Wnt Signaling in Neural Circuit Assembly

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568

The Wnt Signaling Pathway in Development and Disease

Logan, C. Y., & Nusse, R. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.113126 · Cited by 5,325

The Molecular Biology of Axon Guidance

Tessier‐Lavigne, M., & Goodman, C. S. (1996) · Science · doi:10.1126/science.274.5290.1123 · Cited by 3,311

Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors

Gordon, M. D., & Nusse, R. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.r600015200 · Cited by 1,333

Morphological Changes in Dendritic Spines Associated with Long-Term Synaptic Plasticity

Yuste, R., & Bonhoeffer, T. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1071 · Cited by 1,269

Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context

Mikels, A. J., & Nusse, R. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040115 · Cited by 1,244

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

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Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H., & Moon, R. T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00240-9 · Cited by 945

Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance

Dent, E. W., & Gertler, F. B. (2003) · Neuron · doi:10.1016/s0896-6273(03)00633-0 · Cited by 922

Wnt and calcium signaling: β-Catenin-independent pathways

Kohn, A. D., & Moon, R. T. (2005) · Cell Calcium · doi:10.1016/j.ceca.2005.06.022 · Cited by 730

Current status of biological treatment options in Autism Spectrum Disorder

Eapen, V., Nicholls, L. E., Spagnol, V., & Mathew, N. E. (2017) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2017.07.025 · Cited by 11

Canonical Wnt pathway and the LDL receptor superfamily in neuronal cholesterol homeostasis and function

Borrell-Pages, M., Luquero, A., Vilahur, G., Padró, T., & Badimon, L. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvad159 · Cited by 10

Life-long arsenic exposure damages the microstructure of the rat hippocampus

Niño, S. A., Chi-Ahumada, É., Carrizales, L., Estrada‐Sánchez, A. M., González-Billault, C. E., Zarazúa, S., Concha, L., & Jiménez-Capdeville, M. E. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147742 · Cited by 10

Predictive Power of “A Minima” Models in Biology

de Almeida, L. N., & Jacques Demongeot, A. (2012) · Acta Biotheoretica · doi:10.1007/s10441-012-9146-4 · Cited by 10

Role of Non-Coding RNA in Neurological Complications Associated With Enterovirus 71

Yang, F., Zhang, N., Chen, Y., Yin, J., Xu, M., Cheng, X. C., Ma, R., Meng, J., & Du, Y. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.873304 · Cited by 10

Calpain Activation by Wingless-type Murine Mammary Tumor Virus Integration Site Family, Member 5A (Wnt5a) Promotes Axonal Growth

Yang, G., Liang, B., Zhu, J. Y., & Luo, Z. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.196568 · Cited by 10

Development of Innervation to Maxillary Whiskers in Mice

Maklad, A., Conway, M., Hodges, C., & Hansen, L. A. (2010) · The Anatomical Record · doi:10.1002/ar.21194 · Cited by 10

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function

Geng, S., Paul, F., Kowalczyk, I., Raimundo, S., Sporbert, A., Mamo, T. M., & Hammes, A. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1173688 · Cited by 8

Sonic hedgehog regulates the pathfinding of descending serotonergic axons in hindbrain in collaboration with Wnt5a and secreted frizzled‐related protein 1

Xie, J., Zhao, T., & Liu, Y. (2017) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2017.11.006 · Cited by 9

Wnt-2b in the intermediate hyperpallium apicale of the telencephalon is critical for the thyroid hormone-mediated opening of the sensitive period for filial imprinting in domestic chicks (Gallus gallus domesticus)

Yamaguchi, S., Aoki, N., Matsushima, T., & Homma, K. J. (2018) · Hormones and Behavior · doi:10.1016/j.yhbeh.2018.05.011 · Cited by 9

The Extraocular Muscles Are Selectively Spared in ALS

Domellöf, F. P. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.89504 · Cited by 9

Scaling the MAPK Signaling Threshold during CNS Patterning

Plestant, C., & Anton, E. S. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.04.014 · Cited by 8

β‐Catenin regulates membrane potential in muscle cells by regulating the α2 subunit of Na,K‐ ATP ase

Zhao, C., Zhang, J., Li, K., Yang, J., Yu, H., Duan, S., Jiang, K., & Li, X. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12564 · Cited by 8

Implication of Wnt signaling in neuronal polarization

Yang, G., & Luo, Z. (2010) · Developmental Neurobiology · doi:10.1002/dneu.20851 · Cited by 8

β-Catenin Controls the Electrophysiologic Properties of Skeletal Muscle Cells by Regulating the α2 Isoform of Na+/K+-ATPase

Zhao, C., Yu, Y., Zhang, Y., Shen, J., Jiang, L., Sheng, G., Zhang, W., Lu, C., Jiang, K., Mao, S., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00831 · Cited by 8

Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice

Hu, L., Chen, Y., Yang, C., Huang, Y., Song, N., Chen, J., Sun, Y., Ding, Y., & Lang, B. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.645368 · Cited by 8

miR-140-y targets TCF4 to regulate the Wnt signaling pathway and promote embryonic feather follicle development in Hungarian white goose

Ma, J., Song, Y., Mabrouk, I., Zhou, Y., Liu, Q., Yü, J., Li, X., Xue, G., Wang, J., Yu, Z., et al. (2024) · Poultry Science · doi:10.1016/j.psj.2024.103508 · Cited by 7

Neurotoxic mechanisms of dexamethasone in SH-SY5Y neuroblastoma cells: Insights into bioenergetics, oxidative stress, and apoptosis

Elmorsy, E. M., Al-Ghafari, A. B., Doghaither, H. A. A., Fawzy, M. S., & Shehata, S. A. (2024) · Steroids · doi:10.1016/j.steroids.2024.109514 · Cited by 7

unfulfilledInteracting Genes Display Branch-Specific Roles in the Development of Mushroom Body Axons inDrosophila melanogaster

Bates, K. E., Sung, C. S., Hilson, L. G., & Robinow, S. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.113.009829 · Cited by 7

Identification of a novel de novo mutation in the CTNNB1 gene in an Iranian patient with intellectual disability

Dashti, S., Salehpour, S., Ghasemi, M., Sadeghi, H., Rostami, M., Hashemi‐Gorji, F., Mirfakhraie, R., Yassaee, V. R., & Miryounesi, M. (2022) · Neurological Sciences · doi:10.1007/s10072-022-05904-4 · Cited by 7

How are neurons wired to form functional and plastic circuits?

Stoeckli, E. T., & Zou, Y. (2009) · EMBO Reports · doi:10.1038/embor.2009.47 · Cited by 7

Wnt Signaling Regulates Ipsilateral Pathfinding in the Zebrafish Forebrain through slit3

Zhang, Q., Zhang, C., Zhang, C., & Peng, G. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.09.028 · Cited by 7

Brain Morphogenesis and Developmental Neurotoxicology

Jensen, K. F., & Olin, J. K. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809405-1.00001-8 · Cited by 7

Wnt5a Promotes Axon Elongation in Coordination with the Wnt–Planar Cell Polarity Pathway

Ahmad, S., & Attisano, L. (2024) · Cells · doi:10.3390/cells13151268 · Cited by 6

Does altering proteasomal activity and trafficking reduce the arborization mediated specific vulnerability of SNpc dopaminergic neurons of Parkinson’s disease?

Bhaskar, S., Gowda, J., Prasanna, J., & Kumar, A. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110062 · Cited by 6

LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants

Darbandi, S. F., Nelson, A. D., Pai, E. L.-L., Bender, K. J., & Rubenstein, J. L. R. (2022) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-022-09421-5 · Cited by 6

The mechanism of the WNT5A and FZD4 receptor mediated WNT/β–catenin pathway in the degeneration of ALS spinal cord motor neurons

Jiang, X., Liu, J., Guan, Y., Zhao, Z., Meng, F., Wang, X., Gao, X., Zhou, F., Chen, Y., & Wang, X. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.03.126 · Cited by 5

MTM-6, a Phosphoinositide Phosphatase, is Required to Promote Synapse Formation in Caenorhabditis elegans

Ericson, V. R., Spilker, K. A., Tugizova, M., & Shen, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0114501 · Cited by 4

The molecular mechanisms that underlie neural network assembly

Ye, B. (2022) · Medical Review · doi:10.1515/mr-2022-0011 · Cited by 4

Identification of eQTLs and differential gene expression associated with fetal programming in beef cattle

Polizel, G. H. G., César, A. S. M., Cracco, R. C., Fernandes, A. C., Reginato, G. M., Xavier, P. L. P., Mortari, I., Furlan, É., Fukumasu, H., & Santana, M. H. D. A. (2022) · Journal of Applied Genetics · doi:10.1007/s13353-022-00711-1 · Cited by 4

Autism spectrum disorder: difficulties in diagnosis and microRNA biomarkers

Martinez, B., & Peplow, P. V. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00712 · Cited by 4

Neuroprotective Effects of Resveratrol on a Mouse Model of Parkinson's Disease via the Wnt/Beta-Catenin Signaling Pathway

Dong, Y., Wang, Z., Yan, Z., Wu, C., Yang, T., & Qiu, H. (2022) · Indian Journal of Pharmaceutical Sciences · doi:10.36468/pharmaceutical-sciences.990 · Cited by 4

Wnt Signaling Roles on the Structure and Function of the Central Synapses: Involvement in Alzheimer’s Disease

Nibaldo, C., & Varela‐Nallar, L. (2013) · InTech eBooks · doi:10.5772/54606 · Cited by 2

Environmental Enrichment Repairs Structural and Functional Plasticity in the Hippocampus

Ghiglieri, V., & Calabresi, P. (2017) · Contemporary clinical neuroscience · doi:10.1007/978-3-319-52067-4_3 · Cited by 2

Axon Guidance

Piper, M., Keynes, R. J., & Cook, G. M. W. (2012) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0000799.pub3 · Cited by 2

Wnt-5a/Ca2+ pathway modulates endogenous current and oocyte structure of Xenopus laevis

Parodí, J., Mira, R. G., Martínez‐Torres, A., & Inestrosa, N. C. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150507 · Cited by 1

Eleganolone, a diterpene isolated from seaweed Bifurcaria bifurcata (Phaeophyceae, Fucales), protects neuronal cells from oxidative stress-induced damage

Martínez, M., López-Torres, B., Maximiliano, J.-E., Martínez, M., Martínez‐Larrañaga, M., Arés, I., Anadón, A., Peteiro, C., Aymerich, T., Casal-Silva, A., et al. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177977 · Cited by 1

Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae

Takagi, S., Takano, S., Kubo, T., Hashimoto, Y., Morise, S., Zeng, X., & Nose, A. (2024) · eLife · doi:10.7554/elife.98624.3 · Cited by 1

Wnt Signaling in Spinal Cord Injury

Zou, Y. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801732-6.00015-x · Cited by 1

Wnt signaling

Salinas, P. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-823672-7.00006-5 · Cited by 1

Wnt Signaling

Salinas, P. C. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397266-8.00106-x · Cited by 1

Differential Regulation of Wnt Signaling Components During Hippocampal Reorganization After Entorhinal Cortex Lesion

García‐Velázquez, L., & Arias, C. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-00870-x · Cited by 1

Low-level Chlorpyrifos Exposure Affects Synaptic Plasticity in Hippocampal NeuronsPreprint

Zhou, W., Zhang, C., Wang, P., Deng, Y., Dai, H., Qiong, X., Tian, J., Zhao, M., Wu, G., & Zhao, L. (2021) · Research Square · doi:10.21203/rs.3.rs-377989/v1 · Cited by 1

Die kritische Rolle von EPO auf das Überleben, die Funktionalität und die neuronale Differenzierung von mesenchymalen Stammzellen unter neurotoxischen Bedingungen

Schmitt, A. (2013)

The role of Wnt signalling in excitatory hippocampal synapse formation and function

Anane, D. (2012) · UCL Discovery (University College London)

A critical view on neuronal polarization: How to make a single axon?

Moorman, S. (2009) · Utrecht University Repository (Utrecht University)

Planar polarity genes and inhibition of supernumerary neurites

Colavita, A. (2012) · Worm · doi:10.4161/worm.19537

Wnt5aInducesSimultaneousCorticalAxonOutgrowthand RepulsiveAxonGuidancethroughDistinctSignaling Mechanisms

IanHutchins, B. (2009)

Network based analysis of genetic disease associations

Gilman, S. R. (2013) · doi:10.7916/d8k9370f

Dissecting the Development and Function of C. elegans Glia with Mutations of the mls-2 and vab-3 Genes

Satoshi, Y. (2025) · Digital Commons - RU (Rockefeller University) · doi:10.48496/a0yw-sr08

Morphine and Trafficking of a Mu Opioid Receptor Interacting Protein WLS

Reyes, B. A. S., Berrettini, W. H., Enman, N. M., & Bockstaele, E. J. V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800634-4.00051-2

Genetic and Chemical Dissection of BloodBrain Barrier Development in Zebrafish

Umans, R. A. (2014) · doi:10.21007/etd.cghs.2014.0329

Coordinated Action of Biological Processes during Embryogenesis Can Cause Genome-Wide Linkage Disequilibrium in the Human Genome and Influence Age-Related Phenotypes.

Culminskaya, I. V., Kulminski, A. M., & Yashin, A. I. (2016) · PubMed

Cytoskeletal Regulation and Morphogen Signaling During Synaptic Outgrowth at the Drosophila Larval Neuromuscular Junction : A Dissertation

Ramachandran, P. (2009) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/e8pg-tq46

Enhancer regulation for induced WNT3A expression during neuronal regenerationPreprint

Chang, C.-Y., Hung, J., Wu, C.-C., Liang, M.-Z., Huang, P.-Y., Li, J., Chen, H., Yet, S., Fung, K. S., Kao, C.-F., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/861153

Faculty Opinions recommendation of WNT signaling underlies the pathogenesis of neuropathic pain in rodents.

Gutstein, H. B., & Donica, C. L. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718000207.793485566

Der Einfluss rekombinanter Neuroligine auf die neuronale Reifung

Fenske, J. (2022) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-9300

Beadex, the Drosophila LIM only protein, is required for the growth of the larval neuromuscular junction and sensorimotor activitiesPreprint

Chitre, K., Kairamkonda, S., Dwivedi, M. K., Yadav, S., Kumar, V., Sikdar, S. K., & Nongthomba, U. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.20.558737

Beadex, the Drosophila LIM only protein, is required for the growth of the larval neuromuscular junction

Chitre, K., Kairamkonda, S., Dwivedi, M. K., Yadav, S., Kumar, V., Sikdar, S. K., & Nongthomba, U. (2024) · Journal of Neurophysiology · doi:10.1152/jn.00064.2024

eLife Assessment: Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae

Melnattur, K. V. (2024) · eLife · doi:10.7554/elife.98624.1.sa2

Reviewer #2 (Public Review): Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae

(2024) · eLife · doi:10.7554/elife.98624.1.sa0

Reviewer #1 (Public Review): Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae

(2024) · eLife · doi:10.7554/elife.98624.1.sa1

Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvaePreprint

Takagi, S., Takano, S., Hashimoto, Y., Morise, S., Zeng, X., & Nose, A. (2024) · eLife · doi:10.7554/elife.98624.1

Intracerebral administration of Wnt7a improves memory performance and increases synaptophysin expression in the 3xTg-AD mouse model

Colín-Martínez, E., & Arias, C. (2025) · Neuroscience Letters · doi:10.1016/j.neulet.2025.138336

Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvaePreprint

Takagi, S., Takano, S., Kubo, T., Hashimoto, Y., Morise, S., Zeng, X., & Nose, A. (2025) · eLife · doi:10.7554/elife.98624.2

Wnt signalling in the hydrozoan Hydractinia echinata

Hensel, K. (2013) · ARAN (University of Galway Research Repository) (Ollscoil na Gaillimhe – University of Galway) · doi:10.13025/16209

A study of the role of presenilin (1) in regulating synaptic function at hippocampal synapses

Yu, L. M. Y. (2010) · UCL Discovery (University College London)

Molecular Regulators of Stem Cell Fate and Tumor Development in the Cerebellum

Brun, S. N. (2014) · DukeSpace (Duke University)

Additional file 1 of LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants

Darbandi, S. F., Nelson, A. D., Pai, E. L.-L., Bender, K. J., & Rubenstein, J. L. R. (2022) · Figshare · doi:10.6084/m9.figshare.19128929

The impact of maternal vitamin D deficiency during pregnancy and lactation on autism-like behavior in offspring

Song, X.-Y., He, H.-N., Tuo, L.-J., Wang, B., Zhang, H., & Xu, D. (2026) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2026.112737 · Cited by 1

Carence précoce en donneurs de méthyles dans le cervelet : mécanismes moléculaires et épigénétiques

Willekens, J. (2017) · theses.fr (ABES) · doi:10.70675/66d487f0z6da0z4367zafc6z07b11690c9cb

LIN-44/Wnt controls developmental neurite pruning via UNC-43/CaMKII and PKC-2/PKC in Caenorhabditis elegans

Lu, M., Lin, J. S. H., Kurashina, M., & Mizumoto, K. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2619924123

A Novel Communication Mechanism Between the Presynapse and Postsynapse Through Exosomes: A Dissertation

Korkut, C. (2012) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/vqef-8314

Wnt Signaling in Vertebrate Neural Development and Function

Mulligan, K. A., & Cheyette, B. N. R. (2012) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-012-9404-x · Cited by 177

Wnt signaling: multiple functions in neural development

Ille, F., & Sommer, L. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-4552-2 · Cited by 180

WNTs in synapse formation and neuronal circuitry

Park, M., & Shen, K. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.145 · Cited by 107

Wnt Signaling in the Vertebrate Central Nervous System: From Axon Guidance to Synaptic FunctionPreprint

Salinas, P. C. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008003 · Cited by 195

Wnt Signaling in Neuromuscular Junction DevelopmentPreprint

Koles, K., & Budnik, V. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008045 · Cited by 103