Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

Vascular Contributions to Cognitive Impairment and Dementia: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Gorelick, P. B., Scuteri, A., Black, S. E., DeCarli, C., Greenberg, S. M., Iadecola, C., Launer, L. J., Laurent, S., Lopez, O. L., Nyenhuis, D., et al. (2011) · Stroke · doi:10.1161/str.0b013e3182299496 · Cited by 3,811

Interplay between Cortical Spreading Depolarization and Seizures

Kramer, D. R., Fujii, T., Ohiorhenuan, I. E., & Liu, C. Y. (2017) · Stereotactic and Functional Neurosurgery · doi:10.1159/000452841 · Cited by 3,721

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

Zlokovic, B. V. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.003 · Cited by 3,280

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack

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Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders

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Glial and neuronal control of brain blood flow

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

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Blood-brain barrier breakdown in the aging human hippocampus

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Perioperative neurocognition in elderly patients

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Microvascular Endothelial Function and Neurocognition Among Adults With Major Depressive Disorder

Smith, P. J., Blumenthal, J. A., Hinderliter, A. L., Watkins, L. L., Hoffman, B. M., & Sherwood, A. (2018) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2018.06.011 · Cited by 25

Reversal of cerebral hypoperfusion: a novel therapeutic target for the treatment of AD/ADRD?

Fan, F., & Roman, R. J. (2021) · GeroScience · doi:10.1007/s11357-021-00357-7 · Cited by 24

Neuroinflammation and blood–brain barrier dysfunction in cerebral small vessel disease: mechanisms, biomarkers, and therapeutic implications

Luo, L., & Qiao, S. (2026) · European journal of medical research · doi:10.1186/s40001-026-03840-z · Cited by 25

Hypoxic–hyperoxic conditioning and dementia

Mallet, R. T., Burtscher, J., Manukhina, E. B., Downey, H. F., Glazachev, O. S., Serebrovskaya, T. V., & Burtscher, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815854-8.00047-1 · Cited by 23

Capsaicin: A Potential Treatment to Improve Cerebrovascular Function and Cognition in Obesity and Ageing

Thornton, T., Mills, D. E., & Bliss, E. (2023) · Nutrients · doi:10.3390/nu15061537 · Cited by 26

A decade of aging in healthy older adults: longitudinal findings on cerebrovascular and cognitive health

Weijs, R. W. J., Oudegeest‐Sander, M. H., Vloet, J. I. A., Hopman, M. T. E., Claassen, J. A. H. R., & Thijssen, D. H. J. (2023) · GeroScience · doi:10.1007/s11357-023-00790-w · Cited by 23

Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells

Sun, R., He, T., Pan, Y., & Katušić, Z. S. (2018) · Aging · doi:10.18632/aging.101362 · Cited by 25

Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency

Reagan, A. M., Gu, X., Paudel, S., Ashpole, N. M., Zalles, M., Sonntag, W. E., Ungvari, Z. I., Csiszár, A., Otalora, L., Freeman, W. M., et al. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.06.039 · Cited by 23

Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability

Tarantini, S., Yabluchanskiy, A., Fülöp, G. Á., Kiss, T., Perz, A., O’Connor, D., Johnson, E., Sorond, F. A., Ungvari, Z. I., & Csiszár, A. (2018) · The Journals of Gerontology Series A · doi:10.1093/gerona/gly242 · Cited by 23

Serum Exosomal mir-340-5p Promotes Angiogenesis in Brain Microvascular Endothelial Cells During Oxygen-Glucose Deprivation

Xu, C., Yu, H., Chen, B., Ma, Y., & Lv, P. (2022) · Neurochemical Research · doi:10.1007/s11064-021-03492-x · Cited by 23

Sex-specific mechanisms in vascular aging: exploring cellular and molecular pathways in the pathogenesis of age-related cardiovascular and cerebrovascular diseases

Ungvari, A., Gulej, R., Patai, R., Papp, Z., Tóth, A., Szabó, A. Á., Podesser, B. K., Sótonyi, P., Benyó, Z., Yabluchanskiy, A., et al. (2025) · GeroScience · doi:10.1007/s11357-024-01489-2 · Cited by 22

The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke

Xu, M., Wang, M. M., Gao, Y., Keep, R. F., & Shi, Y. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.07.008 · Cited by 22

Chronic neurological disorders and related comorbidities: Role of age-associated physiological changes

Roca, F., Lang, P. O., & Chassagne, P. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-12-804766-8.00007-8 · Cited by 23

Fatal attraction – The role of hypoxia when alpha-synuclein gets intimate with mitochondria

Burtscher, J., Syed, M. M. K., Keller, M. A., Lashuel, H. A., & Millet, G. P. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.07.017 · Cited by 25

Inward Rectifier Potassium Channels: Membrane Lipid-Dependent Mechanosensitive Gates in Brain Vascular Cells

Sancho, M., Fletcher, J., & Welsh, D. G. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.869481 · Cited by 25

Cerebral microvascular dysfunction and neurodegeneration in dementia

Han, F. (2019) · Stroke and Vascular Neurology · doi:10.1136/svn-2018-000213 · Cited by 22

Pathologic sequelae of vascular cognitive impairment and dementia sheds light on potential targets for intervention

Linton, A. E., Weekman, E. M., & Wilcock, D. M. (2021) · Cerebral Circulation - Cognition and Behavior · doi:10.1016/j.cccb.2021.100030 · Cited by 21

Cerebrovascular Reactivity and Neurovascular Coupling in Multiple Sclerosis—A Systematic Review

Vestergaard, M. B., Frederiksen, J. L., Larsson, H. B. W., & Cramer, S. P. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.912828 · Cited by 23

Hyperinsulinemia alters insulin receptor presentation and internalization in brain microvascular endothelial cells

Watson, L. S., Wilken-Resman, B., Williams, A., DiLucia, S., Sánchez, G., McLeod, T., & Sims‐Robinson, C. (2022) · Diabetes and Vascular Disease Research · doi:10.1177/14791641221118626 · Cited by 26

Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia

Turana, Y., Shen, R. K., Nathaniel, M., Chia, Y. C., Li, Y., & Kario, K. (2022) · Journal of Clinical Hypertension · doi:10.1111/jch.14559 · Cited by 22

Microvascular Dysfunction as a Possible Link Between Heart Failure and Cognitive Dysfunction

Hillier, E. L., Covone, J., Fischer, K., Chen, H. Y., Hafyane, T., & Friedrich, M. G. (2023) · Circulation Heart Failure · doi:10.1161/circheartfailure.122.010117 · Cited by 21

A functional cerebral endothelium is necessary to protect against cognitive decline

Trigiani, L. J., Bourourou, M., Lacalle-Aurioles, M., Lecrux, C., Hynes, A., Spring, S., Fernandes, D. J., Sled, J. G., Lesage, F., Schwaninger, M., et al. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211045438 · Cited by 21

Sensory Neuromodulation

Black, R. D., & Rogers, L. L. (2020) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2020.00012 · Cited by 23

Cerebral blood flow predicts multiple demand network activity and fluid intelligence across the adult lifespan

Wu, S., TYLER, L. K., Henson, R. N., Rowe, J. B., Cam‐CAN, & Tsvetanov, K. A. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.09.006 · Cited by 25

Deciphering mitochondrial dysfunction: Pathophysiological mechanisms in vascular cognitive impairment

He, Y., He, T., Li, H., Chen, W., Zhong, B., Wu, Y., Chen, R., Hu, Y., Ma, H., Wu, B., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116428 · Cited by 22

Test–retest reliability of arterial spin labelling for cerebral blood flow in older adults with small vessel disease

Binnie, L. R., Pauls, M. M. H., Benjamin, P., Dhillon, M. K., Betteridge, S., Clarke, B. A., Ghatala, R., Hainsworth, F. A. H., Howe, F. A., Khan, U., et al. (2022) · Translational Stroke Research · doi:10.1007/s12975-021-00983-5 · Cited by 20

Cerebrovascular function and its association with systemic artery function and stiffness in older adults with and without mild cognitive impairment

Bailey, T. G., Klein, T., Menêses, A. L., Stefanidis, K. B., Ruediger, S. L., GREEN, D. J., Stuckenschneider, T., Schneider, S., & Askew, C. D. (2022) · European Journal of Applied Physiology · doi:10.1007/s00421-022-04956-w · Cited by 21

Retinal microvascular function is associated with the cerebral microcirculation as determined by intravoxel incoherent motion MRI

van Dinther, M., Voorter, P., Schram, M. T., Berendschot, T. T. J. M., Houben, A. J. H. M., Webers, C. A. B., van Oostenbrugge, R. J., Backes, W. H., Staals, J., & Jansen, J. F. A. (2022) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2022.120359 · Cited by 20

Ling-Yang-Gou-Teng-decoction prevents vascular dementia through inhibiting oxidative stress induced neurovascular coupling dysfunction

Zhao, X., Liu, J., Yang, S., Song, D., Wang, C., Chen, C., Li, X., Wang, Q., Ge, S., Yang, R., et al. (2018) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2018.03.015 · Cited by 20

Aging Impairs Cerebrovascular Reactivity at Preserved Resting Cerebral Arteriolar Tone and Vascular Density in the Laboratory Rat

Bálint, A. R., Puskás, T., Menyhárt, Á., Kozák, G., Szenti, I., Kónya, Z., Marek, T., Bari, F., & Farkas, E. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00301 · Cited by 22

Vascular Cognitive Impairment—The Molecular Basis and Potential Influence of the Gut Microbiota on the Pathological Process

Olejnik, P., & Golenia, A. (2024) · Cells · doi:10.3390/cells13231962 · Cited by 20

A Minimally Invasive Framework Reveals Region‐Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS‐ULM)

Negri, S., Nyúl‐Tóth, Á., Milan, M., Troyano‐Rodriguez, E., Tavakol, S., Ihuoma, J., Reyff, Z., Rudraboina, R., Gulej, R., Jang, R., et al. (2025) · Advanced Science · doi:10.1002/advs.202510754 · Cited by 19

Does coronaviruses induce neurodegenerative diseases? A systematic review on the neurotropism and neuroinvasion of SARS-CoV-2

ELBini-Dhouib, I. (2020) · Drug Discoveries & Therapeutics · doi:10.5582/ddt.2020.03106 · Cited by 19

The Association Between Perivascular Spaces and Cerebral Blood Flow, Brain Volume, and Cardiovascular Risk

Liu, S., Hou, B., You, H., Zhang, Y., Zhu, Y., Ma, C., Zuo, Z., & Feng, F. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.599724 · Cited by 19

Orthostatic Blood Pressure Change, Dizziness, and Risk of Dementia in the ARIC Study

Ma, Y., Zhang, Y., Coresh, J., Viswanathan, A., Sullivan, K., Walker, K. A., Liu, C., Lipsitz, L. A., Selvin, E., Sharrett, A. R., et al. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.21438 · Cited by 20

A high-resolution view of the heterogeneous aging endothelium

Dobner, S., Tóth, F., & de Rooij, L. P. M. H. (2024) · Angiogenesis · doi:10.1007/s10456-023-09904-6 · Cited by 23

The Neurovascular Unit: Focus on the Regulation of Arterial Smooth Muscle Cells

Quelhas, P., Baltazar, G., & Cairrão, E. (2019) · Current Neurovascular Research · doi:10.2174/1567202616666191026122642 · Cited by 19

Biomimetic Nanocarrier Targeting Drug(s) to Upstream-Receptor Mechanisms in Dementia: Focusing on Linking Pathogenic Cascades

D'Arrigo, J. S. (2020) · Biomimetics · doi:10.3390/biomimetics5010011 · Cited by 19

Obesity in Midlife Hampers Resting and Sensory‐Evoked Cerebral Blood Flow in Mice

Soleimanzad, H., Montaner, M., Ternier, G., Lemitre, M., Silvestre, J., Kassis, N., Giacobini, P., Magnan, C., Pain, F., & Gurden, H. (2020) · Obesity · doi:10.1002/oby.23051 · Cited by 19

Compromised Dynamic Cerebral Autoregulation in Patients with Epilepsy

Lv, S., Guo, Z., Jin, H., Sun, X., Jia, M., Ma, H., Lv, Y., Qiu, Q., Liu, J., & Yang, Y. (2018) · BioMed Research International · doi:10.1155/2018/6958476 · Cited by 18

Age-associated increases in middle cerebral artery pulsatility differ between men and women

Lefferts, W. K., Reed, K. S., Rosonke, R. E., Augustine, J. A., & Moreau, K. L. (2023) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00453.2023 · Cited by 18

Human herpesvirus reactivation and its potential role in the pathogenesis of post-acute sequelae of SARS-CoV-2 infection

Gáspár, Z., Szabó, B. G., Ceglédi, A., & Lakatos, B. (2024) · GeroScience · doi:10.1007/s11357-024-01323-9 · Cited by 24

Cognitive impairment in cerebrovascular diseases

Bogolepova, A. N., Mkhitaryan, E. A., & Levin, O. S. (2024) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202412404212 · Cited by 19

Cognitive impairment, endothelial biomarkers and mortality in maintenance haemodialysis patients: a prospective cohort study

de Medeiros, C. M. M. F., da Silva, B. R. D., Costa, B. G., Sartori, V. F., Meneses, G. C., Bezerra, G. F., Martins, A. M. C., & Libório, A. B. (2020) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfaa040 · Cited by 17

Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice

Tarantini, S., Yabluchanskiy, A., Lindsey, M. L., Csiszár, A., & Ungvari, Z. I. (2021) · GeroScience · doi:10.1007/s11357-021-00402-5 · Cited by 17

Cataloging the potential SNPs (single nucleotide polymorphisms) associated with quantitative traits, viz. BMI (body mass index), IQ (intelligence quotient) and BP (blood pressure): an updated review

Chauhan, W., Fatma, R., Wahab, A., & Afzal, M. (2022) · Egyptian Journal of Medical Human Genetics · doi:10.1186/s43042-022-00266-0 · Cited by 18

Non-pharmacological interventions for vascular health and the role of the endothelium

Weaver, S. R., Rendeiro, C., Lucas, R. A. I., Cable, N. T., Nightingale, T. E., McGettrick, H. M., & Lucas, S. J. E. (2022) · European Journal of Applied Physiology · doi:10.1007/s00421-022-05041-y · Cited by 17

Vascular smooth muscle cell-specific Igf1r deficiency exacerbates the development of hypertension-induced cerebral microhemorrhages and gait defects

Miller, L. R., Bickel, M. A., Vance, M. L., Vaden, H., Nagykaldi, D., Nyúl‐Tóth, Á., Bullen, E. C., Gautam, T., Tarantini, S., Yabluchanskiy, A., et al. (2024) · GeroScience · doi:10.1007/s11357-024-01090-7 · Cited by 17

Reduced Dynamic Coupling Between Spontaneous BOLD-CBF Fluctuations in Older Adults: A Dual-Echo pCASL Study

Chiacchiaretta, P., Cerritelli, F., Bubbico, G., Perrucci, M. G., & Ferretti, A. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00115 · Cited by 17

Cerebral macro- and microcirculatory blood flow dynamics in successfully treated chronic hypertensive patients with and without white mater lesions

Müller, M., Österreich, M., Lakatos, L.-B., & von Hessling, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-66317-x · Cited by 17

Effects of kynurenine pathway metabolites on choroid plexus volume, hemodynamic response, and spontaneous neural activity: A new mechanism for disrupted neurovascular communication and impaired cognition in mood disorders

Bravi, B., Verga, C., Palladini, M., Sara, P., Camilla, B., Sut, S., Dall’Acqua, S., Colombo, C., Comai, S., & Benedetti, F. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.01.025 · Cited by 18

The Gut-Brain Axis in Alzheimer’s Disease: Exploring Microbial Influences and Therapeutic Strategies

Mustafa, M. A., Vadia, N., Varma, P., Al‐Shaker, H., Mohanty, B., Dhyani, A., Kaur, I., Chauhan, A. S., & Garg, G. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05474-4 · Cited by 18

Cerebral Autoregulation during Orthostatic Challenge in Congenital Central Hypoventilation Syndrome

Vu, E. L., Dunne, E. C., Bradley, A., Zhou, A., Carroll, M. S., Rand, C. M., Brady, K. M., Stewart, T. M., & Weese-Mayer, D. E. (2021) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202103-0732oc · Cited by 16

(Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study

van der Heide, F. C. T., Foreman, Y. D., Franken, I., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J., Webers, C. A. B., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-22748-2 · Cited by 16

The Utility of Arterial Spin Labeling MRI in Medial Temporal Lobe as a Vascular Biomarker in Alzheimer’s Disease Spectrum: A Systematic Review and Meta-Analysis

Kapasouri, E. M., Ioannidis, D. C., Cameron, D., Vassiliou, V. S., & Hornberger, M. (2022) · Diagnostics · doi:10.3390/diagnostics12122967 · Cited by 17

Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study

Owens, C. D., Pinto, C. B., Mukli, P., Szarvas, Z., Péterfi, A., Detwiler, S., Olay, L., Olson, A. L., Li, G., Galván, V., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289508 · Cited by 16

Alzheimer’s Disease, Brain Injury, and C.N.S. Nanotherapy in Humans: Sonoporation Augmenting Drug Targeting

D'Arrigo, J. S. (2017) · Medical Sciences · doi:10.3390/medsci5040029 · Cited by 15

LRRTM4 and PCSK5 Genetic Polymorphisms as Markers for Cognitive Impairment in A Hypotensive Aging Population: A Genome-Wide Association Study in Taiwan

Chen, Y., Liu, Y., Tsai, S., Kuo, P., Huang, S.-S., & Lee, Y. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081124 · Cited by 17

Prospects for Diminishing the Impact of Nonamyloid Small-Vessel Diseases of the Brain

Joutel, A. (2019) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010818-021712 · Cited by 17

The effects of voluntary running on cerebrovascular morphology and spatial short-term memory in a mouse model of amyloidosis

Maliszewska‐Cyna, E., Vecchio, L. M., Thomason, L. A. M., Oore, J., Steinman, J., Joo, I. L., Dorr, A. E., McLaurin, J., Sled, J. G., Stefanovic, B., et al. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117269 · Cited by 17

Nanotargeting of Drug(s) for Delaying Dementia: Relevance of Covid-19 Impact on Dementia

D'Arrigo, J. S. (2020) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317520976761 · Cited by 16

Midlife aerobic exercise and dynamic cerebral autoregulation: associations with baroreflex sensitivity and central arterial stiffness

Tomoto, T., Repshas, J., Zhang, R., & Tarumi, T. (2021) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00243.2021 · Cited by 19

Insulin-Like Growth Factor-1 Differentially Modulates Glutamate-Induced Toxicity and Stress in Cells of the Neurogliovascular Unit

Hayes, C. A., Ashmore, B. G., Vijayasankar, A., Marshall, J. P. S., & Ashpole, N. M. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.751304 · Cited by 16

Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier

D'Arrigo, J. S. (2018) · Biomimetics · doi:10.3390/biomimetics3010004 · Cited by 15

Cortical thinning is associated with brain pulsatility in older adults: An MRI and NIRS study

Mohammadi, H., Peng, K., Kassab, A., Nigam, A., Bherer, L., Lesage, F., & Joanette, Y. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.05.002 · Cited by 18

The Effects of Aerobic Exercise Training on Cerebrovascular and Cognitive Function in Sedentary, Obese, Older Adults

Bliss, E., Wong, R. H. X., Howe, P. R. C., & Mills, D. E. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.892343 · Cited by 21

Effects of interventions on cerebral perfusion in the Alzheimer's disease spectrum: A systematic review

Marcolini, S., Frentz, I., Sánchez-Catasús, C. A., Mondragón, J. D., Feltes, P. K., van der Hoorn, A., Borra, R., Ikram, M. A., Dierckx, R., & Deyn, P. P. D. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101661 · Cited by 16

Forgetful, sad and old: Do vascular cognitive impairment and depression share a common pre-disease network and how is it impacted by ageing?

Sapsford, T., Johnson, S., Headrick, J. P., Branjerdporn, G., Adhikary, S. R., Sarfaraz, M., & Stapelberg, N. J. C. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.10.071 · Cited by 15

Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin

Faakye, J., Nyúl‐Tóth, Á., Gulej, R., Csík, B., Tarantini, S., Shanmugarama, S., Prodan, C. I., Mukli, P., Yabluchanskiy, A., Conley, S. M., et al. (2023) · GeroScience · doi:10.1007/s11357-023-00839-w · Cited by 15

Whole brain irradiation–induced endothelial dysfunction in the mouse brain

Kiss, T., Ungvari, A., Gulej, R., Nyúl‐Tóth, Á., Tarantini, S., Benyó, Z., Csík, B., Yabluchanskiy, A., Mukli, P., Csiszár, A., et al. (2023) · GeroScience · doi:10.1007/s11357-023-00990-4 · Cited by 15

Aging, mitochondrial dysfunction, and cerebral microhemorrhages: a preclinical evaluation of SS-31 (elamipretide) and development of a high-throughput machine learning-driven imaging pipeline for cerebromicrovascular protection therapeutic screening

Patai, R., Patel, K., Csík, B., Gulej, R., Nagaraja, R. Y., Nagy, D., Chandragiri, S. S., Shanmugarama, S., Kordestan, K. V., Nagykaldi, M., et al. (2025) · GeroScience · doi:10.1007/s11357-025-01634-5 · Cited by 17

The presence of cerebral white matter lesions and lower skin microvascular perfusion predicts lower cognitive performance in type 1 diabetes patients with retinopathy but not in healthy controls—A longitudinal study

Emanuel, A. L., van Duinkerken, E., Wattjes, M. P., Klein, M., Barkhof, F., Snoek, F. J., Diamant, M., Eringa, E. C., IJzerman, R. G., & Serné, E. H. (2019) · Microcirculation · doi:10.1111/micc.12530 · Cited by 15

Patients with Alzheimer’s Disease Have Increased Levels of Insulin-like Growth Factor-I in Serum but not in Cerebrospinal Fluid

Horváth, A., Salman, Z., Quinlan, P. S., Wallin, A., & Svensson, J. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-190921 · Cited by 15

First‐in‐human trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of zagociguat (CY6463), a CNS‐penetrant soluble guanylyl cyclase stimulator

van Kraaij, S. J. W., Gal, P., Borghans, L. G. J. M., Klaassen, E. S., Dijkstra, F. M., Winrow, C. J., Glasser, C. E., & Groeneveld, G. J. (2023) · Clinical and Translational Science · doi:10.1111/cts.13537 · Cited by 15

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Variation within the visually evoked neurovascular coupling response of the posterior cerebral artery is not influenced by age or sex

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Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV

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Endostatin as a Mediator Between Endothelial Function and Cognitive Performance in Those at Risk for Vascular Cognitive Impairment

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Mild traumatic brain injury-induced persistent blood–brain barrier disruption is prevented by cyclosporine A treatment in hypertension

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IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice

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The physiologic complexity of beat‐to‐beat blood pressure is associated with age‐related alterations in blood pressure regulation

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Angiotensin II and Amyloid-β Synergistically Induce Brain Vascular Smooth Muscle Cell Senescence

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You Are as Old as Your Arteries ‐ And Microvessels

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