Cited by 306Extracellular vesicles in diseaseCellular transport and secretionNanoparticle-Based Drug Delivery

The DOI matches its Crossref record; 147 of the 148 references it cites were found in a registry or an index.

Internalization of Exosomes through Receptor-Mediated Endocytosis

Gonda, Amber, Kabagwira, Janviere, Senthil, Girish N., Wall, Nathan R.·2019·Molecular Cancer Research

Open this paper in CoChat — free account

Abstract

The tumor microenvironment is replete with factors secreted and internalized by surrounding cells. Exosomes are nano-sized, protein-embedded, membrane-bound vesicles that are released in greater quantities from cancer than normal cells and taken up by a variety of cell types. These vesicles contain proteins and genetic material from the cell of origin and in the case of tumor-derived exosomes, oncoproteins and oncogenes. With increasing understanding of the role exosomes play in basic biology, a more clear view of the potential exosomes are seen to have in cancer therapeutics emerges. However, certain essential aspects of exosome function, such as the uptake mechanisms, are still unknown. Various methods of cell–exosome interaction have been proposed, but this review focuses on the protein–protein interactions that facilitate receptor-mediated endocytosis, a broadly used mechanism by a variety of cells.

Integrity signals

Registry

Crossref · 10.1158/1541-7786.mcr-18-0891

Cites

147 of 147 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

RETRACTED: Toward tailored exosomes: The exosomal tetraspanin web contributes to target cell selection
Rana, S., Yue, S., Stadel, D., & Zöller, M. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.06.018 · Cited by 688
Retracted
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834
Extracellular vesicles: Exosomes, microvesicles, and friends
Raposo, G., & Stoorvogel, W. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201211138 · Cited by 8,099
Molecular Biology of the Cell
Alberts, B., Johnson, A., Lewis, J. H., Morgan, D. O., RAFF, M. C., Roberts, K. J., & Walter, P. (2017) · W.W. Norton eBooks · doi:10.1201/9781315735368 · Cited by 7,937
Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
Théry, C., Amigorena, S., Raposo, G., & Clayton, A. (2006) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0322s30 · Cited by 5,766
Molecular Cell Biology
Lodish, H. F. (1986) · Cited by 5,650
Tumour exosome integrins determine organotropic metastasis
Hoshino, A., Costa-Silva, B., Shen, T.-L., Rodrigues, G., Hashimoto, A., Tesic Mark, M., Molina, H., Kohsaka, S., Di Giannatale, A., Ceder, S., et al. (2015) · Nature · doi:10.1038/nature15756 · Cited by 5,101
Regulated portals of entry into the cell
Conner, S. D., & Schmid, S. L. (2003) · Nature · doi:10.1038/nature01451 · Cited by 3,959
Extracellular vesicles: biology and emerging therapeutic opportunities
EL Andaloussi, S., Mäger, I., Breakefield, X. O., & Wood, M. J. A. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3978 · Cited by 3,571
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Melo, S. A., Luecke, L. B., Kahlert, C., Fernandez, A. F., Gammon, S. T., Kaye, J., LeBleu, V. S., Mittendorf, E. A., Weitz, J., Rahbari, N., et al. (2015) · Nature · doi:10.1038/nature14581 · Cited by 2,880

Show all 148 references

Research works printed but not linked: 1

Jia, 2016, Exosomes, microvesicles, and head and neck cancers., Int J Clin Exp Med, 9, 15040

Sorted by citations

Items 201–300 of 306

A Novel Cargo Delivery System‐AnCar‐ExoLaIMTS Ameliorates Arthritis via Specifically Targeting Pro‐Inflammatory Macrophages
Li, S., Wu, Y., Peng, X., Chen, H., Zhang, T., Chen, H., Yang, J., Xie, Y., Qi, H., Xiang, W., et al. (2023) · Advanced Science · doi:10.1002/advs.202306143 · Cited by 7
Efficient cellular transformation via protein delivery through the protrusion-derived extracellular vesicles
Fujioka, T., Nishimura, T., Kawana, H., Hirosawa, K. M., Yamakawa, R., Sapili, H., Oono-Yakura, K., Nakagawa, R., Inoue, T., Nureki, O., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66351-1 · Cited by 8
Metastatic organotropism in peritoneal metastasis: Paget’s hypothesis revisited
Kim, D., Kaushal, D., & Wilson, R. B. (2026) · Clinical and Experimental Medicine · doi:10.1007/s10238-025-01868-9 · Cited by 6
Extracellular vesicles in cancer: golden goose or Trojan horse
Han, T., Hao, Q., Chao, T., Sun, Q., Chen, Y., Gao, B., Guan, L., Ren, W., & Zhou, X. Y. (2024) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjae025 · Cited by 8
hESC-derived extracellular vesicles enriched with MFGE-8 and the GSH redox system act as senotherapeutics for neural stem cells in ischemic stroke
Lee, Y., Lee, J., Kim, J., Cho, S. A., Lee, H.-J., Geum, D., Park, D., & Kim, J. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.01.050 · Cited by 6
Impact of Medium-Sized Extracellular Vesicles on the Transduction Efficiency of Adeno-Associated Viruses in Neuronal and Primary Astrocyte Cell Cultures
Kovács, O. T., Soltész‐Katona, E., Marton, N., Baricza, E., Hunyady, L., Turu, G., & Nagy, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084221 · Cited by 6
Optimization of blood handling for plasma extracellular vesicle isolation
Kabagwira, J., Gonda, A., Vallejos, P. A., Babcock, B. D., Langridge, W. H. R., Senthil, M., & Wall, N. R. (2021) · Journal of Nanoparticle Research · doi:10.1007/s11051-021-05169-6 · Cited by 6
Self-citation
Advances in engineered exosomes towards cancer diagnosis and therapeutics
Tanziela, T., Dong, X., Ye, J., Guo, Z., Jiang, H., Lu, Z., Liu, X., & Wang, X. (2022) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/ac73c9 · Cited by 6
Hyaluronic acid-engineered milk extracellular vesicles to target triple negative breast cancer through CD44
Soares, F. A., Salinas, B., Reis, S., & Nunes, C. (2025) · Pharmaceutical Biology · doi:10.1080/13880209.2025.2511807 · Cited by 5
Macrophages treated with interferons induce different responses in lymphocytes via extracellular vesicles
Giannessi, F., Percario, Z. A., Lombardi, V., Sabatini, A., Sacchi, A., Lisi, V., Battistini, L., Borsellino, G., Affabris, E., & Angelini, D. F. (2024) · iScience · doi:10.1016/j.isci.2024.109960 · Cited by 6
Basic Science and Principles of Stem Cells, Platelet‐Rich Plasma, and Exosomes
Lyles, E., Stegura, C., Broughton, L., Snyder, A., & Schlesinger, T. E. (2024) · Dermatological Reviews · doi:10.1002/der2.258 · Cited by 5
Liposomes - Recent Advances, New Perspectives and Applications
Tyagi, R. K. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.102167 · Cited by 5
Automated On-Line Isolation and Fractionation Method for Subpopulations of Extracellular Vesicles
Wiedmer, S. Κ., Multia, E., Liangsupree, T., & Riekkola, M. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3203-1_8 · Cited by 5
Brassica oleracea L. var. italica Aquaporin Reconstituted Proteoliposomes as Nanosystems for Resveratrol Encapsulation
Yepes‐Molina, L., Teruel, J. A., Johanson, U., & Carvajal, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25041987 · Cited by 5
Regulation of granulosa cell functions through NRP-1 mediated internalization of follicular fluid non-exosomal miR-210
Kumari, S., Chaurasiya, V., Onteru, S. K., & Singh, D. (2021) · Cell and Tissue Research · doi:10.1007/s00441-021-03524-6 · Cited by 5
New Insights on the Mobility of Viral and Host Non-Coding RNAs Reveal Extracellular Vesicles as Intriguing Candidate Antiviral Targets
Wower, I. K., Brandebourg, T. D., & Wower, J. (2020) · Pathogens · doi:10.3390/pathogens9110876 · Cited by 5
Exosome-mediated Antigen Delivery: Unveiling Novel Strategies in Viral Infection ControlPreprint
Safadi, D. E., Krejbich, M., MOKHTARI, A., Lagrave, A., Hirigoyen, U., Lebeau, G., Viranaïcken, W., & Trotot, P. K. (2024) · Preprints.org · doi:10.20944/preprints202401.0044.v1 · Cited by 5
Extracellular vesicles engagement during respiratory viruses infection
Stincarelli, M. A., Arvia, R., & Giannecchini, S. (2023) · Aspects of Molecular Medicine · doi:10.1016/j.amolm.2023.100004 · Cited by 4
Characterization, microRNA profiling, and immunomodulatory role of plasma-derived exosomes from olive flounder (Paralichthys olivaceus) in response to viral hemorrhagic septicemia virus
Nikapitiya, C., Jayathilaka, E. H. T. T., Edirisinghe, S. L., Oh, C., & Zoysa, M. D. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110316 · Cited by 4
SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein
Nakagawa, Y., Kawaguchi, Y., Hirose, H., Hashiguchi, T., Lee, J., Hotta, A., Kawamoto, J., Sasaki, M., Sawa, H., & Futaki, S. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123594 · Cited by 5
Exosomes and microRNAs: Molecular Mediators Linking Obesity, Exercise, and Metabolic Regulation
Joaquim, V. H. A., Pereira, N. P., Caria, A. C. I., Pelozin, B. R. D. A., Fernandes, T. M., & de Oliveira, E. M. (2025) · Current Diabetes Reports · doi:10.1007/s11892-025-01608-z · Cited by 6
90 K increased delivery efficiency of extracellular vesicles through mediating internalization
Zhu, G., Yang, F., Wei, H., Meng, W., Gan, J., Wang, L., He, C., Lu, S., Cao, B., Luo, H., et al. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.12.034 · Cited by 4
Liposomal Nanoparticles: A Viable Nanoscale Drug Carriers for the Treatment of Cancer
Sharma, B., Attri, S., Syal, J., & Sharma, U. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.109581 · Cited by 4
Integrin-Mediated Exosomal Homing to Organs
Park, E. J., & Shimaoka, M. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3203-1_12 · Cited by 4
Molecular Regulation of Lysophosphatidic Acid Receptor 1 Maturation and Desensitization
Zhao, J., Stephens, T., & Zhao, Y. (2021) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-021-00999-6 · Cited by 4
Unlocking the therapeutic potential of tumor-derived small extracellular vesicles in cancer immunotherapy: A multifaceted approach
Ko, H., Kim, C. H., Son, S., Shin, J. M., & Park, J. H. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123733 · Cited by 4
Extracellular vesicles in autoimmune diseases: Mechanistic underpinnings and precision medicine applications
Mo, W., Zhang, Y., Zeng, Y., Zheng, Y., Zhao, S., Wang, X., & Fan, X. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103959 · Cited by 3
Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection
Bernal‐Vicente, B. N., Ponce, I., Ríos‐Castro, E., Moreno‐Castilla, P., & Tovar‐y‐Romo, L. B. (2026) · Journal of Neurochemistry · doi:10.1111/jnc.70350 · Cited by 3
Molecular basis of graphene-induced oxidative stress and mitochondrial signaling in target cells: Consequences for therapeutic window and design of redox-responsive payloads
Patel, G., Satapathy, A., & Satapathy, A. (2026) · TransMed · doi:10.1016/j.tmed.2026.100008 · Cited by 5
Extracellular vesicles as minimally invasive biomarkers and therapeutic platforms in rare neurological diseases
Phan, N. D., Sharma, R. R., Subramanian, S., & Kartha, R. V. (2026) · Frontiers in Aging · doi:10.3389/fragi.2026.1813553 · Cited by 4
Enhanced anticancer effect of cholesteryl doxorubicin liposome-extracellular vesicle hybrid
Choi, J., Park, J.-W., & Doh, K. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.106981 · Cited by 3
Exosomal delivery of AZD5582 to overcome TRAIL resistance as an optimal therapy against triple-negative breast cancer
Zhang, W., Li, Q., Tian, R., Deng, Z., Sun, R., Kuang, X., Peng, J., Xie, B., Huang, C. L., & Yuan, Z. (2025) · Acta Histochemica · doi:10.1016/j.acthis.2025.152270 · Cited by 3
Compromised endothelial progenitor cell exosomal communication with endothelial cells in hypertension ischemia conditions
Chen, S., Polaki, V., Bihl, J. C., & Wang, J. (2022) · Frontiers in Stroke · doi:10.3389/fstro.2022.1015463 · Cited by 3
Physiologic constraints of using exosomes in vivo as systemic delivery vehicles
Lee, D. S., Suh, M., Kang, S. Y., & Hwang, D. W. (2019) · Precision Nanomedicine · doi:10.33218/prnano2(3)070819.1 · Cited by 3
Ancient Origin Properties of Natural Exosomes Contribute to Their Therapeutic Superiority Compared to Artificial NanoparticlesPreprint
Askenase, P. W. (2020) · Preprints.org · doi:10.20944/preprints202006.0200.v1 · Cited by 2
Exosomes in preeclampsia
Vafadar, A., Heidari, Z., Bolbolizadeh, P., Razmjoue, D., Ehtiati, S., & Savardashtaki, A. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120549 · Cited by 2
The ferroptosis-ncRNA-exosome triad: key orchestrators in cancer immunopathogenesis
Jabir, M. S., Ahmed, A. T., Hussen, A., Alkhathami, A. G., Rekha, M. M., Sharma, Y., Rani, P., Prasad, G. V. S., & Ahmed, J. K. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04584-z · Cited by 2
pH-Modulated Nanoarchitectonics for Enhancement of Multivalency-Induced Vesicle Shape Deformation at Receptor-Presenting Lipid Membrane Interfaces
Park, H., Sut, T. N., Ferhan, A. R., Yoon, B. K., Zhdanov, V. P., Cho, N., & Jackman, J. A. (2023) · Langmuir · doi:10.1021/acs.langmuir.3c00777 · Cited by 2
Cancer-Associated Fibroblasts: Heterogeneity and Bimodality in Oncogenesis
Lunina, N. A., Safina, D. R., & Kostrov, S. V. (2023) · Molecular Biology · doi:10.31857/s0026898423050105 · Cited by 2
Vascularized platforms for investigating cell communication via extracellular vesicles
Kim, J., Ro, J., & Cho, Y. (2024) · Biomicrofluidics · doi:10.1063/5.0220840 · Cited by 2
The delivery and transmembrane transport mechanism of SVCV nanovaccine
Zhang, H., Zhang, P., Liu, X., Peng, H.-H., Liu, Q., Wang, J., Zhu, B., Zhou, Y., Sun, Y., & Zhang, C. (2025) · Nano TransMed · doi:10.1016/j.ntm.2025.100077 · Cited by 2
Matrix bound nanovesicles: A great promise for TERM in less than a decade of research
Francesco, D. D., Mantovani, D., Hussey, G. S., & Boccafoschi, F. (2025) · Matrix Biology · doi:10.1016/j.matbio.2025.10.001 · Cited by 4
Cancer diagnosis and analysis devices based on multimolecular crowding
Onoshima, D., & Baba, Y. (2021) · Chemical Communications · doi:10.1039/d1cc05556a · Cited by 2
Perspective Chapter: Exosomes – The Surreptitious Intercellular Messengers in the Body
Soni, N., Jangra, J., Chaudhary, M., Nandi, G., & Bissa, B. (2023) · Physiology · doi:10.5772/intechopen.110779 · Cited by 2
Progress of regulatory RNA in small extracellular vesicles in colorectal cancer
Hu, X., Lu, Y., Zhou, J., Wang, L., Zhang, M., Mao, Y., & Chen, Z. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1225965 · Cited by 2
Dairy Intake Modifies the Level of the Bile Acid Precursor and Its Correlation with Serum Proteins Associated with Cholesterol Clearance in Subjects with Hyperinsulinemia
Mahdavi, A., Trottier, J., Barbier, O., Lebel, M., & Rudkowska, I. (2023) · Nutrients · doi:10.3390/nu15224707 · Cited by 2
Dynamicity of exosomes as immuno-oncological biomarkers in secondary metastasis and cancer therapyPreprint
Roy, S., Das, A., Jahan, N., & Chatterjee, N. (2020) · doi:10.22541/au.159225412.23207274 · Cited by 2
Cancer-Associated Fibroblasts: Heterogeneity and Bimodality in Oncogenesis
Lunina, N. A., Safina, D. R., & Kostrov, S. V. (2023) · Molecular Biology · doi:10.1134/s0026893323050096 · Cited by 1
Impact of Breaking up of Sitting Time on Anti-inflammatory Response Induced by Extracellular Vesicles
Padilha, C. S., Antunes, B. M., Jiménez‐Maldonado, A., St-Pierre, D. H., & Lira, F. S. (2023) · Current Pharmaceutical Design · doi:10.2174/0113816128244442231018070639 · Cited by 1
Exosomes and their roles in major depressive disorder: An overview of the research progress and perspectives
Tian, M., Yi, S., Zhao, L., Li, L., Fang, L., & Ru, Q. (2025) · Pharmacological Research - Reports · doi:10.1016/j.prerep.2025.100035 · Cited by 1
Exploring the Role of Exosomes in Modern Medicine
Dafe, V. N., Hatwar, P. R., Bakal, R. L., & Bindod, H. V. (2025) · International Journal of Pharmaceutical Sciences Review and Research · doi:10.47583/ijpsrr.2025.v85i3.001 · Cited by 1
Therapeutic potentials of mesenchymal stem cell-derived exosomes for major solid malignancies: A narrative systematic review
Wang, X., Pan, Z., Liu, N., Dai, X., Yang, Y. N., Zhang, C., & Xu, Y. (2025) · BioScience Trends · doi:10.5582/bst.2025.01120 · Cited by 1
Gene Editing of a Carcinogenic Liver Fluke Tetraspanin Impairs Parasite Surface Biogenesis and Extracellular Vesicle Uptake by Human Host Cells
Chaiyadet, S., Ittiprasert, W., Smout, M. J., Khowawisetsut, L., Ruangsuwast, A., Brindley, P. J., Loukas, A. C., & Laha, T. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf466 · Cited by 1
Human neural stem cell-derived exosomes promote functional recovery in subarachnoid hemorrhage via bdnf/trkb pathway activation and astrocyte modulation
Zhang, X., Jing, F., Li, J., Bai, Y., Chen, G., Jin, H., Dong, Y., & Liang, G. (2025) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02155-0 · Cited by 1
Exosome membrane-biomimetic nanomedicine targets the pre-metastatic niche via NF-κB inhibition to suppress breast cancer lung metastasis
Tang, R., Mao, C., Hu, C., Liu, W., Bai, J., Wang, Y., Yang, L., & Qi, H. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.102856 · Cited by 1
Exosome-based strategies and immunotherapy for skin cancer: mechanisms, challenges, and future directions
Karimi, H., Seifollahi, N., Yavari, P., Pourrostam, M., Nourbakhsh, S., Rahmati, S., & Rostaminasab, G. (2026) · Medical Oncology · doi:10.1007/s12032-026-03237-2 · Cited by 1
Suppression of exosomal miR-199a-3p, a differentially expressed miRNA in steroid-induced osteonecrosis of the femoral head, promotes cell proliferation, osteogenesis, and angiogenesis while inhibiting dexamethasone-induced apoptosis
Xia, T., Yang, C., Li, X., Chen, T., & Xu, Y. (2026) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2026.1709739 · Cited by 2
Exosomes: Molecular messengers shaping muscle physiology and growth
Afe, A. E., Guo, X., Badshah, F., Li, K., & Zhou, R. (2026) · Tissue and Cell · doi:10.1016/j.tice.2026.103499 · Cited by 2
Germ cell-directed exosomal delivery enables in vivo genetic modification in birds
Choi, H., Jung, K. M., Han, Y., Woo, S. J., & Han, J. Y. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04442-x · Cited by 1
Toxicity Studies of Exosomes and Potential Overcome Approaches
Chandra, P., Ali, Z., Fatma, N., & Sachan, N. (2024) · Springer eBooks · doi:10.1007/978-981-99-8373-5_15 · Cited by 1
Challenges in exosome nanovesicle-based drug delivery and diagnostics
Makwana, V., Desai, N., Rana, D., Benival, D. M., & Vora, L. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-29052-7.00009-x · Cited by 1
Role of exosomes in malignancies
Vodičková, M., Gregorová, J., Žďárská, M., Vlachová, M., & Ševčíková, S. (2020) · Klinicka onkologie · doi:10.14735/amko2020274 · Cited by 1
Identification of subcellular compartments containing disseminated α-synuclein seeds by proteomic analysis
Kasahara, J. (2021) · Institutional Repositories DataBase (IRDB) · doi:10.14988/00028188
打造精品图书提升阅读品位——2004走笔精装书市场
胡志敏 (2004) · 印刷技术
Basic Points of Exosomes and Application for Intracellular Delivery of Therapeutic Molecules
Nakase, I. (2022) · Seibutsu Butsuri · doi:10.2142/biophys.62.13
Compreensão da depressão geriátrica através da biologia de sistemas a partir da análise proteômica de plasma sanguíneo
Costa, L. C. D. S. (2020) · doi:10.47749/t/unicamp.2020.1149188
Imaging and mechanical analysis of single native exosomes by atomic force microscopy
Li, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95360-3.00001-0
Exosomes as mediators of chemical-induced toxicity
Polaka, S., Tekade, M., Vasdev, N., Gupta, T., Pawar, B., Safavi, M., & Tekade, R. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-15840-7.00007-5
Mesenchymal stem cell-derived exosomes as a new possible therapeutic strategy for Parkinson’s disease
Zhang, Z., Kong, J., & An, S. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.1001990
Plant aquaporin reconstituted proteoliposomes as nanosystem for resveratrol encapsulationPreprint
Yepes‐Molina, L., Teruel, J., Johanson, U., & Carvajal, M. (2023) · doi:10.22541/au.169203622.26611689/v1
Gewebe vermitteln mit genetischen Informationen ihren Funktionszustand
Laube, W. (2023) · Springer eBooks · doi:10.1007/978-3-662-67753-7_10
Exosomes from Taenia solium cysticerci impairs PI3K-AKT-mTOR pathway and induces apoptosis in macrophagesPreprint
Rawat, S. S., Keshri, A. K., Arora, N., Kaur, R., & Prasad, A. (2024) · Research Square · doi:10.21203/rs.3.rs-4292286/v1
Endocytic pathways and metabolic fate of colloidal bismuth subcitrate in human renal cells
Yang, Y., Tan, M., Cui, J., Liu, H., Meng, H., Cheng, X., Wang, Y., Wang, Y., & Zhang, L. W. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111256
Nanotechnology in Cancer Therapy
Mishra, N., Shaikh, M. S., Solanki, K. D., Savle, A. M., Coumes, F., & Kadam, Y. (2024) · Advances in chemical and materials engineering book series · doi:10.4018/979-8-3693-6326-3.ch019
Inhibition of cell-cell communication in exosomes
Pasupuleti, V., Renuka, P., & Khatri, D. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-29052-7.00007-6
Exploring extracellular vesicles: Understanding exosomes and beyond
Laxmi, L., Golmei, P., Gugulothu, D. B., Sharma, A., & Kumar, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-29052-7.00002-7
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Protect the Liver Against Ischaemia‒Reperfusion-Induced Injury Via the Let-7i-5p/Faslg AxisPreprint
Gao, Y., He, M. Y., Bian, C., Yu, R., Luo, J.-J., Xiang, Y.-M., Yang, Y.-X., Zeng, Z., & Huang, H. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5071306
Sars-Cov-2 Inhibition Through Mrna Delivery Using Engineered Extracellular Vesicles Displaying the Spike ProteinPreprint
Kawaguchi, Y., Nakagawa, Y., Hirose, H., Hashiguchi, T., Lee, J., Hotta, A., Sasaki, M., Sawa, H., & Futaki, S. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5215105
Exosomes derived from human umbilical cord mesenchymal stem cells attenuate hepatic ischaemia-reperfusion injury via the let-7i-5p/Faslg axis
Gao, Y., He, M. Y., Bian, C., Yu, R., Luo, J.-J., Xiang, Y., Yang, Y.-X., Zeng, Z., & Huang, H. (2025) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i33.108653
Additional file 11 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581967
Additional file 6 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581952
Additional file 10 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581964
Additional file 7 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581955
Additional file 4 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581946
Additional file 12 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581970
Additional file 13 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581973
Additional file 15 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581979
Additional file 1 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581937
Additional file 5 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581949
Additional file 2 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581940
Additional file 3 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581943
Additional file 9 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581961
Additional file 8 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581958
Additional file 14 of Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Xu, Z., Wang, Y., Sun, M., Zhou, Y., Cao, J., 张厚双, Xuan, X., & Zhou, J. (2024) · Figshare · doi:10.6084/m9.figshare.26581976
Exosomes in reproductive biology and medicine
Menon, R., & Kammala, A. K. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-21564-3.00001-5
Mesenchymal stem cell-derived exosome-inspired nanoformulations: a new frontier in targeted cancer therapy
Jadhav, R. S., Koparde, A., Kadam, A. B., & Kanaujia, K. A. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.126929
Engineering Glioma-Cell-Derived Exosomes as Trojan Horse for Precisely Targeted Chemotherapy of Glioblastoma
He, Z., Meng, Z., luan, G., Li, P., Yang, C., Liang, Y., Sun, X., Zhao, L., Wang, G., & Wang, X. (2026) · Biomaterials Research · doi:10.34133/bmr.0365
Engineered Exosomes: Innovative Strategies for Precision Drug Delivery in Parkinson’s Disease
Yuan, X., Wang, C., Yan, J., Wang, J., Li, F., You, Y., & Qi, Z. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05898-6
Cancer-Associated-Fibroblast-Derived Small Extracellular Vesicles (sEVs) in Lung Cancer Immunotherapy Resistance: Mechanistic Insights, Clinical Translations, and Current Challenges
Chen, S., Yan, J., & Peng, X. (2026) · Cells · doi:10.3390/cells15100883
Selaginella doederleinii-derived extracellular vesicle-like particles suppress lung cancer with ferroptosis-associated changes and modulation of the FABP4/PPARG/GPX4 axis
Chen, H., Zhang, J., Wu, L., Wang, Z., Peng, W., He, Z., Tan, X., Yang, R., & Zeng, P. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1829211

Authors: Gonda, A., Kabagwira, J., Senthil, G. N., & Wall, N. R.
Affiliations: Loma Linda University (US)
ORCID: Gonda, Amber
Wall, Nathan R.
Venue: Molecular Cancer Research
Publisher: American Association for Cancer Research (AACR)
Published: 2019-02-01
Volume: 17
Issue: 2
Pages: 337-347
ISSN: 1541-7786 (ISSN-L)
1557-3125
DOI: 10.1158/1541-7786.mcr-18-0891
OpenAlex: W2903083130
Cited by: 296
References: 148
Citations by year: 2026: 24 · 2025: 39 · 2024: 43 · 2023: 50 · 2022: 41 · 2021: 59 · 2020: 26 · 2019: 13
FWCI: 2.40
Type: journal article
Language: en
Open access: closed
Locations: Molecular Cancer Research (publishedVersion)
PubMed (publishedVersion)
Funders: Loma Linda University (LLU) (GCAT2016-2018)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Keywords: exosomes, receptor-mediated endocytosis, exosome uptake, tumor microenvironment, tumor-derived exosomes, oncoprotein, oncogenes, protein-protein interaction, cancer therapeutics, extracellular vesicles
MeSH terms: Endocytosis, Humans, Cell Line, Tumor, Exosomes, Tumor Microenvironment

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Internalization of Exosomes through Receptor-Mediated Endocytosis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks