Human glaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortex

The unbiased estimation of number and sizes of arbitrary particles using the disector

Sterio, D. C. (1984) · Journal of Microscopy · doi:10.1111/j.1365-2818.1984.tb02501.x · Cited by 2,533

Optic Nerve Damage in Human Glaucoma

Quigley, H. A. (1981) · Archives of Ophthalmology · doi:10.1001/archopht.1981.03930010635009 · Cited by 1,246

Relationship Between Intraocular Pressure and Primary Open Angle Glaucoma Among White and Black Americans

Sommer, A. H. (1991) · Archives of Ophthalmology · doi:10.1001/archopht.1991.01080080050026 · Cited by 1,178

Optic Nerve Damage in Human Glaucoma

Quigley, H. A. (1982) · Archives of Ophthalmology · doi:10.1001/archopht.1982.01030030137016 · Cited by 1,177

Effects of retinal ganglion cell loss on magno-, parvo-, koniocellular pathways in the lateral geniculate nucleus and visual cortex in glaucoma

Yücel, Y. (2003) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(03)00026-0 · Cited by 384

The representation of the visual field in the lateral geniculate nucleus of Macaca mulatta

Malpeli, J. G., & Baker, F. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901610407 · Cited by 312

Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma

Yücel, Y. H. (2000) · Archives of Ophthalmology · doi:10.1001/archopht.118.3.378 · Cited by 305

Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus.

Weber, A. J., Chen, H., Hubbard, W. C., & Kaufman, P. L. P. (2000) · PubMed · Cited by 265

The Human Nervous System: An Anatomical Viewpoint

Harrison, T. J. (1972) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1972.tb88233.x · Cited by 244

Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma.

Yücel, Y. H., Zhang, Q., Weinreb, R. N., Kaufman, P. L., & Gupta, N. (2001) · PubMed · Cited by 214

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age‐Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

Nita, M., & Grzybowski, A. E. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/3164734 · Cited by 1,510

The molecular basis of retinal ganglion cell death in glaucoma

Almasieh, M., Wilson, A. M., Morquette, B., Vargas, J. L. C., & Polo, A. D. (2011) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2011.11.002 · Cited by 990

Definition of glaucoma: clinical and experimental concepts

Casson, R. J., Chidlow, G., Wood, J. P. M., Crowston, J. G., & Goldberg, I. (2012) · Clinical and Experimental Ophthalmology · doi:10.1111/j.1442-9071.2012.02773.x · Cited by 510

The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma.

Ramirez, A. I., de Hoz, R., Salobrar-Garcia, E., Salazar, J. J., Rojas, B., Ajoy, D., López-Cuenca, I., Rojas, P., Triviño, A., & Ramírez, J. M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00214 · Cited by 466

Inflammation in Glaucoma: From the back to the front of the eye, and beyond

Baudouin, C., Kolko, M., Parsadaniantz, S. M., & Messmer, E. S. B. M. (2020) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100916 · Cited by 480

Glaucoma as a neurodegenerative disease

Gupta, N., & Yücel, Y. H. (2007) · Current Opinion in Ophthalmology · doi:10.1097/icu.0b013e3280895aea · Cited by 430

What Is the Present Pathogenetic Concept of Glaucomatous Optic Neuropathy?

Flammer, J., & Mozaffarieh, M. (2007) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2007.08.012 · Cited by 316

Critical pathogenic events underlying progression of neurodegeneration in glaucoma

Calkins, D. J. (2012) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2012.07.001 · Cited by 305

Glaucoma: the retina and beyond

Davis, B. M., Crawley, L. A., Pahlitzsch, M., Javaid, F. Z., & Cordeiro, M. F. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1609-2 · Cited by 291

Contribution of Microglia‐Mediated Neuroinflammation to Retinal Degenerative Diseases

Madeira, M. H., Boia, R., Santos, P. F., Ambrósio, A. F., & Santiago, A. R. (2015) · Mediators of Inflammation · doi:10.1155/2015/673090 · Cited by 232

Mental stress as consequence and cause of vision loss: the dawn of psychosomatic ophthalmology for preventive and personalized medicine

Sabel, B. A., Wang, J., Cárdenas‐Morales, L., Faiq, M. A., & Heim, C. C. (2018) · The EPMA Journal · doi:10.1007/s13167-018-0136-8 · Cited by 242

Atrophy of the lateral geniculate nucleus in human glaucoma detected by magnetic resonance imaging

Gupta, N., Greenberg, G., de Tilly, L. N., Gray, B., Polemidiotis, M., & Yucel, Y. H. (2008) · British Journal of Ophthalmology · doi:10.1136/bjo.2008.138172 · Cited by 218

Changes in cortical grey matter density associated with long-standing retinal visual field defects

Boucard, C. C., Hernowo, A. T., Maguire, R. P., Jansonius, N. M., Roerdink, J. B. T. M., Hooymans, J. M. M., & Cornelissen, F. W. (2009) · Brain · doi:10.1093/brain/awp119 · Cited by 214

Optic Nerve and Optic Radiation Neurodegeneration in Patients with Glaucoma: In Vivo Analysis with 3-T Diffusion-Tensor MR Imaging

Garaci, F. G., Bolacchi, F., Cerulli, A., Melis, M., Spanò, A., Cedrone, C., Floris, R., Simonetti, G., & Nucci, C. (2009) · Radiology · doi:10.1148/radiol.2522081240 · Cited by 196

New insights in the pathogenesis and treatment of normal tension glaucoma

Mozaffarieh, M., & Flammer, J. (2012) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2012.10.001 · Cited by 164

Alzheimers Disease and Retinal Neurodegeneration

Guo, L., Duggan, J., & Cordeiro, M. F. (2010) · Current Alzheimer Research · doi:10.2174/156720510790274491 · Cited by 161

Neuroprotection in glaucoma – Is there a future role?

Baltmr, A., Duggan, J., Nizari, S., Salt, T. E., & Cordeiro, M. F. (2010) · Experimental Eye Research · doi:10.1016/j.exer.2010.08.009 · Cited by 156

Structural Brain Abnormalities in Patients with Primary Open-Angle Glaucoma: A Study with 3T MR Imaging

Chen, W. W., Wang, N., Cai, S., Fang, Z., Yu, M., Wu, Q., Tang, L., Guo, B., Feng, Y., Jonas, J. B., et al. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9893 · Cited by 155

Retinal tau pathology in human glaucomas

Gupta, N., Fong, J., Ang, L. C., & Yücel, Y. H. (2008) · Canadian Journal of Ophthalmology · doi:10.3129/i07-185 · Cited by 135

Resting-state functional MRI: Functional connectivity analysis of the visual cortex in primary open-angle glaucoma patients

Dai, H., Morelli, J. N., Ai, F., Yin, D., Hu, C., Xu, D., & Li, Y. (2012) · Human Brain Mapping · doi:10.1002/hbm.22079 · Cited by 130

Retinotopic organization of primary visual cortex in glaucoma: Comparing fMRI measurements of cortical function with visual field loss

Duncan, R. O., Sample, P. A., Weinreb, R. N., Bowd, C., & Zangwill, L. M. (2006) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2006.10.001 · Cited by 130

Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration

Yücel, Y. H., & Gupta, N. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)01132-1 · Cited by 129

Alzheimer’s Retinopathy: Seeing Disease in the Eyes

Mirzaei, N., Shi, H., Oviatt, M., Doustar, J., Rentsendorj, A., Fuchs, D.-T. S., Sheyn, J., Black, K. L., Koronyo, Y., & Koronyo‐Hamaoui, M. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00921 · Cited by 136

The Dysfunction of the Trabecular Meshwork During Glaucoma Course

Saccà, S. C., Pulliero, A., & Izzotti, A. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24826 · Cited by 130

Retinal biomarkers for Alzheimer’s disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

Czakó, C. N., Kovács, T., Ungvari, Z. I., Csiszár, A., Yabluchanskiy, A., Conley, S. M., Csípő, T., Lipécz, Á., Horváth, H., Sándor, G. L., et al. (2020) · GeroScience · doi:10.1007/s11357-020-00252-7 · Cited by 130

Glaucoma and the brain: Trans-synaptic degeneration, structural change, and implications for neuroprotection

Lawlor, M., Danesh-Meyer, H. V., Levin, L. A., Davagnanam, I., Vita, E. D., & Plant, G. T. (2017) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2017.09.010 · Cited by 123

Chronic ocular hypertension induces dendrite pathology in the lateral geniculate nucleus of the brain

Gupta, N., Ly, T., Zhang, Q., Kaufman, P. L., Weinreb, R. N., & Yücel, Y. H. (2007) · Experimental Eye Research · doi:10.1016/j.exer.2006.09.013 · Cited by 122

Visual Impairment in Alzheimer's Disease: A Critical Review

Kirby, E., Bandelow, S., & Hogervorst, E. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-080785 · Cited by 117

Voxel-Based Morphometry and Diffusion Tensor Imaging of the Optic Pathway in Primary Open-Angle Glaucoma: A Preliminary Study

Zikou, A. K., Kitsos, G., Tzarouchi, L. C., Astrakas, L. G., Alexiou, G. Α., & Argyropoulou, M. I. (2011) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2714 · Cited by 118

Cholinergic nervous system and glaucoma: From basic science to clinical applications

Faiq, M. A., Wollstein, G., Schuman, J. S., & Chan, K. C. (2019) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2019.06.003 · Cited by 127

Crocin prevents retinal ischaemia/reperfusion injury-induced apoptosis in retinal ganglion cells through the PI3K/AKT signalling pathway

Qi, Y., Chen, L., Zhang, L., Liu, W.-B., Chen, X.-Y., & Yang, X. (2012) · Experimental Eye Research · doi:10.1016/j.exer.2012.11.011 · Cited by 113

Neuroprotective agents in the management of glaucoma

Nucci, C., Martucci, A., Giannini, C., Morrone, L. A., Bagetta, G., & Mancino, R. (2018) · Eye · doi:10.1038/s41433-018-0050-2 · Cited by 111

Gene therapy and transplantation in CNS repair: The visual system

Harvey, A. R., Hu, Y. J., Leaver, S. G., Mellough, C., Park, K. K., Verhaagen, J., Plant, G. W., & Cui, Q. (2006) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2006.07.002 · Cited by 110

Alzheimer’s Disease and Glaucoma: Mechanistic Similarities and Differences

Ghiso, J. A. (2013) · Journal of Glaucoma · doi:10.1097/ijg.0b013e3182934af6 · Cited by 107

The Cell and Molecular Biology of Glaucoma: Axonopathy and the Brain

Calkins, D. J., & Horner, P. J. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9483i · Cited by 103

Neuroinflammation in Primary Open-Angle Glaucoma

Vernazza, S., Tirendi, S., Bassi, A. M., Traverso, C. E., & Saccà, S. C. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9103172 · Cited by 109

Detection of early neuron degeneration and accompanying glial responses in the visual pathway in a rat model of acute intraocular hypertension

Zhang, S., Wang, H., Lu, Q., Qing, G., Wang, N., Wang, Y., Li, S., Yang, D., & Yan, F. (2009) · Brain Research · doi:10.1016/j.brainres.2009.09.029 · Cited by 99

Automated Morphometry of the Visual Pathway in Primary Open-Angle Glaucoma

Hernowo, A. T., Boucard, C. C., Jansonius, N. M., Hooymans, J. M. M., & Cornelissen, F. W. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5682 · Cited by 100

Getting signals into the brain: visual prosthetics through thalamic microstimulation

Pezaris, J. S., & Eskandar, E. N. (2009) · Neurosurgical FOCUS · doi:10.3171/2009.4.focus0986 · Cited by 98

Age-related changes in the visual pathways: blame it on the axon

Calkins, D. J. (2013) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.13-12784 · Cited by 96

Animal Toxins as Therapeutic Tools to Treat Neurodegenerative Diseases

de Souza, J. M., Gonçalves, B. D. C., Gomez, M. V., Vieira, L. B., & Ribeiro, F. M. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00145 · Cited by 94

Early changes of brain connectivity in primary open angle glaucoma

Frezzotti, P., Giorgio, A., Toto, F., Leucio, A. D., & Stefano, N. D. (2016) · Human Brain Mapping · doi:10.1002/hbm.23330 · Cited by 96

Structural brain alterations in primary open angle glaucoma: a 3T MRI study

Wang, J., Li, T., Sabel, B. A., Chen, Z., Wen, H., Li, J., Xie, X., Yang, D., Chen, W., Wang, N., et al. (2016) · Scientific Reports · doi:10.1038/srep18969 · Cited by 92

Changes of Visual Pathway and Brain Connectivity in Glaucoma: A Systematic Review

Nuzzi, R., Dallorto, L., & Rolle, T. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00363 · Cited by 91

Axon injury signaling and compartmentalized injury response in glaucoma

Syc‐Mazurek, S. B., & Libby, R. T. (2019) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2019.07.002 · Cited by 92

Retinal Structures and Visual Cortex Activity are Impaired Prior to Clinical Vision Loss in Glaucoma

Murphy, M. C., Conner, I. P., Teng, C. Y., Lawrence, J. D., Safiullah, Z. N., Wang, B., Bilonick, R. A., Kim, S., Wollstein, G., Schuman, J. S., et al. (2016) · Scientific Reports · doi:10.1038/srep31464 · Cited by 89

Voxel-based Morphometry of the Visual-related Cortex in Primary Open Angle Glaucoma

Li, C., Cai, P., Shi, L., Lin, Y., Zhang, J., Liu, S., Xie, B., Shi, Y., Yang, H., Li, S., et al. (2012) · Current Eye Research · doi:10.3109/02713683.2012.683506 · Cited by 95

Glaucoma: A Degenerative Optic Neuropathy Related to Neuroinflammation?

Parsadaniantz, S. M., Goazigo, A. R.-L., Sapienza, A., Habas, C., & Baudouin, C. (2020) · Cells · doi:10.3390/cells9030535 · Cited by 88

Glaucoma neuroprotection: What is it? Why is it needed?

Weinreb, R. N. (2007) · Canadian Journal of Ophthalmology · doi:10.3129/i07-045 · Cited by 87

Glaucoma as Neurodegeneration in the Brain

Chan, J. W., Chan, N. C. Y., & Sadun, A. A. (2021) · Eye and Brain · doi:10.2147/eb.s293765 · Cited by 91

Neurodegeneration and Neuroprotection in Glaucoma.

Gauthier, A. C., & Liu, J. (2016) · Europe PMC (PubMed Central) · Cited by 85

The Outflow Pathway: A Tissue With Morphological and Functional Unity

Saccà, S. C., Gandolfi, S., Bagnis, A., Manni, G., Damonte, G., Traverso, C. E., & Izzotti, A. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25305 · Cited by 83

Anterior visual pathway assessment by magnetic resonance imaging in normal‐pressure glaucoma

Zhang, Y. Q., Li, J., Xu, L., Zhang, L., Wang, Z. C., Yang, H., Chen, C. X., Wu, X., & Jonas, J. B. (2012) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.2011.02346.x · Cited by 80

Functional MRI Signal Changes in Primary Visual Cortex Corresponding to the Central Normal Visual Field of Patients with Primary Open-Angle Glaucoma

Qing, G., Zhang, S., Wang, B., & Wang, N. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-4834 · Cited by 80

Variability of serum oxidative stress biomarkers relative to biochemical data and clinical parameters of glaucoma patients.

Engin, K. N., Yemisci, B., Yiğit, U., Ağaçhan, A., & Coşkun, C. (2010) · PubMed Central · Cited by 79

What Changes Can We Expect in the Brain of Glaucoma Patients?

Gupta, N., & Yücel, Y. H. (2007) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2007.08.006 · Cited by 78

Links among glaucoma, neurodegenerative, and vascular diseases of the central nervous system

Nucci, C., Martucci, A., Cesareo, M., Garaci, F. G., Morrone, L. A., Russo, R., Corasaniti, M. T., Bagetta, G., & Mancino, R. (2015) · Progress in brain research · doi:10.1016/bs.pbr.2015.04.010 · Cited by 78

Quantification of the Effect of Different Levels of IOP in the Astroglia of the Rat Retina Ipsilateral and Contralateral to Experimental Glaucoma

Ramirez, A. I., Salazar, J. J., de Hoz, R., Rojas, B., Gallego, B., Salinas‐Navarro, M., Alarcón-Martínez, L., Ortín-Martínez, A., Avilés‐Trigueros, M., Vidal‐Sanz, M., et al. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5248 · Cited by 77

Brain involvement in glaucoma: advanced neuroimaging for understanding and monitoring a new target for therapy

Nucci, C., Martucci, A., Cesareo, M., Mancino, R., Russo, R., Bagetta, G., Cerulli, L., & Garaci, F. G. (2012) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2012.08.004 · Cited by 75

Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys

Ito, Y., Shimazawa, M., Chen, Y., Tsuruma, K., Yamashima, T., Araie, M., & Hara, H. (2009) · Experimental Eye Research · doi:10.1016/j.exer.2009.03.013 · Cited by 74

Diffusion tensor magnetic resonance imaging reveals visual pathway damage that correlates with clinical severity in glaucoma

Chen, Z., Lin, F., Wang, J., Li, Z., Dai, H., Mu, K., Ge, J., & Zhang, H. (2012) · Clinical and Experimental Ophthalmology · doi:10.1111/j.1442-9071.2012.02832.x · Cited by 74

Assessment of Lateral Geniculate Nucleus Atrophy with 3T MR Imaging and Correlation with Clinical Stage of Glaucoma

Dai, H., Mu, K., Qi, J., Wang, C. Y., Zhu, W., Xia, L. M., Chen, Z. Q., Zhang, H., Ai, F., & Morelli, J. N. (2011) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2486 · Cited by 73

Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer’s disease

Salinaro, A. T. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00129 · Cited by 70

Altered Amplitude of Low-Frequency Fluctuation in Primary Open-Angle Glaucoma: A Resting-State fMRI Study

Li, T., Liu, Z., Li, J., Liu, Z., Tang, Z., Xie, X., Yang, D., Wang, N., Tian, J., & Xian, J. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-14974 · Cited by 71

Evidence for Widespread Structural Brain Changes in Glaucoma: A Preliminary Voxel-Based MRI Study

Williams, A. L., Lackey, J., Wizov, S. S., Chia, T. M. T., Gatla, S., Moster, M. L., Sergott, R. C., Spaeth, G. L., & Lai, S. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-11776 · Cited by 74

Embryonic stem cells and retinal repair

Vugler, A., Lawrence, J. M., Walsh, J., Carr, A. F., Gias, C., Semo, M., Ahmado, A., da Cruz, L., Andrews, P. W., & Coffey, P. J. (2007) · Mechanisms of Development · doi:10.1016/j.mod.2007.08.002 · Cited by 72

Molecular complexity of primary open angle glaucoma: current concepts

Ray, K., & Mookherjee, S. (2009) · Journal of Genetics · doi:10.1007/s12041-009-0065-3 · Cited by 70

Reduced Cortical Thickness in Primary Open-Angle Glaucoma and Its Relationship to the Retinal Nerve Fiber Layer Thickness

Yu, L., Xie, B., Yin, X., Liang, M., Evans, A. C., Wang, J., & Dai, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073208 · Cited by 70

Effect of epigallocatechin-gallate on inner retinal function in ocular hypertension and glaucoma: A short-term study by pattern electroretinogram

Falsini, B., Marangoni, D., Salgarello, T., Stifano, G., Montrone, L., Landro, S. D., Guccione, L., Balestrazzi, E., & Colotto, A. (2009) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-009-1064-z · Cited by 70

Bilateral neuroinflammatory processes in visual pathways induced by unilateral ocular hypertension in the rat

Sapienza, A., Raveu, A.-L., Reboussin, É., Roubeix, C., Boucher, C., Dégardin, J., Godefroy, D., Rostène, W. H., Goazigo, A. R.-L., Baudouin, C., et al. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0509-7 · Cited by 70

Altered Spontaneous Brain Activity in Primary Open Angle Glaucoma: A Resting-State Functional Magnetic Resonance Imaging Study

Song, Y., Mu, K., Wang, J., Lin, F., Chen, Z., Yan, X., Hao, Y., Zhu, W., & Zhang, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089493 · Cited by 69

White Matter Consequences of Retinal Receptor and Ganglion Cell Damage

Ogawa, S., Takemura, H., Horiguchi, H., Terao, M., Haji, T., Pestilli, F., Yeatman, J. D., Tsuneoka, H., Wandell, B. A., & Masuda, Y. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-14737 · Cited by 67

Multi-Target Effects of ß-Caryophyllene and Carnosic Acid at the Crossroads of Mitochondrial Dysfunction and Neurodegeneration: From Oxidative Stress to Microglia-Mediated Neuroinflammation

Iorio, R., Celenza, G., & Petricca, S. (2022) · Antioxidants · doi:10.3390/antiox11061199 · Cited by 75

Optic Nerve Cupping and the Neuro-Ophthalmologist

Fraser, C. L., White, A. J. R., Plant, G. T., & Martin, K. R. (2013) · Journal of Neuro-Ophthalmology · doi:10.1097/won.0000000000000080 · Cited by 68

Translational neuroprotection research in glaucoma: a review of definitions and principles

Casson, R. J., Chidlow, G., Ebneter, A., Wood, J. P. M., Crowston, J. G., & Goldberg, I. (2011) · Clinical and Experimental Ophthalmology · doi:10.1111/j.1442-9071.2011.02563.x · Cited by 67

Citicoline and Retinal Ganglion Cells: Effects on Morphology and Function

Parisi, V., Oddone, F., Ziccardi, L., Roberti, G., Coppola, G., & Manni, G. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666170703111729 · Cited by 71

Multifactorial Pathogenic Processes of Retinal Ganglion Cell Degeneration in Glaucoma towards Multi-Target Strategies for Broader Treatment Effects

Tezel, G. (2021) · Cells · doi:10.3390/cells10061372 · Cited by 68

Proton magnetic resonance spectroscopy revealed choline reduction in the visual cortex in an experimental model of chronic glaucoma

Chan, K. C., So, K., & Wu, E. X. (2008) · Experimental Eye Research · doi:10.1016/j.exer.2008.10.002 · Cited by 66

Trans-synaptic degeneration in the visual pathway: Neural connectivity, pathophysiology, and clinical implications in neurodegenerative disorders

Sharma, S., Chitranshi, N., Wall, R. V., Basavarajappa, D. K., Gupta, V., Mirzaei, M., Graham, S. L., Klistorner, A. I., & You, Y. (2021) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2021.06.001 · Cited by 66

Selective reduction of fMRI responses to transient achromatic stimuli in the magnocellular layers of the LGN and the superficial layer of the SC of early glaucoma patients

Zhang, P., Wen, W., Sun, X., & He, S. (2015) · Human Brain Mapping · doi:10.1002/hbm.23049 · Cited by 63

Disturbed spontaneous brain activity pattern in patients with primary angle-closure glaucoma using amplitude of low-frequency fluctuation: a fMRI study

Dai, X., Huang, X., Zhong, Y.-L., Zhou, F., Hu, P.-H., Shao, Y., Pei, C.-G., Liu, X.-H., & Zeng, X. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s87596 · Cited by 62

Focus on molecular events in the anterior chamber leading to glaucoma

Saccà, S. C., & Izzotti, A. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1493-z · Cited by 62

Brain‐Derived Neurotrophic Factor as a Biomarker in Primary Open‐Angle Glaucoma

Ghaffariyeh, A., Honarpisheh, N., Heidari, M. H., Puyan, S., & Abasov, F. (2010) · Optometry and Vision Science · doi:10.1097/opx.0b013e3181fc329f · Cited by 61

Wallerian and trans-synaptic degeneration contribute to optic radiation damage in multiple sclerosis: a diffusion tensor MRI study

Rocca, M. A., Mesaroš, Š., Preziosa, P., Pagani, E., Stošić-Opinćal, T., Dujmović, I., Drulovic, J. S., & Filippi, M. (2013) · Multiple Sclerosis Journal · doi:10.1177/1352458513485146 · Cited by 60

Whole-brain voxel-based analysis of diffusion tensor MRI parameters in patients with primary open angle glaucoma and correlation with clinical glaucoma stage

Dai, H., Yin, D., Hu, C., Morelli, J. N., Hu, S., Yan, X., & Xu, D. (2012) · Neuroradiology · doi:10.1007/s00234-012-1122-9 · Cited by 61

Gray matter alterations in visual cortex of patients with loss of central vision due to hereditary retinal dystrophies

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