CoChat
Sign Up
Cited by 380Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorMotor Control and Adaptation

The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.

Influence of Reward Expectation on Behavior-Related Neuronal Activity in Primate Striatum

Hollerman, Jeffrey R., Tremblay, Léon, Schultz, Wolfram·1998·Journal of Neurophysiology
DOI 10.1152/jn.1998.80.2.947
Open this paper in CoChat — free account

Abstract

Hollerman, Jeffrey R., Léon Tremblay, and Wolfram Schultz. Influence of reward expectation on behavior-related neuronal activity in primate striatum. J. Neurophysiol. 80: 947–963, 1998. Rewards constitute important goals for voluntary behavior. This study aimed to investigate how expected rewards influence behavior-related neuronal activity in the anterior striatum. In a delayed go-nogo task, monkeys executed or withheld a reaching movement and obtained liquid or sound as reinforcement. An initial instruction picture indicated the behavioral reaction to be performed and the reinforcer to be obtained after a subsequent trigger stimulus. Movements varied according to the reinforcers predicted by the instructions, suggesting that animals differentially expected the two outcomes. About 250 of nearly 1,500 neurons in anterior parts of caudate nucleus, putamen, and ventral striatum showed typical task-related activations that reflected the expectation of instructions and trigger, and the preparation, initiation, and execution of behavioral reactions. Strikingly, most task-related activations occurred only when liquid reward was delivered at trial end, rather than the reinforcing sound. Activations close to the time of reward showed similar preferences for liquid reward over the reinforcing sound, suggesting a relationship to the expectation or detection of the motivational outcome of the trial rather than to a “correct” or “end-of-trial” signal. By contrast, relatively few activations in the present task occurred irrespective of the type of reinforcement. In conclusion, many of the behavior-related neurons investigated in the anterior striatum were influenced by an upcoming primary liquid reward and did not appear to code behavioral acts in a motivationally neutral manner. Rather, these neurons incorporated information about the expected outcome into their behavior-related activity. The activations influenced by reward several seconds before its occurrence may constitute a neuronal basis for the retrograde effects of rewards on behavioral reactions.

Overview

Integrity signals

Registry

Crossref · 10.1152/jn.1998.80.2.947

Cites

64 of 64 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 3

  1. Hollerman J. R., 1993, Soc. Neurosci. Abstr., 19, 1585
  2. Hollerman J. R., 1994, Soc. Neurosci. Abstr., 20, 780
  3. Tremblay L., 1995, Soc. Neurosci. Abstr., 21, 952

Cited by

Sorted by citations

See all 380

Related

See all

Metadata

Authors
Hollerman, J. R., Tremblay, L., & Schultz, W.
Affiliations
University of Fribourg (CH)
ORCID
Venue
Journal of Neurophysiology
Publisher
American Physiological Society
Published
1998-08-01
Volume
80
Issue
2
Pages
947-963
ISSN
  • 0022-3077 (ISSN-L)
  • 1522-1598
DOI
10.1152/jn.1998.80.2.947
OpenAlex
W1924016629
Cited by
380
References
64
Citations by year
2026: 5 · 2025: 6 · 2024: 8 · 2023: 5 · 2022: 7 · 2021: 7 · 2020: 7 · 2019: 7 · 2018: 14 · 2017: 9 · 2016: 23 · 2015: 24 · 2014: 17 · 2013: 9 · 2012: 18
FWCI
7.30
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Neurophysiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (1f32mh010282-01x1)
  • National Institute of Mental Health (MH-10282)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
Keywords
reward anticipation, caudate nucleus, putamen, ventral striatum, single-unit activity, go/no-go task, reaching movements, motivation
MeSH terms
Animals, Behavior, Animal, Conditioning, Psychological, Corpus Striatum, Electrophysiology, Eye Movements, Macaca fascicularis, Male, Movement, Neurons, Photic Stimulation, Psychomotor Performance, Reward

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review