The DOI matches its Crossref record; 133 of the 133 references it cites were found in a registry or an index.
An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm
Abstract
The innate immune system consists of a cellular and a humoral arm. Pentraxins (e.g., the short pentraxin C reactive protein and the long pentraxin PTX3) are key components of the humoral arm of innate immunity which also includes complement components, collectins, and ficolins. In response to microorganisms and tissue damage, neutrophils, macrophages, and dendritic cells are major sources of fluid-phase pattern-recognition molecules (PRMs) belonging to different molecular classes. Humoral PRMs in turn interact with and regulate cellular effectors. Effector mechanisms of the humoral innate immune system include activation and regulation of the complement cascade; agglutination and neutralization; facilitation of recognition via cellular receptors (opsonization); and regulation of inflammation. Thus, the humoral arm of innate immunity is an integrated system consisting of different molecules and sharing functional outputs with antibodies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“CRP, SAP and PTX3 participate in innate immune responses against extracellular and intracellular pathogens through activation and regulation of the complement cascade, microorganism opsonisation and agglutination. Moreover, they take part in inflammation and clearance of apoptotic cells (Bottazzi et al. 2010).”
From Neuronal pentraxins as biomarkers of synaptic activity: from physiological functions to pathological changes in neurodegeneration (2022) · cites this paper as Bottazzi et al. 2010
Citations
Cites
C-reactive protein: a critical update
Pepys, M. B., & Hirschfield, G. M. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18921 · Cited by 4,694
C-reactive protein: a critical update
Pepys, M. B., & Hirschfield, G. M. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200318921 · Cited by 3,436
Ogden, C. A., deCathelineau, A. M., Hoffmann, P. R., Bratton, D. L., Ghebrehiwet, B., Fadok, V. A., & Henson, P. M. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.6.781 · Cited by 1,148
Serum amyloid A, the major vertebrate acute‐phase reactant
Uhlar, C., & Whitehead, A. S. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00657.x · Cited by 1,115
Immunoregulatory functions of surfactant proteins
Wright, J. R. (2005) · Nature reviews. Immunology · doi:10.1038/nri1528 · Cited by 966
Garlanda, C., Bottazzi, B., Bastone, A., & Mantovani, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115756 · Cited by 842
Self-citationGenetically elevated C-reactive protein and ischemic vascular disease
Zacho, J., Tybjærg-Hansen, A., Jensen, J. S., Grande, P., Sillesen, H., & Nordestgaard, B. G. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0707402 · Cited by 839
Collectins and Ficolins: Humoral Lectins of the Innate Immune Defense
Holmskov, U., Thiel, S., & Jensenius, J. C. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.140954 · Cited by 762
Complement evasion by human pathogens
Lambris, J. D., Ricklin, D., & Geisbrecht, B. V. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1824 · Cited by 720
Evolution of the lectin–complement pathway and its role in innate immunity
Fujita, T. (2002) · Nature reviews. Immunology · doi:10.1038/nri800 · Cited by 697
Research works printed but not linked: 2
- May L, 2009, Biol. Reprod.
- Borron P, 1998, Am. J. Physiol., 275, L679
Cited by
Sorted by citations
Items 301–400 of 597
Redox Proteomics Applied to the Thiol Secretome
Ghezzi, P., & Chan, P. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6732 · Cited by 17
Qin, S., Chen, X., Gao, M., Zhou, J., & Li, X. (2017) · Inflammation · doi:10.1007/s10753-017-0626-1 · Cited by 17
Scuderi, S. A., Ardizzone, A., Salako, A. E., Pantò, G., Luca, F. D., Esposito, E., & Capra, A. P. (2024) · Cancers · doi:10.3390/cancers16091637 · Cited by 16
Luo, P., Zhang, H., Liang, Y., Li, X., Wen, Z., Xia, C., Lan, X., Yang, Y., Xiong, Y., Huang, J., et al. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166807 · Cited by 16
Jiang, P., Luo, L., Li, X., Cai, K., Chen, S., Teng, D., Wang, J., Wu, B., Li, S., & Cai, J. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113604 · Cited by 16
Jakab, L. (2015) · Orvosi Hetilap · doi:10.1556/650.2015.30190 · Cited by 16
Extracellular pattern recognition molecules in health and diseases
Zhang, P., Liu, X., & Cao, X. (2014) · Cellular and Molecular Immunology · doi:10.1038/cmi.2014.81 · Cited by 18
Fluid phase recognition molecules in neutrophil-dependent immune responses
Jaillon, S., Ponzetta, A., Magrini, E. I., Barajon, I., Barbagallo, M., Garlanda, C., & Mantovani, A. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.005 · Cited by 16
Self-citationLiu, L., & Dang, Y. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.12.088 · Cited by 16
Secretory quality control constrains functional selection-associated protein structure innovation
Cheng, B., Lv, J., Liang, Y., Zhu, L., Huang, X.-P., Li, H., Potempa, L. A., Ji, S., & Wu, Y. (2022) · Communications Biology · doi:10.1038/s42003-022-03220-3 · Cited by 16
Anand, S., Pakkasjärvi, N. A., Bajpai, M., Krishnan, N., Goswami, C., Suominen, J., Yadav, D. K., & Goel, P. (2022) · Pediatric Surgery International · doi:10.1007/s00383-022-05149-4 · Cited by 16
Petrušić, V., Zivkovic, I. P., Stojanović, M., Stojićević, I., Marinković, E., Inić‐Kanada, A., & Dimitijević, L. (2011) · Immunologic Research · doi:10.1007/s12026-011-8236-8 · Cited by 16
Serum levels of long pentraxin PTX3 in patients with polymyalgia rheumatica.
Pulsatelli, L., Peri, G., Macchioni, P., Boiardi, L., Salvarani, C., Cantini, F., Mantovani, A., & Melicòni, R. (2010) · PubMed · Cited by 16
Self-citationObstructive sleep apnoea and cardiovascular disease: a literature review
Assallum, H., Song, T.-Y., Aronow, W. S., & Chandy, D. (2019) · Archives of Medical Science · doi:10.5114/aoms.2019.88558 · Cited by 17
Pentraxin 3 deficiency ameliorates the severity of osteoarthritis and alleviates inflammation
Qiu, C., Liu, J., Li, J., Di, D., Liu, T., Liu, T., Wang, X., Zhao, Y., Wang, L., & Liu, X. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.08.001 · Cited by 15
The pentraxin family in autoimmune disease
Li, Y., Zhang, S., Liu, J., Zhang, N., Zhang, N., Cheng, Q., Zhang, H., & Wu, X. (2023) · Clinica Chimica Acta · doi:10.1016/j.cca.2023.117592 · Cited by 16
Stravalaci, M., Davi, F., Parente, R., Gobbi, M., Bottazzi, B., Mantovani, A., Day, A. J., Clark, S. J., Romano, M. R., & Inforzato, A. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.591908 · Cited by 16
Self-citationQiu, C., Han, Y., Zhang, H., Liu, T., Hou, H., Luo, D., Yu, M., Bian, K., Zhao, Y., & Xiao, X. (2021) · International Journal of Medical Sciences · doi:10.7150/ijms.54787 · Cited by 15
Hu, X. L., Zhou, J., Chen, X., Zhou, Y., Song, X., Cai, B., Zhang, J., Lu, X., & Ying, B. (2016) · Scientific Reports · doi:10.1038/srep28530 · Cited by 15
Grahnert, A., Weiss, R., Schilling, E., Stanslowsky, N., Sack, U., & Hauschildt, S. (2019) · Journal of Innate Immunity · doi:10.1159/000495528 · Cited by 15
Serum pentraxin 3 is a novel marker in Crohn’s disease
Chen, J., XU, X., Xia, L., Xi, X., LIU, B., & Yang, M. (2012) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3451 · Cited by 14
Marschner, J. A., Mulay, S. R., Steiger, S., Anguiano, L., Zhao, Z., Boor, P., Rahimi, K., Inforzato, A., Garlanda, C., Mantovani, A., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02173 · Cited by 15
Self-citationCirculating pentraxin 3 in severe COVID‐19 or other pulmonary sepsis
Protti, A., Meessen, J. M. T. A., Bottazzi, B., Garlanda, C., Milani, A., Bacci, M., Mantovani, A., Cecconi, M., Latini, R., & Caironi, P. (2021) · European Journal of Clinical Investigation · doi:10.1111/eci.13530 · Cited by 14
Self-citationAcidic pH promotes oxidation-induced dissociation of C-reactive protein
Li, S., Feng, J.-R., Zhou, H., Zhang, C., Lv, G.-B., Tan, Y.-B., Ge, Z.-B., & Wang, M. (2018) · Molecular Immunology · doi:10.1016/j.molimm.2018.09.021 · Cited by 14
PTX3 Effects on Osteogenic Differentiation in Osteoporosis: An In Vitro Study
Greggi, C., Cariati, I., Onorato, F., Iundusi, R., Scimeca, M., & Tarantino, U. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115944 · Cited by 14
PTX3 orchestrates tissue repair
Doni, A., Garlanda, C., & Mantovani, A. (2015) · Oncotarget · doi:10.18632/oncotarget.5453 · Cited by 14
Self-citationKamal, M. A., Siddiqui, I., Belgiovine, C., Barbagallo, M., Paleari, V., Pistillo, D., Chiabrando, C., Schiarea, S., Bottazzi, B., Leone, R., et al. (2022) · Cancers · doi:10.3390/cancers14112653 · Cited by 13
Self-citationRole of long pentraxin PTX3 in cancer
Li, D., Hao, Z., Nan, Y., & Chen, Y. (2023) · Clinical and Experimental Medicine · doi:10.1007/s10238-023-01137-7 · Cited by 13
Complement-pentraxins synergy: Navigating the immune battlefield and beyond
Ma, Y. J., Parente, R., Zhong, H., Sun, Y., Garlanda, C., & Doni, A. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115878 · Cited by 16
Self-citationHamar, P. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25063435 · Cited by 13
Antibacterial effect of porcine PTX3 against Streptococcus suis type 2 infection
Xu, J., Mu, Y., Zhang, Y., Dong, W., Zhu, Y., Ma, J., Song, W., Pan, Z., Lu, C., & Yao, H. (2015) · Microbial Pathogenesis · doi:10.1016/j.micpath.2015.09.011 · Cited by 13
Complement 9 in amyloid deposits
Lux, A., Gottwald, J., Behrens, H., Daniel, C., Amann, K., & Röcken, C. (2021) · Amyloid · doi:10.1080/13506129.2021.1932799 · Cited by 13
Porte, R., Silva-Gomes, R., Théroude, C., Parente, R., Asgari, F., Sironi, M., Pasqualini, F., Valentino, S., Asselta, R., Recordati, C., et al. (2023) · eLife · doi:10.7554/elife.78601 · Cited by 15
Self-citationWu, S., Rau, C., Kuo, P., Shih, F.-Y., Lin, H.-P., Wu, Y.-C., Hsieh, T.-M., Liu, H.-T., & Hsieh, C. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s324056 · Cited by 13
Becerir, T., Yüksel, S., Evrengül, H., Ergin, A., & Enli, Y. (2019) · International Urology and Nephrology · doi:10.1007/s11255-019-02102-8 · Cited by 14
PTX3 acts as an extrinsic oncosuppressor
Bonavita, E., Mantovani, A., & Garlanda, C. (2015) · Oncotarget · doi:10.18632/oncotarget.4845 · Cited by 13
Self-citationAbsence of FcγRIII Results in Increased Proinflammatory Response in FcγRIII-KO Cardiac Recipients
Sunay, M. M. E., Fox-Talbot, K., Velidedeoğlu, E., Baldwin, W. M., & Wasowska, B. A. (2013) · Transplantation · doi:10.1097/tp.0b013e31829c2455 · Cited by 12
“Regression to the truth”: lessons learned from negative IPF trials
Trachalaki, A., Lindahl, A. L., Petrarulo, S., & Margaritopoulos, G. A. (2025) · Breathe · doi:10.1183/20734735.0260-2024 · Cited by 15
Development and translation of novel therapeutics targeting tumor-associated macrophages
Kosoff, D., & Lang, J. M. (2018) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2018.10.010 · Cited by 12
Jeon, J., Lee, Y., Yu, H., & Ha, U. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094652 · Cited by 12
Li, J., Bai, H., Yin, X., Wu, Z., Qiu, L., Wei, X., Zeng, Q., Mu, L., & Ye, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169468 · Cited by 12
Serum Pentraxin 3 as Promising Biomarker for the Long-Lasting Inflammatory Response of COVID-19
Capra, A. P., Crupi, L., Pantò, G., Repici, A., Calapai, F., Squeri, R., Ardizzone, A., & Esposito, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814195 · Cited by 12
Lawrence, L. H. (2011) · Frontiers in bioscience · doi:10.2741/3890 · Cited by 12
Recurrent mutations at C-reactive protein gene promoter SNP position −286 in human cancers
Wang, M., Zhou, H., Zhang, S., Hui, F., Zhu, W., Su, H., Guo, H., Li, X.-W., Ji, S., & Wu, Y. (2014) · Cell Research · doi:10.1038/cr.2014.7 · Cited by 12
Effects of C-reactive protein on the neutrophil respiratory burst in vitro
Ling, M. R., Chapple, I., Creese, A. J., & Matthews, J. B. (2013) · Innate Immunity · doi:10.1177/1753425913493199 · Cited by 12
Mora-Cartín, R., Chacón‐Díaz, C., Gutiérrez-Jiménez, C., Gurdián-Murillo, S., Lomonte, B., Chaves‐Olarte, E., Calvo, E. B., & Moreno, E. (2016) · Infection and Immunity · doi:10.1128/iai.00137-16 · Cited by 12
Tumor endothelial cells express high pentraxin 3 levels
Hida, K., Maishi, N., Kawamoto, T., Akiyama, K., Ohga, N., Hida, Y., Yamada, K., Hojo, T., Kikuchi, H., Sato, M., et al. (2016) · Pathology International · doi:10.1111/pin.12474 · Cited by 12
Mohammad, M. A., Noč, M., Lang, I. M., Holzer, M. S., Clemmensen, P. M., Jensen, U. J., Metzler, B., & Erlinge, D. (2017) · Therapeutic Hypothermia and Temperature Management · doi:10.1089/ther.2016.0041 · Cited by 12
Chen, W., Pilling, D., & Gomer, R. H. (2017) · BMC Immunology · doi:10.1186/s12865-017-0230-z · Cited by 12
Circulating Pentraxin3-Specific B Cells Are Decreased in Lupus Nephritis
Gatto, M., Wiedemann, A., Nomovi, N., Reiter, K., Schrezenmeier, E. V., Rose, T., Szelinski, F., Lino, A. C., Valentino, S., Ghirardello, A., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00029 · Cited by 12
Tsai, Y.-J., Ma, M., Wu, P., & Wu, W.-B. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30657 · Cited by 9
Matan, D., Mobarrez, F., Löfström, U., Corbascio, M., Ekström, M., Hage, C., Lyngå, P., Persson, B., Eriksson, M. J., Linde, C. M., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.952974 · Cited by 11
Vasishta, S., Ammankallu, S., Poojary, G., Gomes, S. M., Ganesh, K., Umakanth, S., Adiga, P. K., Upadhya, D., Prasad, T. S. K., & Joshi, M. B. (2024) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2024.106664 · Cited by 11
Duan, W., Li, T., & Liu, R. H. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104864 · Cited by 11
Advances in understanding the role of pentraxin-3 in lung infections
Ma, L., Li, D.-M., Wen, Y.-Y., & Shi, D.-M. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1575968 · Cited by 11
Is pentraxin 3 a cardiovascular marker in patients with chronic Chagas disease?
Lidani, K. C. F., Beltrame, M. H., Luz, P. R., Sandri, T. L., Nisihara, R., & Messias-Reason, I. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.04.106 · Cited by 11
Holmgren, A., Ljungberg, J., Hultdin, J., Johansson, B. H., Bergdahl, I. A., Näslund, U., & Söderberg, S. (2020) · Open Heart · doi:10.1136/openhrt-2020-001325 · Cited by 11
Circulating Pentraxin-3 Levels in Patients with Systemic Lupus Erythematosus: A Meta-Analysis
Wu, Q., Guan, S., Dan, Y., Zhao, C., Mao, Y., Liu, L.-N., Li, X., Wang, D., & Pan, H. (2019) · Biomarkers in Medicine · doi:10.2217/bmm-2019-0161 · Cited by 11
Rodrigues, P. D. S., Picco, N., Morgan, B. P., & Ghazal, P. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2021.1851186 · Cited by 11
STAT3 Activates the Pentraxin 3 Gene in Chronic Lymphocytic Leukemia Cells
Rozovski, U., Veletić, I., Harris, D., Li, P., Liu, Z., Jain, P., Manshouri, T., Ferrajoli, A., Burger, J. A., Bose, P., et al. (2022) · The Journal of Immunology · doi:10.4049/jimmunol.2101105 · Cited by 11
Bousquet, E., Chenevier‐Gobeaux, C., Jaworski, T., Torres-Villaros, H., Zola, M., Mantel, I., Kowalczuk, L., Matet, A., Daruich, A., Zhao, M., et al. (2023) · Ophthalmology Science · doi:10.1016/j.xops.2023.100278 · Cited by 11
Huang, S.-T. J., Huang, C., Huang, Y., Cheng, J., Yu, Y.-C., Lai, J.-C., Hung, Y., Chang, C., & Shiu, L. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1158527 · Cited by 11
Pentraxin 3 exacerbates psoriasiform dermatitis through regulation of macrophage polarization
Liu, J., Qiu, C., Zhou, Z., Li, J., Zhen, Y., Wang, R., Zhuang, Y., & Zhang, F. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.111805 · Cited by 11
Protection by natural IgG: a sweet partnership with soluble lectins does the trick!
Puga, I., & Cerutti, A. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.235 · Cited by 11
Is Pentraxin 3 a New Cardiovascular Risk Marker in Polycystic Ovary Syndrome?
Sarı, U., Kaygusuz, İ., & Kafalı, H. C. (2014) · Gynecologic and Obstetric Investigation · doi:10.1159/000363744 · Cited by 11
A heterogén glikoproteinszerkezetek biológiai szerepe
Jakab, L. (2016) · Orvosi Hetilap · doi:10.1556/650.2016.30436 · Cited by 11
Latta, V. D., Cabiati, M., Burchielli, S., Frenzilli, G., Bernardeschi, M., Cecchettini, A., Viglione, F., Morales, M., & Ry, S. D. (2017) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2017.05.016 · Cited by 11
Yoshida, M., Oishi, H., Martinu, T., Hwang, D. M., Takizawa, H., Sugihara, J., McKee, T. D., Bai, X., Guana, Z., Lua, C., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.23902 · Cited by 11
Sweet turning bitter: Carbohydrate sensing of complement in host defence and disease
Hevey, R., Pouw, R. B., Harris, C. L., & Ricklin, D. (2020) · British Journal of Pharmacology · doi:10.1111/bph.15307 · Cited by 11
Li, A., Zhao, F., Yang, T., Zhao, Y., Liu, H., Yang, S., & Zhu, X. (2022) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2021.0183 · Cited by 11
Hexameric immunoglobulin M in humans: Desired or unwanted?
Petrušić, V., Zivkovic, I. P., Stojanović, M., Stojićević, I., Marinković, E., & Dimitrijević, L. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.08.018 · Cited by 11
PTX3 is expressed in terminal lymphatics and shapes their organization and function
Doni, A., Sironi, M., Prete, A. D., Pasqualini, F., Valentino, S., Cuccovillo, I., Parente, R., Calvi, M., Tosoni, A., Vago, G. G., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1426869 · Cited by 10
Self-citationVisceral Adipose Tissue: A New Target Organ in Virus-Induced Type 1 Diabetes
Zipris, D. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.702506 · Cited by 10
C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms
Fu, Y., Liu, H., Li, K., Wei, P., Alam, N., Deng, J., Li, M., Wu, H., He, X., Hou, H., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1233807 · Cited by 10
Soluble Human Lectins at the Host–Microbe Interface
Peiffer, A. L., Dugan, A. E., & Kiessling, L. L. (2024) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-062917-012322 · Cited by 10
PAMPer and tRIGer: ligand-induced activation of RIG-I
Bowzard, J. B., Davis, W. G., Jeisy-Scott, V., Ranjan, P., Gangappa, S., Fujita, T., & Sambhara, S. R. (2011) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2011.03.003 · Cited by 10
Artesunate: A natural product-based immunomodulator involved in human complement
Song, L., Ge, T., Li, Z., Sun, J., Li, G., Sun, Y., Fang, L., Ma, Y. J., & Garred, P. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111234 · Cited by 10
Wang, M., Zhang, C., Zhou, H., Ge, Z.-B., Su, C.-C., Lou, Z.-H., Zhang, X., Xu, T., Li, S., Zhu, L., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102160 · Cited by 10
Larsson, K., Höglund, M., Larsson, A. O., Thulin, M., & Karlsson, T. (2020) · Growth Factors · doi:10.1080/08977194.2021.1932870 · Cited by 9
Immune characterization of long pentraxin 3 in pigs infected with influenza virus
Crisci, E., Fraile, L. J., Valentino, S., Martínez-Guinó, L., Bottazzi, B., Mantovani, A., & Montoya, M. (2013) · Veterinary Microbiology · doi:10.1016/j.vetmic.2013.10.004 · Cited by 9
Self-citationHan, Q., Deng, H., Fan, X., Wang, X., Zhang, X., Zhang, K., Li, N., Lv, Y., & Liu, Z. (2021) · Journal of Hepatocellular Carcinoma · doi:10.2147/jhc.s337936 · Cited by 9
Natural Inhibitors of Snake Venom Metallopeptidases
Neves‐Ferreira, A. G. C., Valente, R. H., Domont, G. B., & Perales, J. (2017) · Toxinology · doi:10.1007/978-94-007-6452-1_19 · Cited by 9
Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia
Kirschner, F., Reppe, K., Andresen, N., Witzenrath, M., Ebstein, F., & Kloetzel, P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153847 · Cited by 9
Batista, N. V., Barbagallo, M., de Oliveira, V. L. S., Castro‐Gomes, T., de Oliveira, R. D. R., Louzada‐Júnior, P., Pinheiro, G. D. R. C., Mantovani, A., Teixeira, M. M., Garlanda, C., et al. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1701531 · Cited by 10
Self-citationJanků, P., Kacerovský, M., Zedníková, B., Andrýs, C., Koláčková, M., Drahošová, M., Plíšková, L., Žemličková, H., Gerychová, R., Šimetka, O., et al. (2019) · Fetal Diagnosis and Therapy · doi:10.1159/000499482 · Cited by 9
Fragoso-Saavedra, M., & Vega‐López, M. A. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.4mr0320-488r · Cited by 9
Gupta, S. K., Wilson, T., Maclean, P. H., Rehm, B. H. A., Heiser, A., Buddle, B. M., & Wedlock, D. N. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1087015 · Cited by 9
Zeybek, S., Tepeli, E., Çetin, G. O., Caner, V., Şenol, H., Yildirim, B., & Bağcı, G. (2019) · Balkan Journal of Medical Genetics · doi:10.2478/bjmg-2019-0002 · Cited by 8
Connective tissue and inflammation
Jakab, L. (2014) · Orvosi Hetilap · doi:10.1556/oh.2014.29848 · Cited by 8
The impact of vaccines and vaccinations: Challenges and opportunities for modelers
Curtiss, R., & Curtiss, R., III (2011) · Mathematical Biosciences & Engineering · doi:10.3934/mbe.2011.8.77 · Cited by 8
Smith, S. M., & Melrose, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030497 · Cited by 8
Increased Circulating Pentraxin 3 Levels in Patients with Rheumatoid Arthritis: A Meta-analysis
Guan, S., Chen, Y., Shao, M., Yang, H., Xu, W., Shuai, Z., Zhao, H., Zhao, D., & Pan, F. (2022) · Current Pharmaceutical Design · doi:10.2174/1381612828666220614155037 · Cited by 8
Engineering Escherichia coli-Derived Nanoparticles for Vaccine Development
Tang, S., Zhao, C., & Zhu, X. (2024) · Vaccines · doi:10.3390/vaccines12111287 · Cited by 7
Wyskida, K., Franik, G., Pohl, N., Markuszewski, L., Owczarek, A. J., Madej, P., Chudek, J. T., & Olszanecka‐Glinianowicz, M. (2019) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365513.2019.1637535 · Cited by 7
Wang, Y., Chen, W., Ding, S., Wang, W., & Wang, C. (2023) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2023.105064 · Cited by 8
Belló-Pérez, M., Adamek, M., Coll, J. M., Figueras, A. J., Novoa, B., & Falcó, A. (2021) · Biology · doi:10.3390/biology10020078 · Cited by 7
Shen, Z.-Y., Zheng, Y., Pecsok, M. K., Wang, K., Li, W., Gong, M., Wu, F., & Zhang, L. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.589200 · Cited by 8
A perspective on the 2009 A/H1N1 influenza pandemic in Mexico
Acuña-Soto, R., Castaňeda-Davila, L., & Chowell, G. (2011) · Mathematical Biosciences & Engineering · doi:10.3934/mbe.2011.8.223 · Cited by 8
Chaves, A. F. A., Barros, B. C. S. C., Cosenza‐Contreras, M., Morone, M. S. L. C., Sachetto, A. T. A., Pinter, N., Schmid, M., Santoro, M. L., Schilling, O., & Serrano, S. M. T. (2025) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2025.101023 · Cited by 6
Riedelová, Z., Pereira, A. D. L. S., Daza, D. F. D., Májek, P., Dyčka, F., & Riedel, T. (2024) · Macromolecular Bioscience · doi:10.1002/mabi.202300558 · Cited by 6
Metadata
- Authors
- Bottazzi, B., Doni, A., Garlanda, C., & Mantovani, A.
- Affiliations
- IRCCS Humanitas Research Hospital (IT)
- Laboratory for Immunology and Inflammation, IRCCS Istituto Clinico Humanitas, Rozzano (Milano) 20089, Italy;, ,
- University of Milan (IT)
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2010-03-01
- Volume
- 28
- Issue
- 1
- Pages
- 157-183
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2160125610
- Cited by
- 592
- References
- 133
- Citations by year
- 2026: 11 · 2025: 27 · 2024: 34 · 2023: 32 · 2022: 44 · 2021: 42 · 2020: 40 · 2019: 35 · 2018: 28 · 2017: 36 · 2016: 48 · 2015: 38 · 2014: 45 · 2013: 45 · 2012: 30
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Biomarkers in Disease Mechanisms
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Immunology and Microbiology › Immunology › Complement system in diseases
- Keywords
- pentraxins, C-reactive protein, pentraxin 3, pattern recognition molecules, complement system, collectins, ficolins, opsonization, agglutination, neutralization, inflammation regulation, immunoglobulins, neutrophils, macrophages, dendritic cells
- MeSH terms
- Animals, Antibodies, C-Reactive Protein, Humans, Immunity, Innate, Ligands, Immunity, Humoral
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review