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The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Effects of creatine supplementation and exercise training on fitness in men 55–75 yr old

Eijnde, Bert O., Van Leemputte, Marc, Goris, Marina, Labarque, Valery, Taes, Youri, Verbessem, Patricia, Vanhees, Luc, Ramaekers, Monique, Vanden Eynde, Bart, Van Schuylenbergh, Reinout, Dom, René, Richter, Erik A., Hespel, Peter·2003·Journal of Applied Physiology
DOI 10.1152/japplphysiol.00891.2002
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Abstract

effect of oral creatine supplementation (CR; 5 g/day) in conjunction with exercise training on physical fitness was investigated in men between 55 and 75 yr of age ( n = 46). A double-blind randomized placebo-controlled (PL) trial was performed over a 6-mo period. Furthermore, a subgroup ( n = 20) completed a 1-yr follow-up. The training program consisted of cardiorespiratory endurance training as well as moderate resistance training (2–3 sessions/wk). Endurance capacity was evaluated during a maximal incremental bicycle ergometer test, maximal isometric strength of the knee-extensor muscles was assessed by an isokinetic dynamometer, and body composition was assessed by hydrostatic weighing. Furthermore, in a subgroup (PL: n = 13; CR: n = 12) biopsies were taken from m. vastus lateralis to determine total creatine (TCr) content. In PL, 6 mo of training increased peak oxygen uptake rate (+16%; P < 0.05). Fat-free mass slightly increased (+0.3 kg; P < 0.05), whereas percent body fat slightly decreased (-1.2%; P < 0.05). The training intervention did not significantly change either maximal isometric strength or body weight. The responses were independent of CR. Still, compared with PL, TCr was increased by ∼5% in CR, and this increase was closely correlated with initial muscle creatine content ( r = -0.78; P < 0.05). After a 1-yr follow-up, muscle TCr was not higher in CR than in PL. Furthermore, the other measurements were not affected by CR. It is concluded that long-term creatine intake (5 g/day) in conjunction with exercise training does not beneficially impact physical fitness in men between 55 and 75 yr of age.

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Research works printed but not linked: 31

  1. 10.1053/meta.2001.28159 · DOI
  2. 10.1016/S0140-6736(00)03138-X · DOI
  3. Baladay GJ, Berra KA, Golding LA, Gordon NF, Mahler DA, Myers JN, and Sheldahl LM. ACSM's Guidelines for Exercise Testing and Prescription. Philadelphia, PA: Lippincott Williams & Wilkins, 2000.
  4. 10.1046/j.1365-201X.1998.00427.x · DOI · Paper page
  5. 10.1177/18.9.670 · DOI · Paper page
  6. 10.1023/A:1022439302975 · DOI
  7. 10.1159/000046878 · DOI
  8. Durstine JL and Haskell WL. Effects of exercise training on plasma lipids and lipoproteins. Exerc Sport Sci Rev 22: 477-521, 1994. · DOI · Paper page
  9. 10.1093/jn/122.suppl_3.796 · DOI
  10. 10.1152/jappl.1990.68.1.329 · DOI · Paper page
  11. 10.1152/jappl.1988.64.3.1038 · DOI · Paper page
  12. 10.1016/S0008-6363(95)00062-3 · DOI
  13. 10.1097/00005768-200203000-00023 · DOI · Paper page
  14. 10.1152/ajpendo.1994.266.5.E725 · DOI · Paper page
  15. 10.1139/h2001-045 · DOI
  16. 10.1111/j.1469-7793.2001.0625c.xd · DOI · Paper page
  17. 10.1046/j.1365-201x.1999.00619.x · DOI
  18. 10.1097/00042752-199810000-00006 · DOI
  19. 10.1152/jappl.2000.89.3.1072 · DOI
  20. 10.1093/gerona/56.7.M412 · DOI · Paper page
  21. 10.1056/NEJM199903113401017 · DOI
  22. 10.1056/NEJM200011093431911 · DOI
  23. 10.1139/y91-084 · DOI
  24. 10.1007/s004210050291 · DOI · Paper page
  25. 10.1097/00005768-199908000-00005 · DOI · Paper page
  26. Spina RJ. Cardivascular adaptations to endurance exercise training in older men and women. In: Exercise and Sport Sciences Reviews, edited by Holloszy JO. Philadelphia, PA: Lippincott Williams & Wilkins, 1999, p. 317-332.
  27. 10.1212/WNL.52.4.854 · DOI · Paper page
  28. 10.1097/00005768-200003000-00024 · DOI · Paper page
  29. 10.1123/ijsnem.10.2.144 · DOI · Paper page
  30. 10.1001/archneur.57.7.956 · DOI · Paper page
  31. 10.1212/WNL.54.9.1848 · DOI · Paper page

Cited by

Metadata

Authors
Eijnde, B. O., Van Leemputte, M., Goris, M., Labarque, V., Taes, Y., Verbessem, P., Vanhees, L., Ramaekers, M., Vanden Eynde, B., Van Schuylenbergh, R., Dom, R., Richter, E. A., & Hespel, P.
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
2003-08
Volume
95
Issue
2
Pages
818-828
ISSN
  • 8750-7587
  • 1522-1601
DOI
10.1152/japplphysiol.00891.2002
Cited by
76
References
18
Language
en

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