Wnt Signaling in Neural Circuit Assembly

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568

The Wnt Signaling Pathway in Development and Disease

Logan, C. Y., & Nusse, R. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.113126 · Cited by 5,325

The Molecular Biology of Axon Guidance

Tessier‐Lavigne, M., & Goodman, C. S. (1996) · Science · doi:10.1126/science.274.5290.1123 · Cited by 3,311

Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors

Gordon, M. D., & Nusse, R. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.r600015200 · Cited by 1,333

Morphological Changes in Dendritic Spines Associated with Long-Term Synaptic Plasticity

Yuste, R., & Bonhoeffer, T. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1071 · Cited by 1,269

Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context

Mikels, A. J., & Nusse, R. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040115 · Cited by 1,244

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

Heisenberg, C.-P., Tada, M., Rauch, G.-J., Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C., & Wilson, S. W. (2000) · Nature · doi:10.1038/35011068 · Cited by 1,013

Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H., & Moon, R. T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00240-9 · Cited by 945

Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance

Dent, E. W., & Gertler, F. B. (2003) · Neuron · doi:10.1016/s0896-6273(03)00633-0 · Cited by 922

Wnt and calcium signaling: β-Catenin-independent pathways

Kohn, A. D., & Moon, R. T. (2005) · Cell Calcium · doi:10.1016/j.ceca.2005.06.022 · Cited by 730

Molecular Mechanisms of Axon Guidance

Dickson, B. J. (2002) · Science · doi:10.1126/science.1072165 · Cited by 721

Axonal Remodeling and Synaptic Differentiation in the Cerebellum Is Regulated by WNT-7a Signaling

Hall, A. C., Lucas, F. R., & Salinas, P. C. (2000) · Cell · doi:10.1016/s0092-8674(00)80689-3 · Cited by 699

Actin Cytoskeleton Regulation in Neuronal Morphogenesis and Structural Plasticity

Luo, L. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.031802.150501 · Cited by 658

The structure of the ventral nerve cord of Caenorhabditis elegans

White, J. G., Southgate, E., Thomson, J. N., & Brenner, S. (1976) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1976.0086 · Cited by 616

Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

Shi, S.-H., Jan, L. Y., & Jan, Y.-N. (2003) · Cell · doi:10.1016/s0092-8674(02)01249-7 · Cited by 600

Anterior-Posterior Guidance of Commissural Axons by Wnt-Frizzled Signaling

Lyuksyutova, A. I., Lu, C.-C., Milanesio, N., King, L. A., Guo, N., Wang, Y., Nathans, J., Tessier‐Lavigne, M., & Zou, Y. (2003) · Science · doi:10.1126/science.1089610 · Cited by 557

Maturation of a Central Glutamatergic Synapse

Wu, G.-Y., Malinow, R., & Cline, H. T. (1996) · Science · doi:10.1126/science.274.5289.972 · Cited by 546

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

Wallingford, J. B., & Habas, R. (2005) · Development · doi:10.1242/dev.02068 · Cited by 509

Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements

Jessen, J. R., Topczewski, J., Bingham, S., Sepich, D. S., Marlow, F., Chandrasekhar, A., & Solnica-Krezel, L. (2002) · Nature Cell Biology · doi:10.1038/ncb828 · Cited by 504

Neurotrophin Regulation of Cortical Dendritic Growth Requires Activity

McAllister, A. K., Katz, L. C., & Lo, D. C. (1996) · Neuron · doi:10.1016/s0896-6273(00)80239-1 · Cited by 503

Wnt signaling: complexity at the surface

Cadigan, K. M., & Liu, Y. I. (2006) · Journal of Cell Science · doi:10.1242/jcs.02826 · Cited by 486

Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development

Rosso, S. B., Sussman, D., Wynshaw-Boris, A., & Salinas, P. C. (2005) · Nature Neuroscience · doi:10.1038/nn1374 · Cited by 485 · cited 6×

MECHANISMS OF VERTEBRATE SYNAPTOGENESIS

Waites, C. L., Craig, A. M., & Garner, C. C. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144336 · Cited by 483

Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2

Wayman, G. A., Impey, S., Marks, D., Saneyoshi, T., Grant, W. F., Derkach, V., & Soderling, T. R. (2006) · Neuron · doi:10.1016/j.neuron.2006.05.008 · Cited by 466 · cited 4×

Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth

Lu, W., Yamamoto, V. N., Ortega, B., & Baltimore, D. (2004) · Cell · doi:10.1016/j.cell.2004.09.019 · Cited by 466

Drosophila Futsch/22C10 Is a MAP1B-like Protein Required for Dendritic and Axonal Development

Hummel, T., Krukkert, K., Roos, J., Davis, G. W., & Klämbt, C. (2000) · Neuron · doi:10.1016/s0896-6273(00)81169-1 · Cited by 464

β-catenin is critical for dendritic morphogenesis

Yu, X., & Malenka, R. C. (2003) · Nature Neuroscience · doi:10.1038/nn1132 · Cited by 459

Tissue/planar cell polarity in vertebrates: new insights and new questions

Wang, Y., & Nathans, J. (2007) · Development · doi:10.1242/dev.02772 · Cited by 442

Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases

Sin, W. C., Haas, K. Z., Ruthazer, E. S., & Cline, H. T. (2002) · Nature · doi:10.1038/nature00987 · Cited by 433

LKB1 and SAD Kinases Define a Pathway Required for the Polarization of Cortical Neurons

Barnes, A. P., Lilley, B. N., Pan, Y. A., Plummer, L. J., Powell, A. W., Raines, A. N., Sanes, J. R., & Polleux, F. (2007) · Cell · doi:10.1016/j.cell.2007.03.025 · Cited by 418

Wnt-mediated axon guidance via the Drosophila Derailed receptor

Yoshikawa, S., McKinnon, R. D., Kokel, M., & Thomas, J. B. (2003) · Nature · doi:10.1038/nature01522 · Cited by 416

The Drosophila Wnt, Wingless, Provides an Essential Signal for Pre- and Postsynaptic Differentiation

Packard, M. C., Koo, E. S., Gorczyca, M. G., Sharpe, J., Cumberledge, S., & Budnik, V. (2002) · Cell · doi:10.1016/s0092-8674(02)01047-4 · Cited by 415

Cellular and Molecular Mechanisms of Dendrite Growth

McAllister, A. K. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.963 · Cited by 382

JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins

Chang, L., Jones, Y., Ellisman, M. H., Goldstein, L. S. B., & Karin, M. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00094-7 · Cited by 375

Drosophila Futsch Regulates Synaptic Microtubule Organization and Is Necessary for Synaptic Growth

Roos, J., Hummel, T., Ng, N., Klämbt, C., & Davis, G. W. (2000) · Neuron · doi:10.1016/s0896-6273(00)81170-8 · Cited by 375

LKB1/STRAD Promotes Axon Initiation During Neuronal Polarization

Shelly, M., Cancedda, L., Heilshorn, S. C., Sumbre, G., & Poo, M. (2007) · Cell · doi:10.1016/j.cell.2007.04.012 · Cited by 368

Dynamic Aspects of CNS Synapse Formation

McAllister, A. K. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112830 · Cited by 368

Mammalian SAD Kinases Are Required for Neuronal Polarization

Kishi, M., Pan, Y. A., Crump, J. G., & Sanes, J. R. (2005) · Science · doi:10.1126/science.1107403 · Cited by 345

New Directions in Neuronal Migration

Hatten, M. E. (2002) · Science · doi:10.1126/science.1074572 · Cited by 321

Cellular and molecular mechanisms of presynaptic assembly

Ziv, N. E., & Garner, C. C. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1370 · Cited by 312

Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

Bamji, S. X., Shimazu, K., Kimes, N. E., Huelsken, J., Birchmeier, W., Lu, B., & Reichardt, L. F. (2003) · Neuron · doi:10.1016/s0896-6273(03)00718-9 · Cited by 310

Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium

Lucas, F. R., Goold, R., Gordon‐Weeks, P. R., & Salinas, P. C. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.10.1351 · Cited by 307

Mechanisms of Synapse Assembly and Disassembly

Goda, Y., & Davis, G. W. (2003) · Neuron · doi:10.1016/s0896-6273(03)00608-1 · Cited by 305

Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation

Chen, J., Park, C. S., & Tang, S.-J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511920200 · Cited by 298

How do dendrites take their shape?

Scott, E. K., & Luo, L. (2001) · Nature Neuroscience · doi:10.1038/86006 · Cited by 296

Wnt–Ryk signalling mediates medial–lateral retinotectal topographic mapping

Schmitt, A. M., Shi, J., Wolf, A. M., Lu, C.-C., King, L. A., & Zou, Y. (2006) · Nature · doi:10.1038/nature04334 · Cited by 292

Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost

Kummer, T. T., Misgeld, T., & Sanes, J. R. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.12.003 · Cited by 291

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.

Nishimura, T., Kato, K., Yamaguchi, T., Fukata, Y., Ohno, S., & Kaibuchi, K. (2004) · Nature Cell Biology · doi:10.1038/ncb1118 · Cited by 289

Glycogen synthase kinase 3β phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones

Goold, R., Owen, R., & Gordon‐Weeks, P. R. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.19.3373 · Cited by 281

WNT-7a Induces Axonal Remodeling and Increases Synapsin I Levels in Cerebellar Neurons

Lucas, F. R., & Salinas, P. C. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8734 · Cited by 280

Regulation of Cortical Dendrite Development by Slit-Robo Interactions

Whitford, K. L., Marillat, V., Stein, E., Goodman, C. S., Tessier‐Lavigne, M., Chédotal, A., & Ghosh, A. (2002) · Neuron · doi:10.1016/s0896-6273(01)00566-9 · Cited by 277

Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish

Carreira-Barbosa, F., Concha, M. L., Takeuchi, M., Ueno, N., Wilson, S. W., & Tada, M. (2003) · Development · doi:10.1242/dev.00567 · Cited by 269

The posterior nervous system of the nematode Caenorhabditis elegans: serial reconstruction of identified neurons and complete pattern of synaptic interactions

Hall, D., & Russell, R. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-01-00001.1991 · Cited by 268

Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract

Liu, Y., Shi, J., Lu, C.-C., Wang, Z.-B., Lyuksyutova, A. I., Song, X., & Zou, Y. (2005) · Nature Neuroscience · doi:10.1038/nn1520 · Cited by 264

Mechanisms that Regulate Establishment, Maintenance, and Remodeling of Dendritic Fields

Parrish, J. Z., Emoto, K., Kim, M. D., & Jan, Y. N. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112907 · Cited by 255

Control of Axon Branch Dynamics by Correlated Activity in Vivo

Ruthazer, E. S., Akerman, C. J., & Cline, H. T. (2003) · Science · doi:10.1126/science.1082545 · Cited by 247

A Wnt signaling pathway controls Hox gene expression and neuroblast migration in C. elegans

Maloof, J., Whangbo, J., Harris, J. M., Jongeward, G. D., & Kenyon, C. J. (1999) · Development · doi:10.1242/dev.126.1.37 · Cited by 245

Rho GTPases and activity-dependent dendrite development

Aelst, L. V., & Cline, H. T. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.05.012 · Cited by 239

Regulation of AChR Clustering by Dishevelled Interacting with MuSK and PAK1

Luo, Z., Wang, Q., Zhou, J., Wang, J., Luo, Z., Liu, M., He, X., Wynshaw-Boris, A. J., Xiong, W., Lu, B., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00783-3 · Cited by 238

Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release

Ahmad‐Annuar, A., Ciani, L., Simeonidis, I., Herreros, J., Fredj, N. B., Rosso, S. B., Hall, A. C., Brickley, S. G., & Salinas, P. C. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200511054 · Cited by 233

A divergent canonical WNT-signaling pathway regulates microtubule dynamics

Ciani, L., Krylova, O. Y., Smalley, M. J., Dale, T. C., & Salinas, P. C. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200309096 · Cited by 226

Microtubules and growth cone function

Gordon‐Weeks, P. R. (2003) · Journal of Neurobiology · doi:10.1002/neu.10266 · Cited by 225

Dishevelled promotes axon differentiation by regulating atypical protein kinase C

Zhang, X., Zhu, J., Yang, G.-Y., Wang, Q.-J., Qian, L., Chen, Y.-M., Chen, F., Tao, Y., Hu, H.-S., Wang, T., et al. (2007) · Nature Cell Biology · doi:10.1038/ncb1603 · Cited by 220

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans

Prasad, B. C., & Clark, S. G. (2006) · Development · doi:10.1242/dev.02357 · Cited by 219

The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein.Preprint

Sawa, H., Lobel, L. I., & Horvitz, H. R. (1996) · Genes & Development · doi:10.1101/gad.10.17.2189 · Cited by 209

WNT-3, Expressed by Motoneurons, Regulates Terminal Arborization of Neurotrophin-3-Responsive Spinal Sensory Neurons

Krylova, O. Y., Herreros, J., Cleverley, K., Ehler, E., Henríquez, J. P., Hughes, S. M., & Salinas, P. C. (2002) · Neuron · doi:10.1016/s0896-6273(02)00860-7 · Cited by 203

Postnatal maturation of cerebellar mossy and climbing fibers: transient expression of dual features on single axons

Mason, C., & Gregory, E. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-07-01715.1984 · Cited by 202

The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously

Herman, M. A., Vassilieva, L. L., Horvitz, H. R., Shaw, J. E., & Herman, R. K. (1995) · Cell · doi:10.1016/0092-8674(95)90238-4 · Cited by 199

Wnt Signals and Frizzled Activity Orient Anterior-Posterior Axon Outgrowth in C. elegans

Hilliard, M. A., & Bargmann, C. I. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.01.013 · Cited by 199

Neural map specification by gradients

Flanagan, J. G. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.01.010 · Cited by 198

Wingless Signaling at Synapses Is Through Cleavage and Nuclear Import of Receptor DFrizzled2

Mathew, D., Ataman, B., Chen, J., Zhang, Y., Cumberledge, S., & Budnik, V. (2005) · Science · doi:10.1126/science.1117051 · Cited by 186

C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling

Inoue, T., Oz, H. S., Wiland, D., Gharib, S., Deshpande, R., Hill, R. J., Katz, W. S., & Sternberg, P. W. (2004) · Cell · doi:10.1016/j.cell.2004.09.001 · Cited by 183

Differentiation of cerebellar mossy fiber synapses in the rat: A quantitative electron microscope study

Hámori, J., & Somogyi, J. (1983) · The Journal of Comparative Neurology · doi:10.1002/cne.902200402 · Cited by 181

A WNT of things to come: Evolution of Wnt signaling and polarity in cnidarians

LEE, P., PANG, K., Matus, D. Q., & Martindale, M. Q. (2006) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2006.05.002 · Cited by 180

Neuronal cell migration in C. elegans : regulation of Hox gene expression and cell position

Harris, J., Honigberg, L. A., Robinson, N., & Kenyon, C. J. (1996) · Development · doi:10.1242/dev.122.10.3117 · Cited by 173

Valproate Regulates GSK-3-Mediated Axonal Remodeling and Synapsin I Clustering in Developing Neurons

Hall, A. C., Brennan, A., Goold, R., Cleverley, K., Lucas, F. R., Gordon‐Weeks, P. R., & Salinas, P. C. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1117 · Cited by 170

A Wnt Signaling System that Specifies Two Patterns of Cell Migration in C. elegans

Whangbo, J., & Kenyon, C. J. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80394-9 · Cited by 166

On a role for competition in the formation of patterned neural connexions

Prestige, M. C., & Willshaw, D. J. (1975) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1975.0080 · Cited by 165

Multiple Wnts and Frizzled Receptors Regulate Anteriorly Directed Cell and Growth Cone Migrations in Caenorhabditis elegans

Pan, C., Howell, J. E., Clark, S. G., Hilliard, M. A., Cordes, S., Bargmann, C. I., & Garriga, G. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.02.010 · Cited by 165

Wnt Signals Can Function as Positional Cues in Establishing Cell Polarity

Goldstein, B., Takeshita, H., Mizumoto, K., & Sawa, H. (2006) · Developmental Cell · doi:10.1016/j.devcel.2005.12.016 · Cited by 163

Development and structure of synaptic contacts in Drosophila

Prokop, A., & Meinertzhagen, I. A. (2005) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2005.11.010 · Cited by 154

Building the vertebrate neuromuscular synapse

Burden, S. J. (2002) · Journal of Neurobiology · doi:10.1002/neu.10137 · Cited by 129

How actin filaments and microtubules steer growth cones to their targets

Zhou, F., & Cohan, C. S. (2003) · Journal of Neurobiology · doi:10.1002/neu.10278 · Cited by 129

Shaggy, the Homolog of Glycogen Synthase Kinase 3, Controls Neuromuscular Junction Growth inDrosophila

Franco, B., Bogdanik, L. P., Bobinnec, Y., Debec, A., Bockaert, J., Parmentier, M., & Grau, Y. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1580-04.2004 · Cited by 126

Dishevelled-1 Regulates Microtubule Stability

Krylova, O. Y., Messenger, M. J., & Salinas, P. C. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.1.83 · Cited by 124

Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP

Ataman, B., Ashley, J., Gorczyca, D., Gorczyca, M. G., Mathew, D., Wichmann, C., Sigrist, S. J., & Budnik, V. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600387103 · Cited by 123

Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain

Wada, H., Tanaka, H., Nakayama, S., Iwasaki, M., & Okamoto, H. (2006) · Development · doi:10.1242/dev.02665 · Cited by 119

Model for the retino-tectal projection

Gierer, A. (1983) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1983.0027 · Cited by 111

Regulation of acetylcholine receptor clustering by the tumor suppressor APC

Wang, J., Zheng, J., Zhang, L., Zhou, G., Braun, J., Yao, Y., & Wang, Z.-Z. (2003) · Nature Neuroscience · doi:10.1038/nn1128 · Cited by 110

Retinotectal Specificity: Models and Experiments in Search of a Mapping Function

Fraser, S. E., & Hunt, R. K. (1980) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.03.030180.001535 · Cited by 109

Wnt-7a Induces Presynaptic Colocalization of α7-Nicotinic Acetylcholine Receptors and Adenomatous Polyposis Coli in Hippocampal Neurons

Farías, G. G., Vallés, A. S., Colombres, M., Godoy, J. A., Toledo, E. M., Lukas, R. J., Barrantes, F. J., & Inestrosa, N. C. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3934-06.2007 · Cited by 108

Dishevelled: A Mobile Scaffold Catalyzing Development

Malbon, C. C., & Wang, H. (2005) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)72002-0 · Cited by 107

Competitive and positional cues in the patterning of nerve connections

Fraser, S. E., & Perkel, D. H. (1990) · Journal of Neurobiology · doi:10.1002/neu.480210105 · Cited by 104

Morphogens as conserved axon guidance cues

Zou, Y., & Lyuksyutova, A. I. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.01.006 · Cited by 102

Subcellular Localization of Frizzled Receptors, Mediated by Their Cytoplasmic Tails, Regulates Signaling Pathway Specificity

Wu, J., Klein, T. J., & Mlodzik, M. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020158 · Cited by 101

Phosphatidylinositol-3-Kinase–Atypical Protein Kinase C Signaling Is Required for Wnt Attraction and Anterior–Posterior Axon Guidance

Wolf, A. M., Lyuksyutova, A. I., Fenstermaker, A. G., Shafer, B., Lo, C. G., & Zou, Y. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0029-08.2008 · Cited by 95

The Zebrafish trilobite Gene Is Essential for Tangential Migration of Branchiomotor Neurons

Bingham, S. M., Higashijima, S., Okamoto, H., & Chandrasekhar, A. (2002) · Developmental Biology · doi:10.1006/dbio.2001.0532 · Cited by 93

DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system

Sato, M., Umetsu, D., Murakami, S., Yasugi, T., & Tabata, T. (2005) · Nature Neuroscience · doi:10.1038/nn1604 · Cited by 83

c-Jun N-terminal kinase (JNK) cooperates with Gsk3β to regulate Dishevelled-mediated microtubule stability

Ciani, L., & Salinas, P. C. (2007) · BMC Cell Biology · doi:10.1186/1471-2121-8-27 · Cited by 71

The Drosophila Wnt Protein DWnt-3 Is a Secreted Glycoprotein Localized on the Axon Tracts of the Embryonic CNS

Fradkin, L. G., Noordermeer, J. N., & Nusse, R. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1072 · Cited by 69

The C. elegans Frizzled CFZ-2 is required for cell migration and interacts with multiple Wnt signaling pathways

Zinovyeva, A., & Forrester, W. C. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.07.014 · Cited by 68

Baz, Par-6 and aPKC are not required for axon or dendrite specification in Drosophila

Rolls, M. M., & Doe, C. Q. (2004) · Nature Neuroscience · doi:10.1038/nn1346 · Cited by 67

The synaptic muscle‐specific kinase (MuSK) complex: New partners, new functions

Strochlic, L., Cartaud, A., & Cartaud, J. (2005) · BioEssays · doi:10.1002/bies.20305 · Cited by 67

Mechanisms of Dendritic Maturation

Libersat, F., & Duch, C. (2004) · Molecular Neurobiology · doi:10.1385/mn:29:3:303 · Cited by 57

Different Wnt signals act through the Frizzled and RYK receptors duringDrosophilasalivary gland migration

Harris, K. E., & Beckendorf, S. K. (2007) · Development · doi:10.1242/dev.001164 · Cited by 52

Ryk: A novel Wnt receptor regulating axon pathfinding

Keeble, T. R., & Cooper, H. M. (2006) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.07.005 · Cited by 46

Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation

Beaumont, V., Thompson, S. A., Choudhry, F., Nuthall, H. N., Glantschnig, H., Lipfert, L., David, G. R., Swain, C. J., McAllister, G., & Muñoz-Sanjuán, I. (2007) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2007.03.004 · Cited by 42

Regulation by Glycogen Synthase Kinase-3β of the Arborization Field and Maturation of Retinotectal Projection in Zebrafish

Tokuoka, H., Yoshida, T., Matsuda, N., & Mishina, M. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10324.2002 · Cited by 31

Navigating the Anterior-Posterior Axis with Wnts

Zou, Y. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.004 · Cited by 23

Acute inactivation of MAP1b in growing sympathetic neurons destabilizes axonal microtubules

Tint, I. S., Fischer, I., & Black, M. M. (2004) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20045 · Cited by 17

Two gradients are better than one

Luo, L. (2006) · Nature · doi:10.1038/439023a · Cited by 16

The Ups and Downs of Wnt Signaling

Imondi, R., & Thomas, J. B. (2003) · Science · doi:10.1126/science.1092976 · Cited by 14

Wnts send axons up and down the spinal cord

Dickson, B. J. (2005) · Nature Neuroscience · doi:10.1038/nn0905-1130 · Cited by 14

Neuroligins and neurexins link synaptic function to cognitive disease

Südhof, T. C. (2008) · Nature · doi:10.1038/nature07456 · Cited by 1,849

Microtubule assembly, organization and dynamics in axons and dendrites

Conde, C., & Cáceres, A. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2631 · Cited by 1,086

Can we safely target the WNT pathway?

Kahn, M. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4233 · Cited by 1,063

Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

Gilman, S. R., Iossifov, I., Levy, D., Ronemus, M., Wigler, M., & Vitkup, D. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.021 · Cited by 701

Mechanisms underlying development of visual maps and receptive fields

Huberman, A. D., Feller, M. B., & Chapman, B. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125533 · Cited by 628

Wnt Signaling in Vertebrate Neural Development and Function

Mulligan, K. A., & Cheyette, B. N. R. (2012) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-012-9404-x · Cited by 177

Wnt signaling: multiple functions in neural development

Ille, F., & Sommer, L. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-4552-2 · Cited by 180

WNTs in synapse formation and neuronal circuitry

Park, M., & Shen, K. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.145 · Cited by 107

Wnt Signaling in the Vertebrate Central Nervous System: From Axon Guidance to Synaptic FunctionPreprint

Salinas, P. C. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008003 · Cited by 195

Wnt Signaling in Neuromuscular Junction DevelopmentPreprint

Koles, K., & Budnik, V. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008045 · Cited by 103