Improving infant sleep and maternal mental health: a cluster randomised trial
Open accessAbstract
OBJECTIVES: To determine whether a community-delivered intervention targeting infant sleep problems improves infant sleep and maternal well-being and to report the costs of this approach to the healthcare system. DESIGN: Cluster randomised trial. SETTING: 49 Maternal and Child Health (MCH) centres (clusters) in Melbourne, Australia. PARTICIPANTS: 328 mothers reporting an infant sleep problem at 7 months recruited during October-November 2003. INTERVENTION: Behavioural strategies delivered over individual structured MCH consultations versus usual care. MAIN OUTCOME MEASURES: Maternal report of infant sleep problem, depression symptoms (Edinburgh Postnatal Depression Scale (EPDS)), and SF-12 mental and physical health scores when infants were 10 and 12 months old. Costs included MCH sleep consultations, other healthcare services and intervention costs. RESULTS: Prevalence of infant sleep problems was lower in the intervention than control group at 10 months (56% vs 68%; adjusted OR 0.58 (95% CI: 0.36 to 0.94)) and 12 months (39% vs 55%; adjusted OR 0.50 (0.31 to 0.80)). EPDS scores indicated less depression at 10 months (adjusted mean difference -1.4 (-2.3 to -0.4) and 12 months (-1.7 (-2.6 to -0.7)). SF-12 mental health scores indicated better health at 10 months (adjusted mean difference 3.7 (1.5 to 5.8)) and 12 months (3.9 (1.8 to 6.1)). Total mean costs including intervention design, delivery and use of non-MCH nurse services were 96.93 pounds sterling and 116.79 pounds sterling per intervention and control family, respectively. CONCLUSIONS: Implementing this sleep intervention may lead to health gains for infants and mothers and resource savings for the healthcare system. TRIAL REGISTRATION: Current Controlled Trial Registry, number ISRCTN48752250 [controlled-trials.com] (registered November 2004).
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Early childhood sleep problems are associated with poor developmental outcomes across neurocognitive, social-emotional, physical health, and family functioning domains.
“early childhood sleep problems are associated with a number of poor developmental outcomes across neurocognitive [4,5], social-emotional [6-9], physical health [10,11], and family functioning domains [12-15]”
From Benefits of a bedtime routine in young children: Sleep, development, and beyond. (2018) · cites this paper as [12]
The introduction (section M; page unavailable) links infant sleep problems with poor maternal health and links maternal depression with poorer mother-child relationships. The Discussion likewise says mothers reporting infant sleep problems suffer poorer mental health. These passages support an association with maternal well-being, but do not establish the broader family-functioning outcome attributed to this source; the other outcome domains are attached to different citations in the citing sentence. (LLM, conf=0.83)
Experimental — accuracy not yet measuredDisrupted parental sleep, presenting as post-partum fatigue and perceived as problematic infant sleep, is related to increased symptoms of depression and anxiety among new mothers and fathers.
“Disrupted parental sleep, presenting as post-partum fatigue and perceived as problematic infant sleep, is related to increased symptoms of depression and anxiety among new mothers and fathers.”
From Development and evaluation of ‘Sleep, Baby & You’—An approach to supporting parental well-being and responsive infant caregiving (2020) · cites this paper as [5]
The introduction and Discussion link reported infant sleep problems with poorer maternal mental health, and the Maternal well-being section reports measures of mothers’ sleep and depression symptoms. The paper does not establish the claimed relationship for fathers or address anxiety symptoms or postpartum fatigue as such. Page numbers are unavailable in our copy. (LLM, conf=0.88)
Experimental — accuracy not yet measuredParental fatigue and sleep disruption can lead to the development of mood disorders in both mothers and fathers and exacerbate existing mental and physical health problems.
“There is also ample evidence that parental fatigue and sleep disruption can lead to the development of mood disorders in both mothers and fathers [3,5–8] and exacerbate existing mental and physical health problems [9,10].”
From Development and evaluation of ‘Sleep, Baby & You’—An approach to supporting parental well-being and responsive infant caregiving (2020) · cites this paper as [5]
The Discussion (page unavailable) links infant sleep problems with poorer maternal mental health, and the Maternal well-being results report lower depression-symptom scores after an infant sleep intervention. The paper does not establish that parental fatigue causes new mood disorders, study fathers’ mood, or show that sleep disruption exacerbates existing mental or physical health problems. (LLM, conf=0.87)
Experimental — accuracy not yet measured
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Self-citation
- Authors
- Hiscock, H., Bayer, J., Gold, L., Hampton, A., Ukoumunne, O. C., & Wake, M.
- Affiliations
- Royal Children's Hospital (AU)
- Murdoch Children's Research Institute (AU)
- La Trobe University (AU)
- Corresponding author
- Hiscock, H.
- Venue
- Archives of Disease in Childhood
- Publisher
- BMJ
- Published
- 2007-03-22
- Volume
- 92
- Issue
- 11
- Pages
- 952-958
- ISSN
- 0003-9888 (ISSN-L)
- 1468-2044
- PMC
- PMC2083609
- OpenAlex
- W2166810018
- Cited by
- 188
- References
- 39
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 19 · 2023: 6 · 2022: 9 · 2021: 13 · 2020: 13 · 2019: 10 · 2018: 10 · 2017: 11 · 2016: 10 · 2015: 15 · 2014: 5 · 2013: 6 · 2012: 18
- FWCI
- 7.08
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Archives of Disease in Childhood (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- Pratt Foundation
- Medical Research Council
- National Health and Medical Research Council (237120)
- Topics
- Health Sciences › Health Professions › Pharmacy › Infant Health and Development
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- infant sleep problems, maternal mental health, postpartum depression, behavioral interventions, health care costs, infant sleep, maternal depression
- MeSH terms
- Australia, Behavior Therapy, Costs and Cost Analysis, Female, Humans, Infant, Infant Care, Sleep Initiation and Maintenance Disorders, Male, Mental Health, Mother-Child Relations, Mothers, Patient Satisfaction, Infant Behavior, Depression, Postpartum
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