The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The RNA Polymerase II Core Promoter
Abstract
▪ Abstract The events leading to transcription of eukaryotic protein-coding genes culminate in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which can extend ∼35 bp upstream and/or downstream of this site, plays a central role in regulating initiation. Specific DNA elements within the core promoter bind the factors that nucleate the assembly of a functional preinitiation complex and integrate stimulatory and repressive signals from factors bound at distal sites. Although core promoter structure was originally thought to be invariant, a remarkable degree of diversity has become apparent. This article reviews the structural and functional diversity of the RNA polymerase II core promoter.
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Citations
Cites
DNA methylation patterns and epigenetic memory
Bird, A. (2002) · Genes & Development · doi:10.1101/gad.947102 · Cited by 7,124
Transcriptional coactivator complexes.
Näär, A. M., Lemon, B. D., & Tjian, R. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.475 · Cited by 571
The enhanceosome and transcriptional synergy.
Carey, M. (1998) · Cell · doi:10.1016/s0092-8674(00)80893-4 · Cited by 553
Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53
Mack, D. H., Vartikar, J., Pipas, J. M., & Laimins, L. A. (1993) · Nature · doi:10.1038/363281a0 · Cited by 322
Enhancer–promoter specificity mediated by DPE or TATA core promoter motifs
Butler, J. E. F., & Kadonaga, J. T. (2001) · Genes & Development · doi:10.1101/gad.924301 · Cited by 265
Self-citationPromoter specificity mediates the independent regulation of neighboring genes.
Merli, C., Bergstrom, D. E., Cygan, J. A., & Blackman, R. K. (1996) · Genes & Development · doi:10.1101/gad.10.10.1260 · Cited by 115
Cited by
The ENCODE Project Consortium (2007) · Nature · doi:10.1038/nature05874 · Cited by 5,223
Heintzman, N. D., Stuart, R. K., Hon, G., Fu, Y., Ching, C. W., Hawkins, R. D., Barrera, L. O., Van Calcar, S., Qu, C., Ching, K. A., et al. (2007) · Nature Genetics · doi:10.1038/ng1966 · Cited by 3,398
Genome-wide analysis of mammalian promoter architecture and evolution
Carninci, P., Sandelin, A., Lenhard, B., Katayama, S., Shimokawa, K., Ponjavic, J., Semple, C. A. M., Taylor, M. S., Engström, P. G., Frith, M. C., et al. (2006) · Nature Genetics · doi:10.1038/ng1789 · Cited by 1,350
Transcription regulation and animal diversity
Levine, M., & Tjian, R. (2003) · Nature · doi:10.1038/nature01763 · Cited by 1,309
Transcriptional Regulatory Elements in the Human Genome
Maston, G. A., Evans, S. K., & Green, M. R. (2006) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.7.080505.115623 · Cited by 937
Metadata
- Authors
- Smale, S. T., & Kadonaga, J. T.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2003-06
- Volume
- 72
- Issue
- 1
- Pages
- 449-479
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2170698318
- Cited by
- 1,133
- References
- 6
- FWCI
- 3.67
- Type
- journal article
- Language
- en
- Open access
- closed
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