Sex-based cardiac physiology

Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial

Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889 · see citing works

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Lamb, J., Crawford, E. D., Peck, D., Modell, J. W., Blat, I. C., Wrobel, M. J., Lerner, J., Brunet, J.-P., Subramanian, A., Ross, K. N., et al. (2006) · Science · doi:10.1126/science.1132939 · Cited by 5,257 · see citing works

Therapeutic potential of resveratrol: the in vivo evidence

Baur, J. A., & Sinclair, D. A. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2060 · Cited by 3,958 · see citing works

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L.-L., et al. (2003) · Nature · doi:10.1038/nature01960 · Cited by 3,796 · see citing works

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

Levine, B., Kalman, J., Mayer, L., Fillit, H. M., & Packer, M. (1990) · New England Journal of Medicine · doi:10.1056/nejm199007263230405 · Cited by 2,582 · see citing works

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

Couse, J. F., & Korach, K. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0370 · Cited by 2,045 · see citing works

Survival after the onset of congestive heart failure in Framingham Heart Study subjects.

Ho, K. K. L., Anderson, K. M., Kannel, W. B., Grossman, W., & Levy, D. A. (1993) · Circulation · doi:10.1161/01.cir.88.1.107 · Cited by 1,865 · see citing works

Biological effects of resveratrol

Frémont, L. (2000) · Life Sciences · doi:10.1016/s0024-3205(99)00410-5 · Cited by 1,663 · see citing works

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

Geisterfer-Lowrance, A. A. T., Kass, S., Tanigawa, G., Vosberg, H.-P., McKenna, W., Seidman, C. E., & Seidman, J. G. (1990) · Cell · doi:10.1016/0092-8674(90)90274-i · Cited by 1,380 · see citing works

Sex-Based Differences in Early Mortality after Myocardial Infarction

Vaccarino, V., Parsons, L. S., Every, N. R., Barron, H. V., & Krumholz, H. M. (1999) · New England Journal of Medicine · doi:10.1056/nejm199907223410401 · Cited by 1,297 · see citing works

Postmenopausal Estrogen and Progestin Use and the Risk of Cardiovascular Disease

Grodstein, F., Stampfer, M. J., Manson, J. E., Colditz, G. A., Willett, W. C., ROSNER, B. A., Speizer, F. E., & Hennekens, C. H. (1996) · New England Journal of Medicine · doi:10.1056/nejm199608153350701 · Cited by 1,294 · see citing works

The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones

Setchell, K. D. R., Brown, N. M., & Lydeking-Olsen, E. (2002) · The Journal of Nutrition · doi:10.1093/jn/132.12.3577 · Cited by 1,209 · see citing works

Determinants of disease and disability in the elderly: The Rotterdam elderly study

Albert Hofman, D., Grobbee, D. E., de Jong, P. T. V. M., & Ouweland, F. A. V. D. (1991) · European Journal of Epidemiology · doi:10.1007/bf00145007 · Cited by 1,129 · see citing works

Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart

Torre‐Amione, G., Kapadia, S. R., Lee, J. J., Durand, J., Bies, R. D., Young, J. B., & Mann, D. L. (1996) · Circulation · doi:10.1161/01.cir.93.4.704 · Cited by 991 · see citing works

Seven-transmembrane-spanning receptors and heart function

Rockman, H. A., Koch, W. J., & Lefkowitz, R. J. (2002) · Nature · doi:10.1038/415206a · Cited by 938 · see citing works

Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the <i>cyp19</i> gene

Fisher, C. R., Graves, K. H., Parlow, A. F., & Simpson, E. R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.12.6965 · Cited by 867 · see citing works

Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α

Kubota, T., McTiernan, C. F., Frye, C. S., Slawson, S. E., Lemster, B. H., Koretsky, A. P., Demetris, A. J., & Feldman, A. M. (1997) · Circulation Research · doi:10.1161/01.res.81.4.627 · Cited by 828 · see citing works

Prevalence and mortality rate of congestive heart failure in the United States

Schocken, D. D., Arrieta, M. I., Leaverton, P. E., & Ross, E. A. (1992) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(92)90094-4 · Cited by 809 · see citing works

Resveratrol Prolongs Lifespan and Retards the Onset of Age-Related Markers in a Short-Lived Vertebrate

Valenzano, D. R., Tozzini, E. T., Genade, T., Cattaneo, A., Domenici, L., & Cellerino, A. (2006) · Current Biology · doi:10.1016/j.cub.2005.12.038 · Cited by 786 · see citing works

Plasma concentrations of phyto-oestrogens in Japanese men.

Adlercreutz, H., Markkanen, H., & Watanabe, S. (1993) · The Lancet · doi:10.1016/0140-6736(93)92188-y · Cited by 754 · see citing works

Exposure of infants to phyto-oestrogens from soy-based infant formula

Setchell, K. D. R., Zimmer-Nechemias, L., Cai, J., & Heubi, J. E. (1997) · The Lancet · doi:10.1016/s0140-6736(96)09480-9 · Cited by 704 · see citing works

Soy Protein, Isoflavones, and Cardiovascular Health: An American Heart Association Science Advisory for Professionals From the Nutrition Committee

Sacks, F. M., Lichtenstein, A., Van Horn, L., Harris, W., Kris-Etherton, P., & Winston, M. (2006) · Circulation · doi:10.1161/circulationaha.106.171052 · Cited by 656 · see citing works

Gender differences and aging: Effects on the human heart

Olivetti, G., Giordano, G., Corradi, D., Melissari, M., Lagrasta, C. A. M., Gambert, S. R., & Anversa, P. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00282-8 · Cited by 574 · see citing works

Bioavailability of Soybean Isoflavones Depends upon Gut Microflora in Women

Xu, X., Harris, K. S., Wang, H., Murphy, P. A., & Hendrich, S. (1995) · Journal of Nutrition · doi:10.1093/jn/125.9.2307 · Cited by 548 · see citing works

Tumor Necrosis Factor Soluble Receptors in Patients With Various Degrees of Congestive Heart Failure

Ferrari, R., Bachetti, T., Confortini, R., Opasich, C., Febo, O., Corti, A., Cassani, G., & Visioli, O. (1995) · Circulation · doi:10.1161/01.cir.92.6.1479 · Cited by 535 · see citing works

The Exclusion of the Elderly and Women From Clinical Trials in Acute Myocardial Infarction

Gurwitz, J. H. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03490110055029 · Cited by 532 · see citing works

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

Couse, J. F. (1999) · Endocrine Reviews · doi:10.1210/er.20.3.358 · Cited by 532 · see citing works

Resveratrol Acts as a Mixed Agonist/Antagonist for Estrogen Receptors α and β*

Bowers, J. L., Tyulmenkov, V. V., Jernigan, S. C., & Klinge, C. M. (2000) · Endocrinology · doi:10.1210/endo.141.10.7721 · Cited by 527 · see citing works

Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo

Antos, C. L., McKinsey, T. A., Frey, N., Kutschke, W. J., McAnally, J., Shelton, J. M., Richardson, J. A., Hill, J. A., & Olson, E. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231619298 · Cited by 477 · see citing works

Phenotypic Spectrum Caused by Transgenic Overexpression of Activated Akt in the Heart

Matsui, T., Li, L., Wu, J. C., Cook, S. A., Nagoshi, T., Picard, M. H., Liao, R., & Rosenzweig, A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200347200 · Cited by 434 · see citing works

Androgen Receptors Mediate Hypertrophy in Cardiac Myocytes

Marsh, J. D., Lehmann, M. H., Ritchie, R. H., Gwathmey, J. K., Green, G. E., & SCHIEBINGER, R. J. (1998) · Circulation · doi:10.1161/01.cir.98.3.256 · Cited by 433 · see citing works

Pharmacokinetics of Soybean Isoflavones in Plasma, Urine and Feces of Men after Ingestion of 60 g Baked Soybean Powder (Kinako)

Watanabe, S., Yamaguchi, M., Sobue, T., Takahashi, T., Miura, T., Arai, Y., Mazur, W., Wähälä, K., & Adlercreutz, H. (1998) · Journal of Nutrition · doi:10.1093/jn/128.10.1710 · Cited by 423 · see citing works

Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans

King, R. A., & Bursill, D. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/67.5.867 · Cited by 412 · see citing works

A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice.

Djouadi, F., Weinheimer, C. J., Saffitz, J. E., Pitchford, C., Bastin, J., Gonzalez, F. J., & Kelly, D. P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3949 · Cited by 410 · see citing works

Detection of the effects of phytoestrogens on sheep and cattle

Adams, N. R. (1995) · Journal of Animal Science · doi:10.2527/1995.7351509x · Cited by 358 · see citing works

Dietary estrogens—A probable cause of infertility and liver disease in captive cheetahs

Setchell, K. D. R., Gosselin, S. J., Welsh, M. B., Johnston, J. O., Balistreri, W. F., Kramer, L., Dresser, B. L., & Tarr, M. J. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)91006-7 · Cited by 353 · see citing works

The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury

Ray, P. S., Maulik, G., Cordis, G. A., Bertelli, A. A. E., Bertelli, A., & Das, D. K. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00063-5 · Cited by 342 · see citing works

The cardiac toxicity of anabolic steroids

Sullivan, M. L., Martinez, C., Gennis, P., & Gallagher, E. J. (1998) · Progress in Cardiovascular Diseases · doi:10.1016/s0033-0620(98)80019-4 · Cited by 337 · see citing works

17β-Estradiol Reduces Cardiomyocyte Apoptosis In Vivo and In Vitro via Activation of Phospho-Inositide-3 Kinase/Akt Signaling

Patten, R. D., Pourati, I., Aronovitz, M. J., Baur, J., Celestin, F., Chen, X., Michael, A., Haq, S., Nuedling, S., Grohé, C., et al. (2004) · Circulation Research · doi:10.1161/01.res.0000144126.57786.89 · Cited by 333 · see citing works

Development and proliferative capacity of cardiac muscle cells.

Zak, R. (1974) · PubMed · Cited by 320 · see citing works

17β-Estradiol Attenuates the Development of Pressure-Overload Hypertrophy

van Eickels, M., Grohé, C., Cleutjens, J. P. M., Janssen, B. J., Wellens, H. J. J., & Doevendans, P. A. (2001) · Circulation · doi:10.1161/hc3601.095577 · Cited by 300 · see citing works

Animal Models Impacted by Phytoestrogens in Commercial Chow: Implications for Pathways Influenced by Hormones

Brown, N. M., & Setchell, K. D. R. (2001) · Laboratory Investigation · doi:10.1038/labinvest.3780282 · Cited by 297 · see citing works

Invited Review: Cell localization, physiology, and nongenomic actions of estrogen receptors

Levin, E. R. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.4.1860 · Cited by 293 · see citing works

LESSONS IN ESTROGEN BIOLOGY FROM KNOCKOUT AND TRANSGENIC ANIMALS

Hewitt, S. C., Harrell, J. C., & Korach, K. S. (2004) · Annual Review of Physiology · doi:10.1146/annurev.physiol.67.040403.115914 · Cited by 292 · see citing works

Association of Dietary Intake of Soy, Beans, and Isoflavones With Risk of Cerebral and Myocardial Infarctions in Japanese Populations

Kokubo, Y., Iso, H., Ishihara, J., Okada, K., Inoue, M., & Tsugane, S. (2007) · Circulation · doi:10.1161/circulationaha.106.683755 · Cited by 283 · see citing works

Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload

Douglas, P. S., Katz, S. E., Weinberg, E. O., Chen, M. H., Bishop, S. P., & Lorell, B. H. (1998) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00347-7 · Cited by 282 · see citing works

Myocardial Akt Activation and Gender

Camper-Kirby, D., Welch, S., Walker, A., Shiraishi, I., Setchell, K. D. R., SCHAEFER, E. M., Kajstura, J., Anversa, P., & Sussman, M. A. (2001) · Circulation Research · doi:10.1161/hh1001.090858 · Cited by 267 · see citing works

Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): a randomised controlled trial of hormone replacement therapy in postmenopausal women

Vickers, M. R., MacLennan, A. H., LAWTON, B. A., Ford, D., Martin, J., Meredith, S. K., Stavola, B. L. D., Rose, S. B., Dowell, A. C., Wilkes, H. C., et al. (2007) · BMJ · doi:10.1136/bmj.39266.425069.ad · Cited by 255 · see citing works

Effect of 17β‐oestradiol on contraction, Ca2+ current and intracellular free Ca2+ in guinea‐pig isolated cardiac myocytes

Jiang, C., Poole-Wilson, P. A., Sarrel, P. M., Mochizuki, S., Collins, P. D., & MacLeod, K. T. (1992) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1992.tb14403.x · Cited by 247 · see citing works

Gender Differences in Left Ventricular Growth

SIMONE, G. D., Devereux, R. B., Daniels, S. R., & Meyer, R. A. (1995) · Hypertension · doi:10.1161/01.hyp.26.6.979 · Cited by 245 · see citing works

The phytoestrogen genistein induces thymic and immune changes: A human health concern?

Yellayi, S., Naaz, A., Szewczykowski, M. A., Sato, T., Woods, J. A., Chang, J., Segre, M., Allred, C. D., Helferich, W. G., & Cooke, P. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.102650199 · Cited by 244 · see citing works

Estrogens Increase Transcription of the Human Endothelial NO Synthase Gene

Kleinert, H., Wallerath, T., Euchenhofer, C., Ihrig‐Biedert, I., Li, H., & Förstermann, U. (1998) · Hypertension · doi:10.1161/01.hyp.31.2.582 · Cited by 239 · see citing works

Phytoestrogen content of purified, open- and closed-formula laboratory animal diets.

Thigpen, J. E., Setchell, K. D. R., Ahlmark, K. B., Locklear, J., Spahr, T., Caviness, G. F., Goelz, M. F., Haseman, J. K., Newbold, R. R., & Forsythe, D. B. (1999) · PubMed · Cited by 237 · see citing works

Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy

Tardiff, J. C., Hewett, T. E., Palmer, B. M., Olsson, M. C., Factor, S. M., Moore, R. L., Robbins, J. M., & Leinwand, L. A. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6067 · Cited by 230 · see citing works

Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury

Gabel, S. A., WALKER, V., London, R. E., Steenbergen, C., Korach, K. S., & Murphy, E. (2005) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2004.11.013 · Cited by 222 · see citing works

Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice

Cavasin, M. A., Tao, Z., Menon, S., & Yang, X. (2004) · Life Sciences · doi:10.1016/j.lfs.2004.04.024 · Cited by 221 · see citing works

Estrogen receptor-β mediates male-female differences in the development of pressure overload hypertrophy

Skavdahl, M., Steenbergen, C., Clark, J. A., Myers, P., Demianenko, T. K., Mao, L., Rockman, H. A., Korach, K. S., & Murphy, E. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00723.2004 · Cited by 216 · see citing works

Nuclear Targeting of Akt Enhances Kinase Activity and Survival of Cardiomyocytes

Shiraishi, I., Melendez, J., Ahn, Y., Skavdahl, M., Murphy, E., Welch, S., Schaefer, E., Walsh, K., Rosenzweig, A., Torella, D., et al. (2004) · Circulation Research · doi:10.1161/01.res.0000124394.01180.be · Cited by 212 · see citing works

The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

O’Connell, T. D., Ishizaka, S., Nakamura, A., Swigart, P. M., Rodrigo, M. C., Simpson, G. L., Cotecchia, S., Rokosh, G. D., Grossman, W., Foster, E., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16100 · Cited by 205 · see citing works

Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction

Cavasin, M. A., Sankey, S. S., Yu, A.-L., Menon, S., & Yang, X.-P. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01087.2002 · Cited by 204 · see citing works

Sex modifies exercise and cardiac adaptation in mice

Konhilas, J. P., Maass, A. H., Luckey, S. W., Stauffer, B. L., Olson, E. N., & Leinwand, L. A. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00292.2004 · Cited by 203 · see citing works

Phytoestrogens: Adverse Effects on Reproduction in California Quail

Leopold, A. S., Erwin, M., Oh, J. S., & Browning, B. M. (1976) · Science · doi:10.1126/science.1246602 · Cited by 200 · see citing works

A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy.

Tardiff, J. C., Factor, S. M., Tompkins, B., Hewett, T. E., Palmer, B. M., Moore, R. L., Schwartz, S. D., Robbins, J. M., & Leinwand, L. A. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2389 · Cited by 193 · see citing works

Genistein Affects Adipose Tissue Deposition in a Dose-Dependent and Gender-Specific Manner

Penza, M., Montani, C., Romani, A., Vignolini, P., Pampaloni, B., Tanini, A., Brandi, M. L., Alonso‐Magdalena, P., Nadal, Á., Ottobrini, L., et al. (2006) · Endocrinology · doi:10.1210/en.2006-0365 · Cited by 193 · see citing works

17β-Estradiol stimulates expression of endothelial and inducible NO synthase in rat myocardium in-vitro and in-vivo

Nuedling, S. (1999) · Cardiovascular Research · doi:10.1016/s0008-6363(99)00093-0 · Cited by 191 · see citing works

Increased Expression of the Cardiac L-type Calcium Channel in Estrogen Receptor–deficient Mice

Johnson, B. D., Zheng, W., Korach, K. S., Scheuer, T., Catterall, W. A., & Rubanyi, G. M. (1997) · The Journal of General Physiology · doi:10.1085/jgp.110.2.135 · Cited by 188 · see citing works

Adverse Effects on Female Development and Reproduction in CD-1 Mice Following Neonatal Exposure to the Phytoestrogen Genistein at Environmentally Relevant Doses

Jefferson, W. N., Padilla‐Banks, E., & Newbold, R. R. (2005) · Biology of Reproduction · doi:10.1095/biolreprod.105.041277 · Cited by 183 · see citing works

The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

O’Connell, T. D., Ishizaka, S., Nakamura, A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200316100 · Cited by 169 · see citing works

The effects of gonadectomy on left ventricular function and cardiac contractile proteins in male and female rats.

Schaible, T., Malhotra, A., Ciambrone, G., & Scheuer, J. (1984) · Circulation Research · doi:10.1161/01.res.54.1.38 · Cited by 166 · see citing works

Mice Expressing Mutant Myosin Heavy Chains Are a Model for Familial Hypertrophic Cardiomyopathy

Vikstrom, K. L., Factor, S. M., & Leinwand, L. A. (1996) · Molecular Medicine · doi:10.1007/bf03401640 · Cited by 165 · see citing works

Effect of soy isoflavone supplementation on markers of oxidative stress in men and women

Djurić, Z., Chen, G., Doerge, D. R., Heilbrun, L. K., & Kucuk, O. (2001) · Cancer Letters · doi:10.1016/s0304-3835(01)00627-9 · Cited by 160 · see citing works

Gender-related differences in left ventricular chamber function

Hayward, C. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(00)00280-7 · Cited by 157 · see citing works

Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender-specific phenotype

Du, X. (2003) · Cardiovascular Research · doi:10.1016/s0008-6363(02)00663-6 · Cited by 156 · see citing works

Sex-related differences in the normal cardiac response to upright exercise.

Higginbotham, M. B., Morris, K. G., Coleman, R. E., & Cobb, F. R. (1984) · Circulation · doi:10.1161/01.cir.70.3.357 · Cited by 155 · see citing works

Estrogen receptor alpha up‐regulation and redistribution in human heart failure

Mahmoodzadeh, S., Eder, S., Nordmeyer, J., Ehler, E., Huber, O., Martus, P., Weiske, J., Pregla, R., Hetzer, R., & Regitz‐Zagrosek, V. (2006) · The FASEB Journal · doi:10.1096/fj.05-5148com · Cited by 150 · see citing works

Myocardial ischemia-reperfusion injury in estrogen receptor-α knockout and wild-type mice

Zhai, P., Eurell, T. E., Cooke, P. S., Lubahn, D. B., & Gross, D. R. (2000) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2000.278.5.h1640 · Cited by 141 · see citing works

Human Relaxins: Chemistry and Biology*

Bryant‐Greenwood, G. D., & Schwabe, C. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-1-5 · Cited by 138 · see citing works

Sex-related survival differences in murine cardiomyopathy are associated with differences in TNF-receptor expression

Kadokami, T., McTiernan, C. F., Kubota, T., Frye, C. S., & Feldman, A. M. (2000) · Journal of Clinical Investigation · doi:10.1172/jci9307 · Cited by 136 · see citing works

Endocrine activity of the postmenopausal ovary: the effects of pituitary down-regulation and oophorectomy

Sluijmer, A. V., Heineman, M. J., de Jong, F. H., & Evers, J. L. H. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.7.7608272 · Cited by 134 · see citing works

Upregulation of Myocardial Estrogen Receptors in Human Aortic Stenosis

Nordmeyer, J., Eder, S., Mahmoodzadeh, S., Martus, P., Fielitz, J., Bass, J. K., Bethke, N., Zurbrügg, H. R., Pregla, R., Hetzer, R., et al. (2004) · Circulation · doi:10.1161/01.cir.0000147610.41984.e8 · Cited by 131 · see citing works

Coordinated induction of iNOS–VEGF–KDR–eNOS after resveratrol consumption

Das, S., Alagappan, V. K. T., Bagchi, D., SHARMA, H. S., Maulik, N., & Das, D. K. (2005) · Vascular Pharmacology · doi:10.1016/j.vph.2005.02.013 · Cited by 129 · see citing works

Basic & Clinical Endocrinology

Greenspan, F. S., & Strewler, G. J. (1990) · Medical Entomology and Zoology · Cited by 127 · see citing works

Superinhibition of Sarcoplasmic Reticulum Function by Phospholamban Induces Cardiac Contractile Failure

Haghighi, K., Schmidt, A. G., Hoit, B. D., Brittsan, A. G., Yatani, A., Lester, J. W., Zhai, J., Kimura, Y., Dorn, G. W., MacLennan, D. H., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102403200 · Cited by 127 · see citing works

Gender-Related Differences in Myocyte Remodeling in Progression to Heart Failure

Tamura, T., Said, S., & Gerdes, A. M. (1999) · Hypertension · doi:10.1161/01.hyp.33.2.676 · Cited by 126 · see citing works

Increased Mortality and Aggravation of Heart Failure in Estrogen Receptor-β Knockout Mice After Myocardial Infarction

Pelzer, T., Arias-Loza, P.-A., Hu, K., Bayer, B., Dienesch, C., Calvillo, L., Couse, J. F., Korach, K. S., Neyses, L., & Ertl, G. (2005) · Circulation · doi:10.1161/01.cir.0000159262.18512.46 · Cited by 126 · see citing works

Cardiac effects of relaxin in rats

Kakouris, H., EDDIE, L. W., & Summers, R. J. (1992) · The Lancet · doi:10.1016/0140-6736(92)90665-p · Cited by 122 · see citing works

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Testosterone enhances estradiol's cardioprotection in ovariectomized rats

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Sex Differences in Morphological and Functional Aspects of Exercise-Induced Cardiac Hypertrophy in a Rat Model

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Gender-dependent effects of high-fat lard diet on cardiac function in C57Bl/6J mice

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The impact of ovariectomy on cardiac excitation-contraction coupling is mediated through cAMP/PKA-dependent mechanisms

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Estrogen but not testosterone preserves myofilament function from doxorubicin-induced cardiotoxicity by reducing oxidative modifications

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A machine learning strategy for fast prediction of cardiac function based on peripheral pulse wave

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Sex-specific cardiovascular responses to control or high fat diet feeding in C57bl/6 mice chronically exposed to bisphenol A.

Patel, B. B., Raad, M., Sebag, I. A., & Chalifour, L. E. (2015) · Toxicology Reports · doi:10.1016/j.toxrep.2015.09.008 · Cited by 27 · see citing works

Androgen Effects on the Adrenergic System of the Vascular, Airway, and Cardiac Myocytes and Their Relevance in Pathological Processes

Carbajal-García, A., Reyes-García, J., & Montaño, L. M. (2020) · International Journal of Endocrinology · doi:10.1155/2020/8849641 · Cited by 27 · see citing works

Effects of biological sex on the pathophysiology of the heart

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Differential patterns of effects of age and sex on metabolic syndrome in Taiwan: Implication for the inadequate internal consistency of the current criteria

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Sex-chromosome mechanisms in cardiac development and disease

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Diabetes Mellitus Impairs Left Ventricular Mass Regression after Surgical or Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis

Nakamura, T., Toda, K., Kuratani, T., Miyagawa, S., Yoshikawa, Y., Fukushima, S., Saito, S., Yoshioka, D., Kashiyama, N., Daimon, T., et al. (2015) · Heart Lung and Circulation · doi:10.1016/j.hlc.2015.05.019 · Cited by 25 · see citing works

Sex-Specific Impacts of Exercise on Cardiovascular Remodeling

Islam, R. A., Khalsa, S. S. S., Vyas, A. K., & Rahimian, R. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10173833 · Cited by 24 · see citing works

Regulation of large conductance calcium- and voltage-activated potassium (BK) channels by S-palmitoylation

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Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers

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Kidney Ischemia-Reperfusion Decreases Hydrogen Sulfide and Increases Oxidative Stress in the Heart

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Cardiac ischaemic stress: Cardiomyocyte Ca2+, sex and sex steroids

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Predictors of Cardiovascular Risk in Women

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Autonomic and cardiovascular consequences resulting from experimental hemorrhagic stroke in the left or right intermediate insular cortex in rats

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Studies of Twin Responses to Understand Exercise Therapy (STRUETH): body composition

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The female human heart at rest and during exercise: A review

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Association between reduced myocardial contraction fraction and cardiovascular disease outcomes: The Multi-Ethnic Study of Atherosclerosis

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Atrioventricular mechanical coupling and major adverse cardiac events in female patients following acute ST elevation myocardial infarction

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Clinical and pathological findings in rabbits with cardiovascular disease: 59 cases (2001–2018)

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Age-related differences in left ventricular structure and function between healthy men and women

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Suppressed G ‐protein‐coupled receptor kinase 2 activity protects female diabetic‐mouse aorta against endothelial dysfunction

Taguchi, K., Matsumoto, T., Kamata, K., & Kobayashi, T. (2012) · Acta Physiologica · doi:10.1111/j.1748-1716.2012.02473.x · Cited by 17 · see citing works

RhoA/ROCK signaling contributes to sex differences in the activation of human platelets

Schubert, P., Coupland, D., Nombalais, M., Walsh, G. M., & Devine, D. V. (2016) · Thrombosis Research · doi:10.1016/j.thromres.2016.01.007 · Cited by 17 · see citing works

Inter-Individual Variation and Cardioprotection in Anthracycline-Induced Heart Failure

Norton, N., Weil, R. M., & Advani, P. P. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10184079 · Cited by 16 · see citing works

Cardiac structure/function, protein expression, and DNA methylation are changed in adult female mice exposed to diethylstilbestrol in utero

Haddad, R., Kasneci, A., Sebag, I. A., & Chalifour, L. E. (2013) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2013-0014 · Cited by 16 · see citing works

Gender-specific implications for pharmacology in childbearing age and in postmenopausal women

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Estrogen receptor antagonism exacerbates cardiac structural and functional remodeling in female rats

Hajj, M. C. E., Ninh, V. K., Hajj, E. C. E., Bradley, J., & Gardner, J. D. (2016) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00348.2016 · Cited by 16 · see citing works

Distribution of cardiac troponin I in the Japanese general population and factors influencing its concentrations

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Natriuretic peptide system: A link between fat mass and cardiac hypertrophy and hypertension in fat-fed female rats

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Sexual dimorphism in cardiac transcriptome associated with a troponin C murine model of hypertrophic cardiomyopathy

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Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis

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What We Know and Do Not Know about Sex and Cardiac Disease

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mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats

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X-Chromosome–Linked miRNAs Regulate Sex Differences in Cardiac Physiology

Emerson, J. I., Shi, W., Paredes-Larios, J., Walker, W. G., Hutton, J. E., Cristea, I. M., Marzluff, W. F., & Conlon, F. L. (2024) · Circulation Research · doi:10.1161/circresaha.124.325447 · Cited by 14 · see citing works

Boosted classification trees result in minor to modest improvement in the accuracy in classifying cardiovascular outcomes compared to conventional classification trees.

Austin, P. C., & Lee, D. S. (2011) · Europe PMC (PubMed Central) · Cited by 14 · see citing works

Irreversible perinatal imprinting of adult expression of the principal sex‐dependent drug‐metabolizing enzyme CYP2C11

Das, R. K., Banerjee, S., & Shapiro, B. H. (2014) · The FASEB Journal · doi:10.1096/fj.13-248864 · Cited by 13 · see citing works

Novel Effects of Chromosome Y on Cardiac Regulation, Chromatin Remodeling, and Neonatal Programming in Male Mice

Praktiknjo, S. D., Llamas, B., Scott‐Boyer, M., Picard, S., Robert, F., Langlais, D., Haibe‐Kains, B., Faubert, D., Silversides, D. W., & Deschepper, C. F. (2013) · Endocrinology · doi:10.1210/en.2013-1699 · Cited by 13 · see citing works

Effects of intermittent pneumatic compression on the recovery of cardiovascular parameters after repeated sprint exercise

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Sex-dependent pathophysiological mechanisms in hypertrophic cardiomyopathy: Implications for rhythm disorders

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Investigation of sex-based differences in the immunotoxicity of silver nanoparticles

Canup, B. S. B., Rogers, P., Paredes, A. M., Manheng, W., Lyn‐Cook, B. D., & Fahmi, T. (2024) · Nanotoxicology · doi:10.1080/17435390.2024.2323070 · Cited by 11 · see citing works

Dydrogesterone does not reverse the cardiovascular benefits of percutaneous estradiol

Kuba, V. M., Teixeira, M. A., Meirelles, R. M. R., de Assumpção, C. R. L., & Costa, O. S. (2012) · Climacteric · doi:10.3109/13697137.2012.672843 · Cited by 11 · see citing works

Age- and Body Size-Adjusted Left Ventricular End-Diastolic Dimension in a Japanese Hospital-Based Population

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Association of free androgen index and sex hormone–binding globulin and left ventricular hypertrophy in postmenopausal hypertensive women

Jianshu, C., Qiongying, W., Ying, P., Ningyin, L., Han, J., & Jing, Y. (2021) · Journal of Clinical Hypertension · doi:10.1111/jch.14301 · Cited by 11 · see citing works

Sex and Response to Cardioprotective Conditioning Maneuvers

Querio, G., Geddo, F., Antoniotti, S., Gallo, M. P., & Penna, C. R. R. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.667961 · Cited by 10 · see citing works

Cohort of estrogen-induced microRNAs regulate adrenomedullin expression

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Pregnancy mitigates cardiac pathology in a mouse model of left ventricular pressure overload

Xu, H., van Deel, E. D., Johnson, M. R., Opić, P., Herbert, B. R., Moltzer, E., Sooranna, S. R., van Beusekom, H. M. M., Zang, W., Duncker, D. J., et al. (2016) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00056.2016 · Cited by 10 · see citing works

Anti-androgenic therapy with finasteride in patients with chronic heart failure - a retrospective propensity score based analysis

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Cardiovascular multimodality imaging in women: a scientific statement of the European Association of Cardiovascular Imaging of the European Society of Cardiology

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Differences in Androgen Receptor Expression in Human Heart Tissue in Various Types of Cardiomyopathy and in Aortic Valve Stenosis

Eildermann, K., Goldmann, S., Krause, U., Backhoff, D., Schöndube, F. A., Paul, T., Quentin, T., & Müller, M. J. (2023) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd10110466 · Cited by 9 · see citing works

Roxadustat reduces left ventricular mass index compared to rHuEPO in haemodialysis patients in a randomized controlled trial

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RSK3 is required for concentric myocyte hypertrophy in an activated Raf1 model for Noonan syndrome

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Relapsing polychondritis: focus on cardiac involvement

Yin, R., Zhao, M., Xu, D., Wang, Q., Li, M., Zhang, W., Zhang, F., Zeng, X., Huo, Y., & Hou, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1218475 · Cited by 9 · see citing works

Comparisons of chromosome Y-substituted mouse strains reveal that the male-specific chromosome modulates the effects of androgens on cardiac functions

Praktiknjo, S. D., Picard, S., & Deschepper, C. F. (2016) · Biology of Sex Differences · doi:10.1186/s13293-016-0116-4 · Cited by 8 · see citing works

Cardioprotective potential of indol-3-carbinol against high salt induced myocardial stress and hypertrophy in Sprague dawley rats besides molecular docking on muscarinic receptor-2

Sudheer, A., Kanala, S. R., Khatri, S., Kutagulla, V. K., Mallela, V., & Peraman, R. (2021) · Natural Product Research · doi:10.1080/14786419.2021.1912042 · Cited by 8 · see citing works

Unveiling Catecholamine Dynamics in Cardiac Health and Disease: Mechanisms, Implications, and Future Perspectives

Xiang, W., Wang, X., Li, L., Zeng, J., Lu, H., & Wang, Y. (2023) · International Journal of Drug Discovery and Pharmacology · doi:10.53941/ijddp.2023.100012 · Cited by 7 · see citing works

Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review

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Sex and sex hormones in cardiac stress—Mechanistic insights

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The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease

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Sex is a potent modifier of the cardiovascular system

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Sex differences in myocardial metabolism and cardiac function: an emerging concept

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