The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Delivery by caesarean section and risk of obesity in preschool age children: a prospective cohort study
Open accessAbstract
Objective: To examine whether delivery by caesarean section is a risk factor for childhood obesity. Design: Prospective prebirth cohort study (Project Viva). Setting: Eight outpatient multi-specialty practices based in the Boston, Massachusetts area. Participants: We recruited women during early pregnancy between 1999 and 2002, and followed their children after birth. We included 1255 children with body composition measured at 3 years of age. Main outcome measures: BMI score, obesity (BMI for age and sex ≥95th percentile), and sum of triceps plus subscapular skinfold thicknesses at 3 years of age. Results: 284 children (22.6%) were delivered by caesarean section. At age 3, 15.7% of children delivered by caesarean section were obese compared with 7.5% of children born vaginally. In multivariable logistic and linear regression models adjusting for maternal prepregnancy BMI, birth weight, and other covariates, birth by caesarean section was associated with a higher odds of obesity at age 3 (OR 2.10, 95% CI 1.36 to 3.23), higher mean BMI z-score (0.20 units, 95% CI 0.07 to 0.33), and higher sum of triceps plus subscapular skinfold thicknesses (0.94 mm, 95% CI 0.36 to 1.51). Conclusions: Infants delivered by caesarean section may be at increased risk of childhood obesity. Further studies are needed to confirm our findings and to explore mechanisms underlying this association.
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An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
Human gut microbes associated with obesity
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785
Development of the Human Infant Intestinal Microbiota
Palmer, C., Bik, E. M., DiGiulio, D. B., Relman, D. A., & Brown, P. O. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050177 · Cited by 2,877
Mode of delivery affects the bacterial community in the newborn gut
Biasucci, G., Rubini, M., Riboni, S., Morelli, L., Bessi, E., & Retetangos, C. (2010) · Early Human Development · doi:10.1016/j.earlhumdev.2010.01.004 · Cited by 507
Influence of mode of delivery on gut microbiota composition in seven year old children: Table 1
Salminen, S., Gibson, G. R., McCartney, A. L., & Isolauri, E. (2004) · Gut · doi:10.1136/gut.2004.041640 · Cited by 435
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Cox, L. M., Yamanishi, S., Sohn, J., Alekseyenko, A. V., Leung, J. M., Cho, I., Kim, S. G., Li, H., Gao, Z., Mahana, D., et al. (2014) · Cell · doi:10.1016/j.cell.2014.05.052 · Cited by 1,859
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Mancabelli, L., Tarracchini, C., Milani, C., Lugli, G. A., Fontana, F., Turroni, F., van Sinderen, D., & Ventura, M. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.08.028 · Cited by 39
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Metadata
- Authors
- Huh, S. Y., Rifas-Shiman, S. L., Zera, C. A., Edwards, J. W. R., Oken, E., Weiss, S. T., & Gillman, M. W.
- Venue
- Archives of Disease in Childhood
- Publisher
- BMJ
- Published
- 2012-05-23
- Volume
- 97
- Issue
- 7
- Pages
- 610-616
- ISSN
- 0003-9888 (ISSN-L)
- 1468-2044
- OpenAlex
- W2159619567
- Cited by
- 293
- References
- 5
- FWCI
- 23.43
- Type
- journal article
- Language
- en
- Open access
- green
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