Internalization of Exosomes through Receptor-Mediated Endocytosis

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834

Extracellular vesicles: Exosomes, microvesicles, and friends

Raposo, G., & Stoorvogel, W. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201211138 · Cited by 8,099

Molecular Biology of the Cell

Alberts, B., Johnson, A., Lewis, J. H., Morgan, D. O., RAFF, M. C., Roberts, K. J., & Walter, P. (2017) · W.W. Norton eBooks · doi:10.1201/9781315735368 · Cited by 7,937

Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids

Théry, C., Amigorena, S., Raposo, G., & Clayton, A. (2006) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0322s30 · Cited by 5,766

Molecular Cell Biology

Lodish, H. F. (1986) · Cited by 5,650

Tumour exosome integrins determine organotropic metastasis

Hoshino, A., Costa-Silva, B., Shen, T.-L., Rodrigues, G., Hashimoto, A., Tesic Mark, M., Molina, H., Kohsaka, S., Di Giannatale, A., Ceder, S., et al. (2015) · Nature · doi:10.1038/nature15756 · Cited by 5,101

Regulated portals of entry into the cell

Conner, S. D., & Schmid, S. L. (2003) · Nature · doi:10.1038/nature01451 · Cited by 3,959

Extracellular vesicles: biology and emerging therapeutic opportunities

EL Andaloussi, S., Mäger, I., Breakefield, X. O., & Wood, M. J. A. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3978 · Cited by 3,571

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

Melo, S. A., Luecke, L. B., Kahlert, C., Fernandez, A. F., Gammon, S. T., Kaye, J., LeBleu, V. S., Mittendorf, E. A., Weitz, J., Rahbari, N., et al. (2015) · Nature · doi:10.1038/nature14581 · Cited by 2,880

Extracellular Vesicles in Breast Cancer: From Biology and Function to Clinical Diagnosis and Therapeutic Management

Loric, S., Denis, J. A., Desbène, C., Sabbah, M., & Conti, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087208 · Cited by 42

Tumor microenvironment involvement in colorectal cancer progression via Wnt/β-catenin pathway: Providing understanding of the complex mechanisms of chemoresistance

Díaz, M. B. N., Martín, M. J., & Gentili, C. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i26.3027 · Cited by 32

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Xu, X., Yin, F., Guo, M., Gan, G., Lin, G., Wen, C., Wang, J., Song, P., Wang, J., Qi, Z., et al. (2022) · PROTEOMICS · doi:10.1002/pmic.202200204 · Cited by 31

Emerging Potential of Exosomes on Adipogenic Differentiation of Mesenchymal Stem Cells

Zhong, Y., Li, X., Wang, F., Wang, S., Wang, X., Tian, X., Bai, S., Miao, D., & Fan, J. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.649552 · Cited by 30

Mesenchymal Stem Cells and MSCs-Derived Extracellular Vesicles in Infectious Diseases: From Basic Research to Clinical Practice

Yudintceva, N. M., Mikhailova, N., Fedorov, V., Samochernykh, K. A., Vinogradova, T. I., Muraviov, A. N., & Shevtsov, M. A. (2022) · Bioengineering · doi:10.3390/bioengineering9110662 · Cited by 30

Mesenchymal stem cell-derived exosomes: A paradigm shift in clinical therapeutics

Chattopadhyay, S., Rajendran, R. L., Chatterjee, G., Reyaz, D., Prakash, K., Hong, C. M., Ahn, B., ArulJothi, K. N., & Gangadaran, P. (2025) · Experimental Cell Research · doi:10.1016/j.yexcr.2025.114616 · Cited by 30

Substrate stiffness regulates the proliferation and inflammation of chondrocytes and macrophages through exosomes

Lai, Q., Li, B., Chen, L., Zhou, Y., Bao, H., & Li, H. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.12.021 · Cited by 32

Exploiting Manipulated Small Extracellular Vesicles to Subvert Immunosuppression at the Tumor Microenvironment through Mannose Receptor/CD206 Targeting

Fiani, M. L., Barreca, V., Sargiacomo, M., Ferrantelli, F., Manfredi, F., & Federico, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176318 · Cited by 29

High efficiency preparation of monodisperse plasma membrane derived extracellular vesicles for therapeutic applications

Alter, C. L., Detampel, P., Schefer, R. B., Lotter, C., Hauswirth, P., Puligilla, R. D., Weibel, V. J., Schenk, S., Heusermann, W., Schürz, M., et al. (2023) · Communications Biology · doi:10.1038/s42003-023-04859-2 · Cited by 27

Engineered plant extracellular vesicles for autoimmune diseases therapy

Han, R., Wu, Y. Q., Han, Y., Liu, X., Liu, H., & Su, J. (2023) · Nano Research · doi:10.1007/s12274-023-6112-1 · Cited by 29

A Review of the Neuroprotective Properties of Exosomes Derived from Stem Cells and Exosome-Coated Nanoparticles for Treating Neurodegenerative Diseases and Stroke

Yang, Y., Nicol, C. J. B., & Chiang, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083915 · Cited by 34

The role of extracellular DNA (exDNA) in cellular processes

Fernández-Domínguez, I. J., Manzo-Merino, J., Taja‐Chayeb, L., Dueñas‐González, A., Pérez‐Cárdenas, E., & Trejo‐Becerril, C. (2021) · Cancer Biology & Therapy · doi:10.1080/15384047.2021.1890319 · Cited by 28

Kinetics and interaction studies of anti-tetraspanin antibodies and ICAM-1 with extracellular vesicle subpopulations using continuous flow quartz crystal microbalance biosensor

Liangsupree, T., Multia, E., Forssén, P., Fornstedt, T., & Riekkola, M. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114151 · Cited by 27

Lipid Phase Separation in Vesicles Enhances TRAIL-Mediated Cytotoxicity

Vu, T. Q., Peruzzi, J. A., Sant’Anna, L. E., Roth, E. W., & Kamat, N. P. (2022) · Nano Letters · doi:10.1021/acs.nanolett.1c04365 · Cited by 27

Advances in studies of circulating microRNAs: origination, transportation, and distal target regulation

Wu, Q., Li, L., Jia, Y., Xu, T., & Zhou, X. (2022) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-022-00705-y · Cited by 27

Navigating the brain: the role of exosomal shuttles in precision therapeutics

Fatima, S., Qaiser, A., Andleeb, S., Hashmi, A. H., & Manzoor, S. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2023.1324216 · Cited by 27

In vivo Fate of Targeted Drug Delivery Carriers

Zhao, F., Wang, J., Zhang, Y., Hu, J., Li, C., Liu, S., Li, R., & Du, R. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s465959 · Cited by 26

Exosomes in Dermatology: A Comprehensive Review of Current Applications, Clinical Evidence, and Future Directions

Nahm, W. J., Nikas, C., Goldust, M., Horneck, N. C., Cervantes, J. A., Burshtein, J. G., & Tsoukas, M. M. (2025) · International Journal of Dermatology · doi:10.1111/ijd.17903 · Cited by 29

Exosomes in pathogenesis, diagnosis, and treatment of pulmonary fibrosis

Yang, Y., Liu, Y., Chai, Y., Liu, K., Hu, W., Zhao, K., Zhu, Y., Gao, P., Huang, Q., & Zhang, C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.927653 · Cited by 25

MSC-derived exosomes enhance the anticancer activity of drugs in 3D spheroid of breast cancer cells

Jafarpour, S., Ahmadi, S., Mokarian, F., Sharifi, M., Ghobakhloo, S., Yazdi, M., Nedaeinia, R., & Salehi, R. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105375 · Cited by 25

Unveiling the Complex World of Extracellular Vesicles: Novel Characterization Techniques and Manufacturing Considerations

Lai, J. J., Hill, J. J., Huang, C. Y., Lee, G. C., Mai, K. W., Shen, M., & Wang, S. K. (2024) · Chonnam Medical Journal · doi:10.4068/cmj.2024.60.1.1 · Cited by 26

Exosomes in the lung cancer microenvironment: biological functions and potential use as clinical biomarkers

Qi, R., Zhao, Y., Guo, Q., Mi, X., Cheng, M., Hou, W., Zheng, H., & Hua, B. (2021) · Cancer Cell International · doi:10.1186/s12935-021-01990-0 · Cited by 24

Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers

Sagini, K., Buratta, S., Delo, F., Pellegrino, R. M., Giovagnoli, S., Urbanelli, L., & Emiliani, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312922 · Cited by 25

Proteomic characterization of Opisthorchis felineus exosome-like vesicles and their uptake by human cholangiocytes

Pakharukova, M. Y., Savina, E., Ponomarev, D. V., Губанова, Н. В., Zaparina, O. G., Zakirova, E. G., Cheng, G., Tikhonova, O. V., & Mordvinov, V. A. (2023) · Journal of Proteomics · doi:10.1016/j.jprot.2023.104927 · Cited by 25

Stem Cell-Derived Nanovesicles: A Novel Cell-Free Therapy for Wound Healing

Huang, J., Zhang, J., Xiong, J., Sun, S., Xia, J., Yang, L., & Liang, Y. (2021) · Stem Cells International · doi:10.1155/2021/1285087 · Cited by 24

Copper/Tin Nanocomposites‐Loaded Exosomes Induce Apoptosis and Cell Cycle Arrest at G0/G1 Phase in Skin Cancer Cell Line

Abdrabou, A., Kishta, M. S., Yakout, S. M., Youssef, A. M., Abdallah, A. N., & Ahmed, H. H. (2024) · Chemistry & Biodiversity · doi:10.1002/cbdv.202400486 · Cited by 23

Targeting phagocytosis checkpoints for cancer immunotherapy

Veillette, A., Li, J., Galindo, C. C., Davidson, D., & Tang, Z.-H. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-025-00893-w · Cited by 26

Characterization of Urine Stem Cell-Derived Extracellular Vesicles Reveals B Cell Stimulating Cargo

Zidan, A. A., Al‐Hawwas, M., Perkins, G. B., Mourad, G. M., Stapledon, C. J. M., Bobrovskaya, L., Zhou, X., & Hurtado, P. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22010459 · Cited by 24

Urinary Extracellular Vesicles for Diabetic Kidney Disease Diagnosis

Saenz‐Pipaon, G., Andueza, S. E., Orbe, J., & Roncal, C. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10102046 · Cited by 24

MicroRNAs: Their Role in Metabolism, Tumor Microenvironment, and Therapeutic Implications in Head and Neck Squamous Cell Carcinoma

Shiah, S., Chou, S.-T., & Chang, J. (2021) · Cancers · doi:10.3390/cancers13225604 · Cited by 26

Aptamer-Assisted Traceless Isolation of PD-L1-Positive Small Extracellular Vesicles for Dissecting Their Subpopulation Signature and Function

Xu, R., Yu, Z., Liu, X.-C., Xie, Q., Wu, M. Y., & Chen, G. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c03725 · Cited by 24

Engineered stem cells targeting multiple cell surface receptors in tumors

Kavari, S. L., & Shah, K. (2019) · Stem Cells · doi:10.1002/stem.3069 · Cited by 22

Microfluidic Approaches and Methods Enabling Extracellular Vesicle Isolation for Cancer Diagnostics

Singh, P. K. K., Patel, A., Kaffenes, A., Hord, C., Kesterson, D., & Prakash, S. (2022) · Micromachines · doi:10.3390/mi13010139 · Cited by 21

Integrated microfluidic platforms for tumor-derived exosome analysis

Xu, H., & Ye, B. (2022) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2022.116860 · Cited by 21

Signature of miRNAs derived from the circulating exosomes of patients with amyotrophic lateral sclerosis

Cheng, Y., Gu, X., Yang, T., Wei, Q., Cao, B., Zhang, Y., Shang, H., & Chen, Y. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1106497 · Cited by 23

Size-exclusion chromatography combined with DIA-MS enables deep proteome profiling of extracellular vesicles from melanoma plasma and serum

Lattmann, E., Raess, L., Tognetti, M., Gómez, J. M. M., Lapaire, V., Bruderer, R., Reiter, L., Feng, Y., Steinmetz, L. M., & Levesque, M. P. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05137-y · Cited by 21

Colorectal cancer cell exosome and cytoplasmic membrane for homotypic delivery of therapeutic molecules

Jarak, I., Santos, A. I., Pinto, A. H., Domingues, C., da Silva, I. S., Melo, R., Veiga, F., & Figueiras, A. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.123456 · Cited by 20

Proteomic Approach for Searching for Universal, Tissue-Specific, and Line-Specific Markers of Extracellular Vesicles in Lung and Colorectal Adenocarcinoma Cell Lines

Novikova, S. E., Shushkova, N. A., Farafonova, T. E., Tikhonova, O. V., Kamyshinsky, R. A., & Zgoda, V. G. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186601 · Cited by 20

Overcoming Blood-Brain Barrier Resistance: Implications for Extracellular Vesicle-Mediated Drug Brain Delivery

Dardet, J. P., Serrano, N., Andras, I. E., & Toborek, M. J. (2022) · Frontiers in Drug Delivery · doi:10.3389/fddev.2022.855017 · Cited by 22

Differences and Similarities of the Intravenously Administered Lipid Nanoparticles in Three Clinical Trials: Potential Linkage between Lipid Nanoparticles and Extracellular Vesicles

Suzuki, Y., Katsurada, Y., & Hyodo, K. (2023) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c00547 · Cited by 23

Bovine mammary alveolar MAC-T cells afford a tool for studies of bovine milk exosomes in drug delivery

Ogunnaike, M., Wang, H., & Zempleni, J. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.121263 · Cited by 20

Heparan sulfate proteoglycan-mediated internalization of extracellular vesicles ameliorates liver fibrosis by targeting hepatic stellate cells

Li, R., Wang, C., Zhou, M., Liu, Y., Chen, S., Chai, Z., Huang, H., Zhang, K., Han, Z., Hua, G., et al. (2022) · Extracellular Vesicle · doi:10.1016/j.vesic.2022.100018 · Cited by 20

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

Al-Jipouri, A., Eritja, À., & Božić, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010485 · Cited by 23

Application of cell membrane-functionalized biomimetic nanoparticles in the treatment of glioma

Zhang, G., Yao, M., Ma, S., Zhang, K., Wang, Y., Wang, Z., Liang, J., Dai, S., Jin, R., & Guan, F. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb00605k · Cited by 19

A simple scalable extracellular vesicle isolation method using polyethylenimine polymers for use in cellular delivery

Petga, M. A. D., Taylor, C., MacPherson, A., Dhadi, S. R., Rollin, T., Roy, J. W., Ghosh, A., Lewis, S. M., & Ouellette, R. J. (2024) · Extracellular Vesicle · doi:10.1016/j.vesic.2023.100033 · Cited by 18

Talin-2 regulates integrin functions in exosomes

Soe, Z. Y., Prajuabjinda, O., Myint, P. K., Gaowa, A., Kawamoto, E., Park, E. J., & Shimaoka, M. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.03.027 · Cited by 18

Interactions of childhood maltreatment and genetic variations in adult depression: A systematic review

Li, M., Liu, S., D’Arcy, C., Gao, T., & Meng, X. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.06.055 · Cited by 18

Harnessing EV communication to restore antitumor immunity

Massaro, C., Min, W., Pegtel, D. M., & Baglio, S. R. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113838 · Cited by 17

Platelet Membrane: An Outstanding Factor in Cancer Metastasis

Durán-Saenz, N. Z., Serrano-Puente, A., Gallegos-Flores, P. I., Mendoza-Almanza, B., Esparza-Ibarra, E. L., Godina-González, S., Gonzalez-Curiel, I. E., Ayala-Luján, J. L., Hernández-Barrales, M., Cueto-Villalobos, C. F., et al. (2022) · Membranes · doi:10.3390/membranes12020182 · Cited by 17

Engineered exosomes as precision tools for brain-targeted drug delivery and treatment of central nervous system diseases

Jin, Y., Zhang, Y., Song, M., Zhou, J., Zhang, H., & Ding, Y. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100344 · Cited by 17

Circulating microRNAs and Their Role in Multiple Myeloma

Federico, C., Sacco, A., Belotti, A., Ribolla, R., Cancelli, V., Giacomini, A., Ronca, R., Chiarini, M., Imberti, L., Marini, M., et al. (2019) · Non-Coding RNA · doi:10.3390/ncrna5020037 · Cited by 16

Engineering of Extracellular Vesicles Based on Payload Changes for Tissue Regeneration

Park, D. J., & Seo, Y. J. (2021) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-021-00349-w · Cited by 16

Investigation of human adipose stem cell-derived nanoparticles as a biomimetic carrier for intracellular drug delivery

Chakravarti, A. R., Pacelli, S., & Paul, A. (2020) · Nanoscale · doi:10.1039/d0nr06571d · Cited by 16

Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells

Xu, Z., Wang, Y., Sun, M. J., Zhou, Y., Cao, J., Zhang, H., Xuan, X., & Zhou, J. (2023) · Parasites & Vectors · doi:10.1186/s13071-023-05753-w · Cited by 15

Extracellular Microvesicles Modified with Arginine-Rich Peptides for Active Macropinocytosis Induction and Delivery of Therapeutic Molecules

Morimoto, K., Ishitobi, J., Noguchi, K., Kira, R., Kitayama, Y., Goto, Y., Fujiwara, D., Michigami, M., Harada, A., Takatani‐Nakase, T., et al. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c14592 · Cited by 15

Small Differences and Big Changes: The Many Variables of MicroRNA Expression and Function in the Brain

Parkins, E. V., & Groß, C. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.0365-24.2024 · Cited by 15

Vesicular traffic-mediated cell-to-cell signaling at the immune synapse in Ankylosing Spondylitis

Tavasolian, F., Pastrello, C., Ahmed, Z., Jurišica, I., & Inman, R. D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1102405 · Cited by 15

The Role of Exosomes in Pancreatic Ductal Adenocarcinoma Progression and Their Potential as Biomarkers

Hsu, S., Jadhao, M., Liao, W., Chang, W., Lin, I., & Chiu, C. (2023) · Cancers · doi:10.3390/cancers15061776 · Cited by 16

Nanoparticle-Based Targeted Drug Delivery Methods for Heart-Specific Distribution in Cardiovascular Therapy

Tashima, T. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17111365 · Cited by 16

Umbilical cord mesenchymal stem cell-derived exosomes promote wound healing and skin regeneration via the regulation of inflammation and angiogenesis

Yang, Y., Huang, Y., Yang, J., Hu, Z., Wu, S., Yuan, Q., Meng, S., Li, D., Jiang, M., Liao, Y., et al. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2025.1641709 · Cited by 15

Integrated proteomic, phosphoproteomic, and N-glycoproteomic analyses of small extracellular vesicles from C2C12 myoblasts identify specific PTM patterns in ligand-receptor interactions

Chen, X., Song, X., Li, J., Wang, J., Yan, Y., & Yang, F. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01640-8 · Cited by 14

Modulated Cell Internalization Behavior of Icosahedral DNA Framework with Programmable Surface Modification

Huang, K., Yang, Q., Bao, M., Wang, S., Zhao, L., Shi, Q., & Yang, Y. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c04106 · Cited by 14

Extracellular vesicles: General features and usefulness in diagnosis and therapeutic management of colorectal cancer

Mammes, A., Pasquier, J., Mammes, O., Conti, M., Douard, R., & Loric, S. (2021) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v13.i11.1561 · Cited by 16

Enhancing the Endocytosis of Phosphatidylserine-Containing Liposomes through Tim4 by Modulation of Membrane Fluidity

Hirose, M., Ueno, T., Nagumo, H., Sato, Y., & Sakai‐Kato, K. (2021) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.1c00645 · Cited by 14

Heterogeneity and Compositional Diversities of Campylobacter jejuni Outer Membrane Vesicles (OMVs) Drive Multiple Cellular Uptake Processes

Khan, A., Sardar, A., Tarafdar, P. K., & Mallick, A. I. (2023) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.3c00422 · Cited by 14

Engineered multitargeting exosomes carrying miR-323a-3p for CRC therapy

Pang, Y., Chen, X., Xu, B., Zhang, Y., Liang, S., Hu, J., Liu, R., Luo, X., & Wang, Y. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125794 · Cited by 13

Small extracellular vesicles loaded with carboplatin effectively enhance the cytotoxicity of drug-resistant cells from Y79 cells-in vitro

Attem, J., Narayana, R. V. L., Manukonda, R., Kaliki, S., & Vemuganti, G. K. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116403 · Cited by 14

Dissemination of the Flavivirus Subgenomic Replicon Genome and Viral Proteins by Extracellular Vesicles

Ishikawa, T., Narita, K., Matsuyama, K., & Masuda, M. (2024) · Viruses · doi:10.3390/v16040524 · Cited by 13

The effect of macrophages and their exosomes in ischemic heart disease

Wang, M., Li, C., Liu, Y., Jin, Y., Yang, Y. P., Tan, X., & Zhang, C. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1402468 · Cited by 13

The Interplay Between Exosomes and Gut Microbiota in Neuroinflammation: A New Frontier in Alzheimer’s Disease

Uceda, S., Reiriz, M., Echeverry‐Alzate, V., & Beltrán-Velasco, A. I. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26125828 · Cited by 14

Therapeutic strategy for exosome-based bone regeneration to osteoporosis: Challenges and potential solutions

Dayanandan, A. P., Bello, A. B., Arai, Y., Lee, S. J., & Lee, S.-H. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.09.042 · Cited by 18

Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease

Flemming, J. P., Wermuth, P. J., & Mahoney, M. G. (2023) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2023.08.024 · Cited by 15

Cellular-Defined Microenvironmental Internalization of Exosomes

Gonda, A., Moyron, R. B., Kabagwira, J., Vallejos, P. A., & Wall, N. R. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.86020 · Cited by 12

Exploring the ncRNA landscape in exosomes: Insights into wound healing mechanisms and therapeutic applications.

Gowtham, A., & Kaundal, R. K. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.139206 · Cited by 11

Brain-derived extracellular vesicles: A promising avenue for Parkinson’s disease pathogenesis, diagnosis, and treatment

Zhang, S., Li, J., Hu, X., Liu, H., Yu, Q., Kuang, G., Liu, L., Yu, D., Lin, Z., & Xiong, N. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-01262 · Cited by 14

Small milk-derived extracellular vesicles: Suitable vehicles for oral drug delivery?

Seegobin, N., Taub, M., Vignal, C., Waxin, C., Chris, V., Awad, A., Murdan, S., & Basit, A. W. (2025) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2025.114744 · Cited by 11

Extracellular vesicles (EVs): What we know of the mesmerizing roles of these tiny vesicles in hematological malignancies?

Dibavar, M. A., Pourbagheri‐Sigaroodi, A., Asemani, Y., Salari, S., & Bashash, D. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119177 · Cited by 12

Tropism of Extracellular Vesicles and Cell-Derived Nanovesicles to Normal and Cancer Cells: New Perspectives in Tumor-Targeted Nucleic Acid Delivery

Oshchepkova, A. L., Markov, O. V., Evtushenko, E. G., Chernonosov, A. А., Владимировна, К. Е., Morozova, K. N., Матвеева, В. А., Artemyeva, L., Vlassov, V. V., & Аркадьевна, З. М. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13111911 · Cited by 10

Multivalency-Induced Shape Deformation of Nanoscale Lipid Vesicles: Size-Dependent Membrane Bending Effects

Park, H., Sut, T. N., Yoon, B. K., Zhdanov, V. P., Kim, J. W., Cho, N., & Jackman, J. A. (2022) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.2c00090 · Cited by 11

The Current Status and Future Direction of Extracellular Nano-vesicles in the Alleviation of Skin Disorders

Ghorbani, R., Hosseinzadeh, S., Azari, A., Taghipour, N., Soleimani, M., Rahimpour, A., & Abbaszadeh, H. (2023) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x18666230418121053 · Cited by 12

Extracellular vesicles tell all: How vesicle-mediated cellular communication shapes hematopoietic stem cell biology with increasing age

Grenier‐Pleau, I., & Abraham, S. A. (2021) · Experimental Hematology · doi:10.1016/j.exphem.2021.08.004 · Cited by 10

Phospholipids in small extracellular vesicles: emerging regulators of neurodegenerative diseases and cancer

Chang, W., Xiao, D., Fang, X., & Wang, J. (2021) · Cytotherapy · doi:10.1016/j.jcyt.2021.09.013 · Cited by 12

Blood plasma high abundant protein depletion unintentionally carries over 100 proteins

Silva-Costa, L. C., Garcia‐Rosa, S., Smith, B. J., Baldasso, P. A., Steiner, J. H., & Martins‐de‐Souza, D. (2019) · Separation Science Plus · doi:10.1002/sscp.201900057 · Cited by 11

Enhancing Cartilage Repair: Surgical Approaches, Orthobiologics, and the Promise of Exosomes

Singer, J., Knezic, N., Layne, J. E., Gohring, G., Christiansen, J., Rothrauff, B., & Huard, J. (2024) · Life · doi:10.3390/life14091149 · Cited by 14

Genetic tools for investigating the life cycle of extracellular vesicles

Zheng, W., Roudi, S., Zhou, H., Corona, M. L., van Niel, G., Nordin, J. Z., & Andaloussi, S. E. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00286-6 · Cited by 11

The internalization mechanisms and trafficking of the pea albumin in Caco-2 cells

Zhang, W., Zhang, S., Chen, C., Liu, N., Dong, Y., Wang, P., & Ren, F. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.06.149 · Cited by 10

Exosomes, microvesicles, and their friends in solid tumors

Corbeil, D., & Lorico, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816053-4.00003-1 · Cited by 10

Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase

Santos‐Pereira, C., Guedes, J. P., Ferreira, D., Rodrigues, L. R., & Côrte‐Real, M. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.09.120 · Cited by 10

Extracellular Vesicles and Their Interplay with Biological Membranes

Yeo Xian Ping, J., Raj Neupane, Y., & Pastorin, G. (2022) · Physiology · doi:10.5772/intechopen.101297 · Cited by 9

Emerging roles of exosomal circRNAs in non-small cell lung cancer

Yin, H., Shi, J., Li, S., You, Q., Zhu, H., Koo, C., Liu, B., Hou, L., & Wu, C. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06463-w · Cited by 9

Developing bioinspired delivery systems for enhanced tumor penetration of macromolecular drugs

Yang, J. P., Zeng, Z., Liu, Y., Li, Y., & Xu, X. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113845 · Cited by 9

Advances in mammalian, plant, and bacterial-derived extracellular vesicles for cancer therapy

Nie, X., Li, Q., Fatima, H., Wang, Y., Meng, F., Xie, J., & Nie, S. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.168637 · Cited by 9

Mucus-derived exosome-like vesicles from the Spanish slug (Arion vulgaris): taking advantage of invasive pest species in biotechnology

Liegertová, M., Semerádtová, A., Kocholatá, M., Průšová, M., Němcová, L., Štofik, M., Kříženecká, S., Malý, J., & Janoušková, O. (2022) · Scientific Reports · doi:10.1038/s41598-022-26335-3 · Cited by 9

Research progress of exosomes as drug carriers in cancer and inflammation

Feng, Q., Zhang, Y., Fang, Y., Kong, X., He, Z., Ji, J., Yang, X., & Zhai, G. (2022) · Journal of drug targeting · doi:10.1080/1061186x.2022.2162059 · Cited by 9

Methods, Mechanisms, and Application Prospects for Enhancing Extracellular Vesicle Uptake

Xu, Y.-P., Jiang, T., Yang, X., & Chen, Z. (2024) · Current Medical Science · doi:10.1007/s11596-024-2861-7 · Cited by 11

Molecular Docking and Intracellular Translocation of Extracellular Vesicles for Efficient Drug Delivery

Matsuzaka, Y., & Yashiro, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112971 · Cited by 8

Exosomes and breast cancer angiogenesis; Highlights in intercellular communication

Khanicheragh, P., Abbasi‐Malati, Z., Saghebasl, S., Hassanpour, P., Milani, S. Z., Rahbarghazi‬, R., & Hasani, A. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03606-9 · Cited by 12

Research progress on mesenchymal stem cell‑derived exosomes in the treatment of osteoporosis induced by knee osteoarthritis (Review)

Xue, H., Shen, X.-L., Wang, Z., Bi, H., Xu, H., Wu, J., Cui, R., & Liu, M.-W. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5601 · Cited by 11

Fostering “Education”: Do Extracellular Vesicles Exploit Their Own Delivery Code?

Paolillo, M., Comincini, S., & Schinelli, S. (2021) · Cells · doi:10.3390/cells10071741 · Cited by 8

Cutting edge approaches for rapid characterization of airway exosomes

Hough, K. P., & Deshane, J. S. (2020) · Methods · doi:10.1016/j.ymeth.2020.01.003 · Cited by 8

Cellular-Defined Microenvironmental Internalization of Exosomes

Wall, N. R. (2020) · BiblioBoard Library Catalog (Open Research Library)

Exosomes: Mechanisms of Uptake

McKelvey, K. J., Powell, K., Ashton, A. W., Morris, J. M., & McCracken, S. A. (2015) · Journal of Circulating Biomarkers · doi:10.33393/jcb.2015.2057 · Cited by 39

Targeting Endocytosis and Cell Communications in the Tumor Immune Microenvironment

Wu, B., Wang, Q., Shi, X., & Jiang, M. (2022) · Cell Communication and Signaling · doi:10.1186/s12964-022-00968-3 · Cited by 17

Known and unknown: Exosome secretion in tumor microenvironment needs more exploration

Huang, M., Ji, J., Xu, X., Jin, D., Wu, T., Lin, R., Huang, Y., Qian, J., Tan, Z., Jiang, F., et al. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.101175 · Cited by 14

Exosomes in tumor microenvironment influence cancer progression and metastasis

Kahlert, C., & Kalluri, R. (2013) · Journal of Molecular Medicine · doi:10.1007/s00109-013-1020-6 · Cited by 888