Cited by 369Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology StudiesMemory and Neural Mechanisms

Responses to reward in monkey dorsal and ventral striatum

Apicella, P., Ljungberg, T., Scarnati, E., Schultz, W.·1991·Experimental Brain Research

Abstract

The sources of input and the behavioral effects of lesions and drug administration suggest that the striatum participates in motivational processes. We investigated the activity of single striatal neurons of monkeys in response to reward delivered for performing in a go-nogo task. A drop of liquid was given each time the animal correctly executed or withheld an arm movement in reaction to a visual stimulus. Of 1593 neurons, 115 showed increased activity in response to delivery of liquid reward in both go and nogo trials. Responding neurons were predominantly located in dorsal and ventromedial parts of anterior putamen, in dorsal and ventral caudate, and in nucleus accumbens. They were twice as frequent in ventral as compared to dorsal striatal areas. Responses occurred at a median latency of 337 ms and lasted for 525 ms, with insignificant differences between dorsal and ventral striatum. Reward responses differed from activity recorded in the face area of posterior putamen which varied synchronously with individual mouth movements. Responses were directly related to delivery of primary liquid reward and not to auditory stimuli associated with it. Most of them also occurred when reward was delivered outside of the task. These results demonstrate that neurons of dorsal and particularly ventral striatum are involved in processing information concerning the attribution of primary reward.

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Crossref · 10.1007/bf00231732

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Authors
Apicella, P., Ljungberg, T., Scarnati, E., & Schultz, W.
Affiliations
University of Fribourg (CH)
Venue
Experimental Brain Research
Published
1991-07
Volume
85
Issue
3
Pages
491-500
ISSN
  • 0014-4819 (ISSN-L)
  • 1432-1106
OpenAlex
W2076506821
Cited by
369
References
35
Citations by year
2026: 4 · 2025: 4 · 2024: 4 · 2023: 3 · 2022: 10 · 2021: 5 · 2020: 4 · 2019: 7 · 2018: 13 · 2017: 10 · 2016: 21 · 2015: 15 · 2014: 12 · 2013: 13 · 2012: 18
FWCI
2.61
Type
journal article
Language
en
Open access
closed
Locations
  • Experimental Brain Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords
reward processing, striatum, dorsal striatum, ventral striatum, single-unit activity, go/no-go task, anterior putamen, caudate nucleus, nucleus accumbens, motivational processes, primary reward, response latency
MeSH terms
Animals, Behavior, Animal, Brain Mapping, Corpus Striatum, Macaca fascicularis, Male, Movement, Reaction Time, Reward

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