulloch, S. D., Holliday, W. M., Anna, C. H., Wang, Y., Bębenek, K., Kunkel, T. A., Guan, K., et al. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3080 · Cited by 50

Generation of mutator mutants during carcinogenesis

Venkatesan, R. N., Bielas, J. H., & Loeb, L. A. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.10.012 · Cited by 49

Translesion synthesis DNA polymerases and control of genome stability

Polina, V. S. (2006) · Frontiers in bioscience · doi:10.2741/1985 · Cited by 46

Polymerase iota - an odd sibling among Y family polymerases

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A Highly Effective Nonpolar Isostere of Deoxyguanosine: Synthesis, Structure, Stacking, and Base Pairing

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polι-dependent lesion bypass in vitro

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Preferential Incorporation of G Opposite Template T by the

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