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Sex and Gender Differences in the Outcomes of Vaccination over the Life Course
Open accessAbstract
Both sex (i.e., biological differences) and gender (i.e., social or cultural influences) impact vaccine acceptance, responses, and outcomes. Clinical data illustrate that among children, young adults, and aged individuals, males and females differ in vaccine-induced immune responses, adverse events, and protection. Although males are more likely to receive vaccines, following vaccination, females typically develop higher antibody responses and report more adverse effects of vaccination than do males. Human, nonhuman animal, and in vitro studies reveal numerous immunological, genetic, hormonal, and environmental factors that differ between males and females and contribute to sex- and gender-specific vaccine responses and outcomes. Herein, we address the impact of sex and gender variables that should be considered in preclinical and clinical studies of vaccines.
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“In adults, women have shown to mount higher immune responses than men and are more likely to report adverse reactions36.”
From An Omicron-specific, self-amplifying mRNA booster vaccine for COVID-19: a phase 2/3 randomized trial (2024) · cites this paper as [36]
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Cites
Sex differences in immune responses
Klein, S. L., & Flanagan, K. L. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.90 · Cited by 6,370
Self-citationWegmann, T. G., Lin, H., Guilbert, L., & Mosmann, T. R. (1993) · Immunology Today · doi:10.1016/0167-5699(93)90235-d · Cited by 2,852
Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
Markle, J. G. M., Frank, D. N., Mortin-Toth, S., Robertson, C. E., Feazel, L. M., Rolle-Kampczyk, U., von Bergen, M., McCoy, K. D., Macpherson, A. J., & Danska, J. S. (2013) · Science · doi:10.1126/science.1233521 · Cited by 2,025
The Application of Ecological Theory Toward an Understanding of the Human Microbiome
Costello, E. K., Stagaman, K., Dethlefsen, L., Bohannan, B. J. M., & Relman, D. A. (2012) · Science · doi:10.1126/science.1224203 · Cited by 1,437
Tobi, E. W., Lumey, L. H., Talens, R. P., Kremer, D., Putter, H., Stein, A. D., Slagboom, P. E., & Heijmans, B. T. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp353 · Cited by 1,173
Symbiotic gut microbes modulate human metabolic phenotypes
Li, M., Wang, B., Zhang, M., Rantalainen, M., Wang, S., Zhou, H., Zhang, Y., Shen, J., Pang, X., Zhang, M., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712038105 · Cited by 1,144
Estrogen receptors regulate innate immune cells and signaling pathways
Kovats, S. (2015) · Cellular Immunology · doi:10.1016/j.cellimm.2015.01.018 · Cited by 1,021
Mueller, S., Saunier, K., Hanisch, C., Norin, E., Alm, L., Midtvedt, T., Cresci, A., Silvi, S., Orpianesi, C., Verdenelli, M. C., et al. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.2.1027-1033.2006 · Cited by 1,006
Gender Bias in Autoimmunity Is Influenced by Microbiota
Yurkovetskiy, L., Burrows, M. P., Khan, A. A., Graham, L., Volchkov, P., Becker, L., Antonopoulos, D. A., Umesaki, Y., & Chervonsky, A. V. (2013) · Immunity · doi:10.1016/j.immuni.2013.08.013 · Cited by 943
The Xs and Y of immune responses to viral vaccines
Klein, S. L., Jedlicka, A., & Pekosz, A. S. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70049-9 · Cited by 813
Self-citation
Research works printed but not linked: 6
- Altet MN, 1992, Med. Clin, 99, 612
- Bocsan IS, 2005, Rev. Med. Chir. Soc. Med. Nat. Iasi, 109, 124
- Jackowska T, 2008, Med. Wieku Rozwojowego, 12, 653
- Narayanan PR, 2006, Indian J. Med. Res, 123, 119
- Philipps J, 1996, Wien. Klin. Wochenschr., 108, 615
- Wilson EB, 2011, Curr. Top. Microbiol. Immunol., 350, 39
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Al-Amer, R. M., Maneze, D., Everett, B., Montayre, J., Villarosa, A. R., Dwekat, E., & Salamonson, Y. (2021) · Journal of Clinical Nursing · doi:10.1111/jocn.15951 · Cited by 278
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Potluri, T., Fink, A. L., Sylvia, K. E., Dhakal, S., Vermillion, M. S., Steeg, L. G. V., Deshpande, S., Narasimhan, H., & Klein, S. L. (2019) · npj Vaccines · doi:10.1038/s41541-019-0124-6 · Cited by 187
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Steinert, J., Sternberg, H., Prince, H., Fasolo, B., Galizzi, M. M., Büthe, T., & Veltri, G. (2022) · Science Advances · doi:10.1126/sciadv.abm9825 · Cited by 170
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Nomura, S., Eguchi, A., Yoneoka, D., Kawashima, T., Tanoue, Y., Murakami, M., Sakamoto, H., Maruyama‐Sakurai, K., Gilmour, S., Shi, S., et al. (2021) · The Lancet Regional Health - Western Pacific · doi:10.1016/j.lanwpc.2021.100223 · Cited by 139
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Liu, R., & Li, G. M. (2021) · SSM - Population Health · doi:10.1016/j.ssmph.2021.100896 · Cited by 136
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Adu, P., Popoola, T., Medvedev, O. N., Collings, S. C., Mbinta, J. F., Aspin, C., & Simpson, C. R. (2023) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2023.01.020 · Cited by 82
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Shi, Y., Ma, J., Li, S., Liu, C., Liu, Y., Chen, J., Liu, N., Liu, S., & Huang, H. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01929-7 · Cited by 91
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Fathi, A., Addo, M. M., & Dahlke, C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.601170 · Cited by 59
Mackey, E. E., Thelen, K. M., Bali, V., Fardisi, M., Trowbridge, M., Jordan, C. L., & Moeser, A. J. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1915075117 · Cited by 58
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Nachtigall, I., Bonsignore, M., Hohenstein, S., Bollmann, A., Günther, R., Kodde, C., Englisch, M., Ahmad‐Nejad, P., Schröder, A., Glenz, C., et al. (2022) · BMC Infectious Diseases · doi:10.1186/s12879-022-07284-8 · Cited by 58
Long-term Immunogenicity of Measles Vaccine: An Italian Retrospective Cohort Study
Bianchi, F. P., Stefanizzi, P., Nitto, S. D., Larocca, A. M. V., Germinario, C. A., & Tafuri, S. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz508 · Cited by 56
Position of nuclear medicine techniques in the diagnostic work-up of neuroendocrine tumors.
Bombardieri, E., Seregni, E. C., Villano, C., Chiti, A., & Bajetta, E. (2004) · PubMed · Cited by 56
Sex-Based Vaccine Response in the Context of COVID-19
McCartney, P. R. (2020) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1016/j.jogn.2020.08.001 · Cited by 56
The gut microbiome as a biomarker of differential susceptibility to SARS-CoV-2
Sarkar, A., Harty, S., Moeller, A. H., Klein, S. L., Erdman, S. E., Friston, K. J., & Carmody, R. N. (2021) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2021.09.009 · Cited by 56
Self-citationSpiegel, K., Rey, A. E., Cheylus, A., Ayling, K., Benedict, C., Lange, T., Prather, A. A., Taylor, D. J., Irwin, M. R., & Cauter, E. V. (2023) · Current Biology · doi:10.1016/j.cub.2023.02.017 · Cited by 57
Tadount, F., Doyon-Plourde, P., Rafferty, E., MacDonald, S. E., Sadarangani, M., & Quach, C. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.10.091 · Cited by 54
Galanis, P., Vraka, I. S., Katsiroumpa, A., Siskou, O. C., Konstantakopoulou, O., Katsoulas, T. A., Mariolis-Sapsakos, T. D., & Καϊτελίδου, Δ. (2022) · Vaccines · doi:10.3390/vaccines10071097 · Cited by 55
Sex Differences in Influenza: The Challenge Study Experience
Giurgea, L. T., Cervantes-Medina, A., Walters, K., Scherler, K., Han, A., Czajkowski, L. M., Baus, H. A., Hunsberger, S., Klein, S. L., Kash, J. C., et al. (2021) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiab422 · Cited by 52
Self-citationSafety and Reactogenicity of the ChAdOx1 (AZD1222) COVID-19 Vaccine in Saudi Arabia
Bahrani, S. A., Albarrak, A. M., Alghamdi, O. A., Alghamdi, M. A., Hakami, F. H., Abaadi, A. K. A., Alkhrashi, S. A., Alghamdi, M. Y., Almershad, M. M., Alanazi, M. M., et al. (2021) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2021.07.052 · Cited by 52
Salciccia, S., Giudice, F. D., Gentile, V., Mastroianni, C. M., Pasculli, P., Lascio, G. D., Ciardi, M. R., Sperduti, I., Maggi, M., BERARDINIS, E. D., et al. (2020) · Endocrine · doi:10.1007/s12020-020-02515-x · Cited by 50
Psychological factors affecting COVID-19 vaccine acceptance in Indonesia
Yanto, T. A., Octavius, G. S., Heriyanto, R. S., Ienawi, C., Nisa, H., & Pasai, H. E. (2021) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-021-00436-8 · Cited by 50
Sex-disaggregated data in COVID-19 vaccine trials
Vijayasingham, L., Bischof, E. Y., & Wolfe, J. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00384-6 · Cited by 48
Valanparambil, R. M., Carlisle, J. W., Linderman, S. L., Akhtar, A., Millett, R. L., Lai, L., Chang, A., McCook‐Veal, A. A., Switchenko, J. M., Nasti, T. H., et al. (2022) · Journal of Clinical Oncology · doi:10.1200/jco.21.02986 · Cited by 48
A review of vaccine effects on women in light of the COVID-19 pandemic
Chang, W. (2020) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2020.09.006 · Cited by 46
Walsh, J. C., Comar, M., Folan, J., Williams, S., & Kola, S. (2022) · Acta Psychologica · doi:10.1016/j.actpsy.2022.103550 · Cited by 46
Lounis, M., Rais, M. A., Bencherit, D., Aouissi, H. A., Oudjedi, A., Klugarová, J., Pokorná, A., Klugar, M., & Riad, A. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.896343 · Cited by 45
Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
Kang, Y. M., Minn, D., Lim, J., Lee, K.-D., Jo, D. H., Choe, K. W., Kim, M. J., Kim, J. M., & Kim, K. N. (2021) · Journal of Korean Medical Science · doi:10.3346/jkms.2021.36.e311 · Cited by 45
Duijster, J. W., Lieber, T., Pacelli, S., van Balveren, L., Ruijs, L. S., Raethke, M., Kant, A. C., & van Hunsel, F. P. A. M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1078736 · Cited by 44
Metcalf, C. J. E., & Graham, A. L. (2018) · Nature Communications · doi:10.1038/s41467-018-06793-y · Cited by 42
Ursin, R. L., Dhakal, S., Liu, H., Jayaraman, S., Park, H.-S., Powell, H. R., Sherer, M. L., Littlefield, K. E., Fink, A. L., Ma, Z., et al. (2022) · mBio · doi:10.1128/mbio.01839-22 · Cited by 41
Self-citationHumoral response to two doses of BNT162b2 vaccination in people with HIV
Heftdal, L. D., Knudsen, A. D., Hamm, S. R., Hansen, C. B., Møller, D. L., Pries‐Heje, M. M., Fogh, K., Hasselbalch, R. B., Jarlhelt, I., Pérez‐Alós, L., et al. (2021) · Journal of Internal Medicine · doi:10.1111/joim.13419 · Cited by 38
Salciccia, S., Giudice, F. D., Eisenberg, M. L., Mastroianni, C. M., BERARDINIS, E. D., Ricciuti, G. P., Viscuso, P., Zingaropoli, M. A., Pasculli, P., Ciardi, M. R., et al. (2021) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/20420188211010105 · Cited by 38
Balle, C., Armistead, B., Kiravu, A., Song, X., Happel, A., Hoffmann, A. A., Kanaan, S. B., Nelson, J. L., Gray, C. M., Jaspan, H. B., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci148826 · Cited by 38
A population-based cohort study of sex and risk of severe outcomes in covid-19
Sieurin, J., Brandén, G., Magnusson, C., Hergens, M., & Kosidou, K. (2022) · European Journal of Epidemiology · doi:10.1007/s10654-022-00919-9 · Cited by 43
Metadata
- Authors
- Flanagan, K. L., Fink, A. L., Plebanski, M., & Klein, S. L.
- Affiliations
- Monash University (AU)
- Johns Hopkins University (US)
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2017-10-06
- Volume
- 33
- Issue
- 1
- Pages
- 577-599
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2609522512
- Cited by
- 508
- References
- 166
- Citations by year
- 2026: 36 · 2025: 42 · 2024: 83 · 2023: 65 · 2022: 106 · 2021: 87 · 2020: 55 · 2019: 18 · 2018: 13 · 2017: 1
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- cc-by
- Locations
- Annual Review of Cell and Developmental Biology (publishedVersion)
- PubMed (publishedVersion)
- RMIT Research Repository (RMIT University Library) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Keywords
- sex differences, gender differences, vaccine response, vaccine adverse events, antibody response, vaccine acceptance, life course, sex hormones, vaccine immunogenicity, vaccine safety
- MeSH terms
- Aging, Female, Humans, Male, Sex Characteristics, Vaccination, Vaccines, Epigenesis, Genetic
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