PKC-δ-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase

Biochemistry and molecular cell biology of diabetic complications

Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107 · see citing works

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760 · see citing works

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Nishikawa, T., Edelstein, D., Du, X. L., Yamagishi, S.-I., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H.-P., et al. (2000) · Nature · doi:10.1038/35008121 · Cited by 4,277 · see citing works

Role of Oxidative Stress in Development of Complications in Diabetes

Baynes, J. (1991) · Diabetes · doi:10.2337/diab.40.4.405 · Cited by 3,791 · see citing works

Obesity and insulin resistance

Kahn, B. B., & Flier, J. S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10842 · Cited by 3,283 · see citing works

Specificity and mechanism of action of some commonly used protein kinase inhibitors.

Davies, S., Reddy, H., Caivano, M., & Cohen, P. (2000) · Biochemical Journal · doi:10.1042/bj3510095 · Cited by 3,164 · see citing works

Protein kinase C and lipid signaling for sustained cellular responses

Nishizuka, Y. (1995) · The FASEB Journal · doi:10.1096/fasebj.9.7.7737456 · Cited by 2,499 · see citing works

Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes

Evans, J. L., Goldfine, I. D., Maddux, B. A., & Grodsky, G. M. (2002) · Endocrine Reviews · doi:10.1210/er.2001-0039 · Cited by 2,232 · see citing works

NADPH Oxidase: An Update

BABIOR, B. M. (1999) · Blood · doi:10.1182/blood.v93.5.1464 · Cited by 2,147 · see citing works

Specificity and mechanism of action of some commonly used protein kinase inhibitors

Davies, S., Reddy, H., Caivano, M., & Cohen, P. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3510095 · Cited by 1,618 · see citing works

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

Inoguchi, T., Li, P., Umeda, F., Yu, H. Y., Kakimoto, M., Imamura, M., Aoki, T., Etoh, T., Hashimoto, T., Naruse, M., et al. (2000) · Diabetes · doi:10.2337/diabetes.49.11.1939 · Cited by 1,577 · see citing works

The extended protein kinase C superfamily

MELLOR, H., & Parker, P. J. (1998) · Biochemical Journal · doi:10.1042/bj3320281 · Cited by 1,539 · see citing works

Protein kinase C activation and the development of diabetic complications.

Koya, D., & King, G. L. (1998) · Diabetes · doi:10.2337/diabetes.47.6.859 · Cited by 1,316 · see citing works

Adipogenesis and Obesity: Rounding Out the Big Picture

Spiegelman, B. M., & Flier, J. S. (1996) · Cell · doi:10.1016/s0092-8674(00)81359-8 · Cited by 1,254 · see citing works

Diet-Induced Type II Diabetes in C57BL/6J Mice

Surwit, R. S., Kuhn, C. M., Cochrane, C., McCubbin, J. A., & Feinglos, M. N. (1988) · Diabetes · doi:10.2337/diab.37.9.1163 · Cited by 1,211 · see citing works

Radicals and oxidative stress in diabetes

West, I. C. (2000) · Diabetic Medicine · doi:10.1046/j.1464-5491.2000.00259.x · Cited by 913 · see citing works

Rottlerin, a Novel Protein Kinase Inhibitor

Gschwendt, M., Müller, H.-J., Kielbassa, K., Zang, R., Kittstein, W., Rincke, G., & Marks, F. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.1199 · Cited by 841 · see citing works

Activation of protein kinase C by tyrosine phosphorylation in response to H 2 O 2

Konishi, H., Tanaka, M., Takemura, Y., Matsuzaki, H., Ono, Y., Kikkawa, U., & Nishizuka, Y. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11233 · Cited by 604 · see citing works

Oxidative stress and glycemic regulation

Ceriello, A. (2000) · Metabolism · doi:10.1016/s0026-0495(00)80082-7 · Cited by 550 · see citing works

Insulin-stimulated Hydrogen Peroxide Reversibly Inhibits Protein-tyrosine Phosphatase 1B in Vivo and Enhances the Early Insulin Action Cascade

Mahadev, K., Zilbering, A., Zhu, L., & Goldstein, B. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100109200 · Cited by 509 · see citing works

Protein Kinase C–Dependent Increase in Reactive Oxygen Species (ROS) Production in Vascular Tissues of Diabetes: Role of Vascular NAD(P)H Oxidase

Inoguchi, T., Sonta, T., Tsubouchi, H., Etoh, T., Kakimoto, M., Sonoda, N., Sato, N., Sekiguchi, N., Kobayashi, K., Sumimoto, H., et al. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000077407.90309.65 · Cited by 435 · see citing works

Expression of phagocyte NADPH oxidase components in human endothelial cells

Jones, S. A., O’Donnell, V. B., Wood, J. D., Broughton, J. P., Hughes, E. J., & Jones, O. T. (1996) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1996.271.4.h1626 · Cited by 427 · see citing works

Phosphorylation of p47 p hox Sites by PKC α, βΙΙ, δ, and ζ: Effect on Binding to p22 p hox and on NADPH Oxidase Activation

Fontayne, A., Dang, P. M., Gougerot‐Pocidalo, M., & Benna, J. E. (2002) · Biochemistry · doi:10.1021/bi011953s · Cited by 412 · see citing works

Insulin action and insulin resistance in human skeletal muscle

Zierath, J. R., Krook, A., & Wallberg-Henriksson, H. (2000) · Diabetologia · doi:10.1007/s001250051457 · Cited by 367 · see citing works

Hydrogen Peroxide Generated during Cellular Insulin Stimulation Is Integral to Activation of the Distal Insulin Signaling Cascade in 3T3-L1 Adipocytes

Mahadev, K., Wu, X., Zilbering, A., Zhu, L., Lawrence, J. T. R., & Goldstein, B. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105061200 · Cited by 298 · see citing works

Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: Evidence for an involvement of protein kinase C

Heitzer, T. A., Wenzel, U. O., Hink, U., Krollner, D., Skatchkov, M. P., Stahl, R. A. K., Macharzina, R. R., Bräsen, J. H., Meinertz, T., & Münzel, T. F. (1999) · Kidney International · doi:10.1046/j.1523-1755.1999.00229.x · Cited by 245 · see citing works

Acute hyperglycemia induces an oxidative stress in healthy subjects

Marfella, R., Quagliaro, L., Nappo, F., Ceriello, A., & Giugliano, D. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13727 · Cited by 242 · see citing works

Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity

Davis, P. D., Elliott, L. H., Harris, W. R., Hill, C. H., Hurst, S. A., Keech, E., Kumar, M. K. H., Lawton, G., Nixon, J., & Wilkinson, S. E. (1992) · Journal of Medicinal Chemistry · doi:10.1021/jm00084a004 · Cited by 213 · see citing works

Biological effects of aminoguanidine: An update

Nilsson, B. (1999) · Inflammation Research · doi:10.1007/s000110050495 · Cited by 212 · see citing works

Translocation of Glomerular p47phox and p67phox by Protein Kinase C-β Activation Is Required for Oxidative Stress in Diabetic Nephropathy

Kitada, M., Koya, D., Sugimoto, T., Isono, M., Araki, S., Kashiwagi, A., & Haneda, M. (2003) · Diabetes · doi:10.2337/diabetes.52.10.2603 · Cited by 204 · see citing works

Protein kinase C-β contributes to NADPH oxidase activation in neutrophils

Dekker, L. V., Leitges, M., Altschuler, G. M., MISTRY, N., MCDERMOTT, A., Roes, J., & Segal, A. W. (2000) · Biochemical Journal · doi:10.1042/bj3470285 · Cited by 176 · see citing works

Increased glucose uptake promotes oxidative stress and PKC-δ activation in adipocytes of obese, insulin-resistant mice

Talior‐Volodarsky, I., Yarkoni, M., Bashan, N., & Eldar-Finkelman, H. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00044.2003 · Cited by 176 · see citing works

α-Tocopherol Decreases Superoxide Anion Release in Human Monocytes Under Hyperglycemic Conditions Via Inhibition of Protein Kinase C-α

Venugopal, S. K., Devaraj, S., Yang, T., & Jialal, I. (2002) · Diabetes · doi:10.2337/diabetes.51.10.3049 · Cited by 176 · see citing works

Inhibitors of protein kinase C

Gordge, P. C., & Ryves, W. J. (1994) · Cellular Signalling · doi:10.1016/0898-6568(94)90020-5 · Cited by 160 · see citing works

Insulin-induced Activation of NADPH-dependent H2O2 Generation in Human Adipocyte Plasma Membranes Is Mediated by Gαi2

Krieger‐Brauer, H. I., Medda, P. K., & KATHER, H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.15.10135 · Cited by 152 · see citing works

A Novel Assay System Implicates PtdIns(3,4)P2, PtdIns(3)P, and PKCδ in Intracellular Production of Reactive Oxygen Species by the NADPH Oxidase

Brown, G. E., Stewart, M. Q., Liu, H., Ha, V.-L., & Yaffe, M. B. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00005-4 · Cited by 139 · see citing works

p40 Is Phosphorylated on Threonine 154 and Serine 315 during Activation of the Phagocyte NADPH Oxidase

Bouin, A., Grandvaux, N., Vignais, P. V., & Fuchs, A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.46.30097 · Cited by 117 · see citing works

Activation and Mitochondrial Translocation of Protein Kinase Cδ Are Necessary for Insulin Stimulation of Pyruvate Dehydrogenase Complex Activity in Muscle and Liver Cells

Caruso, M., Maitan, M. A., Bifulco, G., Miele, C., Vigliottá, G., Oriente, F., Formisano, P., & Bèguinot, F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105451200 · Cited by 96 · see citing works

Activation of rat adipocyte glycogen synthase by insulins.

Lawrence, J. C., Guinovart, J. J., & Larner, J. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32736-9 · Cited by 93 · see citing works

Ligand-independent trans-Activation of the Platelet-derived Growth Factor Receptor by Reactive Oxygen Species Requires Protein Kinase C-δ and c-Src

Saito, S., Frank, G. D., Mifune, M., Ohba, M., Utsunomiya, H., Motley, E. D., Inagami, T., & Eguchi, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m208332200 · Cited by 92 · see citing works

Oxidative Stress

Kuroki, T., Isshiki, K., & King, G. L. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000077405.07888.07 · Cited by 92 · see citing works

Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats

Kashiwagi, A., Shinozaki, K., Nishio, Y., Maegawa, H., Maeno, Y., Kanazawa, A., Kojima, H., Haneda, M., Hidaka, H., Yasuda, H., et al. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.6.e976 · Cited by 89 · see citing works

Protein Kinase Cδ Mediates Insulin-Induced Glucose Transport in Primary Cultures of Rat Skeletal Muscle

Braiman, L., Alt, A., Kuroki, T., Ohba, M., Bak, A., Tennenbaum, T., & Sampson, S. R. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.12.0393 · Cited by 88 · see citing works

Direct interaction between p47phox and protein kinase C: evidence for targeting of protein kinase C by p47phox in neutrophils

Reeves, E. P., Dekker, L. V., Forbes, L. V., Wientjes, F. B., Grogan, A., Pappin, D., & Segal, A. W. (1999) · Biochemical Journal · doi:10.1042/bj3440859 · Cited by 82 · see citing works

A Phosphatidic Acid-activated Protein Kinase and Conventional Protein Kinase C Isoforms Phosphorylate p22 , an NADPH Oxidase Component

Regier, D. S., Waite, K. A., Wallin, R., & McPhail, L. C. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.51.36601 · Cited by 81 · see citing works

Requirement of Ca2+and PKCδ for Janus Kinase 2 Activation by Angiotensin II: Involvement of PYK2

Frank, G. D., Saito, S., Motley, E. D., Sasaki, T., Ohba, M., Kuroki, T., Inagami, T., & Eguchi, S. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.2.0768 · Cited by 75 · see citing works

Regulation of human eosinophil NADPH oxidase activity: A central role for PKCδ

Bankers‐Fulbright, J. L., Kita, H., Gleich, G. J., & O’Grady, S. M. (2001) · Journal of Cellular Physiology · doi:10.1002/jcp.10022 · Cited by 72 · see citing works

Roles for βII-Protein Kinase C and RACK1 in Positive and Negative Signaling for Superoxide Anion Generation in Differentiated HL60 Cells

Korchak, H. M., & Kilpatrick, L. E. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008326200 · Cited by 63 · see citing works

PKCδ Activation

Shen, S., Alt, A., Wertheimer, E., Gartsbein, M., Kuroki, T., Ohba, M., Braiman, L., Sampson, S. R., & Tennenbaum, T. (2001) · Diabetes · doi:10.2337/diabetes.50.2.255 · Cited by 57 · see citing works

Src tyrosine kinase regulates insulin-induced activation of protein kinase C (PKC) δ in skeletal muscle

Rosenzweig, T., Aga‐Mizrachi, S., Bak, A., & Sampson, S. R. (2004) · Cellular Signalling · doi:10.1016/j.cellsig.2004.03.015 · Cited by 47 · see citing works

Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress

Meyer, F., Fiala, E. S., & Westendorf, J. (2000) · Toxicology · doi:10.1016/s0300-483x(00)00140-2 · Cited by 38 · see citing works

Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives.

Bhatti, J. S., Sehrawat, A., Mishra, J., Sidhu, I. S., Navik, U., Khullar, N., Kumar, S., Bhatti, G. K., & Reddy, P. (2022) · Free Radical Biology & Medicine · doi:10.1016/j.freeradbiomed.2022.03.019 · Cited by 649 · see citing works

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

Johnson, A. R., Justin Milner, J., & Makowski, L. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2012.01151.x · Cited by 603 · see citing works

Positive and Negative Regulation of Insulin Signaling by Reactive Oxygen and Nitrogen Species

Bashan, N., Kovsan, J., Kachko, I., Ovadia, H., & Rudich, A. (2009) · Physiological Reviews · doi:10.1152/physrev.00014.2008 · Cited by 542 · see citing works

Mitogenic signalling and the p16INK4a–Rb pathway cooperate to enforce irreversible cellular senescence

Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S.-I., Tahara, H., Nakayama, K., Nakayama, K. I., Ide, T., Saya, H., & Hara, E. (2006) · Nature Cell Biology · doi:10.1038/ncb1491 · Cited by 528 · see citing works

Endothelial Dysfunction: Is There a Hyperglycemia-Induced Imbalance of NOX and NOS?

Meza, C. A., La Favor, J. D., Kim, D.-H., & Hickner, R. C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153775 · Cited by 323 · see citing works

Rottlerin: an inappropriate and ineffective inhibitor of PKCδ

Soltoff, S. P. (2007) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2007.07.003 · Cited by 312 · see citing works

Oxidative and Inflammatory Pathways in Parkinson’s Disease

Miller, R. L., James-Kracke, M., Sun, G. Y., & Sun, A. Y. (2009) · Neurochemical Research · doi:10.1007/s11064-008-9656-2 · Cited by 306 · see citing works

Oxidative stress and metabolic pathologies: from an adipocentric point of view

Le Lay, S., Simard, G., Martinez, M. C., & Andriantsitohaina, R. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/908539 · Cited by 291 · see citing works

A review of the molecular mechanisms of hyperglycemia‐induced free radical generation leading to oxidative stress

Yaribeygi, H., Atkin, S., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27164 · Cited by 226 · see citing works

Role of the JAK/STAT signaling pathway in diabetic nephropathy

Marrero, M. B., Banes‐Berceli, A. K. L., Stern, D. M., & Eaton, D. C. (2006) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00181.2005 · Cited by 218 · see citing works

Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species

Sudarshan, S., Sourbier, C., Kong, H.-S., Block, K., Romero, V. A. V., Yang, Y., Galindo, C., Mollapour, M., Scroggins, B., Goode, N., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00483-09 · Cited by 217 · see citing works

Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?

Correia‐Melo, C., Hewitt, G., & Passos, J. F. (2014) · Longevity & Healthspan · doi:10.1186/2046-2395-3-1 · Cited by 195 · see citing works

Some HIV Antiretrovirals Increase Oxidative Stress and Alter Chemokine, Cytokine or Adiponectin Production in Human Adipocytes and Macrophages

Lagathu, C., Eustace, B. K., Prot, M., Frantz, D., Gu, Y., Bastard, J., Maachi, M., Azoulay, S., Briggs, M., Caron, M., et al. (2007) · Antiviral Therapy · doi:10.1177/135965350701200407 · Cited by 185 · see citing works

Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

Wu, W.-S., Wu, J.-R., & Hu, C.-T. (2008) · Cancer Metastasis Review · doi:10.1007/s10555-008-9112-4 · Cited by 172 · see citing works

Mitochondria: Are they causal players in cellular senescence?

Correia-Melo, C., & Passos, J. F. (2015) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2015.05.017 · Cited by 160 · see citing works

Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury☆

Budas, G. R., Churchill, E. N., & Mochly‐Rosen, D. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.04.005 · Cited by 152 · see citing works

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans

Bézy, O., Tran, T. T., Pihlajamäki, J., Suzuki, R., Emanuelli, B., Winnay, J., Mori, M. A., Haas, J. T., Biddinger, S. B., Leitges, M., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci46045 · Cited by 148 · see citing works

Metabolic Regulation of Adipose Tissue Macrophage Function in Obesity and Diabetes

Appari, M., Channon, K. M., & McNeill, E. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7060 · Cited by 148 · see citing works

Redox Control of Protein Kinase C: Cell- and Disease-Specific Aspects

Giorgi, C., Agnoletto, C., Baldini, C., Bononi, A., Bonora, M., Marchi, S., Missiroli, S., Patergnani, S., Poletti, F., Rimessi, A., et al. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2825 · Cited by 146 · see citing works

Sustained stress response after oxidative stress in trabecular meshwork cells.

Li, G., Luna, C., Liton, P. B., Navarro, I., Epstein, D. L., & González, P. (2007) · Europe PMC (PubMed Central) · Cited by 122 · see citing works

Reactive Oxygen Species Mediated Sustained Activation of Protein Kinase C α and Extracellular Signal-Regulated Kinase for Migration of Human Hepatoma Cell Hepg2

Wu, W.-S., Tsai, R.-K., Chang, C.-H., Wang, S., Wu, J.-R., & Chang, Y.-X. (2006) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-06-0096 · Cited by 104 · see citing works

FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress

Pereira, S., Park, E., Mori, Y., Haber, C. A., Han, P., Uchida, T., Stavar, L., Oprescu, A. I., Koulajian, K., Ivovic, A., et al. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00436.2013 · Cited by 109 · see citing works

Cytotoxicity of paraquat in microglial cells: Involvement of PKCδ- and ERK1/2-dependent NADPH oxidase

Miller, R. L., Sun, G. Y., & Sun, A. Y. (2007) · Brain Research · doi:10.1016/j.brainres.2007.06.046 · Cited by 99 · see citing works

Effects of spirulina on weight loss and blood lipids: A review

DiNicolantonio, J. J., Bhat, A. G., & OKeefe, J. (2020) · Open Heart · doi:10.1136/openhrt-2018-001003 · Cited by 98 · see citing works

Targeting tissue oxidative damage by means of cell signaling modulators: The antioxidant concept revisited

Leonarduzzi, G., Sottero, B., & Poli, G. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.08.003 · Cited by 96 · see citing works

PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection

Shio, M. T., Christian, J. G., Jung, J. Y., Chang, K. P., & Olivier, M. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003868 · Cited by 97 · see citing works

Respiration in Adipocytes is Inhibited by Reactive Oxygen Species

Wang, T., Si, Y., Shirihai, O. S., Si, H., Schultz, V., Corkey, R. F., Hu, L., Deeney, J. T., Guo, W., & Corkey, B. E. (2009) · Obesity · doi:10.1038/oby.2009.456 · Cited by 85 · see citing works

Regulation of TNF-induced oxygen radical production in human neutrophils: role of δ-PKC

Kilpatrick, L. E., Sun, S., Li, H., Vary, T. C., & Korchak, H. M. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.0408230 · Cited by 80 · see citing works

AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-δ: implications for vascular disease

Cai, W., Torreggiani, M., Zhu, L., Chen, X., He, C., Striker, G. E., & Vlassara, H. (2009) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00463.2009 · Cited by 78 · see citing works

Adipose stress-sensing kinases: linking obesity to malfunction

Rudich, A., Kanety, H., & Bashan, N. (2007) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2007.08.006 · Cited by 73 · see citing works

Oxidative stress biomarkers in type 2 diabetes mellitus for assessment of cardiovascular disease risk

Robson, R., Kundur, A., & Singh, I. (2017) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2017.12.029 · Cited by 70 · see citing works

Neurotensin induces IL-6 secretion in mouse preadipocytes and adipose tissues during 2,4,6,-trinitrobenzensulphonic acid-induced colitis

Koon, H., Kim, Y. S., Xu, H. J., Kumar, A., Zhao, D., Karagiannides, I., Dobner, P. R., & Pothoulakis, C. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903499106 · Cited by 67 · see citing works

Hormetic and regulatory effects of lipid peroxidation mediators in pancreatic beta cells

Maulucci, G., Daniel, B., Cohen, O., Avrahami, Y., & Sasson, S. (2016) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2016.03.001 · Cited by 63 · see citing works

Lecithin:Cholesterol Acyltransferase Deficiency Protects against Cholesterol-induced Hepatic Endoplasmic Reticulum Stress in Mice

Hager, L., Li, L., Pun, H., Liu, L., Hossain, M. A., Maguire, G. F., Naples, M., Baker, C., Magomedova, L., Tam, J., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.340919 · Cited by 61 · see citing works

Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase‐1 in patients with Type 2 diabetes and microangiopathy

Adaikalakoteswari, A., Balasubramanyam, M., Rema, M., & Mohan, V. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01879.x · Cited by 59 · see citing works

Reactive Oxygen Species Facilitate Translocation of Hormone Sensitive Lipase to the Lipid Droplet During Lipolysis in Human Differentiated Adipocytes

Krawczyk, S. A., Haller, J. F., Ferrante, T., Zoeller, R. A., & Corkey, B. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034904 · Cited by 59 · see citing works

1α,25‐Dihydroxyvitamin D3 Modulation of Adipocyte Reactive Oxygen Species Production

Sun, X., & Zemel, M. B. (2007) · Obesity · doi:10.1038/oby.2007.232 · Cited by 57 · see citing works

Reishi immuno‐modulation protein induces interleukin‐2 expression via protein kinase‐dependent signaling pathways within human T cells

Hsu, H., Hua, K., Wu, W., Hsu, J., Weng, S.-T., Lin, T., Liu, C., Hseu, R., & Huang, C. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21144 · Cited by 56 · see citing works

Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production

Lin, L., Pang, W., Chen, K., Wang, F., Gengler, J., Sun, Y., & Tong, Q. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00462.2011 · Cited by 54 · see citing works

Vitamin B2 deficiency enhances the pro-inflammatory activity of adipocyte, consequences for insulin resistance and metabolic syndrome development

Mazur-Biały, A. I., & Pocheć, E. (2017) · Life Sciences · doi:10.1016/j.lfs.2017.04.010 · Cited by 55 · see citing works

Modulation of PKC signaling and induction of apoptosis through suppression of reactive oxygen species and tumor necrosis factor receptor 1 (TNFR1): key role of quercetin in cancer prevention

Maurya, A. K., & Vinayak, M. (2015) · Tumor Biology · doi:10.1007/s13277-015-3634-5 · Cited by 53 · see citing works

Vascular endothelial cell injury: causes, molecular mechanisms, and treatments

Xia, T., Yu, J., Du, M., Chen, X., Wang, C., & Li, R. (2025) · MedComm · doi:10.1002/mco2.70057 · Cited by 51 · see citing works

Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions

Gargiulo, S., Sottero, B., Gamba, P., Chiarpotto, E., Poli, G., & Leonarduzzi, G. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.05.030 · Cited by 50 · see citing works

Antioxidant bilirubin works in multiple ways to reduce risk for obesity and its health complications

DiNicolantonio, J. J., McCarty, M. F., & O’Keefe, J. H. (2018) · Open Heart · doi:10.1136/openhrt-2018-000914 · Cited by 50 · see citing works

Serum Bilirubin Levels in Overweight and Obese Individuals: The Importance of Anti-Inflammatory and Antioxidant Responses

Žiberna, L., Pražnikar, Z. J., & Petelin, A. (2021) · Antioxidants · doi:10.3390/antiox10091352 · Cited by 48 · see citing works

Intracellular albumin overload elicits endoplasmic reticulum stress and PKC-delta/p38 MAPK pathway activation to induce podocyte apoptosis

Gonçalves, G. L., Costa-Pessoa, J. M., Thieme, K., Lins, B. B., & Oliveira‐Souza, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-36933-9 · Cited by 40 · see citing works

Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2

Hu, C.-T., Wu, J.-R., Cheng, C.-C., Wang, S., Wang, H.-T., Lee, M.-C., Wang, L.-J., Pan, S.-M., Chang, T.-Y., & Wu, W.-S. (2011) · Clinical and Experimental Metastasis · doi:10.1007/s10585-011-9416-6 · Cited by 40 · see citing works

GO6976 prevents TNF‐α‐induced suppression of adiponectin expression in 3T3‐L1 adipocytes: Putative involvement of protein kinase C

Lim, J.-Y., Kim, W., & Park, S. I. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.09.012 · Cited by 38 · see citing works

Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats

Kiràly, M. A., Campbell, J. E., Park, E., Bates, H. E., Yue, J. T. Y., Rao, V., Matthews, S. G., Bikopoulos, G. J., Rozakis-Adcock, M., Giacca, A., et al. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90575.2008 · Cited by 37 · see citing works

Retinol as electron carrier in redox signaling, a new frontier in vitamin A research.

Hämmerling, U. (2016) · PubMed Central · doi:10.3978/j.issn.2304-3881.2016.01.02 · Cited by 35 · see citing works

Protective effect of 4,4'-diaminodiphenylsulfone against paraquat-induced mouse lung injury

Cho, S. C., Rhim, J. H., Choi, H. R., Son, Y. H., Lee, S. J., Song, K.-Y., & Park, S. C. (2011) · Experimental & Molecular Medicine · doi:10.3858/emm.2011.43.9.060 · Cited by 35 · see citing works

Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase CβII in the diabetic fat tissue

Liberman, Z., Plotkin, B., Tennenbaum, T., & Eldar-Finkelman, H. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00050.2008 · Cited by 32 · see citing works

Current Views of the Fat Cell as an Endocrine Cell: Lipotoxicity

Tchkonia, T., Corkey, B. E., & Kirkland, J. L. (2007) · Springer eBooks · doi:10.1007/978-0-387-32164-6_6 · Cited by 30 · see citing works

Involvement of protein kinase C delta in the alteration of mitochondrial mass in human cells under oxidative stress

Lee, C.-F., Chen, Y.-C., Liu, C., & Wei, Y. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.02.008 · Cited by 30 · see citing works

Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease

McCarty, M. F. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.06.029 · Cited by 30 · see citing works

Involvement of protein kinase Cδ in induction of apoptosis by cationic liposomes in macrophage‐like RAW264.7 cells

Arisaka, M., Nakamura, T., Yamada, A., Negishi, Y., & Aramaki, Y. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.01.055 · Cited by 28 · see citing works

Insulin resistance, adipokines, and oxidative stress in nondiabetic, hypercholesterolemic patients: leptin as an 8-epi-prostaglandin F2 determinant

Shin, M., Lee, J. H., Jang, Y., Park, E., Oh, J., Chung, J. H., & Chung, N. (2006) · Metabolism · doi:10.1016/j.metabol.2006.02.020 · Cited by 28 · see citing works

Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart

Gharib, M., Tao, H., Fungwe, T. V., & Hajri, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155611 · Cited by 27 · see citing works

Hypoadiponectinemia as a Marker of Adipocyte Dysfunction—Part II: The Functional Significance of Low Adiponectin Secretion

Stern, N., Osher, E., & Greenman, Y. (2007) · Journal of the CardioMetabolic Syndrome · doi:10.1111/j.1559-4564.2007.07297.x · Cited by 27 · see citing works

Amphetamine-evoked changes of oxidative stress and neuropeptide Y gene expression in hypothalamus: Regulation by the protein kinase C-δ signaling

Kuo, D., Yang, S., Chu, S., Chu, S., Chen, C.-H., & Hsieh, Y. (2009) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2009.03.013 · Cited by 26 · see citing works

Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line

Marques, A. P., Rosmaninho‐Salgado, J., Estrada, M. F., Cortez, V., Nobre, R. J., & Cavadas, C. (2016) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2016.12.005 · Cited by 26 · see citing works

Molecular interactions of serotonin (5-HT) and endothelin-1 in vascular smooth muscle cells: in vitro and ex vivo analyses

Bhaskaran, S., Zaluski, J., & Banes‐Berceli, A. K. L. (2013) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00247.2013 · Cited by 23 · see citing works

NOD1 activation induces oxidative stress via NOX1/4 in adipocytes

Sharma, A., Singh, S., Ahmad, S., Gulzar, F., Schertzer, J. D., & Tamrakar, A. K. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.11.036 · Cited by 23 · see citing works

Insulin generates free radicals in human fibroblasts ex vivo by a protein kinase C-dependent mechanism, which is inhibited by pravastatin

Ceolotto, G., Papparella, I., Lenzini, L., Sartori, M., Mazzoni, M., Iori, E., Franco, L., Gallo, A., de Kreutzenberg, S. V., Tiengo, A., et al. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.04.015 · Cited by 23 · see citing works

PKCδ is activated in the liver of obese Zucker rats and mediates diet-induced whole body insulin resistance and hepatocyte cellular insulin resistance

Greene, M. W., Burrington, C. M., Luo, Y., Ruhoff, M. S., Lynch, D. T., & Chaithongdi, N. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.10.008 · Cited by 21 · see citing works

PKCδ phosphorylation is an upstream event of GSK3 inactivation-mediated ROS generation in TGF-β1-induced senescence

Byun, H., Jung, H.-J., Kim, M.-J., & Yoon, G. (2014) · Free Radical Research · doi:10.3109/10715762.2014.929120 · Cited by 21 · see citing works

Salsalate may have broad utility in the prevention and treatment of vascular disorders and the metabolic syndrome

McCarty, M. F. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2009.12.027 · Cited by 21 · see citing works

PKCδ regulates hepatic triglyceride accumulation and insulin signaling in Leprdb/db mice

Zhang, J., Burrington, C. M., Davenport, S. K., Johnson, A. K., Horsman, M. J., Chowdhry, S., & Greene, M. W. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.07.048 · Cited by 19 · see citing works

Glycated human serum albumin enhances macrophage inflammatory protein-1β mRNA expression through protein kinase C-δ and NADPH oxidase in macrophage-like differentiated U937 cells

Higai, K., Satake, M., Nishioka, H., Azuma, Y., & Matsumoto, K. (2007) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2007.11.010 · Cited by 19 · see citing works

Elevated expression of protein kinase Cδ induces cell scattering upon serum deprivation

Chen, C.-L., Chan, P., Wang, S.-H., Pan, Y.-R., & Chen, H.-C. (2010) · Journal of Cell Science · doi:10.1242/jcs.069765 · Cited by 19 · see citing works

Alterations of NADPH Oxidase Activity in Rat Pancreatic Islets Induced by a High-Fat Diet

Valle, M. M. R., Graciano, M. F. R., de Oliveira, E. R. L., Camporez, J. P., Akamine, E. H., Carvalho, C. R. D. O., Curi, R., & Carpinelli, Â. R. (2011) · Pancreas · doi:10.1097/mpa.0b013e31820569d0 · Cited by 17 · see citing works

Role of PKCδ in Enhanced Expression of Gqα/PLCβ1 Proteins and VSMC Hypertrophy in Spontaneously Hypertensive Rats

Atef, M. E., & Anand‐Srivastava, M. B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157955 · Cited by 17 · see citing works

Relationship between Insulin Resistance and Lipid Peroxidation and Antioxidant Vitamins in Hypercholesterolemic Patients

Shin, M., Park, E., Lee, J. H., & Chung, N. (2005) · Annals of Nutrition and Metabolism · doi:10.1159/000090499 · Cited by 17 · see citing works

Protein kinase C δ-dependent regulation of Ubiquitin-proteasome system function in breast cancer

Sun, S., Wu, Q., Song, J., & Sun, S. (2017) · Cancer Biomarkers · doi:10.3233/cbm-170451 · Cited by 16 · see citing works

Association Between Serum CK-18 Levels and the Degree of Liver Damage in Fructose-Induced Metabolic Syndrome

Bratoeva, K. Z., Nikolova, S., Merdzhanova, A., Stoyanov, G. S., Dimitrová, E., Kashlov, Y., Conev, N. V., & Radanova, M. A. (2018) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2017.0162 · Cited by 16 · see citing works

Combined influence of dietary restriction and treadmill running on MCP-1 and the expression of oxidative stress-related mRNA in the adipose tissue in obese mice

Ahn, N., & Kim, K. (2014) · Physical Activity and Nutrition · doi:10.5717/jenb.2014.18.3.311 · Cited by 13 · see citing works

Peroxisome Proliferator-Activated Receptor γ (PPARγ)-Independent Specific Cytotoxicity against Immature Adipocytes Induced by PPARγ Antagonist T0070907

Kawahara, A., Haraguchi, N., Tsuchiya, H., Ikeda, Y., Hama, S., & Kogure, K. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00024 · Cited by 13 · see citing works

Erythroid cell differentiation is characterized by nuclear matrix localization and phosphorylation of protein kinases C (PKC) α, δ, and ζ

Marchisio, M., Santavenere, E., Paludi, M., Gaspari, A. R., Lanuti, P., Bascelli, A., Ercolino, E., Baldassarre, A. D., & Miscia, S. (2005) · Journal of Cellular Physiology · doi:10.1002/jcp.20364 · Cited by 13 · see citing works

Protective role of S-Adenosylmethionine against fructose-induced oxidative damage in obesity

Bratoeva, K. Z., Radanova, M. A., Merdzhanova, A., & Donev, I. S. (2017) · Journal of Mind and Medical Sciences · doi:10.22543/7674.42.p163171 · Cited by 13 · see citing works

The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review

Sokary, S., Bawadi, H. A., Zakaria, Z. Z., & Al‐Asmakh, M. (2024) · Journal of Dietary Supplements · doi:10.1080/19390211.2023.2301366 · Cited by 12 · see citing works

Modification of microsomal 11β-HSD1 activity by cytosolic compounds: Glutathione and hexose phosphoesters

McCormick, K. L., Wang, X., & Mick, G. J. (2008) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2008.04.003 · Cited by 11 · see citing works

Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues

Kojima, K., Motoshima, H., Tsutsumi, A., Igata, M., Matsumura, T., Kondo, T., Kawashima, J., Ichinose, K., Furukawa, N., Inukai, K., et al. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.09.007 · Cited by 10 · see citing works

Retinol as a cofactor for PKCδ‐mediated impairment of insulin sensitivity in a mouse model of diet‐induced obesity

Shabrova, E. V., Hoyos, B. E., Vinogradov, V., Kim, Y., Wassef, L., Leitges, M., Quadro, L., & Hämmerling, U. (2015) · The FASEB Journal · doi:10.1096/fj.15-281543 · Cited by 10 · see citing works

Superoxide Anion Generation, Its Pathological Cellular and Molecular Roles and Pharmacological Targeting in Inflammatory Pain: Lessons from the Potassium Superoxide Model

Bianchini, B. H. S., Martelossi-Cebinelli, G., Carneiro, J. A., Rasquel-Oliveira, F. S., Casagrande, R., & Verri, W. A., Jr. (2025) · Future Pharmacology · doi:10.3390/futurepharmacol5040060 · Cited by 10 · see citing works

Genetic dissection of susceptibility genes for diabetes and related phenotypes on mouse chromosome 14 by means of congenic strains

Babaya, N., Ueda, H., Noso, S., Hiromine, Y., Itoi‐Babaya, M., Kobayashi, M., Fujisawa, T., & Ikegami, H. (2014) · BMC Genetics · doi:10.1186/s12863-014-0093-8 · Cited by 9 · see citing works

Mechanisms underlying fat-induced hepatic insulin resistaNce

Park, E., & Giacca, A. (2007) · Future Lipidology · doi:10.2217/17460875.2.5.503 · Cited by 9 · see citing works

NAPDH oxidase mediates glucolipotoxicity-induced beta cell dysfunction – Clinical implications

McCarty, M. F., Barroso-Aranda, J., & Contreras, F. (2009) · Medical Hypotheses · doi:10.1016/j.mehy.2008.09.062 · Cited by 8 · see citing works

Vitamin D Modulation of Adipocyte Function

Zemel, M. B., & Sun, X. (2010) · Humana Press eBooks · doi:10.1007/978-1-60327-303-9_17 · Cited by 8 · see citing works

Single-cell transcriptomic analysis of the adult mouse spinal cordPreprint

Blum, J. A., Klemm, S. L., Nakayama, L., Kathiria, A. S., Guttenplan, K. A., Hoang, P. T., Shadrach, J. L., Kaltschmidt, J. A., Greenleaf, W. J., & Gitler, A. D. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.16.992958 · Cited by 8 · see citing works

Activation of protein kinase C delta reduces hepatocellular damage in ischemic preconditioned rat liver

Yun, N., & Lee, S. (2013) · Journal of Surgical Research · doi:10.1016/j.jss.2013.07.005 · Cited by 7 · see citing works

Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance?

DiNicolantonio, J. J., McCarty, M. F., & O’Keefe, J. H. (2019) · Open Heart · doi:10.1136/openhrt-2018-000897 · Cited by 7 · see citing works

Protein kinase CβI interacts with the β1-adrenergic signaling pathway to attenuate lipolysis in rat adipocytes

Nakamura, J. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2008.03.007 · Cited by 7 · see citing works

Role of oxidative stress in the pathogenesis of metabolic syndrome

Chakrabarti, S. S., Saso, L., Bala, S., Saha, S., Profumo, E., Buttari, B., & Chakrabarti, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-85732-1.00021-9 · Cited by 6 · see citing works

A specific small-molecule inhibitor of protein kinase CδI activity improves metabolic dysfunction in human adipocytes from obese individuals

Sparks, R. P., Lui, A., Bader, D., Patel, R. S., Murr, M. M., Guida, W. C., Fratti, R. A., & Patel, N. A. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.008777 · Cited by 6 · see citing works

Protein kinase C-dependent antilipolysis by insulin in rat adipocytes

Nakamura, J. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2007.06.004 · Cited by 5 · see citing works

Adipocyte inducible 6-phosphofructo-2-kinase suppresses adipose tissue inflammation and promotes macrophage anti-inflammatory activation

Xu, H., Zhu, B., Li, H., Jiang, B., Wang, Y., Yin, Q., Cai, J. J., Glaser, S. S., Francis, H., Alpini, G. D., et al. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108764 · Cited by 5 · see citing works

Antioxidants: Pharmacothearapeutic Boon for Diabetes

Suresh, V., Reddy, A., Muthukumar, P., & Selvam, T. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.98587 · Cited by 7 · see citing works

Whole Exome Sequencing in 26 Saudi Patients Expands the Mutational and Clinical Spectrum of Diabetic Nephropathy

Elfaki, I., Mir, R., Almowallad, S. J., Al-Massabi, R. F., Albalawi, W., Albalawi, A. D., Bhat, A. A., Barnawi, J., Tayeb, F. J., Jalal, M. M., et al. (2025) · Medicina · doi:10.3390/medicina61061017 · Cited by 3 · see citing works

Insulin and the Physiology of Carbohydrate Metabolism

Pereira, S., & Giacca, A. (2011) · Energy balance and cancer · doi:10.1007/978-1-4419-9911-5_1 · Cited by 3 · see citing works

Increased glucose uptake promotes oxidative stress and PKC-δ activation in adipocytes of obese, insulin-resistant mice

Talior‐Volodarsky, I., Yarkoni, M., Bashan, N., & Eldar-Finkelman, H. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00044.2003 · Cited by 176 · see citing works

FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress

Pereira, S., Park, E., Mori, Y., Haber, C. A., Han, P., Uchida, T., Stavar, L., Oprescu, A. I., Koulajian, K., Ivovic, A., et al. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00436.2013 · Cited by 109 · see citing works

Adipocyte-Specific Deficiency of NADPH Oxidase 4 Delays the Onset of Insulin Resistance and Attenuates Adipose Tissue Inflammation in Obesity

den Hartigh, L. J., Omer, M., Goodspeed, L., Wang, S., Wietecha, T., O’Brien, K. D., & Han, C. Y. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.116.308749 · Cited by 110 · see citing works

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

Inoguchi, T., Li, P., Umeda, F., Yu, H. Y., Kakimoto, M., Imamura, M., Aoki, T., Etoh, T., Hashimoto, T., Naruse, M., et al. (2000) · Diabetes · doi:10.2337/diabetes.49.11.1939 · Cited by 1,577 · see citing works

PKCδ is activated in the liver of obese Zucker rats and mediates diet-induced whole body insulin resistance and hepatocyte cellular insulin resistance

Greene, M. W., Burrington, C. M., Luo, Y., Ruhoff, M. S., Lynch, D. T., & Chaithongdi, N. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.10.008 · Cited by 21 · see citing works