The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: a systematic review and meta-analysis
Open accessAbstract
Objective: To evaluate the evidence on the efficacy of psychosocial interventions for improving pregnancy rates and reducing distress for couples in treatment with assisted reproductive technology (ART). Design: Systematic review and meta-analysis. Data sources: PsycINFO, PubMed, EMBASE, CINAHL, Web of Science and The Cochrane Library between 1978 and April 2014. Study selection: Studies were considered eligible if they evaluated the effect of any psychosocial intervention on clinical pregnancy and/or distress in infertile participants, used a quantitative approach and were published in English. Data extraction: Study characteristics and results were extracted and the methodological quality was assessed. Effect sizes (ES; Hedges g) were pooled using a random effects model. Heterogeneity was assessed using the Q statistic and I 2 , and publication bias was evaluated using Egger’s method. Possible moderators and mediators were explored with meta-analyses of variances (ANOVAs) and meta-regression. Results: We identified 39 eligible studies (total N=2746 men and women) assessing the effects of psychological treatment on pregnancy rates and/or adverse psychological outcomes, including depressive symptoms, anxiety, infertility stress and marital function. Statistically significant and robust overall effects of psychosocial intervention were found for both clinical pregnancy (risk ratio=2.01; CI 1.48 to 2.73; p<0.001) and combined psychological outcomes (Hedges g=0.59; CI 0.38 to 0.80; p=0.001). The pooled ES for psychological outcomes were generally larger for women (g: 0.51 to 0.73) than men (0.13 to 0.34), but the difference only reached statistical significance for depressive symptoms (p=0.004). Meta-regression indicated that larger reductions in anxiety were associated with greater improvement in pregnancy rates (Slope 0.19; p=0.004). No clear-cut differences were found between effects of cognitive–behavioural therapy (CBT; g=0.84), mind–body interventions (0.61) and other intervention types (0.50). Conclusions: The present meta-analysis suggests that psychosocial interventions for couples in treatment for infertility, in particular CBT, could be efficacious, both in reducing psychological distress and in improving clinical pregnancy rates.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Furthermore, the overall effect size associated with randomised controlled trials of psychological interventions on combined psychological outcomes was non-significant and efficacy was not found to differ according to intervention type.”
From Infertility-related distress and clinical targets for psychotherapy: A qualitative study (2021) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Although mindfulness approaches have proven to be of limited efficacy for infertility-related distress, one mindfulness-based approach that has yet to be applied to infertility is loving-kindness meditation (LKM),41 which seems to map on well to both shame/self-blame and severed relationships with others.”
From Infertility-related distress and clinical targets for psychotherapy: A qualitative study (2021) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Though CBT has been applied to infertility in a number of studies, with limited results, there are a number of CBT-based techniques that have yet to be used but that may address some of the specific infertility-related psychological challenges raised in this study.”
From Infertility-related distress and clinical targets for psychotherapy: A qualitative study (2021) · cites this paper as [15]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“While cognitive restructuring, progressive muscle relaxation, and mindfulness meditation are the most-used and tested approaches to date for the treatment of infertility-related distress, their efficacy in this population is limited.15”
From Infertility-related distress and clinical targets for psychotherapy: A qualitative study (2021) · cites this paper as [15]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Though they were found to result in small reductions in anxiety, they were not found to improve depressive symptoms, infertility distress or marital functioning when adjusting for publication bias.”
From Infertility-related distress and clinical targets for psychotherapy: A qualitative study (2021) · cites this paper as [15]
In the citing paper
“Bai et al. [45] used the effect size d = 0.59 (medium effect [41]) for the calculation of the power analysis, which was determined in the meta-analysis by Frederiksen et al. [19].”
In the citing paper
“Furthermore, Frederiksen et al. [19] made some miscalculations in their meta-analysis [62].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
The Measurement of Observer Agreement for Categorical Data
Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · cited 1×
“Adjusted for publication bias (34)¶ – – – – – 0.”
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · cited 2×
“Catoire et al(77) France I: 50 (50) UCT Hypnosis MBI Individual 4 1 A: STAI − 4 (7) Galhardo et al(97) Portugal I: 55 (55)”
BackgroundPreferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
Wang, G., Ma, R., Qiao, G., Wada, K., Aizawa, Y., & Satoh, T. (2015) · Integrative Medicine International · doi:10.1159/000368408 · Cited by 18,762
Flagged first, then by citations
Research works printed but not linked: 6
- 10.1093/humrep/ · DOI
- 10.1037//0033-2909.86.3.638 · DOI · Paper page
- Gutierrez, 2008, Group psychological intervention in assisted human reproduction, Rev Iberoam Fertil Reprod Hum, 25, 47
- Bjornsen K . Opening the door to fertility. retreat to fertile ground: sometimes the secret to getting pregnant lies in just getting away from it all. Altern Med 2006 (88):80–1. http://search.ebscohost.com/login.aspx?direct=true&db=c8h&AN=2009216983&site=ehost-live
- 10.1037/0278-6133.19.6.568 · DOI
- Galhardo, 2013, Developing mindfulness and acceptance skills in infertility: the mindfulness based program for infertility, Aten Primaria, 45, 143
Cited by
Sorted by citations
Items 301–379 of 379
Sexual Health and Sexual Behavior
Bartos, S. E. (2020) · Oxford Research Encyclopedia of Psychology · doi:10.1093/acrefore/9780190236557.013.704
Assisted Reproductive Technologies
Boivin, J. (2019)
Patient Retention, Nursing Retention: The Importance of Empathic Communication and Nursing Support
Domar, A. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108859486.012
Ширяєва, Л., & Капустіна, Ю. (2019) · Науковий часопис НПУ імені М П Драгоманова Серія 12 Психологічні науки · doi:10.31392/npu-nc.series12.2019.8(53).12
Transition Times. Supporting the Child and Adolescent’s Transitions in Pediatric Condition
Ped, S. I. P. (2020) · Pediatric Reports · doi:10.4081/pr.2020.8758
Р.С., Ш., & Гуткевич, Е. В. (2020) · Сибирский вестник психиатрии и наркологии · doi:10.26617/1810-3111-2020-2(107)-51-59
Family Alliance Trajectories from Infertility to Parenthood
Darwiche, J., Antonietti, J., & Corboz‐Warnery, A. (2021) · Springer eBooks · doi:10.1007/978-3-030-51988-9_7
Depression for Surviving Ancestral HardshipsPreprint
Sheill, P. (2019) · doi:10.31234/osf.io/m9pq2
Rodino, I. S. (2019) · UWA Profiles and Research Repository (UWA) · doi:10.26182/5cae993ccc8f1
The effect of psychosocial interventions on infertility: Inconsistency of research data
Koumparou, M., Bakas, P., Chrousos, G. P., & Economou, M. P. (2021) · Psychiatriki · doi:10.22365/jpsych.2021.030
“Thus, it is considered necessary the design of clinical studies for the evaluation of the different types of interventions.21 Another covariate that may have significantly increased heterogeneity is the different cultural background of the participants, since the studies originated from countries with cultural differe…”
BackgroundInvestigating the Effect of Stress Management Counseling on the Sexual Function of Infertile Women
Shayan, A., Masoumi, S. Z., Khodakarami, B., Ahmadnia, H., Dastgerdian, F., & Rabiei, S. (2021) · Current Women s Health Reviews · doi:10.2174/1573404817666210910120749
Zhang, S., Zhou, M., Tang, H., & Guan, H. (2021) · Research Square · doi:10.21203/rs.3.rs-1006657/v1
Clinical Evaluation of Patients with Suspected Reproductive Endocrine Disorders
Roberts, R. E., Franks, S., & Jayasena, C. N. (2022) · doi:10.1093/med/9780198870197.003.0153
Härtl, K., Kästner, R., & Kowalcek, I. (2021) · Elsevier eBooks · doi:10.1016/b978-3-437-23917-5.00010-0
Becker, M. A., Silver, N. E., Chandy, A., & Maheshwari, S. (2019) · Springer eBooks · doi:10.1007/978-3-030-04245-5_7
Infertility and Assisted Reproduction: Psychosocial Aspects
Geller, P. A., Nelson, A. J., & Hartman, A. R. (2019) · Springer eBooks · doi:10.1007/978-1-4614-6439-6_1312-2
Härtl, K., Kästner, R., & Kowalcek, I. (2017) · Elsevier eBooks · doi:10.1016/b978-3-437-23916-8.00010-x
Romanenko, T. G., & Yesyp, N. V. (2022) · UKRAINIAN JOURNAL HEALTH OF WOMAN · doi:10.15574/hw.2022.158.34
Effectiveness of a program for overcoming infertility in infertile women: An exploratory studyPreprint
Kim, K.-M., Kim, J.-H., Park, C.-S., & Rhee, H.-S. (2022) · Research Square · doi:10.21203/rs.3.rs-1651886/v1
Akın, B., & Kocak, M. Y. (2022) · Turkiye Klinikleri Journal of Health Sciences · doi:10.5336/healthsci.2021-85176
Gameiro, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91497-0.00020-5
Apoyo psicológico a las mujeres en tratamientos de reproducción asistida
Uribe-Holguín, A. (2022) · NACIENDO Revista Española de Psicología y Psicopatología Perinatal e Infantil · doi:10.52961/02.epmt9560
Alpha casozepine and L-theanine in ameliorating stress levels in infertile couples: a review
Ahire, P., Stalin, C., & Saha, S. (2023) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20230844
Psychological Impact of the COVID-19 Pandemic on Childless Couples
Vasudevan, S. R., & Mohanraj, B. (2023) · Advances in psychology, mental health, and behavioral studies (APMHBS) book series · doi:10.4018/978-1-6684-7221-7.ch007
Li, W., Honggui, W., Hong, P., & Hong, L. (2023) · Revista Latino-Americana de Enfermagem · doi:10.1590/1518-8345.6388.3928
Application Status of Psychotherapy in Gynecology Field
牛, 梦. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.1361243
Evaluating the Perception for Psychological and Social Impact ofInfertility among Libyans
Ajaj, K., & Amer, K. (2023) · Journal of Gynecology Research Reviews & Reports · doi:10.47363/jgrrr/2023(5)183
“Thence, emerging the psychological interventions among infertile couples are positively correlated with fewer psychological distress, higher rates of pregnancy and improving marital satisfaction [7-9].”
BackgroundEffect of psychosocial stress during pregnancy against prostaglandin hormone levels in maternity
Sudirman, J., Kusniyanto, R. E., Saleng, H., Triananinsi, N., Syarif, S., & Iskandar, A. M. (2023) · International Journal of Public Health Science (IJPHS) · doi:10.11591/ijphs.v12i4.22968
Dehghan, M., Heidari, H., Khodabakhshi‐Koolaee, A., & Najdi, N. (2023) · Preventive Care In Nursing and Midwifery Journal · doi:10.61186/pcnm.13.3.1
Messinis, I. E., Messini, C. I., Anifandis, G., & Daponte, A. I. (2024) · Cambridge University Press eBooks · doi:10.1017/9781108961097.041 · Cited by 1
An Evolutionary Approach to Emotion Regulation
Kisley, M. A. (2024) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197544754.013.55
Ego, T. T., Altraide, B. O., & Ihudiebube-Splendor, C. N. (2024) · Journal of Health Applied Sciences and Management · doi:10.4314/johasam.v7i2.16
“It is recognition that fertility challenges can exact a heavy emotional toll, leading individuals or couples to navigate a complex terrain marked by stress, anxiety, and even depression (Frederiksen et al., 2015).”
BackgroundDepression and Anxiety in Women Pursuing Fertility Treatment in Spain
Martínez‐Borba, V., Pejó, L. A., Crespo-Delgado, E., Fadrique‐Jiménez, A., & Osma, J. (2024) · Springer eBooks · doi:10.1007/978-3-031-57824-3_4
Borges, M. L. (2024) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.22.2024.tde-25062024-104425 · Cited by 11
The Role of the Mental Health Professional in the ART Clinic Setting
Domar, A. D., & Rooney, K. L. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-21477-6.00294-7
PEKASIL, A. N., & Küçükkaraca, N. (2024) · OPUS Toplum Araştırmaları Dergisi · doi:10.26466/opusjsr.1550472
Serri, O., Meunier, A., Bouet, P., Hachem, H. E., Liu, B., & May‐Panloup, P. (2024) · Journal of Pharmacy and Pharmacology Research · doi:10.26502/fjppr.0100
Dehkordi, M. A., Farajkhoda, T., Khanabadi, M., & Shamsi, F. (2025) · International Journal of Reproductive BioMedicine (IJRM) · doi:10.18502/ijrm.v22i12.18062
Anxiety disorders in patients with infertility
Sulima, A. N., Владимирович, С. В., & Bakharovskaya, A. S. (2025) · Сибирский научный медицинский журнал · doi:10.18699/ssmj20250103
Effect of music on anxiety during intrauterine insemination: a randomized controlled trial
Baumgarten, S. C., Chen, V., Ogle, A. J., Fought, A. J., Li, Y., & Ainsworth, A. J. (2025) · F&S Reports · doi:10.1016/j.xfre.2025.05.008
Female Infertility Diagnosis and Adult-Onset Psychiatric Conditions: A Matched Cohort StudyPreprint
Messaoud, K. B., Zaks, N., Licciardi, F. L., Ramlau‐Hansen, C. H., Kahn, L. G., & Janecka, M. (2025) · medRxiv · doi:10.1101/2025.06.16.25329704
Najdgholami, Z., Amini, L., Montazeri, A., & Mohammadnoori, M. (2025) · Journal of Family & Reproductive Health · doi:10.18502/jfrh.v19i2.19301
“Some studies have shown that using complementary treatment methods that are low-risk, inexpensive and easy can help reduce stress and increase the chance of pregnancy in women (16), as well as reduce distress and increase the probability of pregnancy (17).”
Endometriose associada à infertilidade: uma revisão sistemática
Pereira, I. A. C., Ferreira, L. B., Costa, L. R., Polakiewicz, R. R., Vieira, J., Gardingo, L. F. D. F., & Costa, D. N. D. F. (2025) · STUDIES IN HEALTH SCIENCES · doi:10.54022/shsv6n3-021
Wu, Y., Hu, J., Zhu, J., Xiao, Z., Hu, H., & Qiu, S. (2025) · Research Square · doi:10.21203/rs.3.rs-6886103/v1
Xu, L., Guo, T., Chen, F., Ya, M., & Yan, Y. (2025) · Reproductive Health · doi:10.1186/s12978-025-02113-y
“This zygote subsequently develops into an embryo, which is then implanted into the female uterus; it is colloquially referred to as “test - tube baby” [3, 4].”
Global Ethics in IVF: Harmonizing Regulation, Ensuring Access, and Governing Innovation
Shoham, Z., Weissman, A., & Yaron, Y. (2025) · Journal of IVF-Worldwide · doi:10.46989/001c.142396
Impact de la prise en charge en assistance médicale à la procréation sur la sexualité des couples
Garcia, S., Clarotti, M.-A., Benhaïm, A., Morello, R., Denoual‐Ziad, C., & Dreyfus, M. (2025) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2025.09.088
Clinicians’ Perspective on Counseling Clients With Reproductive Trauma: A Phenomenological Study
Kent, V., & Overfelt, C. (2025) · Journal of Mental Health Counseling · doi:10.17744/mehc.47.4.02
The Support of Couples Struggling With Infertility in the Anna-Joachim Program
Hollósi, C., & Nagy, B. M. (2025) · The Family Journal · doi:10.1177/10664807251384267
“…is associated with temporarily elevated levels of symptoms of anxiety, depression and distress, most commonly manifested in experiencing forms of loss, grief, anger, sadness, reduced self-worth, shame and self-blame in both men and women affected (Coyle & Rue, 2015; Frederiksen et al., 2015).”
Shafierizi, S., Basirat, Z., Nasiri-Amiri, F., Kheirkhah, F., Geraili, Z., Pasha, H., & Mahbobeh, F. (2024) · Figshare · doi:10.6084/m9.figshare.26666185
Iranifard, E., Yas, A., Mansouri Ghezelhesari, E., Taghipour, A., Mahmoudinia, M., & Latifnejadroudsari, R. (2024) · Figshare · doi:10.6084/m9.figshare.26667310
Kiani, Z., Fakari, F. R., Hakimzadeh, A., Hajian, S., Fakari, F. R., & Nasiri, M. (2024) · Figshare · doi:10.6084/m9.figshare.26625841
Iranifard, E., Yas, A., Mansouri Ghezelhesari, E., Taghipour, A., Mahmoudinia, M., & Latifnejadroudsari, R. (2024) · Figshare · doi:10.6084/m9.figshare.26667313
Kiani, Z., Fakari, F. R., Hakimzadeh, A., Hajian, S., Fakari, F. R., & Nasiri, M. (2024) · Figshare · doi:10.6084/m9.figshare.26625838
Kiani, Z., Simbar, M., Hajian, S., Zayeri, F., Shahidi, M., Naz, M. S. G., & Ghasemi, V. (2020) · Figshare · doi:10.6084/m9.figshare.12134772
Kiani, Z., Simbar, M., Hajian, S., Zayeri, F., Shahidi, M., Naz, M. S. G., & Ghasemi, V. (2020) · Figshare · doi:10.6084/m9.figshare.12134778
Iranifard, E., Yas, A., Mansouri Ghezelhesari, E., Taghipour, A., Mahmoudinia, M., & Latifnejadroudsari, R. (2024) · Figshare · doi:10.6084/m9.figshare.26667316
Guo, Y., Fang, Z., Yu, L., Sun, X., Li, F., & Jin, L. (2023) · Figshare · doi:10.6084/m9.figshare.22608991
Iranifard, E., Yas, A., Mansouri Ghezelhesari, E., Taghipour, A., Mahmoudinia, M., & Latifnejadroudsari, R. (2024) · Figshare · doi:10.6084/m9.figshare.26667307
Sousa-Leite, M., Costa, R. A., Figueiredo, B., & Gameiro, S. (2026) · Pilot and Feasibility Studies · doi:10.1186/s40814-026-01778-x
“Even though some patients rejected the group format, this will be maintained because it is cost-effective and associated with higher efficacy (than individual/couple format) in fertility care [23].”
Pavlov, C., Merrill, E., & Limbers, C. A. (2026) · Journal of Reproductive and Infant Psychology · doi:10.1080/02646838.2026.2630338
Marshall, E. M., Pilkington, P. D., & Karantzas, G. C. (2026) · Journal of Reproductive and Infant Psychology · doi:10.1080/02646838.2026.2639384
Judit Szigeti, F., Soltész, K., Kazinczi, C., Szabó, G., Kovács, B. P., Sipos, M., Ujma, P. P., & Purebl, G. (2026) · Mentálhigiéné és Pszichoszomatika · doi:10.1556/0406.2025.00091
Psychological Aspects of Infertility, Assisted Conception and Perinatal Loss
Healy, S., Vaillancourt, K., & Rosan, C. (2026) · Cambridge University Press eBooks · doi:10.1017/9781911623496.011
Psychological Aspects of Infertility Among Men
Harrison, C., & Gamiero, S. (2026) · Endocrinology · doi:10.1007/978-3-319-29456-8_63-1
Zhao, S., Hu, R., & Zhang, L. (2026) · PeerJ · doi:10.7717/peerj.21238
“It is well-established that psychological distress, such as anxiety and depression, is associated with reduced pregnancy rates in women undergoing infertility treatment ( Turner et al., 2013 ; Frederiksen et al., 2015 ).”
Saran, A. B., Dhavale, G. G., & Saran, A. B. (2026) · Urology Horizons · doi:10.1016/j.urolhz.2026.100001
Prevalence of depression Among Infertile Women in Aden, Yemen: A Cross-Sectional StudyPreprint
Gubran, A. N. M., Mohammed, H. A. A., Awadh, L. G. A., Anwar, B., Ragheed, S., Ahmed, M. A., Ali, N. T., Darwiesh, S. M. M., Jamel, L. A., & Mohamed, A. I. (2026) · Research Square · doi:10.21203/rs.3.rs-9706961/v1
Park, S. A., & Kim, H. (2026) · Research Square · doi:10.21203/rs.3.rs-9279355/v1
Putra, M. A. D. T., Endratamma, M. A., Akbar, M. F., Hamid, A. A., & Mokhtar, M. H. (2026) · Medicina · doi:10.3390/medicina62071335
“First, psychological rehabilitation through CBT, mindfulness, and couple-centered interventions consistently reduces anxiety and depression, improves coping, enhances quality of life, strengthens relationship functioning, and supports treat-ment adherence and continuation [25,39–42 , 45].”
Naz, B., & Batool, S. S. (2026) · International Journal of Emerging Multidisciplinaries Social Science · doi:10.54938/ijemdss.2026.05.2.674
“Pregnancy rates improved more when there was a bigger reduction in anxiety (Frederiksen et al. (2015).”
Messina, A., Motarajji, S. E., Chimenti, C., Valloreo, F., Masturzo, B., & Leo, L. (2026) · Women · doi:10.3390/women6030052
“…priority involves the incorporation of patient-reported outcomes into fertility research and clinical practice. recognition of the psychological burden associated with infertility has highlighted the importance of evaluating treatment success beyond conventional reproductive metrics [31,36,37].”
Soultanopoulos, G. C., Idzenga, J. J., Kamperman, A. M., van Pampus, M. G., Ket, J. C. F., Henrichs, J., & Verhoeven, C. J. M. (2026) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/0167482x.2026.2714888 · Cited by 1
Arslan, B., & Topatan, S. (2026) · Archives of Women s Mental Health · doi:10.1007/s00737-026-01750-x
“…reviews and meta-analyses have further suggested that psychological and nursing-based interventions may contribute to reductions in anxiety, depression, and infertility-related distress during infertility treatment (Frederiksen et al. 2015; Purewal et al. 2018; Xu et al. 2025; Jackson et al. 2025).”
Qu, P., Zhang, Y., Li, Y., Wang, K., Hu, Q., Gao, L., Fu, X., Liang, S., Zhao, F., Ren, S., et al. (2026) · Annals of Medicine · doi:10.1080/07853890.2026.2731735
“Given that low-QoL in infertility patients is often associated with severe emotional distress, including stress, anxiety, and depression [31–33].”
A Systematic Review on the Impact of Mental Health on Reproductive Hormones and Fertility Outcomes
Ali, J., & Gami, N. (2026) · Cureus · doi:10.7759/cureus.118075
Lee, J., Park, S., & Nam, S. (2026) · Behavioral Sciences · doi:10.3390/bs16101956
“Infertility-related stress not only reduces the success of infertility treatment but also interferes with maintaining a healthy pregnancy after conception (Frederiksen et al., 2015).”
The Role of the Mental Health Professional in the ART Clinic
Domar, A. D., Martens, M., & Eller, M. (2026) · Springer eBooks · doi:10.1007/978-3-032-24372-0_18
Sobana, R. M., & Deva, B. J. (2026) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20263997
Metadata
- Authors
- Frederiksen, Y., Farver-Vestergaard, I., Skovgård, N. G., Ingerslev, H. J., & Zachariae, R.
- Affiliations
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Corresponding author
- Frederiksen, Yoon
- Venue
- BMJ Open
- Publisher
- BMJ
- Published
- 2015-01
- Volume
- 5
- Issue
- 1
- Pages
- e006592
- ISSN
- 2044-6055 (ISSN-L)
- PMC
- PMC4316425
- OpenAlex
- W2103859384
- Cited by
- 380
- References
- 112
- Citations by year
- 2026: 27 · 2025: 34 · 2024: 46 · 2023: 43 · 2022: 35 · 2021: 50 · 2020: 35 · 2019: 37 · 2018: 29 · 2017: 20 · 2016: 18 · 2015: 6
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ Open (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Aarhus Universitet
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
- Keywords
- psychosocial interventions, infertility, assisted reproduction, clinical pregnancy rate, psychological distress, depressive symptoms, anxiety, infertility stress, couples, cognitive behavioral therapy, mind-body interventions
- MeSH terms
- Mental Disorders, Female, Humans, Infertility, Male, Pregnancy, Pregnancy Outcome, Psychotherapy, Treatment Outcome, Pregnancy Rate, Reproductive Techniques, Assisted
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
