The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Small RNAs and Their Roles in Plant Development
Open accessAbstract
Small RNAs of 20–30 nucleotides guide regulatory processes at the DNA or RNA level in a wide range of eukaryotic organisms. Many, although not all, small RNAs are processed from double-stranded RNAs or single-stranded RNAs with local hairpin structures by RNase III enzymes and are loaded into argonaute-protein-containing effector complexes. Many eukaryotic organisms have evolved multiple members of RNase III and the argonaute family of proteins to accommodate different classes of small RNAs with specialized molecular functions. Some small RNAs cause transcriptional gene silencing by guiding heterochromatin formation at homologous loci, whereas others lead to posttranscriptional gene silencing through mRNA degradation or translational inhibition. Small RNAs are not only made from and target foreign nucleic acids such as viruses and transgenes, but are also derived from endogenous loci and regulate a multitude of developmental and physiological processes. Here I review the biogenesis and function of three major classes of endogenous small RNAs in plants: microRNAs, trans-acting siRNAs, and heterochromatic siRNAs, with an emphasis on the roles of these small RNAs in developmental regulation.
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Cites
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Self-citation
Cited by
The Functions of MicroRNAs: mRNA Decay and Translational Repression
Iwakawa, H.-O., & Tomari, Y. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.07.011 · Cited by 732
Posttranscriptional Regulation of MicroRNA Biogenesis in Animals
Siomi, H., & Siomi, M. C. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.03.013 · Cited by 578
The ‘how’ and ‘where’ of plant micro RNA s
Yu, Y., Jia, T., & Chen, X. (2017) · New Phytologist · doi:10.1111/nph.14834 · Cited by 459
Self-citationEpigenetic Regulation in Plants
Pikaard, C. S., & Mittelsten Scheid, O. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a019315 · Cited by 440
Cross-kingdom inhibition of breast cancer growth by plant miR159
Chin, A. R., Fong, M. Y., Somlo, G., Wu, J., Swiderski, P., Wu, X., & Wang, S. E. (2016) · Cell Research · doi:10.1038/cr.2016.13 · Cited by 426
Metadata
- Authors
- Chen, X.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2009-11-01
- Volume
- 25
- Issue
- 1
- Pages
- 21-44
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2151953896
- Cited by
- 948
- References
- 10
- FWCI
- 4.45
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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