The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Cancer-Associated Cachexia and Underlying Biological Mechanisms
Abstract
▪ Abstract Cancer metastases (spread to distant organs from the primary tumor site) signify systemic, progressive, and essentially incurable malignant disease. Anorexia and wasting develop continuously throughout the course of incurable cancer. Overall, in Westernized countries nearly exactly half of current cancer diagnoses end in cure and the other half end in death; thus, cancer-associated cachexia has a high prevalence. The pathophysiology of cancer-associated cachexia has two principal components: a failure of food intake and a systemic hypermetabolism/hypercatabolism syndrome. The superimposed metabolic changes result in a rate of depletion of physiological reserves of energy and protein that is greater than would be expected based on the prevailing level of food intake. These features indicate a need for nutritional support, metabolic management, and a clear appreciation of the context of life-limiting illness.
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Cites
Epidemiology of Sarcopenia among the Elderly in New Mexico
Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539
Self-citationNutritional and metabolic assessment of the hospitalized patient
Blackburn, G. L., Bistrian, B. R., Maini, B. S., Schlamm, H. T., & Smith, M. F. (1977) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/014860717700100101 · Cited by 1,426
Body Composition in Healthy Aging
BAUMGARTNER, R. N. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06498.x · Cited by 1,078
Sarcopenic Obesity Predicts Instrumental Activities of Daily Living Disability in the Elderly
Baumgartner, R. N., Wayne, S. J., Waters, D. L., Janssen, I., Gallagher, D., & Morley, J. E. (2004) · Obesity Research · doi:10.1038/oby.2004.250 · Cited by 937
What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?
Jagoe, R. T., & Goldberg, A. L. (2001) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/00075197-200105000-00003 · Cited by 399
Kelley, A. E., Baldo, B. A., & Pratt, W. E. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20769 · Cited by 352
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Skeletal Muscle Inflammation and Nitric Oxide in Patients with COPD
Montes de Oca, M., Torres, S. H., De Sanctis, J., Mata, A., Hernández, N., & Tálamo, C. (2005) · European Respiratory Journal · doi:10.1183/09031936.05.00107404 · Cited by 123
Bruera, E., Moyano, J. R., Sala, R., Rico, M. A., Bosnjak, S., Bertolino, M., Willey, J., Strasser, F., & Palmer, J. L. (2004) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2004.01.009 · Cited by 101
Cited by
Cancer cachexia: Developing multimodal therapy for a multidimensional problem
Fearon, K. C. H. (2008) · European Journal of Cancer · doi:10.1016/j.ejca.2008.02.033 · Cited by 444
Exercise, MAPK, and NF-κB signaling in skeletal muscle
Kramer, H. F., & Goodyear, L. J. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00085.2007 · Cited by 375
Dodson, S., Baracos, V. E., Jatoi, A., Evans, W. J., Cella, D., Dalton, J. T., & Steiner, M. S. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-061509-131248 · Cited by 319
Self-citationClinical implications of sarcopenic obesity in cancer
Carneiro, I. P., Mazurak, V. C., & Prado, C. M. (2016) · Current Oncology Reports · doi:10.1007/s11912-016-0546-5 · Cited by 162
Regulation of muscle atrophy in aging and disease
Vinciguerra, M., Musaro, A., & Rosenthal, N. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-7002-2_15 · Cited by 149
Metadata
- Authors
- Baracos, V. E.
- Venue
- Annual Review of Nutrition
- Publisher
- Annual Reviews
- Published
- 2006-08-01
- Volume
- 26
- Issue
- 1
- Pages
- 435-461
- ISSN
- 0199-9885 (ISSN-L)
- 1545-4312
- OpenAlex
- W2127471618
- Cited by
- 177
- References
- 10
- FWCI
- 1.18
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.