Disequilibrium between the classic renin-angiotensin system and its opposing arm in SARS-CoV-2-related lung injury

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Xiang, J., Wang, Y., Song, B., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30566-3 · Cited by 27,263 · see citing works

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.052 · Cited by 20,286 · see citing works

Corrigendum to: 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC.

McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., Chioncel, O. D., et al. (2021) · PubMed · doi:10.1093/eurheartj/ehab670 · Cited by 19,618 · see citing works

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw128 · Cited by 11,429 · see citing works

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C.-L., Abiona, O., Graham, B. S., & McLellan, J. S. (2020) · Science · doi:10.1126/science.abb2507 · Cited by 8,897 · see citing works

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

Xu, Z., Shi, L., Wang, Y., Zhang, J., Huang, L., Zhang, C., Liu, S., Zhao, P., Liu, H., Zhu, L., et al. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30076-x · Cited by 8,545 · see citing works

Angiotensin-neprilysin inhibition versus enalapril in heart failure

McMurray, J. J. V., Packer, M., Desai, A. S., Gong, J., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1409077 · Cited by 6,957 · see citing works

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis

Hamming, I., Timens, W., Bulthuis, M., Lely, A., Navis, G., & van Goor, H. (2004) · The Journal of Pathology · doi:10.1002/path.1570 · Cited by 5,676 · see citing works

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

Grasselli, G., Zangrillo, A., Zanella, A., Antonelli, M., Cabrini, L., Castelli, A., Cereda, D., Coluccello, A., Foti, G., Fumagalli, R., et al. (2020) · JAMA · doi:10.1001/jama.2020.5394 · Cited by 5,469 · see citing works

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

Yan, R., Zhang, Y., Li, Y., Xia, L., Guo, Y., & Zhou, Q. (2020) · Science · doi:10.1126/science.abb2762 · Cited by 4,950 · see citing works

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

Ruan, Q., Yang, K., Wang, W., Jiang, L., & Song, J. (2020) · Intensive Care Medicine · doi:10.1007/s00134-020-05991-x · Cited by 4,898 · see citing works

Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China

Shi, S., Qin, M., Shen, B., Cai, Y., Liu, T., Yang, F., Gong, W., Liu, X., Liang, J., Zhao, Q., et al. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.0950 · Cited by 4,349 · see citing works

Cardiovascular implications of fatal outcomes of patients with Coronavirus Disease 2019 (COVID-19)

Guo, T., Fan, Y., Chen, M., Wu, X., Zhang, L., He, T., Wang, H., Wan, J., Wang, X., & Lu, Z. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.1017 · Cited by 4,194 · see citing works

Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy

Onder, G., Rezza, G., & Brusaferro, S. (2020) · JAMA · doi:10.1001/jama.2020.4683 · Cited by 4,171 · see citing works

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., Huan, Y., Yang, P., Zhang, Y., Deng, W., et al. (2005) · Nature Medicine · doi:10.1038/nm1267 · Cited by 3,445 · see citing works

A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9

Donoghue, M., Hsieh, F., Baronas, E., Godbout, K., Gosselin, M. L., Stagliano, N. E., Donovan, M. J., Woolf, B., Robison, K. E., Jeyaseelan, R., et al. (2000) · Circulation Research · doi:10.1161/01.res.87.5.e1 · Cited by 3,084 · see citing works

COVID-19 and the cardiovascular system

Zheng, Y.-Y., Ma, Y.-T., Zhang, J.-Y., & Xie, X. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0360-5 · Cited by 2,970 · see citing works

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

Fang, L., Karakiulakis, G., & Roth, M. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30116-8 · Cited by 2,947 · see citing works

2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension

Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · Journal of Hypertension · doi:10.1097/hjh.0000000000001940 · Cited by 2,885 · see citing works

Time Course of Lung Changes at Chest CT during Recovery from Coronavirus Disease 2019 (COVID-19)

Pan, F., Ye, T., Sun, P., Gui, S., Liang, B., Li, L., Zheng, D., Wang, J., Hesketh, R. L., Yang, L., et al. (2020) · Radiology · doi:10.1148/radiol.2020200370 · Cited by 2,862 · see citing works

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

Xu, H., Zhong, L., Deng, J., Peng, J., Dan, H., Zeng, X., Li, T., & Chen, Q. (2020) · International Journal of Oral Science · doi:10.1038/s41368-020-0074-x · Cited by 2,838 · see citing works

Angiotensin-converting enzyme 2 protects from severe acute lung failure

Imai, Y., Kuba, K., Rao, S., Huan, Y., Guo, F., Guan, B., Yang, P., Sarao, R., Wada, T., Leong-Poi, H., et al. (2005) · Nature · doi:10.1038/nature03712 · Cited by 2,453 · see citing works

Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State

Arentz, M., Yim, E., Klaff, L., Lokhandwala, S., Riedo, F. X., Chong, M., & Lee, M. (2020) · JAMA · doi:10.1001/jama.2020.4326 · Cited by 2,259 · see citing works

High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) Requiring Invasive Mechanical Ventilation

Simonnet, A., Chetboun, M., Poissy, J., Raverdy, V., Noulette, J., Duhamel, A., Labreuche, J., Mathieu, D., Pattou, F. N., Jourdain, M., et al. (2020) · Obesity · doi:10.1002/oby.22831 · Cited by 2,079 · see citing works

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

Liu, Y., Yang, Y., Zhang, C., Huang, F., Wang, F., Yuan, J., Wang, Z., Li, J., Li, J., Feng, C., et al. (2020) · Science China Life Sciences · doi:10.1007/s11427-020-1643-8 · Cited by 2,037 · see citing works

Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)

Inciardi, R. M., Lupi, L., Zaccone, G., Italia, L., Raffo, M., Tomasoni, D., Cani, D., Cerini, M., Farina, D., Gavazzi, E., et al. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.1096 · Cited by 1,860 · see citing works

Angiotensin-(1–7) is an endogenous ligand for the G protein-coupled receptor Mas

Santos, R. A. S., Silva, A. C. S. E., Maric, C., Silva, D. M. R., Machado, R. P., de Buhr, I., Heringer‐Walther, S., Pinheiro, S. V. B., Lopes, M. T., Bäder, M., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432869100 · Cited by 1,805 · see citing works

COVID-19 and cardiovascular disease

Clerkin, K. J., Fried, J. A., Raikhelkar, J., Sayer, G., Griffin, J. M., Masoumi, A., Jain, S. S., Burkhoff, D., Kumaraiah, D., Rabbani, L., et al. (2020) · Circulation · doi:10.1161/circulationaha.120.046941 · Cited by 1,738 · see citing works

Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients

Salehi, S., Abedi, A., Balakrishnan, S., & Gholamrezanezhad, A. (2020) · American Journal of Roentgenology · doi:10.2214/ajr.20.23034 · Cited by 1,600 · see citing works

Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2

Ferrario, C. M., Jessup, J. A., Chappell, M. C., Averill, D. B., Brosnihan, K. B., Tallant, E. A., Diz, D. I., & Gallagher, P. E. (2005) · Circulation · doi:10.1161/circulationaha.104.510461 · Cited by 1,567 · see citing works

Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer

Tian, S., Hu, W., Niu, L., Liu, H., Xu, H., & Xiao, S. (2020) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.02.010 · Cited by 1,414 · see citing works

Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase

Vickers, C., Hales, P., Kaushik, V. K., Dick, L. R., Gavin, J. M., Tang, J., Godbout, K., Parsons, T. F., Baronas, E., Hsieh, F., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200581200 · Cited by 1,406 · see citing works

Obesity in Patients Younger Than 60 Years Is a Risk Factor for COVID-19 Hospital Admission

Lighter, J., Phillips, M., Hochman, S. E., Sterling, S., Johnson, D., François, F., & Stachel, A. G. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa415 · Cited by 1,233 · see citing works

Association of inpatient use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19

Zhang, P., Zhu, L., Cai, J., Lei, F., Qin, J.-J., Xie, J., Liu, Y.-M., Zhao, Y.-C., Huang, X., Lin, L., et al. (2020) · Circulation Research · doi:10.1161/circresaha.120.317134 · Cited by 1,133 · see citing works

SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells

Lukassen, S., Chua, R. L., Trefzer, T. B., Kahn, N. C., Schneider, M. A., Muley, T., Winter, H., Meister, M. A., Veith, C., Boots, A. W., et al. (2020) · The EMBO Journal · doi:10.15252/embj.20105114 · Cited by 1,082 · see citing works

Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19

Mancia, G., Rea, F., Ludergnani, M., Apolone, G., & Corrao, G. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2006923 · Cited by 1,071 · see citing works

Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19

Reynolds, H. R., Adhikari, S., Pulgarin, C., Troxel, A. B., Iturrate, E., Johnson, S. B., Hausvater, A., Newman, J. D., Berger, J. S., Bangalore, S., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2008975 · Cited by 1,058 · see citing works

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

Rockx, B., Kuiken, T., Herfst, S., Bestebroer, T., Lamers, M. M., Oude Munnink, B. B., de Meulder, D., van Amerongen, G., van den Brand, J., Okba, N. M. A., et al. (2020) · Science · doi:10.1126/science.abb7314 · Cited by 901 · see citing works

SARS‐coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS

Oudit, G. Y., Kassiri, Z., Jiang, C., Liu, P. P., Poutanen, S. M., Penninger, J. M., & BUTANY, J. W. (2009) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2009.02153.x · Cited by 896 · see citing works

Clinical Characteristics of Refractory Coronavirus Disease 2019 in Wuhan, China

Mo, P., Xing, Y., Xiao, Y., Deng, L., Zhao, Q., Wang, H., Xiong, Y., Cheng, Z., Gao, S., Liang, K., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa270 · Cited by 856 · see citing works

Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor

Ichiki, T., Labosky, P. A., Shiota, C., Okuyama, S., Imagawa, Y., Fogo, A., Niimura, F., Ichikawa, I., Hogan, B. L. M., & lnagami, T. (1995) · Nature · doi:10.1038/377748a0 · Cited by 855 · see citing works

Obesity Is a Risk Factor for Severe COVID-19 Infection

Sattar, N. A., McInnes, I. B., & McMurray, J. J. V. (2020) · Circulation · doi:10.1161/circulationaha.120.047659 · Cited by 706 · see citing works

Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial

Halliday, B. P., Wassall, R., Lota, A. S., Khalique, Z., Gregson, J., Newsome, S., Jackson, R. W., Rahneva, T., Wage, R., Smith, G. C., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)32484-x · Cited by 657 · see citing works

Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension

Meng, J., Xiao, G., Zhang, J., He, X., Ou, M., Bi, J., Yang, R., Di, W., Wang, Z., Li, Z., et al. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1746200 · Cited by 619 · see citing works

A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome

Khan, A., Benthin, C., Zeno, B. R., Albertson, T. E., Boyd, J. H., Christie, J. D., Hall, R., Poirier, G., Ronco, J. J., Tidswell, M., et al. (2017) · Critical Care · doi:10.1186/s13054-017-1823-x · Cited by 600 · see citing works

Upregulation of Angiotensin-Converting Enzyme 2 After Myocardial Infarction by Blockade of Angiotensin II Receptors

Ishiyama, Y., Gallagher, P. E., Averill, D. B., Tallant, E. A., Brosnihan, K. B., & Ferrario, C. M. (2004) · Hypertension · doi:10.1161/01.hyp.0000124667.34652.1a · Cited by 564 · see citing works

Counter-regulatory renin–angiotensin system in cardiovascular disease

Paz Ocaranza, M., Riquelme, J. A., García, L., Jalil, J. E., Chiong, M., Santos, R. A. S., & Lavandero, S. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0244-8 · Cited by 561 · see citing works

Association of Renin-Angiotensin System Inhibitors With Severity or Risk of Death in Patients With Hypertension Hospitalized for Coronavirus Disease 2019 (COVID-19) Infection in Wuhan, China

Li, J., Wang, X., Chen, J., Zhang, H., & Deng, A. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.1624 · Cited by 537 · see citing works

Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation

Massiéra, F., Bloch-Faure, M., Ceiler, D. L., Murakami, K., Fukamizu, A., Gasc, J., Quignard‐Boulangé, A., Négrel, R., Ailhaud, G. P., Seydoux, J., et al. (2001) · The FASEB Journal · doi:10.1096/fj.01-0457fje · Cited by 505 · see citing works

Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63

Glowacka, I., Bertram, S., Herzog, P., Pfefferle, S., Steffen, I., Muench, M. O., Simmons, G., Hofmann, H., Kuri, T., Weber, F., et al. (2009) · Journal of Virology · doi:10.1128/jvi.01248-09 · Cited by 495 · see citing works

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

Zhong, J., Basu, R., Guo, D., Chow, F. L., Byrns, S., Schuster, M., Loibner, H., Wang, X., Penninger, J. M., Kassiri, Z., et al. (2010) · Circulation · doi:10.1161/circulationaha.110.955369 · Cited by 457 · see citing works

Cardiac Complications in Patients With Community-Acquired Pneumonia

Corrales‐Medina, V., Musher, D. M., Wells, G. A., Chirinos, J. A., Chen, L., & Fine, M. J. (2012) · Circulation · doi:10.1161/circulationaha.111.040766 · Cited by 415 · see citing works

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study

de Abajo, F. J., Rodríguez‐Martín, S., Lerma, V., Mejía-Abril, G. P., Aguilar, M., García-Luque, A., Laredo, L., Laosa, O., Centeno-Soto, G. A., Gálvez, M. A., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31030-8 · Cited by 403 · see citing works

Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections

Zou, Z., Yan, Y., Shu, Y., Gao, R., Sun, Y., Li, X., Ju, X., Liang, Z., Liu, Q., Zhao, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms4594 · Cited by 401 · see citing works

Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19)

Mehta, N., Kalra, A., Nowacki, A. S., Anjewierden, S., Han, Z., Bhat, P., Rubio, A. C., Jacob, M. S., Procop, G. W., Harrington, S. M., et al. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.1855 · Cited by 400 · see citing works

Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality

Fosbøl, E. L., Butt, J. H., Østergaard, L., Andersson, C., Selmer, C., Kragholm, K. H., Schou, M., Phelps, M. D., Gislason, G., Gerds, T. A., et al. (2020) · JAMA · doi:10.1001/jama.2020.11301 · Cited by 378 · see citing works

The renin-angiotensin system: going beyond the classical paradigms

Santos, R. A. S., Oudit, G. Y., Verano‐Braga, T., Canta, G., Steckelings, U. M., & Bäder, M. (2019) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00723.2018 · Cited by 341 · see citing works

Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure

Coulson, L. B., Danser, A. H. J., Poglitsch, M., Touyz, R. M., Burnett, J. C. J., Llorens‐Cortés, C., Ehlers, M. R., & Sturrock, E. D. (2019) · Pharmacological Reviews · doi:10.1124/pr.118.017129 · Cited by 341 · see citing works

Effects of Angiotensin II Receptor Blockers and ACE (Angiotensin-Converting Enzyme) Inhibitors on Virus Infection, Inflammatory Status, and Clinical Outcomes in Patients With COVID-19 and Hypertension

Yang, G., Tan, Z., Zhou, L., Yang, M. H., Peng, L., Liu, J., Cai, J., Yang, R., Han, J., Huang, Y., et al. (2020) · Hypertension · doi:10.1161/hypertensionaha.120.15143 · Cited by 341 · see citing works

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

Jia, H. P., Look, D. C., Tan, P., Shi, L., Hickey, M. A., Gakhar, L., Chappell, M. C., Wohlford-Lenane, C., & McCray, P. B. (2009) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00071.2009 · Cited by 329 · see citing works

Gender and the renin–angiotensin–aldosterone system

Komukai, K., Mochizuki, S., & Yoshimura, M. (2010) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2010.00854.x · Cited by 290 · see citing works

Metabolism of Angiotensin-(1–7) by Angiotensin-Converting Enzyme

Chappell, M. C., Pirro, N. T., Sykes, A., & Ferrario, C. M. (1998) · Hypertension · doi:10.1161/01.hyp.31.1.362 · Cited by 288 · see citing works

Renin–angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: an integrated view in humans

Sarzani, R., Salvi, F., Dessı̀-Fulgheri, P., & RAPPELLI, A. (2008) · Journal of Hypertension · doi:10.1097/hjh.0b013e3282f624a0 · Cited by 284 · see citing works

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury

Yang, P., Gu, H., Zhao, Z., Wang, W., Cao, B., Lai, C., Yang, X., Zhang, L., Duan, Y., Zhang, S., et al. (2014) · Scientific Reports · doi:10.1038/srep07027 · Cited by 283 · see citing works

The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension

Shenoy, V., Ferreira, A. J., Qi, Y., Fraga-Silva, R. A., Díez-Freire, C., Dooies, A., Jun, J. Y., Sriramula, S., Mariappan, N., Pourang, D., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200912-1840oc · Cited by 282 · see citing works

Enalapril Attenuates Downregulation of Angiotensin-Converting Enzyme 2 in the Late Phase of Ventricular Dysfunction in Myocardial Infarcted Rat

Ocaranza, M. P., Godoy, I. E., Jalil, J., Varas‐Godoy, M., Collantes, P., Pinto, M., Román, M., Ramirez, C., Copaja, M., Dı́az-Araya, G., et al. (2006) · Hypertension · doi:10.1161/01.hyp.0000237862.94083.45 · Cited by 273 · see citing works

Angiotensin II Mediates Angiotensin Converting Enzyme Type 2 Internalization and Degradation Through an Angiotensin II Type I Receptor–Dependent Mechanism

Deshotels, M. R., Xia, H., Sriramula, S., Lazartigues, E. D., & Filipeanu, C. M. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.03743 · Cited by 264 · see citing works

Urinary Angiotensin-Converting Enzyme 2 in Hypertensive Patients May Be Increased by Olmesartan, an Angiotensin II Receptor Blocker

Furuhashi, M., Moniwa, N., Mita, T., Fuseya, T., Ishimura, S., Ohno, K., Shibata, S., Tanaka, M., Watanabe, Y. S., Akasaka, H., et al. (2014) · American Journal of Hypertension · doi:10.1093/ajh/hpu086 · Cited by 263 · see citing works

Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus

Gu, H., Xie, Z., Li, T., Zhang, S., Lai, C., Zhu, P., Wang, K., Han, L., Duan, Y., Zhao, Z., et al. (2016) · Scientific Reports · doi:10.1038/srep19840 · Cited by 246 · see citing works

Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis

Caldeira, D., Alarcão, J., Carneiro, A. V., & Costa, J. N. (2012) · BMJ · doi:10.1136/bmj.e4260 · Cited by 244 · see citing works

Tissue-specific nutritional regulation of angiotensinogen in adipose tissue.

Frederich, R. C., Kahn, B. B., Peach, M. J., & Flier, J. S. (1992) · Hypertension · doi:10.1161/01.hyp.19.4.339 · Cited by 244 · see citing works

ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway

Ye, R., & Liu, Z. (2019) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2019.104350 · Cited by 205 · see citing works

Angiotensin Converting Enzyme 2 Contributes to Sex Differences in the Development of Obesity Hypertension in C57BL/6 Mice

Gupte, M., Thatcher, S. E., Boustany, C., Shoemaker, R., Yiannikouris, F. B., Zhang, X., Karounos, M., & Cassis, L. A. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.248559 · Cited by 195 · see citing works

Growth factor expression in aorta of normotensive and hypertensive rats.

Sarzani, R., Brecher, P. I., & Chobanian, A. V. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114029 · Cited by 189 · see citing works

Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Axis Protects against Lung Fibrosis by Inhibiting the MAPK/NF-κB Pathway

Meng, Y., Yu, C., Li, W., Li, T., Luo, W., Huang, S., Wu, P., Cai, S., & Li, X. (2013) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2012-0451oc · Cited by 182 · see citing works

Clinical Relevance and Role of Neuronal AT 1 Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic Hypertension

Xu, J., Sriramula, S., Xia, H., Moreno-Walton, L. A., Culicchia, F., Domenig, O., Poglitsch, M., & Lazartigues, E. D. (2017) · Circulation Research · doi:10.1161/circresaha.116.310509 · Cited by 171 · see citing works

Diminazene Attenuates Pulmonary Hypertension and Improves Angiogenic Progenitor Cell Functions in Experimental Models

Shenoy, V., Gjymishka, A., Jarajapu, Y. P. R., Qi, Y., Afzal, A., Rigatto, K., Ferreira, A. J., Fraga-Silva, R. A., Kearns, P. N., Douglas, J. Y., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201205-0880oc · Cited by 167 · see citing works

The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1–7)-Mas axes in pressure overload-induced cardiac remodeling in male mice

Wang, X., Ye, Y., Gong, H., Wu, J., Yuan, J., Wang, S., Yin, P., Ding, Z., Kang, L., Qiu, J., et al. (2016) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2016.05.012 · Cited by 147 · see citing works

Oral Delivery of Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Bioencapsulated in Plant Cells Attenuates Pulmonary Hypertension

Shenoy, V., Kwon, K., Rathinasabapathy, A., Lin, S., Jin, G., Song, C., Shil, P. K., Nair, A. R., Qi, Y., Li, Q., et al. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.03871 · Cited by 142 · see citing works

Decreased Mortality of COVID-19 With Renin-Angiotensin-Aldosterone System Inhibitors Therapy in Patients With Hypertension

Guo, X., Zhu, Y., & Hong, Y. (2020) · Hypertension · doi:10.1161/hypertensionaha.120.15572 · Cited by 129 · see citing works

Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults

Mackey, K., King, V. J., Gurley, S. B., Kiefer, M., Liederbauer, E., Vela, K., Sonnen, P., & Kansagara, D. L. (2020) · Annals of Internal Medicine · doi:10.7326/m20-1515 · Cited by 129 · see citing works

Angiotensin signalling in pulmonary fibrosis

Uhal, B. D., Li, X., Piasecki, C. C., & Molina‐Molina, M. (2011) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2011.11.019 · Cited by 128 · see citing works

Impact of angiotensin-converting enzyme inhibitors and statins on viral pneumonia

Henry, C. H., Zaizafoun, M., Stock, E. M., Ghamande, S. A., Arroliga, A. C., & White, H. D. (2018) · Baylor University Medical Center Proceedings · doi:10.1080/08998280.2018.1499293 · Cited by 124 · see citing works

Association of Renin-angiotensin-aldosterone System Inhibitors With Coronavirus Disease 2019 (COVID-19)- Related Outcomes in Korea: A Nationwide Population-based Cohort Study

Jung, S., Choi, J. C., You, S., & Kim, W. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa624 · Cited by 113 · see citing works

LOSARTAN PREVENTS SEPSIS-INDUCED ACUTE LUNG INJURY AND DECREASES ACTIVATION OF NUCLEAR FACTORκB AND MITOGEN-ACTIVATED PROTEIN KINASES

Shen, L., Mo, H.-Y., Cai, L., Kong, T., Zheng, W., Ye, J., Qi, J., & Xiao, Z.-L. (2009) · Shock · doi:10.1097/shk.0b013e318189017a · Cited by 107 · see citing works

Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation

Liu, P., Wysocki, J. A., Souma, T., Ye, M., Ramirez, V., Zhou, B., Wilsbacher, L. D., Quaggin, S. E., BATLLE, D. C., & Jin, J. (2018) · Kidney International · doi:10.1016/j.kint.2018.01.029 · Cited by 106 · see citing works

Plasma ACE2 Activity Predicts Mortality in Aortic Stenosis and Is Associated With Severe Myocardial Fibrosis

Ramchand, J., Patel, S. K., Kearney, L. G., Matalanis, G. S., Farouque, O., Srivastava, P., & Burrell, L. M. (2019) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2019.09.005 · Cited by 105 · see citing works

Angiotensin-(1–9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis

Ocaranza, M. P., Moya, J., Barrientos, V., Alzamora, R., Hevia, D., Morales, C., Pinto, M., Escudero, N., Garcı́a, L., Novoa, U., et al. (2014) · Journal of Hypertension · doi:10.1097/hjh.0000000000000094 · Cited by 100 · see citing works

Sex differences in the metabolic effects of the renin-angiotensin system

White, M., Fleeman, R. M., & Arnold, A. C. (2019) · Biology of Sex Differences · doi:10.1186/s13293-019-0247-5 · Cited by 99 · see citing works

Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome

Zambelli, V., Bellani, G., Borsa, R., Pozzi, F., Grassi, A., Scanziani, M., Castiglioni, V., Masson, S., Decio, A., Laffey, J. G., et al. (2015) · Intensive Care Medicine Experimental · doi:10.1186/s40635-015-0044-3 · Cited by 98 · see citing works

A ngiotensin‐(1‐7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation

Magalhães, G. S., Rodrigues‐Machado, M. D. G., Motta‐Santos, D., Silva, A. R., Caliari, M. V., Prata, L. O., Abreu, S. C., Rocco, P. R. M., Barcelos, L. S., Santos, R. A. S., et al. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13057 · Cited by 97 · see citing works

Angiotensin converting enzyme 2 is primarily epithelial and is developmentally regulated in the mouse lung

Wiener, R. S., Cao, Y., Hinds, A., Ramirez, M. I., & Williams, M. C. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21248 · Cited by 86 · see citing works

Alamandine acts via MrgD to induce AMPK/NO activation against ANG II hypertrophy in cardiomyocytes

de Jesus, I. C. G., Scalzo, S., Alves, F., Marques, K., Resende, C. R., Bäder, M., Santos, R. A. S., & Guatimosim, S. (2018) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00153.2017 · Cited by 83 · see citing works

Angiotensin-(1–7) Promotes Resolution of Eosinophilic Inflammation in an Experimental Model of Asthma

Magalhães, G. S., Barroso, L. C., Reis, A. C., Rodrigues‐Machado, M. D. G., Gregório, J. F., Motta‐Santos, D., Oliveira, A. C. D. S., Perez, D., Barcelos, L. S., Teixeira, M. M., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00058 · Cited by 79 · see citing works

Treatment of Pulmonary Hypertension With Angiotensin II Receptor Blocker and Neprilysin Inhibitor Sacubitril/Valsartan

Clements, R., Vang, A., Fernández-Nicolas, A., Kue, N. R., Mancini, T. J., Morrison, A., Mallem, K., McCullough, D. J., & Choudhary, G. (2019) · Circulation Heart Failure · doi:10.1161/circheartfailure.119.005819 · Cited by 79 · see citing works

Cardiac Natriuretic Peptides, Hypertension and Cardiovascular Risk

Sarzani, R., Spannella, F., Giulietti, F., Balietti, P., Cocci, G., & Bordicchia, M. (2017) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-017-0196-1 · Cited by 69 · see citing works

Ramipril in High-Risk Patients With COVID-19

Amat-Santos, I. J., Santos‐Martínez, S., López‐Otero, D., y, L. N.-F., Gutiérrez, E., del Valle-Fernández, R., Muñoz-García, É., Díaz, V. A. J., Regueiro, A., González-Ferreiro, R., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.05.040 · Cited by 66 · see citing works

Increased sFLT‐1 / PlGF ratio in COVID ‐19: A novel link to angiotensin II ‐mediated endothelial dysfunction

Giardini, V., Carrer, A., Casati, M., Contro, E., Vergani, P., & Gambacorti-Passerini, C. B. (2020) · American Journal of Hematology · doi:10.1002/ajh.25882 · Cited by 62 · see citing works

Anti-hypertensive Effects of Diminazene Aceturate: An Angiotensin- Converting Enzyme 2 Activator in Rats

Maria, M. L. A. D., de Araújo, L. D., Fraga-Silva, R. A., Pereira, L. A. S., Ribeiro, H. J., Menezes, G. B., Shenoy, V., Raizada, M. K., & Ferreira, A. J. (2015) · Protein and Peptide Letters · doi:10.2174/0929866522666151013130550 · Cited by 57 · see citing works

Prevalence and Control of Dyslipidemia in Patients Referred for High Blood Pressure: The Disregarded “Double-Trouble” Lipid Profile in Overweight/Obese

Spannella, F., Giulietti, F., Pentima, C. D., & Sarzani, R. (2019) · Advances in Therapy · doi:10.1007/s12325-019-00941-6 · Cited by 46 · see citing works

Effect of Renin-Angiotensin System Blockage in Patients with Acute Respiratory Distress Syndrome: A Retrospective Case Control Study

Kim, J., Choi, S. M., Lee, J., Park, Y. S., Lee, C., Yim, J., Yoo, C., Kim, Y. W., Han, S. K., & Lee, S. (2017) · The Korean Journal of Critical Care Medicine · doi:10.4266/kjccm.2016.00976 · Cited by 43 · see citing works

Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells

Shao, M., Wen, Z., Yang, H., Zhang, C.-Y., Xiong, J., Guan, X., Zhong, W., Jiang, H., Sun, C., Luo, X., et al. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109193 · Cited by 42 · see citing works

Alamandine attenuates arterial remodelling induced by transverse aortic constriction in mice

Souza-Neto, F., Silva, M. M., Santuchi, M. D. C., de Alcântara-Leonídio, T. C., Motta‐Santos, D., Oliveira, A. C. D. S., Melo, M. B., Canta, G., de Souza, L. E., Irigoyen, M. C., et al. (2019) · Clinical Science · doi:10.1042/cs20180547 · Cited by 40 · see citing works

Plasma Aldosterone Is Increased in Class 2 and 3 Obese Essential Hypertensive Patients Despite Drug Treatment

Sarzani, R., Guerra, F., Mancinelli, L., Buglioni, A., Franchi, E., & Dessı̀-Fulgheri, P. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2012.47 · Cited by 37 · see citing works

NT-proBNP and Its Correlation with In-Hospital Mortality in the Very Elderly without an Admission Diagnosis of Heart Failure

Sarzani, R., Spannella, F., Giulietti, F., Fedecostante, M., Giordano, P., Gattafoni, P., Espinosa, E., Busco, F., Piccinini, G., & Dessı̀-Fulgheri, P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153759 · Cited by 37 · see citing works

Characteristics and outcome of viral pneumonia caused by influenza and Middle East respiratory syndrome-coronavirus infections: A 4-year experience from a tertiary care center

Idrees, M., Al-Baadani, A., Elzein, F. E., Alhemyadi, S. A., Khan, O., & Albenmousa, A. (2019) · Annals of Thoracic Medicine · doi:10.4103/atm.atm_179_18 · Cited by 37 · see citing works

Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor

Cha, S. A., Park, B. M., & Kim, S. H. (2018) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2018.22.4.447 · Cited by 36 · see citing works

Autocrine and Paracrine Function of Angiotensin 1-7 in Tissue Repair During Hypertension

Meng, W., Zhao, W., Zhao, T., Liu, C., Chen, Y., Liu, H., & Sun, Y. (2014) · American Journal of Hypertension · doi:10.1093/ajh/hpt270 · Cited by 35 · see citing works

Oral formulation angiotensin-(1-7) therapy attenuates pulmonary and systemic damage in mice with emphysema induced by elastase

Bastos, A. C., Magalhães, G. S., Gregório, J. F., Matos, N. A., Motta-Santos, D., Bezerra, F. S., Santos, R. A. S., Campagnole Santos, M. J., & Rodrigues-Machado, M. G. (2020) · Immunobiology · doi:10.1016/j.imbio.2019.12.002 · Cited by 29 · see citing works

Hypertensive Heart Disease and Obesity: A Complex Interaction Between Hemodynamic and Not Hemodynamic Factors

Sarzani, R., Bordicchia, M., Spannella, F., Dessı̀-Fulgheri, P., & Fedecostante, M. (2014) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-014-0054-3 · Cited by 28 · see citing works

Urinary angiotensin-converting enzyme 2 increases in diabetic nephropathy by angiotensin II type 1 receptor blocker olmesartan

Abe, M., Oikawa, O., Okada, K., & Soma, M. (2014) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.1177/1470320314551443 · Cited by 28 · see citing works

Renin-Angiotensin System Blockers and Statins Are Associated With Lower In-Hospital Mortality in Very Elderly Hypertensives

Spannella, F., Giulietti, F., Balietti, P., Cocci, G., Landi, L., Lombardi, F. E., Borioni, E., Bernardi, B., Rosettani, G., Bordoni, V., et al. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.09.023 · Cited by 25 · see citing works

Severe acute respiratory syndrome coronavirus 2 infection, angiotensin-converting enzyme 2 and treatment with angiotensin-converting enzyme inhibitors or angiotensin II type 1 receptor blockers

Sarzani, R., Giulietti, F., Pentima, C. D., Giordano, P., & Spannella, F. (2020) · European Journal of Preventive Cardiology · doi:10.1177/2047487320918421 · Cited by 11 · see citing works

Plasma renin activity to plasma aldosterone concentration ratio correlates with night-time and pulse pressures in essential hypertensive patients treated with angiotensin-converting enzyme inhibitors/AT1 blockers

Spannella, F., Giulietti, F., Balietti, P., Borioni, E., Lombardi, F. E., Ricci, M., Cocci, G., Landi, L., & Sarzani, R. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001438 · Cited by 10 · see citing works

Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19

Trump, S., Lukassen, S., Anker, M. S., Chua, R. L., Liebig, J., Thürmann, L., Corman, V. M., Binder, M., Loske, J., Klasa, C., et al. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-00796-1 · Cited by 166 · see citing works

Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID‐19

Bousquet, J., Antó, J. M., Czarlewski, W., Haahtela, T., Fonseca, S. C., Iaccarino, G., Blain, H., Vidal, A., Sheikh, A., Akdiş, C. A., et al. (2020) · Allergy · doi:10.1111/all.14549 · Cited by 122 · see citing works

Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies

the ARIA group, Bousquet, J., Cristol, J., Czarlewski, W., Antó, J. M., Martineau, A. R., Haahtela, T., Fonseca, S. C., Iaccarino, G., Blain, H., et al. (2020) · Clinical and Translational Allergy · doi:10.1186/s13601-020-00362-7 · Cited by 80 · see citing works

Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

Habashi, N. M., Camporota, L., Gatto, L. A., & Nieman, G. F. (2021) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00742.2020 · Cited by 73 · see citing works

Acute and chronic exposure to air pollution in relation with incidence, prevalence, severity and mortality of COVID-19: a rapid systematic review

Katoto, P. D., Brand, A., Bakan, B., Obadia, P. M., Kuhangana, T. C., Kayembe‐Kitenge, T., Kitenge, J. P., Nkulu, C. B. L., Vanoirbeek, J. A., Nawrot, T. S., et al. (2021) · Environmental Health · doi:10.1186/s12940-021-00714-1 · Cited by 71 · see citing works

Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19

Pedrosa, M. A., Valenzuela, R., Garrido‐Gil, P., Labandeira, C. M., Navarro, G., Franco, R., Labandeira-García, J. L., & Rodriguez-Perez, A. I. (2021) · Clinical Science · doi:10.1042/cs20201511 · Cited by 66 · see citing works

ACE2 Down-Regulation May Act as a Transient Molecular Disease Causing RAAS Dysregulation and Tissue Damage in the Microcirculatory Environment Among COVID-19 Patients

Ramos, S. G., Rattis, B. A. D. C., Giulia Ottaviani, M., Celes, M. R. N., & Dias, E. P. (2021) · American Journal Of Pathology · doi:10.1016/j.ajpath.2021.04.010 · Cited by 57 · see citing works

Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin–Kallikrein System in Severe COVID-19

Mansour, E., Palma, A. C., Ulaf, R. G., Ribeiro, L. C., Bernardes, A. F., Nunes, T. A., de Agrela, M. V. R., Bombassaro, B., Monfort‐Pires, M., Camargo, R. L., et al. (2021) · Viruses · doi:10.3390/v13020309 · Cited by 54 · see citing works

Downregulation of Membrane-bound Angiotensin Converting Enzyme 2 (ACE2) Receptor has a Pivotal Role in COVID-19 Immunopathology

Vieira, C. C., Nery, L., Martins, L. D. B. U., Jabour, L. G. P. P., Dias, R. F., & Silva, A. C. S. E. (2020) · Current Drug Targets · doi:10.2174/1389450121666201020154033 · Cited by 45 · see citing works

Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation

Turner, A. J., & Nalivaeva, N. N. (2022) · Peptides · doi:10.1016/j.peptides.2022.170766 · Cited by 44 · see citing works

Candesartan could ameliorate the COVID-19 cytokine storm

ELKAHLOUN, A. G., & Saavedra, J. M. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110653 · Cited by 40 · see citing works

Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore

Saavedra, J. M. (2021) · Physiology · doi:10.1152/physiol.00036.2020 · Cited by 37 · see citing works

Spices to Control COVID-19 Symptoms: Yes, but Not Only…

Bousquet, J., Czarlewski, W., Zuberbier, T., Mullol, J., Blain, H., Cristol, J., de la Torre, R., Moing, V. L., Pizarro, N., Bedbrook, A., et al. (2020) · International Archives of Allergy and Immunology · doi:10.1159/000513538 · Cited by 37 · see citing works

Pharmacological mechanisms of traditional Chinese medicine against acute lung injury: From active ingredients to herbal formulae

Liu, Y., Wang, X., Chen, Y., Zhou, L., Wang, Y., Li, L., Wang, Z., & Li, Y. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155562 · Cited by 35 · see citing works

The Renin–Angiotensin–Aldosterone System (RAAS): Beyond Cardiovascular Regulation

Valentini, A., Heilmann, R. M., Kühne, A., Biagini, L., Bellis, D. D., & Rossi, G. (2025) · Veterinary Sciences · doi:10.3390/vetsci12080777 · Cited by 34 · see citing works

The potential role of serum angiotensin-converting enzyme in coronavirus disease 2019

Zhu, Z., Cai, T., Fan, L., Lou, K., Hua, X., Huang, Z., & Gao, G. (2020) · BMC Infectious Diseases · doi:10.1186/s12879-020-05619-x · Cited by 34 · see citing works

Upregulated miR-200c is associated with downregulation of the functional receptor for severe acute respiratory syndrome coronavirus 2 ACE2 in individuals with obesity

Papannarao, J. B., Schwenke, D. O., Manning, P. J., & Katare, R. (2021) · International Journal of Obesity · doi:10.1038/s41366-021-00984-2 · Cited by 31 · see citing works

Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers and outcomes in patients with COVID-19: a systematic review and meta-analysis

Lo, K. B., Bhargav, R., Salacup, G., Pelayo, J., Albano, J., McCullough, P. A., & Rangaswami, J. (2020) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2020.1826308 · Cited by 30 · see citing works

The corona-virus disease 2019 pandemic compromised routine care for hypertension: a survey conducted among excellence centers of the European Society of Hypertension

Weber, T., Januszewicz, A., Rosei, E., Tsioufis, K., Okorie, M., Stergiou, G. S., Volpe, M., Kreutz, R. H., Ábrahám, G., Azizi, M., et al. (2020) · Journal of Hypertension · doi:10.1097/hjh.0000000000002703 · Cited by 30 · see citing works

The effect of estrogen in coronavirus disease 2019

Ma, Q., Hao, Z., & Wang, Y. (2021) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00332.2020 · Cited by 29 · see citing works

Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial

Lobo, S. M., Plantefève, G., Nair, G., Joaquim Cavalcante, A., Franzin de Moraes, N., Nunes, E., Barnum, O., Berdun Stadnik, C. M., Lima, M. P., Lins, M., et al. (2024) · eClinicalMedicine · doi:10.1016/j.eclinm.2023.102383 · Cited by 27 · see citing works

Designed variants of ACE2-Fc that decouple anti-SARS-CoV-2 activities from unwanted cardiovascular effects

Liu, P., Xie, X., Gao, L., & Jin, J. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.10.120 · Cited by 27 · see citing works

Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures

Quijano, A., Díaz-Ruiz, C., López-López, A., Villar‐Cheda, B., Muñoz, A., Rodriguez-Perez, A. I., & Labandeira-García, J. L. (2022) · Antioxidants · doi:10.3390/antiox11020329 · Cited by 26 · see citing works

An Open Label Trial to Assess Safety of Losartan for Treating Worsening Respiratory Illness in COVID-19

Bengtson, C. D., Montgomery, R. N., Nazir, U., Satterwhite, L. G., Kim, M. D., Bahr, N. C., Castro, M., Baumlin, N., & Salathe, M. A. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.630209 · Cited by 22 · see citing works

Possible harm from glucocorticoid drugs misuse in the early phase of SARS-CoV-2 infection: a narrative review of the evidence

Sarzani, R., Spannella, F., Giulietti, F., Pentima, C. D., Giordano, P., & Giacometti, A. (2021) · Internal and Emergency Medicine · doi:10.1007/s11739-021-02860-3 · Cited by 22 · see citing works

Classical and Counter-Regulatory Renin–Angiotensin System: Potential Key Roles in COVID-19 Pathophysiology

Almutlaq, M., Alamro, A. A., Alroqi, F. J., & Barhoumi, T. (2021) · CJC Open · doi:10.1016/j.cjco.2021.04.004 · Cited by 22 · see citing works

Presenting Characteristics, Comorbidities, and Outcomes Among Patients With COVID-19 Hospitalized in Pakistan: Retrospective Observational Study

Akhtar, H., Khalid, S., Rahman, F. U., Umar, M., Ali, S., Afridi, M., Hassan, F., Khader, Y. S., Akhtar, N., Khan, M. M., et al. (2021) · JMIR Public Health and Surveillance · doi:10.2196/32203 · Cited by 20 · see citing works

Drugs Modulating Renin-Angiotensin System in COVID-19 Treatment

Labandeira-García, J. L., Labandeira, C. M., Valenzuela, R., Pedrosa, M. A., Quijano, A., & Rodriguez-Perez, A. I. (2022) · Biomedicines · doi:10.3390/biomedicines10020502 · Cited by 20 · see citing works

Discontinuation of Antihypertensive Medications on the Outcome of Hospitalized Patients With Severe Acute Respiratory Syndrome-Coronavirus 2

Singh, S., Offringa, A. K., Logtenberg, S. J. J., van der Linden, P. D., Janssen, W. M. T., Klein, H., Waanders, F., Şimşek, S., de Jager, C. P. C., Smits, P., et al. (2021) · Hypertension · doi:10.1161/hypertensionaha.121.17328 · Cited by 18 · see citing works

Discontinuing vs continuing ACEIs and ARBs in hospitalized patients with COVID-19 according to disease severity: Insights from the BRACE CORONA trial

Macedo, A. V. S., Silva, P. G. M. D. B. E., de Paula, T. C., Moll-Bernardes, R. J., dos Santos, T. M., Barbosa, L. M., Feldman, A., Arruda, G. D. S., de Albuquerque, D. C., de Sousa, A. S., et al. (2022) · American Heart Journal · doi:10.1016/j.ahj.2022.04.001 · Cited by 18 · see citing works

Hypertension and mortality in SARS-COV-2 infection: A meta-analysis of observational studies after 2 years of pandemic

D’Elia, L., Giaquinto, A., Zarrella, A. F., Rendina, D., Idelson, P. I., Strazzullo, P., & Galletti, F. (2022) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2022.11.018 · Cited by 17 · see citing works

Sacubitril/valsartan alleviates sepsis‐induced acute lung injury via inhibiting GSDMD ‐dependent macrophage pyroptosis in mice

Wang, J., Li, J., Lou, A., Lin, Y. H., Xu, Q., Cui, W., Huang, W., Wang, G., Li, Y., Sun, J., et al. (2022) · FEBS Journal · doi:10.1111/febs.16696 · Cited by 16 · see citing works

Cirrhosis-Associated RAS-Inflammation-Coagulation Axis Anomalies: Parallels to Severe COVID-19

Hartl, L., Jachs, M., Simbrunner, B., Bauer, D. J. M., Semmler, G., Gompelmann, D., Szekeres, T., Quehenberger, P., Trauner, M. A., Mandorfer, M., et al. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11121264 · Cited by 14 · see citing works

Unveiling the Interplay—Vitamin D and ACE-2 Molecular Interactions in Mitigating Complications and Deaths from SARS-CoV-2

Wimalawansa, S. J. (2024) · Biology · doi:10.3390/biology13100831 · Cited by 12 · see citing works

Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters

Briand, F., Sencio, V., Robil, C., Heumel, S., Deruyter, L., Machelart, A., Barthelemy, J., Bogard, G., Hoffmann, E., Infanti, F., et al. (2022) · Viruses · doi:10.3390/v14092067 · Cited by 12 · see citing works

Intrinsic disorder perspective of an interplay between the renin-angiotensin-aldosterone system and SARS-CoV-2

Elrashdy, F., Redwan, E. M., & Uversky, V. N. (2020) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2020.104510 · Cited by 11 · see citing works

NADPH-Oxidase, Rho-Kinase and Autophagy Mediate the (Pro)renin-Induced Pro-Inflammatory Microglial Response and Enhancement of Dopaminergic Neuron Death

López-López, A., Villar‐Cheda, B., Quijano, A., Garrido‐Gil, P., García-Garrote, M., Díaz-Ruiz, C., Muñoz, A., & Labandeira-García, J. L. (2021) · Antioxidants · doi:10.3390/antiox10091340 · Cited by 11 · see citing works

Sex differences in the lung ACE/ACE2 balance in hypertensive rats

Martins, F. L., Tavares, C. A. M., Malagrino, P. A., Rentz, T., Benetti, A., Rios, T. S., Pereira, G. M. D., Caramelli, B., Teixeira, S. K., Krieger, J. E., et al. (2021) · Bioscience Reports · doi:10.1042/bsr20211201 · Cited by 11 · see citing works

Extracellular Vesicles and Their Associated miRNAs as Potential Biomarkers in Intracranial Aneurysm

Li, Y., Wen, J., Liang, D., & Sun, H. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.785314 · Cited by 11 · see citing works

Study protocol for a multicentre, prospective cohort study of the association of angiotensin II type 1 receptor blockers on outcomes of coronavirus infection

Russell, J. A., Marshall, J. C., Slutsky, A. S., Murthy, S., Sweet, D., Lee, T., Singer, J., Patrick, D. M., Du, B., Peng, Z., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-040768 · Cited by 11 · see citing works

Hepatocrinology

Kalra, S., Bhattacharya, S., & Rawal, P. (2021) · Medical Sciences · doi:10.3390/medsci9020039 · Cited by 10 · see citing works

Potential use of renin-angiotensin-aldosterone system inhibitors to reduce COVID-19 severity

Gonçalves, J., Santos, C. D., Fresco, P., & Fernández-Llimós, F. (2023) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2022.02.014 · Cited by 8 · see citing works

Angiotensin II type 2 receptor agonist attenuates LPS-induced acute lung injury through modulating THP-1-derived macrophage reprogramming

Chen, L., Gong, P., Su, Y., Meng, L., Wang, M., Gao, W., & Liu, Q. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02589-0 · Cited by 8 · see citing works

Exploring extracellular vesicles as mediators of clinical disease and vehicles for viral therapeutics: Insights from the COVID-19 pandemic

Craddock, V. D., Cook, C. M., & Dhillon, N. K. (2022) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2022.19 · Cited by 8 · see citing works

Development of a Risk Score for AKI onset in COVID-19 Patients: COV-AKI Score

Palomba, H., Cubos, D. C., Bozza, F. A., Zampieri, F. G., & Romano, T. G. (2023) · BMC Nephrology · doi:10.1186/s12882-023-03095-4 · Cited by 8 · see citing works

Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients

Rodriguez-Perez, A. I., Serrano‐Heras, G., Labandeira, C. M., Camacho-Meño, L., Castro‐Robles, B., Suárez-Quintanilla, J. A., Muñoz, M., Landete, P. P., Guerra, M. J., Segura, T., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1571027 · Cited by 7 · see citing works

The Number of Pills, Rather Than the Type of Renin–Angiotensin System Inhibitor, Predicts Ambulatory Blood Pressure Control in Essential Hypertensives on Triple Therapy: A Real-Life Cross-Sectional Study

Sarzani, R., Giulietti, F., Filipponi, A., Marziali, S., Ristori, L., Buscarini, S., Garbuglia, C., Biondini, S., Allevi, M., & Spannella, F. (2021) · Advances in Therapy · doi:10.1007/s12325-021-01799-3 · Cited by 7 · see citing works

COVID ‐19 pathophysiology and ultrasound imaging: A multiorgan review

Ito, G. N. W., Rodrigues, V. A. C., Hümmelgen, J., Meschino, G. S. P. G., Abou‐Rejaile, G. M., Brenny, I. D., Júnior, C. R. D. C., Artigas, R. C., Munhoz, J. P. D. S., Cardoso, G. C., et al. (2022) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23160 · Cited by 7 · see citing works

Sulforaphane: from death rate heterogeneity in countries to candidate for prevention of severe COVID-19Preprint

Bousquet, J., Antó, J. M., Czarlewski, W., Haahtela, T., Fonseca, S. C., Iaccarino, G., Blain, H., Akdiş, C. A., & Zuberbier, T. (2020) · doi:10.22541/au.159493397.79345039 · Cited by 7 · see citing works

Unveiling the potential therapeutic role of nifuroxazide and liraglutide combination in mitigating LPS-induced acute lung injury through modulation of AT1R/JAK-2/STAT-3 by ACE2/ Ang1‐7/MasR signaling in male albino rats: in vivo and in silico study

Khalifa, A. K., Osman, W. A., Eesa, A. N., Ramadan, N. M., Abdelkader, A., Abdallah, S. S. K., Aboulhoda, B. E., Al‐Shahed, F. A. N., Alghamdi, M. A., El-Rashedy, A. A. E., et al. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115261 · Cited by 6 · see citing works

Angiotensin-converting enzyme 2 in human plasma and lung tissue

Xie, J., Huang, Q., Zhang, Z., Dong, Y., Xu, H., Cao, Y., Sheng, C., Li, Y., Wang, C., Wang, X., et al. (2022) · Blood Pressure · doi:10.1080/08037051.2022.2154745 · Cited by 6 · see citing works

Radiological lung sequelae, functional status and symptoms in older patients 3 and 6 months after hospitalization for COVID-19 pneumonia

Pentima, C. D., Cecchini, S., Spannella, F., Giulietti, F., Allevi, M., Schiavi, P., Carnevali, F., Zoppi, L., Ciociola, M. C., Ventura, F., et al. (2023) · Internal and Emergency Medicine · doi:10.1007/s11739-023-03259-y · Cited by 5 · see citing works

Mechanisms and Potential Roles of Glucose-Lowering Agents in COVID-19: A Review

Berlie, H. D., Kale-Pradhan, P. B., Orzechowski, T., & Jaber, L. A. (2021) · Annals of Pharmacotherapy · doi:10.1177/1060028021999473 · Cited by 5 · see citing works

Inhibition of the postsynaptic density protein 95 on the protective effect of Ang-(1-7)–Mas on cerebral ischaemia injury

Zhao, B., Wang, Z., Liang, X., Wang, X., Lin, K., Yuan, L., Jiang, J., Xu, C., Zhang, D., Sun, Y., et al. (2022) · Stroke and Vascular Neurology · doi:10.1136/svn-2021-001396 · Cited by 5 · see citing works

Expression of SARS-CoV-2 Entry Factors in Human Alveolar Type II Cells in Aging and Emphysema

Lin, C.-R., Bahmed, K., Simborio, H., Hayek, H., Bolla, S., Marchetti, N. T., Criner, G. J., & Kośmider, B. (2021) · Biomedicines · doi:10.3390/biomedicines9070779 · Cited by 5 · see citing works

Regulation of Epithelial Sodium Transport by SARS-CoV-2 Is Closely Related with Fibrinolytic System-Associated Proteins

Wang, T., Zhai, Y., Xue, H., Zhou, W., Ding, Y. P., & Nie, H. (2023) · Biomolecules · doi:10.3390/biom13040578 · Cited by 4 · see citing works

A Testimony of the Surgent SARS-CoV-2 in the Immunological Panorama of the Human Host

Minakshi, R., Jan, A. T., Rahman, S., & Kim, J. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.575404 · Cited by 4 · see citing works

SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis

Quero, K. M., Barreto-Rodríguez, O., Mendez-Rodriguez, V., Sánchez-Monciváis, A., Buendía-Roldán, I., & Chávez‐Galán, L. (2021) · Biomolecules and Biomedicine · doi:10.17305/bjbms.2020.5400 · Cited by 4 · see citing works

The Identikit of Patient at Risk for Severe COVID-19 and Death: The Dysregulation of Renin-Angiotensin System as the Common Theme

Sarzani, R., Allevi, M., Giulietti, F., di Pentima, C., Re, S., Giordano, P., & Spannella, F. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10245883 · Cited by 4 · see citing works

Renin-Angiotensin-System Inhibitors Are Associated With Lower In-hospital Mortality in COVID-19 Patients Aged 80 and Older

Spannella, F., Giulietti, F., Pentima, C. D., Allevi, M., Bordoni, V., Filipponi, A., Falzetti, S., Garbuglia, C., Scorcella, S., Giordano, P., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.916509 · Cited by 3 · see citing works

Hyperoxia‐induced airflow restriction and Renin‐Angiotensin System expression in a bronchopulmonary dysplasia mouse model

Dowell, J. C., Bice, Z., Yan, K., & Konduri, G. G. (2024) · Physiological Reports · doi:10.14814/phy2.15895 · Cited by 3 · see citing works

Lines of Treatment of COVID-19 Infection

ElGoly, A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-90595-4.00002-9 · Cited by 3 · see citing works

Loss of food fermentation in Westernized diet: a risk factor for severe COVID-19?Preprint

Bousquet, J., Antó, J. M., Czarlewski, W., Haahtela, T., Fonseca, S. C., Iaccarino, G., Blain, H., Akdiş, C. A., & Zuberbier, T. (2020) · doi:10.22541/au.159526902.25301228 · Cited by 3 · see citing works

MiR-145–5p reduced ANG II-induced ACE2 shedding and the inflammatory response in alveolar epithelial cells by targeting ADAM17 and inhibiting the AT1R/ADAM17 pathway

Wang, X., Ma, J., Lin, D., Bai, Y., Zhang, D., Jia, X., & Gao, J. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176392 · Cited by 2 · see citing works

Revisiting the monocrotaline‐treated rat as a model of inflammatory lung disease: COVID ‐19 and future pandemic threats?

Kris, L. P., Dixon, D., Bihari, S., & Carr, J. M. (2025) · Animal Models and Experimental Medicine · doi:10.1002/ame2.70099 · Cited by 2 · see citing works

A narrative review of non-pharmacological management of SARS-CoV-2 respiratory failure: a call for an evidence based approach

Vashisht, R., Krishnan, S., & Duggal, A. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-4633 · Cited by 2 · see citing works

Molecular and Physiological Aspects of SARS-CoV-2 Infection in Women and Pregnancy

Liu, A., Xavier, J. P. R., Singh, Y., Brucker, S. Y., & Salker, M. S. (2022) · Frontiers in Global Women s Health · doi:10.3389/fgwh.2022.756362 · Cited by 2 · see citing works

Clinical significance and potential mechanism of hsa_circ_0006892 in acute respiratory distress syndrome complicated with pulmonary fibrosis

Zhang, S., Li, R., Long, G., Huang, F., Zhang, Q., Yang, X., Sun, H., Ji, C., & Ye, R.-H. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-10047-0 · Cited by 1 · see citing works

Unraveling the role of the pulmonary renin–angiotensin system in inflammatory lung injury and hypertension

Xu, C., Ying, Z., & Zhu, M. (2025) · Current Opinion in Physiology · doi:10.1016/j.cophys.2025.100876 · Cited by 1 · see citing works

The metabolic-immune interface of obesity in Covid-19: a role for angiotensin ii and inflammatory cytokines

Rodrigues, C. M., Santos, J. D., Garcia, B. C. C., Ottoni, M. H. F., Costa, K. B., Costa, M. L. B., Figueiredo, V. G., Macedo, D., de Oliveira, D. B., Vieira, E. R., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1729494 · Cited by 1 · see citing works

Differential impact of the angiotensin‑converting enzyme‑2 (ACE2 rs4343 G>A) and miR‑196a2 rs11614913 C>T gene alterations in COVID‑19 disease severity and mortality

Mir, R., Mir, R., Alghamdi, M. A. A., Alsayed, B. A., Elfaki, I., bshabshe, A. A. A. A., Farooq, R., Alhujaily, M. M., Alharthi, M. H., Alamri, M. M. S., et al. (2022) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2022.11345 · Cited by 1 · see citing works

Emerging Contributions of Endocrine Pathophysiology in Virus-Related Infectious Disease: Focus on the RAAS in COVID-19 and HIV

Thomas, T. S., & Srinivasa, S. (2023) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-23621-1_4 · Cited by 1 · see citing works

Effect of Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers on In‐Hospital Outcomes Based on Renal Function Among Critically Ill Patients: Findings From the Medical Information Mart for Intensive Care IV Database

Zhang, C., Hou, T., Wang, F., Hao, C., Ning, M., Shen, H., Chen, Y., & Liu, Y. (2023) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.2302 · Cited by 1 · see citing works

Brassicaceae and Viral Diseases

Ross, I. A. (2024) · Springer eBooks · doi:10.1007/978-3-031-63681-3_14 · Cited by 1 · see citing works

Comment on “Respiratory mechanics and gas exchanges in the early course of COVID-19 ARDS: a hypothesis-generating study”

Damiani, E., Carsetti, A., Casarotta, E., Domizi, R., Scorcella, C., Adrario, E., & Donati, A. (2020) · Annals of Intensive Care · doi:10.1186/s13613-020-00765-6 · Cited by 1 · see citing works

The incidence and mortality of COVID-19 related TB disease in Sub-Saharan Africa: A systematic review and meta-analysisPreprint

Tamuzi, J. L., Lulendo, G., Mbuesse, P., & Nyasulu, P. S. (2022) · medRxiv · doi:10.1101/2022.01.11.22269065 · Cited by 1 · see citing works

Kimchi and Asian fermented vegetables: candidates for the partial control of the COVID-19 pandemicPreprint

Bousquet, J., Antó, J. M., Czarlewski, W., Haahtela, T., Fonseca, S. C., Iaccarino, G., Blain, H., Park, H., Sheikh, A., Akdiş, C. A., et al. (2020) · doi:10.22541/au.159593999.91554264

Reply to: The role of continuous spinal anesthesia in covid-19 pandemic

Spannella, F., Giulietti, F., Damiani, E., Castellani, D., Faloia, L., Sarzani, R., & Starnari, R. (2021) · Minerva Anestesiologica · doi:10.23736/s0375-9393.21.15809-2

The Role of Pulmonary Surfactant in COVID-19 Understanding

Ettarhouni, Z. O., & Mezoughi, A. B. (2021) · International Research Journal of Pure and Applied Chemistry · doi:10.9734/irjpac/2021/v22i630413

Call for Papers: “In It for the Long Haul: Understanding the Lasting Impact of COVID-19 on Lung Health and Disease”

Bartlett, N. W., Bastarache, J. A., Kuebler, W. M., & Schmidt, E. P. (2022) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00352.2022

A REVIEW AND UPDATING OF THE KNOWLEDGE OF BIOCHEMICAL MECHANISMS OF PERFORMANCE ACTING SOME SPICES & MEDICINAL HERBALS FROM AYURVEDA PROTOCOL VS COVID-19

Aulesa, C., & Macedo, A. (2022) · International Journal of Research in Ayurveda and Pharmacy · doi:10.7897/2277-4343.130234

ACE2Fc: A Promising Therapy for SARS-Cov2 Infection

Smitha, P. K., Shandil, R. K., Suresh, P., Biswas, K., Rudramurthy, G. R., Naveenkumar, C. N., Bharathkumar, K., Battula, N. P., Chowdhury, S. D., Sinha, S., et al. (2022) · Medical Research Archives · doi:10.18103/mra.v10i12.3322

Vitamin D supplementation and calcium: Many-faced gods or nobody in fighting against Corona Virus Disease 2019

Roohi, A., & Gharagozlou, S. (2024) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2024.05.015

Obesidade e COVID-19: aumento das concentrações plasmáticas de Ang II afetam a gravidade dos pacientes

Rodrigues, C. M. (2024) · doi:10.11606/t.22.2024.tde-08042024-143329

Effect of Sacubitril-Valsartan on Transcriptomic Changes in Lung Tissue of Spontaneously Hypertensive Rats: A Multi-omics Study Based on RNA-Seq Transcriptome Analysis

Lv, Z., Dai, W., Rong, S., & Du, J. (2025) · American Journal of Hypertension · doi:10.1093/ajh/hpaf143

Additional file 1 of Acute and chronic exposure to air pollution in relation with incidence, prevalence, severity and mortality of COVID-19: a rapid systematic review

Katoto, P. D., Brand, A. S., Bakan, B., Obadia, P. M., Carsi Kuhangana, T., Kayembe‐Kitenge, T., Kitenge, J. P., Nkulu, C. B. L., Vanoirbeek, J. A., Nawrot, T. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14398509

The counter-regulatory arm of the renin-angiotensin system and COVID-19: insights from Gitelman's and Bartter's syndromes

Stefanelli, L. F., Gobbi, L., Ravarotto, V., Bertoldi, G., & Calò, L. A. (2022) · Journal of Hypertension · doi:10.1097/hjh.0000000000003090 · Cited by 6 · see citing works

Renin-angiotensin system at the interface of COVID-19 infection

Gul, R., Kim, U., & Alfadda, A. A. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173656 · Cited by 32 · see citing works

The renin–angiotensin system – a therapeutic target in COVID-19?

Sturrock, B. R., Milne, K. M., & Chevassut, T. J. T. (2020) · Clinical Medicine · doi:10.7861/clinmed.2020-0146 · Cited by 22 · see citing works

Renin Angiotensin Aldosterone System Antagonism in 2019 Novel Coronavirus Acute Lung Injury

Ventura, D., Carr, A., Davis, R. D., Silvestry, S., Bogar, L. J., RAVAL, N. Y., Gries, C., Hayes, J. E., Oliveira, E., Sniffen, J. C., et al. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab170 · Cited by 5 · see citing works

Understanding the Renin-Angiotensin System in Coronavirus Disease 2019

Nagarajan, P. (2023) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-23621-1_5