Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 97

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Content of intramyocellular lipids derived by electron microscopy, biochemical assays, and1H-MR spectroscopy

Howald, Hans, Boesch, Chris, Kreis, Roland, Matter, Sibylle, Billeter, Rudolf, Essen-Gustavsson, Birgitta, Hoppeler, Hans·2002·Journal of Applied Physiology
DOI 10.1152/japplphysiol.01174.2001
Open this paper in CoChat — free account

Abstract

Three different methods to determine intramyocellular lipid (IMCL) contents in human skeletal muscle have been compared.1 H-magnetic resonance spectroscopy (MRS) was evaluated against electron microscopic morphometry and biochemical assays of biopsy samples from m. tibialis anterior of 10 healthy subjects. The results of 1 H-MRS and morphometry were strongly correlated, proving the validity of the 1 H-MRS results for the noninvasive determination of IMCL. Biochemical assays yielded results that did not significantly correlate with the results of the other methods. When IMCL levels obtained from the three methods are expressed in common units, it was found that 1 H-MRS yielded IMCL average levels that were 1.8 times lower than those found by morphometry. Potential reasons for the discrepancy are discussed. It is expected that 1 H-MRS will be suitable to replace invasive techniques for IMCL determination, whenever noninvasiveness is crucial, e.g., for repeated investigations in studies of substrate recruitment and recovery in exercise.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1152/japplphysiol.01174.2001

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 5 references

Research works printed but not linked: 38

  1. 10.1152/ajpendo.1999.276.1.E106 · DOI
  2. 10.1017/S0029665199001147 · DOI
  3. 10.1002/mrm.1910370403 · DOI · Paper page
  4. 10.1148/radiology.204.2.9240527 · DOI
  5. 10.1002/1522-2594(200102)45:2<179::AID-MRM1023>3.0.CO;2-D · DOI
  6. 10.1055/s-2001-12407 · DOI
  7. 10.1016/S0076-6879(69)14061-6 · DOI
  8. 10.1007/s003940070002 · DOI
  9. 10.1152/ajpregu.2001.281.3.R760 · DOI
  10. 10.1113/jphysiol.1977.sp011726 · DOI
  11. Folch J, 1957, J Biol Chem, 226, 497, 10.1016/S0021-9258(18)64849-5 · DOI · Paper page
  12. 10.1139/y92-019 · DOI
  13. 10.1007/BF00588462 · DOI · Paper page
  14. 10.1007/BF00589248 · DOI · Paper page
  15. 10.1152/jappl.1986.60.2.562 · DOI · Paper page
  16. 10.1152/jappl.2001.90.4.1267 · DOI
  17. 10.1055/s-2007-971911 · DOI
  18. 10.1055/s-2007-971932 · DOI · Paper page
  19. 10.1073/pnas.86.12.4489 · DOI
  20. 10.1007/BF00943344 · DOI
  21. 10.1113/jphysiol.1993.sp019823 · DOI · Paper page
  22. 10.1152/ajpendo.1998.275.2.E332 · DOI · Paper page
  23. 10.1002/mrm.1910370202 · DOI
  24. Krssak M, 2000, J Clin Endocrinol Metab, 85, 748
  25. Oberholzer F, 1976, Schweiz Z Sportmed, 2, 71
  26. 10.1007/s11745-000-0647-2 · DOI
  27. 10.1152/jappl.1999.87.6.2068 · DOI
  28. 10.1002/mrm.1910290203 · DOI · Paper page
  29. 10.1152/ajpregu.1982.243.3.R271 · DOI · Paper page
  30. 10.1002/mrm.1910390607 · DOI
  31. 10.1152/jappl.1997.82.4.1185 · DOI
  32. 10.1016/0022-510X(89)90215-3 · DOI
  33. 10.1152/ajpendo.1999.276.5.E977 · DOI · Paper page
  34. Vock R, 1996, J Exp Biol, 199, 1689, 10.1242/jeb.199.8.1689 · DOI
  35. Vock R, 1996, J Exp Biol, 199, 1675, 10.1242/jeb.199.8.1675 · DOI
  36. 10.1152/jappl.1996.81.3.1150 · DOI
  37. 10.1007/978-1-4899-1928-1_14 · DOI
  38. 10.1016/S0005-2736(00)00294-7 · DOI · Paper page

Cited by

Metadata

Authors
Howald, H., Boesch, C., Kreis, R., Matter, S., Billeter, R., Essen-Gustavsson, B., & Hoppeler, H.
Affiliations
  • Departments of Anatomy and
  • Clinical Research (Magnetic Resonance Spectroscopy and Methodology), University of Bern, CH-3000 Bern, Switzerland; and
  • Unit of Comparative Medicine and Physiology, Department of Large Animal Sciences, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
2002-06-01
Volume
92
Issue
6
Pages
2264-2272
ISSN
  • 8750-7587
  • 1522-1601
DOI
10.1152/japplphysiol.01174.2001
Cited by
97
References
5
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.