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Cited by 2,346Inflammatory Bowel DiseaseOcular Diseases and Behçet’s SyndromeAnorectal Disease Treatments and Outcomes

The DOI matches its Crossref record; 1,293 of the 1,293 references it cites were found in a registry or an index.

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

Open access
Lamb, Christopher Andrew, Kennedy, Nicholas A, Raine, Tim, Hendy, Philip Anthony, Smith, Philip J, Limdi, Jimmy K, Hayee, Bu’Hussain, Lomer, Miranda C E, Parkes, Gareth C, Selinger, Christian, Barrett, Kevin J, Davies, R Justin, Bennett, Cathy, Gittens, Stuart, Dunlop, Malcolm G, Faiz, Omar, Fraser, Aileen, Garrick, Vikki, Johnston, Paul D, Parkes, Miles, Sanderson, Jeremy, Terry, Helen, IBD guidelines eDelphi consensus group, Gaya, Daniel R, Iqbal, Tariq H, Taylor, Stuart A, Smith, Melissa, Brookes, Matthew, Hansen, Richard, Hawthorne, A Barney·2019·Gut
DOI 10.1136/gutjnl-2019-318484PMC PMC6872448
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Abstract

Ulcerative colitis and Crohn’s disease are the principal forms of inflammatory bowel disease. Both represent chronic inflammation of the gastrointestinal tract, which displays heterogeneity in inflammatory and symptomatic burden between patients and within individuals over time. Optimal management relies on understanding and tailoring evidence-based interventions by clinicians in partnership with patients. This guideline for management of inflammatory bowel disease in adults over 16 years of age was developed by Stakeholders representing UK physicians (British Society of Gastroenterology), surgeons (Association of Coloproctology of Great Britain and Ireland), specialist nurses (Royal College of Nursing), paediatricians (British Society of Paediatric Gastroenterology, Hepatology and Nutrition), dietitians (British Dietetic Association), radiologists (British Society of Gastrointestinal and Abdominal Radiology), general practitioners (Primary Care Society for Gastroenterology) and patients (Crohn’s and Colitis UK). A systematic review of 88 247 publications and a Delphi consensus process involving 81 multidisciplinary clinicians and patients was undertaken to develop 168 evidence- and expert opinion-based recommendations for pharmacological, non-pharmacological and surgical interventions, as well as optimal service delivery in the management of both ulcerative colitis and Crohn’s disease. Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care. Twenty research priorities to inform future clinical management are presented, alongside objective measurement of priority importance, determined by 2379 electronic survey responses from individuals living with ulcerative colitis and Crohn’s disease, including patients, their families and friends.

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Registry

Crossref · 10.1136/gutjnl-2019-318484

Cites

1293 of 1293 references verified0 citation errors · 0 not checkable

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Figures

Figure 1 Management of proctitis.
Figure 1 Management of proctitis.CC BY-NC · PubMed Central
Figure 2 Management of acute severe ulcerative colitis.
Figure 2 Management of acute severe ulcerative colitis.CC BY-NC · PubMed Central
Figure 3 Medical prophylaxis after ileocolonic resection for Crohn’s disease.
Figure 3 Medical prophylaxis after ileocolonic resection for Crohn’s disease.CC BY-NC · PubMed Central
Figure 4 Anti-TNF therapeutic drug monitoring.
Figure 4 Anti-TNF therapeutic drug monitoring.CC BY-NC · PubMed Central
Figure 5 Osteoporosis prevention and management in IBD.
Figure 5 Osteoporosis prevention and management in IBD.CC BY-NC · PubMed Central
Figure 6 Use of faecal calprotectin in primary care.
Figure 6 Use of faecal calprotectin in primary care.CC BY-NC · PubMed Central
Figure 7 The IBD multidisciplinary team (MDT). It is important that the MDT meets regularly to review cases and make recommendations. All members of the team should have input as appropriate, but those in the inner box should be present at all regular MDT meetings. Staff in the middle box can and should be encouraged to attend these meetings, but this may not always be possible and they should nevertheless be encouraged to contribute reports or opinions. Staff in the outer box are part of the wider MDT and may contribute to team function through clinical input outside of these team meetings, such as through combined clinics or working to shared protocols. Staff in the grey circle should attend as a valuable part of their training.
Figure 7 The IBD multidisciplinary team (MDT). It is important that the MDT meets regularly to review cases and make recommendations. All members of the team should have input as appropriate, but those in the inner box should be present at all regular MDT meetings. Staff in the middle box can and should be encouraged to attend these meetings, but this may not always be possible and they should nevertheless be encouraged to contribute reports or opinions. Staff in the outer box are part of the wider MDT and may contribute to team function through clinical input outside of these team meetings, such as through combined clinics or working to shared protocols. Staff in the grey circle should attend as a valuable part of their training.CC BY-NC · PubMed Central

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Citations

Cites

1 retracted

Research works printed but not linked: 8

  1. Sands, 2018, LB01 Safety and efficacy of ustekinumab induction therapy in patients with moderate to severe ulcerative colitis: results from the Phase 3 UNIFI study, United Eur Gastroenterol J, 6, 1586
  2. Panaccione, 2017, OP017 Treat to target for Crohn’s disease with adalimumab treatment is cost effective over 48 weeks: An economic assessment of the CALM trial, United Eur Gastroenterol J, 5, A8
  3. Friedman, 2018, Randomised clinical trial: efficacy, safety and dosage of adjunctive allopurinol in azathioprine/mercaptopurine nonresponders (AAA Study), Aliment Pharmacol Ther, 47, 1092, 10.1111/apt.14571 · DOI
  4. Schwesinger, 1979, Complications in colonoscopy, Surg Gynecol Obstet, 148, 270
  5. Kanis, 2017, Long-term health outcomes of 1000 children born to mothers with inflammatory bowel disease in the anti-TNF-α era, United Eur Gastroenterol J, 5, A149
  6. Gordon, 2014, Prevention of opportunistic infections in patients on biological agents for management of inflammatory bowel disease, United Eur Gastroenterol J, 2, A373
  7. Fuertes, 2015, An evaluation of a pharmacist-led telephone clinic with regard to monitoring, safety and quality of service on patients taking thiopurines for the treatment of inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH) at Barnsley Hospital NHS, United Eur Gastroenterol J, 3, A256
  8. Price, 2013, The UK’s first internet based remote management system for monitoring stable IBD patients in the community, IBD SSHAMP (supported self help and management programme), United Eur Gastroenterol J, 1, A52

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Metadata

Authors
Lamb, C. A., Kennedy, N. A., Raine, T., Hendy, P. A., Smith, P. J., Limdi, J. K., Hayee, B., Lomer, M. C. E., Parkes, G. C., Selinger, C., Barrett, K. J., Davies, R. J., Bennett, C., Gittens, S., Dunlop, M. G., Faiz, O., Fraser, A., Garrick, V., Johnston, P. D., Parkes, M., Sanderson, J., Terry, H., IBD guidelines eDelphi consensus group, Gaya, D. R., Iqbal, T. H., Taylor, S. A., Smith, M., Brookes, M., Hansen, R., & Hawthorne, A. B.
Affiliations
  • Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
  • University of Exeter (GB)
  • Cambridge University Hospitals NHS Foundation Trust (GB)
  • Chelsea and Westminster Hospital NHS Foundation Trust (GB)
  • Royal Liverpool and Broadgreen University Hospital NHS Trust (GB)
  • Pennine Acute Hospitals NHS Trust (GB)
  • King's College London (GB)
  • Queen Mary University of London (GB)
  • University of Leeds (GB)
  • Royal College of Surgeons in Ireland (IE)
  • Western General Hospital (GB)
  • St Mark's Hospital (GB)
  • University Hospitals Bristol NHS Foundation Trust (GB)
  • Royal Hospital for Children (GB)
  • Crohn's and Colitis UK (GB)
  • Glasgow Royal Infirmary (GB)
  • Queen Elizabeth Hospital Birmingham (GB)
  • University College London Hospitals NHS Foundation Trust (GB)
  • Brighton and Sussex Medical School (GB)
  • University of Wolverhampton (GB)
  • University Hospital of Wales (GB)
Corresponding author
Lamb, Christopher Andrew
ORCID
Venue
Gut
Publisher
BMJ
Published
2019-09-27
Volume
68
Issue
Suppl 3
Pages
s1-s106
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
DOI
10.1136/gutjnl-2019-318484
PMC
PMC6872448
OpenAlex
W2976362764
Cited by
2,346
References
1,293
Citations by year
2026: 184 · 2025: 351 · 2024: 417 · 2023: 432 · 2022: 387 · 2021: 354 · 2020: 203 · 2019: 13
FWCI
144.34
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Gut (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion, cc-by-sa)
  • Discovery Research Portal (University of Dundee) (submittedVersion, cc-by-nc)
  • UCL Discovery (University College London) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
  • Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
  • Royal Devon and Exeter Research Repository (Royal Devon and Exeter) (submittedVersion, other-oa)
  • Wolverhampton Intellectual Repository and E-Theses (University of Wolverhampton) (submittedVersion, cc-by-nc)
  • Newcastle University ePrints (Newcastle Univesity) (cc-by-nc)
Funders
  • British Dietetic Association
  • Cancer Research UK (18927, 12076)
  • National Institute for Health and Care Research (ACF-2014-14-002, CL-2014-01-005, 13/179/01, EME/13/179/01)
  • Crohn's and Colitis UK
  • Medical Research Council (MR/M00533X/1, MC_UU_00007/1)
Topics
  • Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
  • Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
  • Health Sciences › Medicine › Surgery › Anorectal Disease Treatments and Outcomes
Keywords
inflammatory bowel disease, ulcerative colitis, Crohn's disease, immunosuppressive therapy, nutrition interventions, surgical management, multidisciplinary team, primary-secondary care integration, patient priorities, Delphi consensus
MeSH terms
Conservative Treatment, Systematic Reviews as Topic, Adult, Gastroenterology, United Kingdom, Humans, Societies, Medical, Inflammatory Bowel Diseases, Practice Guidelines as Topic, Disease Management, Consensus

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