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Cited by 117Celiac Disease Research and ManagementAdolescent and Pediatric HealthcareGastrointestinal motility and disorders

Transition from childhood to adulthood in coeliac disease: the Prague consensus report

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Ludvigsson, Jonas F, Agreus, Lars, Ciacci, Carolina, Crowe, Sheila E, Geller, Marilyn G, Green, Peter H R, Hill, Ivor, Hungin, A Pali +11 more·2016·Gut
DOI 10.1136/gutjnl-2016-311574PMC PMC4975833
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Abstract

The process of transition from childhood to adulthood is characterised by physical, mental and psychosocial development. Data on the transition and transfer of care in adolescents/young adults with coeliac disease (CD) are scarce. In this paper, 17 physicians from 10 countries (Sweden, Italy, the USA, Germany, Norway, the Netherlands, Australia, Britain, Israel and Denmark) and two representatives from patient organisations (Association of European Coeliac Societies and the US Celiac Disease Foundation) examined the literature on transition from childhood to adulthood in CD. Medline (Ovid) and EMBASE were searched between 1900 and September 2015. Evidence in retrieved reports was evaluated using the Grading of Recommendation Assessment, Development and Evaluation method. The current consensus report aims to help healthcare personnel manage CD in the adolescent and young adult and provide optimal care and transition into adult healthcare for patients with this disease. In adolescence, patients with CD should gradually assume exclusive responsibility for their care, although parental support is still important. Dietary adherence and consequences of non-adherence should be discussed during transition. In most adolescents and young adults, routine small intestinal biopsy is not needed to reconfirm a childhood diagnosis of CD based on European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) or North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) criteria, but a biopsy may be considered where paediatric diagnostic criteria have not been fulfilled, such as, in a patient without biopsy at diagnosis, additional serology (endomysium antibody) has not been performed to confirm 10-fold positivity of tissue transglutaminase antibodies or when a no biopsy strategy has been adopted in an asymptomatic child.

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Cited by

Sorted by citations

Authors
Ludvigsson, J. F., Agreus, L., Ciacci, C., Crowe, S. E., Geller, M. G., Green, P. H. R., Hill, I., Hungin, A. P., Koletzko, S., Koltai, T., Lundin, K. E. A., Mearin, M. L., Murray, J. A., Reilly, N., Walker, M. M., Sanders, D. S., Shamir, R., Troncone, R., & Husby, S.
Affiliations
  • University of Nottingham (GB)
  • Division of Family Medicine, Karolinska Institutet, Sweden
  • University of Salerno (IT)
  • University of California San Diego (US)
  • Celiac Disease Foundation, Los Angeles, California, USA
  • Columbia University Irving Medical Center (US)
  • Nationwide Children's Hospital (US)
  • Durham University (GB)
  • Ludwig-Maximilians-Universität München (DE)
  • Hungary (for the Association of European Coeliac Societies, AOECS), Budapest, Hungary
  • Oslo University Hospital (NO)
  • Leiden University Medical Center (NL)
  • Mayo Clinic (US)
  • University of Newcastle Australia (AU)
  • Royal Hallamshire Hospital (GB)
  • Tel Aviv University (IL)
  • University of Naples Federico II (IT)
  • Odense University Hospital (DK)
Corresponding author
Ludvigsson, Jonas F
ORCID
Venue
Gut
Publisher
BMJ
Published
2016-04-18
Volume
65
Issue
8
Pages
1242-1251
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
DOI
10.1136/gutjnl-2016-311574
PMC
PMC4975833
OpenAlex
W2336030595
Cited by
117
References
8
Citations by year
2026: 10 · 2025: 12 · 2024: 10 · 2023: 11 · 2022: 12 · 2021: 18 · 2020: 14 · 2019: 8 · 2018: 9 · 2017: 13
FWCI
10.95
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Gut (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
  • University of Southern Denmark Research Portal (University of Southern Denmark) (acceptedVersion, cc-by)
  • Durham Research Online (Durham University) (acceptedVersion, other-oa)
  • Durham Research Online (Durham University) (submittedVersion, cc-by-nc)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Leiden Repository (Leiden University) (submittedVersion)
  • Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion)
  • Figshare (submittedVersion, cc-by-nc)
  • HighWire Press Open Archive (submittedVersion)
  • NOVA (University of Newcastle Australia) (submittedVersion, cc-by-nc)
  • Newcastle University ePrints (Newcastle Univesity) (cc-by-nc)
Funders
  • Regeneron Pharmaceuticals
  • Coeliac UK
  • Odense Universitetshospital
  • Vetenskapsrådet (522-2A09-195)
  • Svenska Läkaresällskapet (522-2A09-195)
Topics
  • Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
  • Health Sciences › Health Professions › Speech and Hearing › Adolescent and Pediatric Healthcare
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Keywords
celiac disease, transition from childhood to adulthood, adolescents, young adults, care transitions, dietary adherence, small bowel biopsy, diagnostic criteria, serology, anti-endomysial antibodies, anti-tissue transglutaminase antibodies, parental support, psychosocial development
MeSH terms
Adolescent, Adult, Biopsy, Celiac Disease, Europe, Humans, International Cooperation, Serologic Tests, United States, Consensus, Transition to Adult Care, Symptom Assessment

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