Cited by 17Metabolism, Diabetes, and CancerCardiovascular and exercise physiologyMuscle Physiology and Disorders

Effects of an acute bout of resistance exercise on fiber-type specific GLUT4 and IGF-1R expression

Gallagher, Philip M., Touchberry, Chad D., Teson, Kelli, McCabe, Everlee, Tehel, Michelle, Wacker, Michael J.·2013·Applied Physiology Nutrition and Metabolism

Abstract

The effects of resistance exercise on fiber-type-specific expression of insulin-like growth factor I receptor (IGF-1R) and glucose transporter 4 (GLUT4) was determined in 6 healthy males. The expression of both genes increased in Type I fibers (p < 0.05), but only GLUT4 increased (p < 0.05) in Type II fibers. These data demonstrates that an acute bout of resistance exercise can up-regulate mechanisms of glucose uptake in slow and fast-twitch fibers, but the IGF signaling axis may not be as effective in fast-twitch fibers.

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Crossref · 10.1139/apnm-2012-0301

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52 of 52 references verified0 citation errors · 0 not checkable

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Authors
Gallagher, P. M., Touchberry, C. D., Teson, K., McCabe, E., Tehel, M., & Wacker, M. J.
Affiliations
  • University of Kansas (US)
  • University of Missouri–Kansas City (US)
Venue
Applied Physiology Nutrition and Metabolism
Published
2013-05
Volume
38
Issue
5
Pages
581-586
ISSN
  • 1715-5312 (ISSN-L)
  • 1715-5320
OpenAlex
W1974464485
Cited by
17
References
52
Citations by year
2025: 2 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 2 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 1
FWCI
0.60
Type
journal article
Language
en
Open access
closed
Locations
  • Applied Physiology Nutrition and Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Funders
American Heart Association
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Keywords
resistance training, GLUT4, IGF-1 receptor, skeletal muscle fiber types, type I muscle fibers, type II fibers, glucose uptake, IGF signaling, gene expression, acute exercise
MeSH terms
Dietary Fiber, Humans, Insulin-Like Growth Factor I, Signal Transduction, Exercise, Muscle Fibers, Fast-Twitch, Glucose Transporter Type 4

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