The DOI matches its Crossref record; 140 of the 140 references it cites were found in a registry or an index.
The Cryptochromes: Blue Light Photoreceptors in Plants and Animals
Abstract
Cryptochromes are flavoprotein photoreceptors first identified in Arabidopsis thaliana, where they play key roles in growth and development. Subsequently identified in prokaryotes, archaea, and many eukaryotes, cryptochromes function in the animal circadian clock and are proposed as magnetoreceptors in migratory birds. Cryptochromes are closely structurally related to photolyases, evolutionarily ancient flavoproteins that catalyze light-dependent DNA repair. Here, we review the structural, photochemical, and molecular properties of cry-DASH, plant, and animal cryptochromes in relation to biological signaling mechanisms and uncover common features that may contribute to better understanding the function of cryptochromes in diverse systems including in man.
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In the citing paper
“In the coral Acropora millepora, three types of Crys were identified (24): Ami-Cry1 has closest homology to tr-Crys, Ami-Cry2 is positioned in the group of the 6-4 photolyases, while the third molecule, Ami-CryDash, is related to another ancient group of Crys that has been dubbed “cry-Drosophila, Arabidopsis, Synechocystis, Homo” (Cry-DASH) due to its broad evolutionary conservation (32).”
From An Overview of Monthly Rhythms and Clocks (2017) · cites this paper as [32]
In the citing paper
“Molecular phylogenetic analyses show that Crys form multiple, evolutionarily conserved subgroups (32–34).”
From An Overview of Monthly Rhythms and Clocks (2017) · cites this paper as [32]
In the citing paper
“Crys are flavoproteins involved in cellular signaling, which are anciently related to photolyases, UV-responsive DNA repair enzymes (32).”
From An Overview of Monthly Rhythms and Clocks (2017) · cites this paper as [32]
Citations
Cites
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Self-citationA Model for Photoreceptor-Based Magnetoreception in Birds
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The Radical-Pair Mechanism of Magnetoreception
Hore, P. J., & Mouritsen, H. (2016) · Annual Review of Biophysics · doi:10.1146/annurev-biophys-032116-094545 · Cited by 813
Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder
Patke, A., Murphy, P. J., Onat, O. E., Krieger, A. C., Özçelik, T., Campbell, S. S., & Young, M. W. (2017) · Cell · doi:10.1016/j.cell.2017.03.027 · Cited by 381
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SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket
Xing, W., Busino, L., Hinds, T. R., Marionni, S. T., Saifee, N. H., Bush, M. F., Pagano, M., & Zheng, N. (2013) · Nature · doi:10.1038/nature11964 · Cited by 234
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The cryptochrome/photolyase family in aquatic organisms
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Dynamics and mechanisms of DNA repair by photolyase
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Light-Harvesting Complexes of Diatoms: Fucoxanthin-Chlorophyll Proteins
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Metadata
- Authors
- Chaves, I., Pokorny, R., Byrdin, M., Hoang, N., Ritz, T., Brettel, K., Essen, L.-O., van der Horst, G. T. J., Batschauer, A., & Ahmad, M.
- Affiliations
- Erasmus MC (NL)
- Philipps University of Marburg (DE)
- Centre National de la Recherche Scientifique (FR)
- Université Pierre-et-Marie-Curie (FR)
- University of California, Irvine (US)
- Department of Genetics, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands;,
- Pennsylvania State University (US)
- ORCID
- Venue
- Annual Review of Plant Biology
- Publisher
- Annual Reviews
- Published
- 2011-06-02
- Volume
- 62
- Issue
- 1
- Pages
- 335-364
- ISSN
- 1543-5008 (ISSN-L)
- 1545-2123
- OpenAlex
- W2117719962
- Cited by
- 845
- References
- 140
- Citations by year
- 2026: 44 · 2025: 45 · 2024: 35 · 2023: 59 · 2022: 74 · 2021: 54 · 2020: 65 · 2019: 59 · 2018: 66 · 2017: 71 · 2016: 57 · 2015: 59 · 2014: 70 · 2013: 41 · 2012: 37
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Plant Biology (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- cryptochrome, blue-light photoreceptor, flavoprotein, photolyase, circadian clock, magnetoreception, bird migration, Arabidopsis thaliana, plant development, photochemistry, flavin cofactor, DNA repair
- MeSH terms
- Adenosine Triphosphate, Animals, Deoxyribodipyrimidine Photo-Lyase, DNA Repair, Homing Behavior, Insecta, Magnetics, Oxidation-Reduction, Phosphorylation, Plants, Mice, Light Signal Transduction, Cryptochromes
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