Cited by 469Machine Learning in HealthcareMedical Coding and Health InformationElectronic Health Records Systems

Multi-layer Representation Learning for Medical Concepts

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Choi, Edward, Bahadori, Mohammad Taha, Searles, Elizabeth, Coffey, Catherine, Thompson, Michael, Bost, James, Tejedor-Sojo, Javier, Sun, Jimeng·2016·Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining

Abstract

Proper representations of medical concepts such as diagnosis, medication, procedure codes and visits from Electronic Health Records (EHR) has broad applications in healthcare analytics. Patient EHR data consists of a sequence of visits over time, where each visit includes multiple medical concepts, e.g., diagnosis, procedure, and medication codes. This hierarchical structure provides two types of relational information, namely sequential order of visits and co-occurrence of the codes within a visit. In this work, we propose Med2Vec, which not only learns the representations for both medical codes and visits from large EHR datasets with over million visits, but also allows us to interpret the learned representations confirmed positively by clinical experts. In the experiments, Med2Vec shows significant improvement in prediction accuracy in clinical applications compared to baselines such as Skip-gram, GloVe, and stacked autoencoder, while providing clinically meaningful interpretation.

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  • The lack of an industry standard for health information exchange was the main reason behind the slow adoption of the EHR system in healthcare organizations even if their adoption was highly beneficial.

    “It was the main reason behind the slow adoption of the EHR system in healthcare organizations even if their adoption was highly beneficial for them [25].”

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Research works printed but not linked: 6

  1. Y. Bengio, R. Ducharme, P. Vincent, and C. Janvin. A neural probabilistic language model. JMLR, 2003.
  2. M. Ghassemi, T. Naumann, F. Doshi-Velez, N. Brim- mer, R. Joshi, A. Rumshisky, and P. Szolovits. Unfold- ing physiological state: Mortality modelling in intensive care units. In KDD, 2014.
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Authors
Choi, E., Bahadori, M. T., Searles, E., Coffey, C., Thompson, M., Bost, J., Tejedor-Sojo, J., & Sun, J.
Affiliations
  • Georgia Institute of Technology (US)
  • Children's Healthcare of Atlanta (US)
  • Children's Healthcare of Atlanta, Atlanta, GA, USA
Venue
Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining
Publisher
ACM
Published
2016-08-13
Pages
1495-1504
OpenAlex
W2284851926
Cited by
469
References
34
Citations by year
2026: 13 · 2025: 25 · 2024: 31 · 2023: 53 · 2022: 43 · 2021: 63 · 2020: 85 · 2019: 80 · 2018: 48 · 2017: 22 · 2016: 6
FWCI
28.02
Type
conference paper
Language
en
Open access
Locations
  • ACM SIGKDD Conference on Knowledge Discovery and Data Mining (KDD) (publishedVersion)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Funders
  • Samsung Scholarship
  • Centers for Disease Control and Prevention
  • National Science Foundation (1418511)
  • Google
  • Children's Healthcare of Atlanta
  • UCB
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
Keywords
electronic health records, clinical codes, diagnosis codes, medication codes, procedure codes, clinical interpretability, medical data analysis

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