Wnt and calcium signaling: β-Catenin-independent pathways

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

Rao, A., Luo, C. H., & Hogan, P. G. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.707 · Cited by 2,605 · see citing works

Wnt signaling: a common theme in animal development

Cadigan, K. M., & Nusse, R. (1997) · Genes & Development · doi:10.1101/gad.11.24.3286 · Cited by 2,567 · see citing works

A Second Canon

Veeman, M. T., Axelrod, J. D., & Moon, R. T. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00266-1 · Cited by 1,359 · see citing works

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber typePreprint

Chin, E. R., Olson, E. N., Richardson, J. A., Yang, Q., Humphries, C. G., Shelton, J. M., Wu, H., Zhu, W., Bassel‐Duby, R., & Williams, R. S. (1998) · Genes & Development · doi:10.1101/gad.12.16.2499 · Cited by 1,015 · see citing works

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

Heisenberg, C.-P., Tada, M., Rauch, G.-J., Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C., & Wilson, S. W. (2000) · Nature · doi:10.1038/35011068 · Cited by 1,013 · see citing works

The Promise and Perils of Wnt Signaling Through β-Catenin

Moon, R. T., Bowerman, B. A., Boutros, M., & Perrimon, N. (2002) · Science · doi:10.1126/science.1071549 · Cited by 970 · see citing works

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

Weeraratna, A. T., Jiang, Y., Hostetter, G. H., Rosenblatt, K. P., Duray, P. H., Bittner, M. L., & Trent, J. M. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00045-4 · Cited by 960 · see citing works

Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H., & Moon, R. T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00240-9 · Cited by 945 · see citing works

The Wnt/Ca2+ pathway

Kühl, M., Sheldahl, L. C., Park, M., Miller, J. R., & Moon, R. T. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(00)02028-x · Cited by 862 · see citing works

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation

Topol, L. Z., Jiang, X., Choi, H., Garrett-Beal, L. J., Carolan, P. J., & Yang, Y. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303158 · Cited by 724 · see citing works

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

Slusarski, D. C., Corces, V. G., & Moon, R. T. (1997) · Nature · doi:10.1038/37138 · Cited by 680 · see citing works

Xwnt11is a target ofXenopusBrachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway

Tada, M., & Smith, J. C. (2000) · Development · doi:10.1242/dev.127.10.2227 · Cited by 675 · see citing works

The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF

Ishitani, T., Ninomiya-Tsuji, J., Nagai, S.-I., Nishita, M., Meneghini, M., Barker, N., Waterman, M., Bowerman, B., Clevers, H., Shibuya, H., et al. (1999) · Nature · doi:10.1038/21674 · Cited by 624 · see citing works

Transcriptional regulation of the IL-2 gene

Jain, J. (1995) · Current Opinion in Immunology · doi:10.1016/0952-7915(95)80107-3 · Cited by 568 · see citing works

The TAK1-NLK Mitogen-Activated Protein Kinase Cascade Functions in the Wnt-5a/Ca 2+ Pathway To Antagonize Wnt/β-Catenin Signaling

Ishitani, T., Kishida, S., Hyodo‐Miura, J., Ueno, N., Yasuda, J., Waterman, M. L., Shibuyà, H., Moon, R. T., Ninomiya‐Tsuji, J., & Matsumoto, K. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.23.1.131-139.2003 · Cited by 540 · see citing works

Ca2+/Calmodulin-dependent Protein Kinase II Is Stimulated by Wnt and Frizzled Homologs and Promotes Ventral Cell Fates in Xenopus

Kühl, M., Sheldahl, L. C., Malbon, C. C., & Moon, R. T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.17.12701 · Cited by 517 · see citing works

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in aG-protein-dependent manner

Sheldahl, L. C., Park, M., Malbon, C. C., & Moon, R. T. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80310-8 · Cited by 475 · see citing works

The Zebrafish Glypican Knypek Controls Cell Polarity during Gastrulation Movements of Convergent Extension

Topczewski, J., Sepich, D. S., Myers, D. C., Walker, C., Amores, A., Lele, Z., Hammerschmidt, M., Postlethwait, J. H., & Solnica‐Krezel, L. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00005-3 · Cited by 454 · see citing works

Planar Signaling and Morphogenesis in Drosophila

Adler, P. N. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00176-4 · Cited by 443 · see citing works

Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo

Naya, F. J., Mercer, B. M., Shelton, J. M., Richardson, J. A., Williams, R. S., & Olson, E. N. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.7.4545 · Cited by 420 · see citing works

Establishment of the Dorso-ventral Axis in Xenopus Embryos Is Presaged by Early Asymmetries in β-Catenin That Are Modulated by the Wnt Signaling Pathway

Larabell, C. A., Torres, M. A., Rowning, B. A., Yost, C., Miller, J. R., Wu, M., Kimelman, D., & Moon, R. T. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.5.1123 · Cited by 407 · see citing works

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development.

Torres, M. A., Yang-Snyder, J., Purcell, S. M., DeMarais, A. A., McGrew, L. L., & Moon, R. T. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.133.5.1123 · Cited by 405 · see citing works

Modulation of Embryonic Intracellular Ca2+Signaling byWnt-5A

Slusarski, D. C., Yang-Snyder, J., Busa, W. B., & Moon, R. T. (1997) · Developmental Biology · doi:10.1006/dbio.1996.8463 · Cited by 404 · see citing works

Wnt5aandWnt5bexhibit distinct activities in coordinating chondrocyte proliferation and differentiation

Yang, Y., Topol, L. Z., Lee, H., & Wu, J. (2003) · Development · doi:10.1242/dev.00324 · Cited by 398 · see citing works

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos

Sheldahl, L. C., Slusarski, D. C., Pandur, P., Miller, J. R., Kühl, M., & Moon, R. T. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211094 · Cited by 350 · see citing works

Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells.

Shaw, K. T. Y., Ho, A. M., Raghavan, A., Kim, J. I., Jain, J., Park, J., Sharma, S., Rao, A., & Hogan, P. G. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.24.11205 · Cited by 345 · see citing works

Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue

Liang, H., Chen, Q., Coles, A. H., Anderson, S. J., Pihan, G. A., Bradley, A., Gerstein, R. M., Jurecic, R., & Jones, S. N. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00268-x · Cited by 329 · see citing works

The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation

Kilian, B., Mansukoski, H., Carreira-Barbosa, F., Ulrich, F., Tada, M., & Heisenberg, C. (2003) · Mechanisms of Development · doi:10.1016/s0925-4773(03)00004-2 · Cited by 327 · see citing works

The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos

Saneyoshi, T., Kume, S., Amasaki, Y., & Mikoshiba, K. (2002) · Nature · doi:10.1038/417295a · Cited by 322 · see citing works

A Calcineurin-NFATc3-Dependent Pathway Regulates Skeletal Muscle Differentiation and Slow Myosin Heavy-Chain Expression

Delling, U., Turečková, J., Lim, H. W., Windt, L. J. D., Rotwein, P. S., & Molkentin, J. D. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.17.6600-6611.2000 · Cited by 321 · see citing works

Role of <i>frizzled 7</i> in the regulation of convergent extension movements during gastrulation in <i>Xenopus laevis</i>

Djiane, A., Riou, J.-F., Umbhauer, M., Boucaut, J.-C., & Shi, D.-L. (2000) · Development · doi:10.1242/dev.127.14.3091 · Cited by 316 · see citing works

Runnin' with the Dvl: Proteins That Associate with Dsh/Dvl and Their Significance to Wnt Signal Transduction

Wharton, K. A. (2003) · Developmental Biology · doi:10.1006/dbio.2002.0869 · Cited by 315 · see citing works

Identification of Distinct Classes and Functional Domains of Wnts through Expression of Wild-Type and Chimeric Proteins in Xenopus Embryos

Du, S., Purcell, S. M., Christian, J. L., McGrew, L. L., & Moon, R. T. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.5.2625 · Cited by 314 · see citing works

Differential Transformation of Mammary Epithelial Cells by Wnt Genes

Wong, G. T., Gavin, B. J., & McMahon, A. P. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.6278-6286.1994 · Cited by 302 · see citing works

Essential role of non-canonical Wnt signalling in neural crest migration

Calisto, J. D., Araya, C., Marchant, L., Riaz, C. F., & Mayor, R. (2005) · Development · doi:10.1242/dev.01857 · Cited by 296 · see citing works

MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans

Meneghini, M. D., Ishitani, T., Carter, J. C., Hisamoto, N., Ninomiya-Tsuji, J., Thorpe, C. J., Hamill, D. R., Matsumoto, K., & Bowerman, B. (1999) · Nature · doi:10.1038/21666 · Cited by 293 · see citing works

Trimeric G Protein-Dependent Frizzled Signaling in Drosophila

Katanaev, V. L., Ponzielli, R., Sémériva, M., & Tomlinson, A. (2005) · Cell · doi:10.1016/j.cell.2004.11.014 · Cited by 277 · see citing works

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity

Westfall, T. A., Brimeyer, R., Twedt, J., Gladon, J., Olberding, A., Furutani‐Seiki, M., & Slusarski, D. C. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303107 · Cited by 271 · see citing works

Wnt-5a has tumor suppressor activity in thyroid carcinoma

Kremenevskaja, N., von Wasielewski, R., Rao, A., Schöfl, C., Andersson, T., & Brabant, G. E. (2005) · Oncogene · doi:10.1038/sj.onc.1208370 · Cited by 260 · see citing works

Differential transformation of mammary epithelial cells by Wnt genes.

Wong, G. T., Gavin, B. J., & McMahon, A. P. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.6278 · Cited by 249 · see citing works

Antagonistic regulation of convergent extension movements in Xenopus by Wnt/β-catenin and Wnt/Ca2+ signaling

Kühl, M., Geis, K., Sheldahl, L. C., Pukrop, T., Moon, R. T., & Wedlich, D. (2001) · Mechanisms of Development · doi:10.1016/s0925-4773(01)00416-6 · Cited by 219 · see citing works

Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas.

Jönsson, M., Dejmek, J. S., Bendahl, P., & Andersson, T. (2002) · PubMed · Cited by 212 · see citing works

TheXenopusreceptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling

Hikasa, H., Shibata, M., Hiratani, I., & Taira, M. (2002) · Development · doi:10.1242/dev.129.22.5227 · Cited by 198 · see citing works

Signaling of Rat Frizzled-2 Through Phosphodiesterase and Cyclic GMP

Ahumada, A., Slusarski, D. C., Liu, X., Moon, R. T., Malbon, C. C., & Wang, H. (2002) · Science · doi:10.1126/science.1073776 · Cited by 178 · see citing works

Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

Kaykas, A., Yang-Snyder, J., Héroux, M., Shah, K. V., Bouvier, M., & Moon, R. T. (2003) · Nature Cell Biology · doi:10.1038/ncb1081 · Cited by 174 · see citing works

Wnt signalling regulates myogenic differentiation in the developing avian wing

Anakwe, K., Robson, L. G., Hadley, J., Buxton, P., CHURCH, V. L., Allen, S., Hartmann, C., Harfe, B. D., Nohno, T., Brown, A. M. C., et al. (2003) · Development · doi:10.1242/dev.00538 · Cited by 167 · see citing works

Xenopus Cdc42 Regulates Convergent Extension Movements during Gastrulation through Wnt/Ca2+ Signaling Pathway

Choi, S., & Han, J. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0602 · Cited by 160 · see citing works

Wnt Signaling, Ca 2 + , and Cyclic GMP: Visualizing Frizzled Functions

Wang, H., & Malbon, C. C. (2003) · Science · doi:10.1126/science.1085259 · Cited by 156 · see citing works

Multiple Mechanisms for Wnt11-mediated Repression of the Canonical Wnt Signaling Pathway

Maye, P. F., Zheng, J., Li, L., & Wu, D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m311724200 · Cited by 143 · see citing works

Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells

Jönsson, M., & Andersson, T. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.11.2043 · Cited by 123 · see citing works

Frizzled signaling and cell–cell interactions in planar polarity

Adler, P. N., & Lee, H. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00263-5 · Cited by 119 · see citing works

Wnt11 Signaling Promotes Proliferation, Transformation, and Migration of IEC6 Intestinal Epithelial Cells

Ouko, L., Ziegler, T. R., Gu, L. H., Eisenberg, L. M., & Yang, V. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402877200 · Cited by 109 · see citing works

Antisensewnt-5a Mimicswnt-1-Mediated C57MG Mammary Epithelial Cell Transformation

Olson, D. J., & Gibo, D. M. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4030 · Cited by 102 · see citing works

Role of Inositol 1,4,5-Trisphosphate Receptor in Ventral Signaling in Xenopus Embryos

Kume, S., Muto, A., Inoue, T., Suga, K., Okano, H., & Mikoshiba, K. (1997) · Science · doi:10.1126/science.278.5345.1940 · Cited by 101 · see citing works

Wnt‐5a and G‐protein signaling are required for collagen‐induced DDR1 receptor activation and normal mammary cell adhesion

Dejmek, J. S., Dib, K., Jönsson, M., & Andersson, T. (2002) · International Journal of Cancer · doi:10.1002/ijc.10752 · Cited by 88 · see citing works

Activation of Gβγ signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation

Penzo‐Méndez, A., Umbhauer, M., Djiane, A., Boucaut, J., & Riou, J. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00067-8 · Cited by 84 · see citing works

Requirement for intracellular calcium modulation in zebrafish dorsal–ventral patterning

Westfall, T. A., Hjertos, B., & Slusarski, D. C. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00209-4 · Cited by 80 · see citing works

Endothelial Cells Stimulate T Cell NFAT Nuclear Translocation in the Presence of Cyclosporin A: Involvement of the wnt/Glycogen Synthase Kinase-3β Pathway

Murphy, L. L. S., & Hughes, C. C. W. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.7.3717 · Cited by 77 · see citing works

The proinvasive activity of Wnt‐2 is mediated through a noncanonical Wnt pathway coupled to GSK‐3β and c‐ Jun/AP‐1 signaling

Floch, N. L., Rivat, C., Wever, O. D., Bruyneel, E. A., Mareel, M., Dale, T. C., & Gespach, C. P. (2004) · The FASEB Journal · doi:10.1096/fj.04-2373fje · Cited by 74 · see citing works

Altered Expression of Genes of the Bmp/Smad and Wnt/Calcium Signaling Pathways in the Cone-only Nrl-/- Mouse Retina, Revealed by Gene Profiling Using Custom cDNA Microarrays

Yu, J., He, S., Friedman, J. S., Akimoto, M., Ghosh, D., Mears, A. J., Hicks, D., & Swaroop, A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408223200 · Cited by 58 · see citing works

Zebrafish frizzled‐2 morphant displays defects in body axis elongation

Sumanas, S., Kim, H. J., Hermanson, S., & Ekker, S. C. (2001) · genesis · doi:10.1002/gene.1043 · Cited by 45 · see citing works

Antagonist activity of DWnt-4 and wingless in the Drosophila embryonic ventral ectoderm and in heterologous Xenopus assays

Gieseler, K., Graba, Y., Mariol, M., Wilder, E. L., Martínez-Arias, A., Lemaire, P., & Pradel, J. (1999) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00097-0 · Cited by 31 · see citing works

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568 · see citing works

WNT signaling in bone homeostasis and disease: From human mutations to treatments

Baron, R., & Kneissel, M. (2013) · Nature Medicine · doi:10.1038/nm.3074 · Cited by 2,093 · see citing works

WNT signalling pathways as therapeutic targets in cancer

Anastas, J. N., & Moon, R. T. (2012) · Nature reviews. Cancer · doi:10.1038/nrc3419 · Cited by 1,902 · see citing works

Wnt signal transduction pathways

Komiya, Y., & Habas, R. (2008) · Organogenesis · doi:10.4161/org.4.2.5851 · Cited by 1,528 · see citing works

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors

Krishnamurthy, N., & Kurzrock, R. (2017) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2017.11.002 · Cited by 1,026 · see citing works

Function and biological roles of the Dickkopf family of Wnt modulators

Niehrs, C. (2006) · Oncogene · doi:10.1038/sj.onc.1210054 · Cited by 995 · see citing works

Adipogenesis: From Stem Cell to Adipocyte

Tang, Q. Q., & Lane, M. D. (2012) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-052110-115718 · Cited by 897 · see citing works

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

Gurney, A., Axelrod, F., Bond, C. J., Cain, J., Chartier, C., Donigan, L., Fischer, M., Chaudhari, A., Ji, M., Kapoun, A. M., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120068109 · Cited by 614 · see citing works

Biphasic role for Wnt/β-catenin signaling in cardiac specification in zebrafish and embryonic stem cells

Ueno, S., Weidinger, G., Osugi, T., Kohn, A. D., Golob, J. L., Pabon, L., Reinecke, H., Moon, R. T., & Murry, C. E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702859104 · Cited by 613 · see citing works

Wnt signaling: is the party in the nucleus?Preprint

Willert, K., & Jones, K. A. (2006) · Genes & Development · doi:10.1101/gad.1424006 · Cited by 591 · see citing works

β-Catenin hits chromatin: regulation of Wnt target gene activation

Mosimann, C., Hausmann, G., & Basler, K. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2654 · Cited by 577 · see citing works

Functional Anthology of Intrinsic Disorder. 1. Biological Processes and Functions of Proteins with Long Disordered Regions

Xie, H. M., Vučetić, S., Iakoucheva, L. M., Oldfield, C. J., Dunker, A. K., Uversky, V. N., & Zoran Obradovic, A. (2007) · Journal of Proteome Research · doi:10.1021/pr060392u · Cited by 556 · see citing works

Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy

Li, Q., Geng, S., Luo, H., Wang, W., Mo, Y.-Q., Luo, Q., Wang, L., Song, G.-B., Sheng, J.-P., & Xu, B. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01953-7 · Cited by 546 · see citing works

Wnt/Ca2+ signaling pathway: a brief overview

De, A. (2011) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmr079 · Cited by 532 · see citing works

Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation

Lin, G. L., & Hankenson, K. D. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23287 · Cited by 508 · see citing works

Wnt signaling: complexity at the surface

Cadigan, K. M., & Liu, Y. I. (2006) · Journal of Cell Science · doi:10.1242/jcs.02826 · Cited by 486 · see citing works

Expression of Wnt-5a Is Correlated with Aggressiveness of Gastric Cancer by Stimulating Cell Migration and Invasion

Kurayoshi, M., Oue, N., Yamamoto, H., Kishida, M., Inoue, A., Asahara, T., Yasui, W., & Kikuchi, A. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-2359 · Cited by 453 · see citing works

Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling

Hay, D. C., Fletcher, J. M., Payne, C. M., Terrace, J. D., Gallagher, R., Snoeys, J., Black, J. R., Wojtacha, D., Samuel, K., Hannoun, Z., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806522105 · Cited by 434 · see citing works

Alternative Wnt Signaling Is Initiated by Distinct Receptors

van Amerongen, R., Mikels, A. J., & Nusse, R. (2008) · Science Signaling · doi:10.1126/scisignal.135re9 · Cited by 395 · see citing works

Phospholipase D: Enzymology, Functionality, and Chemical Modulation

Selvy, P. E., Lavieri, R. R., Lindsley, C. W., & Brown, H. A. (2011) · Chemical Reviews · doi:10.1021/cr200296t · Cited by 392 · see citing works

Placental trophoblast cell differentiation: Physiological regulation and pathological relevance to preeclampsia

Ji, L., Brkić, J., Liu, M., Fu, G., Peng, C., & Wang, Y. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.12.008 · Cited by 386 · see citing works

A Wnt Survival Guide: From Flies to Human Disease

Chien, A. J., Conrad, W. H., & Moon, R. T. (2009) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.445 · Cited by 377 · see citing works

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

Movérare‐Skrtic, S., Henning, P., Liu, X., Nagano, K., Saito, H., Börjesson, A., Sjögren, K., Windahl, S. H., Farman, H. H., Kindlund, B., et al. (2014) · Nature Medicine · doi:10.1038/nm.3654 · Cited by 364 · see citing works

WNT signalling in prostate cancer

Murillo-Garzón, V., & Kypta, R. M. (2017) · Nature Reviews Urology · doi:10.1038/nrurol.2017.144 · Cited by 365 · see citing works

SnapShot: Noncanonical Wnt Signaling Pathways

Semënov, M. V., Habas, R., MacDonald, B. T., & He, X. (2007) · Cell · doi:10.1016/j.cell.2007.12.011 · Cited by 349 · see citing works

Canonical WNT signaling components in vascular development and barrier formation

Zhou, Y., Wang, Y., Tischfield, M. A., Williams, J., Smallwood, P. M., Rattner, A., Taketo, M. M., & Nathans, J. (2014) · Journal of Clinical Investigation · doi:10.1172/jci76431 · Cited by 348 · see citing works

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

Davidson, K. C., Adams, A. M., Goodson, J. M., McDonald, C. E., Potter, J. C., Berndt, J. D., Biechele, T. L., Taylor, R. J., & Moon, R. T. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1118777109 · Cited by 338 · see citing works

Wnt/β-catenin signalling: from plasma membrane to nucleus

Kim, W., Kim, M., & Jho, E. (2013) · Biochemical Journal · doi:10.1042/bj20121284 · Cited by 310 · see citing works

Wnt/β-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency

Miyabayashi, T., Teo, J.-L., Yamamoto, M., McMillan, M., Nguyen, C., & Kahn, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701331104 · Cited by 310 · see citing works

Mechanisms regulating glioma invasion

Paw, I., Carpenter, R. L., Watabe, K., Debinski, W., & Lo, H. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.03.015 · Cited by 304 · see citing works

Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling

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Wnt signaling pathways in biology and disease: mechanisms and therapeutic advances

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Gene expression profile of quiescent and activated rat hepatic stellate cells implicates Wnt signaling pathway in activation

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Wnt5a Induces Endothelial Inflammation via β-Catenin–Independent Signaling

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Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses

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Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways

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Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops

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Signaling in Cell Differentiation and MorphogenesisPreprint

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LRP5 and LRP6 in Wnt Signaling: Similarity and Divergence

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Parkinson’s disease is associated with DNA methylation levels in human blood and saliva

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Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders

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Wnt5a Induces Simultaneous Cortical Axon Outgrowth and Repulsive Axon Guidance through Distinct Signaling Mechanisms

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WNT signaling in ovarian follicle biology and tumorigenesis

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Wnt/β-Catenin Signaling in Murine Hepatic Transit Amplifying Progenitor Cells

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Targeting the WNT Signaling Pathway in Cancer Therapeutics

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Wnt5a is essential for intestinal elongation in mice

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Role of Wnt Signaling in Adult Hippocampal Neurogenesis in Health and Disease

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Regulation of NMDA-Receptor Synaptic Transmission by Wnt Signaling

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Novel therapeutic Strategies for Targeting Liver Cancer Stem Cells

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Role of the Wnt‐Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential

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Wnt-5a/Ca2+-Induced NFAT Activity Is Counteracted by Wnt-5a/Yes-Cdc42-Casein Kinase 1α Signaling in Human Mammary Epithelial Cells

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Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells

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Synaptic Wnt signaling—a contributor to major psychiatric disorders?

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Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration

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Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells

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Wnt Network: A Brief Review of Pathways and Multifunctional Components

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The Wnt/Ca2+ pathway

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Activation of Intracellular Calcium by Multiple Wnt Ligands and Translocation of β-Catenin into the Nucleus

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