CoChat
Sign Up
Cited by 217Nutritional Studies and DietChronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseases

Alternate healthy eating index 2010 and risk of chronic obstructive pulmonary disease among US women and men: Prospective study

Open access
Varraso, R., Chiuve, S. E., Fung, T. T., Barr, R. G., Hu, F. B., Willett, W. C., Camargo, C. A.·2015·BMJ
DOI 10.1136/bmj.h286PMC PMC4707519
Open this paper in CoChat — free accountOpen PDF

Abstract

OBJECTIVE: To investigate the association between the Alternate Healthy Eating Index 2010 (AHEI-2010)--a measure of diet quality--and the risk of chronic obstructive pulmonary disease (COPD). DESIGN: Prospective cohort study. SETTING: Participants in the Nurses' Health Study and the Health Professionals Follow-up Study, United States. PARTICIPANTS: 73,228 female nurses from 1984 to 2000 and 47,026 men from 1986 to 1998, who completed biennial questionnaires. MAIN OUTCOME MEASURES: The primary outcome was the self report of newly diagnosed COPD. Multivariable Cox proportional hazards models were adjusted for age, physical activity, body mass index, total energy intake, smoking, second hand tobacco exposure (only in the Nurses' Health Study), race/ethnicity, physician visits, US region, spouse's highest educational attainment (only in the Nurses' Health Study), and menopausal status (only in the Nurses' Health Study). RESULTS: Over the study period, 723 cases of newly diagnosed COPD occurred in women and 167 in men. In the pooled analysis, a significant negative association was seen between the risk of newly diagnosed COPD and fifths of the AHEI-2010: hazard ratios were 0.81 (95% confidence interval 0.51 to 1.29) for the second fifth, 0.98 (0.80 to 1.18) for the third fifth, 0.74 (0.59 to 0.92) for the fourth fifth, and 0.67 (0.53 to 0.85) for participants who ate the healthiest diet according to the AHEI-2010 (that is, were in the highest fifth), compared with those who ate the less healthy diet (participants in the lowest fifth). Similar findings were observed among ex-smokers and current smokers. CONCLUSIONS: A higher AHEI-2010 diet score (reflecting high intakes of whole grains, polyunsaturated fatty acids, nuts, and long chain omega-3 fats and low intakes of red/processed meats, refined grains, and sugar sweetened drinks) was associated with a lower risk of COPD in both women and men. These findings support the importance of a healthy diet in multi-interventional programs to prevent COPD.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1136/bmj.h286

Cites

35 of 35 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Varraso et al. reported the importance of a healthy diet in multi-interventional programs to prevent COPD.

    “Varraso et al., recently reported the importance of a healthy diet in multi-interventional programs to prevent COPD [108].”

    From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [108]

  • High intake of whole grains, polyunsaturated fatty acids, nuts, and long chain omega-3 fats, and low intake of red/processed meats, refined grains, and sugar-sweetened drinks, were associated with a lower risk of COPD in both women and men.

    “They showed that high intake of whole grains, polyunsaturated fatty acids, nuts, and long chain omega-3 fats, and low intake of red/processed meats, refined grains and sugar-sweetened drinks, were associated with a lower risk of COPD in both women and men.”

    From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [108]

  • A number of epidemiological studies have shown beneficial effects of n-3 fatty acids, vitamins, fruits, and vegetables on lung functions and the risk of COPD.

    “On the other hand, a number of epidemiological studies have shown the beneficial effects of n-3 fatty acids, vitamins, fruits and vegetables on lung functions and the risk of COPD [108,116,117,118,119,120,121,122].”

    From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [108]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Varraso, R., Chiuve, S. E., Fung, T. T., Barr, R. G., Hu, F. B., Willett, W. C., & Camargo, C. A.
Affiliations
  • Inserm (FR)
  • Brigham and Women's Hospital (US)
  • Harvard University (US)
  • Columbia University Irving Medical Center (US)
Corresponding author
Varraso, R.
ORCID
Venue
BMJ
Publisher
BMJ
Published
2015-02-03
Volume
350
Issue
feb03 7
Pages
h286-h286
ISSN
1756-1833 (ISSN-L)
DOI
10.1136/bmj.h286
PMC
PMC4707519
OpenAlex
W2164541899
Cited by
217
References
35
Citations by year
2026: 10 · 2025: 16 · 2024: 21 · 2023: 34 · 2022: 22 · 2021: 23 · 2020: 18 · 2019: 23 · 2018: 17 · 2017: 10 · 2016: 15 · 2015: 7
FWCI
17.46
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • BMJ (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
Funders
  • National Institutes of Health (CA-167552, CA 87969)
  • National Heart, Lung, and Blood Institute (HL 63841, R01HL063841, R01HL075476)
  • National Cancer Institute (CA-167552, CA-87969, P01CA087969)
  • National Institute of Allergy and Infectious Diseases (AI-52338, R21AI052338)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
Keywords
Alternate Healthy Eating Index-2010, diet quality, chronic obstructive pulmonary disease, dietary habits, whole grains, omega-3 fatty acids, nuts, red and processed meat, sugar-sweetened beverages, refined grains, smoking, COPD risk, Nurses' Health Study, Health Professionals Follow-up Study, sex differences, disease prevention, polyunsaturated fatty acids
MeSH terms
Adult, Aged, Asthma, Diet, Feeding Behavior, Female, Humans, Male, Middle Aged, Prospective Studies, Surveys and Questionnaires, Risk Factors, United States, Incidence, Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review