Cited by 435Gut microbiota and healthInfant Nutrition and HealthMaternal and Perinatal Health Interventions

Influence of mode of delivery on gut microbiota composition in seven year old children: Table 1

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Salminen, S, Gibson, G R, McCartney, A L, Isolauri, E·2004·Gut

Abstract

Intestinal microbiota development begins immediately following birth.1 The composition of the infant’s evolving microbiota is initially defined by the mother, the source of the newborn’s first microbial inoculum. Colonising bacteria rapidly adapt to breast milk and epithelial mucins as sources of nutrients. The prevalence of caesarean section delivery in Western countries is increasing. Caesarean born babies are deprived of contact with the maternal/vaginal microbiota and the first exposure is characterised by a lack of strict anaerobes and the presence of facultative anaerobes such as Clostridium species.2 Caesarean born infants have a more slowly diversifying microbiota, with differences reported from normally born infants, even after six months of age. Aberrancies in early microbiota acquisition can affect immunophysiological development with a heightened disease risk.2,3 This …

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  • There are long-term compositional differences in gut microbiota by mode of birth, with differences observed up until age seven.

    “The result is long-term compositional differences in gut microbiota by mode of birth20–24, with differences observed up until age seven24.”

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Research works printed but not linked: 3

  1. Sarela AI, Hick DG, Verbeke CS, et al. Persistent acid and bile reflux in asymptomatic patients with Barrett's esophagus on proton pump inhibitor therapy. Arch Surg 2004 (in press).
  2. Kallioma ¨ki M, Kirjavainen P, Eerola E, et al. Distinct patterns of neonatal gut microflora in infants developing or not developing atopy. J Allergy Clin Immunol 2001;107:129-34.
  3. Ramji A, Owen DA, Erb SR, et al. Post-liver transplant Crohn's disease: graft tolerance but not self-tolerance? Digest Dis Sci 2002;47:522-7.

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Authors
Salminen, S., Gibson, G. R., McCartney, A. L., & Isolauri, E.
Affiliations
  • University of Turku (FI)
  • University of Reading (GB)
Corresponding author
Salminen, S
Venue
Gut
Publisher
BMJ
Published
2004-08-11
Volume
53
Issue
9
Pages
1388.2-1389
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2171217592
Cited by
435
References
31
Citations by year
2026: 7 · 2025: 11 · 2024: 20 · 2023: 20 · 2022: 29 · 2021: 29 · 2020: 35 · 2019: 39 · 2018: 21 · 2017: 35 · 2016: 37 · 2015: 28 · 2014: 24 · 2013: 13 · 2012: 21
FWCI
2.01
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Gut (publishedVersion, other-oa)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
  • Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
Keywords
mode of delivery, gut microbiota, cesarean section, vaginal microbiota, breast milk, Clostridium, anaerobic bacteria, early life microbial exposure
MeSH terms
Asthma, Bacteria, Cesarean Section, Child, Dermatitis, Atopic, Humans, Intestines, Delivery, Obstetric

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