The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
The role of laboratory investigation in the diagnosis and management of patients with suspected herpes simplex encephalitis: a consensus report. The EU Concerted Action on Virus Meningitis and Encephalitis.
Open accessAbstract
As effective therapies for the treatment of herpes simplex encephalitis (HSE) have become available, the virology laboratory has acquired a role of primary importance in the early diagnosis and clinical management of this condition. Several studies have shown that the polymerase chain reaction (PCR) of CSF for the detection of herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) DNA provides a reliable method for determining an aetiological diagnosis of HSE. The use of PCR in combination with the detection of a specific intrathecal antibody response to HSV currently represents the most reliable strategy for the diagnosis and monitoring of the treatment of adult patients with HSE. The use of these techniques has also led to the identification of atypical presentations of HSV infections of the nervous system and permits the investigation of patients who develop a relapse of encephalitic illness after an initial episode of HSE. A strategy for the optimal use of the investigative laboratory in the diagnosis of HSE and subsequent management decisions is described.
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Cites
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ACYCLOVIR VERSUS VIDARABINE IN HERPES SIMPLEX ENCEPHALITIS
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Cited by
Gultekin, S. H. (2000) · Brain · doi:10.1093/brain/123.7.1481 · Cited by 1,123
Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs
Reiber, H., & Peter, J. B. (2001) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(00)00501-3 · Cited by 731
Molecular Methods for Diagnosis of Viral Encephalitis
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Studahl, M., Lindquist, L., Eriksson, B.-M., Günther, G., Bengner, M., Franzen-Röhl, E., Fohlman, J., Bergström, T., & Aurelius, E. (2013) · Drugs · doi:10.1007/s40265-013-0007-5 · Cited by 90
Herpes Simplex Virus Type 2 as a Cause of Severe Meningitis in Immunocompromised Adults
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Metadata
- Authors
- Cinque, P., Cleator, G. M., Weber, T., Monteyne, P., Sindic, C. J., & van Loon, A. M.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1996-10-01
- Volume
- 61
- Issue
- 4
- Pages
- 339-345
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2030440655
- Cited by
- 261
- References
- 66
- FWCI
- 10.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: The role of laboratory investigation in the diagnosis and management of patients with suspected herpes simplex encephalitis: a consensus report. The EU Concerted Action on Virus Meningitis and Encephalitis. https://app.cochat.ai/papers/10.1136/jnnp.61.4.339
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- Cinque, P., Cleator, G. M., Weber, T., Monteyne, P., Sindic, C. J., & van Loon, A. M. (1996). The role of laboratory investigation in the diagnosis and management of patients with suspected herpes simplex encephalitis: a consensus report. The EU Concerted Action on Virus Meningitis and Encephalitis. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.61.4.339
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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