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Direct Detection and Quantification of Transition Metal Ions in Human Atherosclerotic Plaques: Evidence for the Presence of Elevated Levels of Iron and Copper
Abstract
Objective—The involvement of transition metals in atherosclerosis is controversial. Some epidemiological studies have reported a relationship between iron (Fe) and cardiovascular disease, whereas others have not. Experimental studies have reported elevated levels of iron and copper (Cu) in diseased human arteries but have often used methods that release metal ions from proteins. Methods and Results—In this study, we have used the minimally invasive technique of electron paramagnetic resonance (EPR) spectroscopy and inductively coupled plasma mass spectroscopy (ICPMS) to quantify iron and copper in ex vivo healthy human arteries and carotid lesions. The EPR spectra detected are characteristic of nonheme Fe(III) complexes. Statistically elevated levels of iron were detected in the intima of lesions compared with healthy controls (0.370 versus 0.022 nmol/mg tissue for EPR, 0.525 versus 0.168 nmol/mg tissue by ICPMS,P<0.05 in each cases). Elevated levels of copper were also detected (7.51 versus 2.01 pmol/mg tissue, lesion versus healthy control, respectively,P<0.05). Iron levels did not correlate with the gender or age of the donor, or tissue protein or calcium levels, but cholesterol levels correlated positively with iron accumulation, as measured by EPR. Conclusions—These data support the hypothesis that iron accumulates in human lesions and may contribute to disease progression.
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“The identification of iron accumulation in macrophages as the prime event in the complex pathogenesis of CVUs eventually driving persistent inflammation and tissue damage is also of major relevance for other chronic inflammatory disorders with enhanced iron storage in macrophages, like arteriosclerosis, multiple sclerosis, and other neurodegenerative diseases (79-82).”
From An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice (2011) · cites this paper as [80]
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“Iron and oxidised lipids are both found in atherosclerotic lesions [141,765-777]”
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“in one study (Stadler et al. 2004), the EPR-detectable iron (essentially Fe(III)) in atherosclerotic tissue was seventeen times greater than that in the equivalent healthy tissue”
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Cites
Epstein, F. H., Steinberg, D. I., Parthasarathy, S., Carew, T. E., Khoo, J. C., & Witztum, J. L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904063201407 · Cited by 6,425
Stary, H. C., Chandler, A. B., Dinsmore, R. E., Fuster, V., Glagov, S. K., Insull, W., Rosenfeld, M. E., Schwartz, C. J., Wagner, W. D., & Wissler, R. W. (1995) · Circulation · doi:10.1161/01.cir.92.5.1355 · Cited by 3,506
Davies, M. J., & Thomas, A. C. (1985) · Heart · doi:10.1136/hrt.53.4.363 · Cited by 1,985
Self-citationIntraplaque Hemorrhage and Progression of Coronary Atheroma
Kolodgie, F. D., Gold, H. K., BURKE, A. P., Fowler, D. R., Kruth, H. S., Weber, D. K., Farb, A. A., Guerrero, L. J., Hayase, M., Kutys, R., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035655 · Cited by 1,491
IRON AND THE SEX DIFFERENCE IN HEART DISEASE RISK
Sullivan, J. (1981) · The Lancet · doi:10.1016/s0140-6736(81)92463-6 · Cited by 969
Hazen, S. L., & Heinecke, J. W. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119379 · Cited by 842
Superoxide accelerates DNA damage by elevating free-iron levels
Keyer, K., & Imlay, J. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13635 · Cited by 841
Presence of hypochlorite-modified proteins in human atherosclerotic lesions.
Hazell, L. J., Arnold, L., Flowers, D., Waeg, G., Malle, E., & Stocker, R. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118576 · Cited by 592
Heinecke, J. W., Rosen, H., & Chait, A. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111609 · Cited by 536
Heinecke, J. W. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00173-7 · Cited by 462
Cited by
Sorted by citations
Items 201–300 of 309
Sajnóg, A., Hańć, A., Barałkiewicz, D., Gryszczyńska, B., Majewski, W., & Iskra, M. (2019) · Microchemical Journal · doi:10.1016/j.microc.2019.104090 · Cited by 13
Liu, Q., Jin, J., Xu, C. Y., Li, W., Liang, J., Xu, J., Weng, Z., Zhang, X., Zhang, X., Shao, J., et al. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117942 · Cited by 13
Emerging diagnostic and therapeutic molecular imaging applications in vascular disease
Eraso, L. H., Reilly, M. P., Sehgal, C. M., & Mohler, E. R. (2011) · Vascular Medicine · doi:10.1177/1358863x10392474 · Cited by 13
Wick, M. C., Chemelli-Steingruber, I. E., & Kremser, C. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0338-8_29 · Cited by 12
Wang, J., Garg, N., Duan, X., Liu, Y., Leng, S., Yu, L., Ritman, E. L., Kantor, B., & McCollough, C. H. (2011) · Physics in Medicine and Biology · doi:10.1088/0031-9155/56/22/019 · Cited by 12
Electron Paramagnetic Resonance in A Biomedical Laboratory
Kleschyov, A. L., & Terekhov, M. (2013) · Bioanalysis · doi:10.4155/bio.13.200 · Cited by 12
Application of molecular probes in urinalysis for diseases diagnosis
Feng, Y., Xu, S., Ren, T., Yuan, L., Huan, S., & Zhang, X. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216923 · Cited by 11
Ferroptosis in cardiovascular diseases: molecular mechanisms and a novel therapeutic target
Yu, S., Pang, Z., Fang, H., & Liu, C. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00420-9 · Cited by 13
Pfanzagl, B. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.09.024 · Cited by 11
Microcalcifications in atherosclerotic lesion of apolipoprotein E‐deficient mouse
Debernardi, N., Roijers, R. B., Krams, R., de Crom, R., Mutsaers, P. H. A., & Vusse, G. J. (2010) · International Journal of Experimental Pathology · doi:10.1111/j.1365-2613.2010.00729.x · Cited by 11
Shinde, A. P., Thorave, R. G., Gawhale, S. T., & Malkhede, D. D. (2023) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2023.135060 · Cited by 10
Computational study of Cu2+, Fe2+, Fe3+, Mn2+ and Mn3+ binding sites identification on HSA 4K2C
Wibowo, S., Sumitro, S. B., & Widyarti, S. (2020) · IOP Conference Series Materials Science and Engineering · doi:10.1088/1757-899x/833/1/012052 · Cited by 10
Iron and noncontrast magnetic resonance T2* as a marker of intraplaque iron in human atherosclerosis
Winner, M. W., Sharkey‐Toppen, T., Zhang, X., Pennell, M. L., Simonetti, O. P., Zweier, J. L., Vaccaro, P. S., & Raman, S. V. (2014) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2014.02.006 · Cited by 10
Raman, S., Sankar, D., Ali, A., Uehara, Y., Abe, S., Sambandam, G., & Rao, M. R. (2011) · Clinical and Experimental Hypertension · doi:10.3109/10641963.2010.549259 · Cited by 10
Yang, F., Bao, Q., Wang, Z., Ma, M., Shen, J., Ye, F., & Xie, X. (2020) · BioMed Research International · doi:10.1155/2020/6246041 · Cited by 10
Ironing out macrophages in atherosclerosis
Wang, L., Cai, J., Qiao, T., & Li, K. (2022) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2022196 · Cited by 12
Kałuża, J., Madej, D., & Brzozowska, A. (2013) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2013.03.004 · Cited by 10
Fe3+ ion quantification with reusable bioinspired nanopores
Wang, Y., Hou, Y., Huo, F., & Hou, X. (2024) · Chinese Chemical Letters · doi:10.1016/j.cclet.2024.110428 · Cited by 9
Iron concentrations in atherosclerotic plaque and serum in patients with carotid atherosclerosis
Tasić, N., Tasić, D., Veselinović, M., Jakovljevic, V. L., Djuric, D. M., & Radak, D. J. (2015) · Acta Physiologica Hungarica · doi:10.1556/036.102.2015.2.5 · Cited by 9
Shchelkunova, T. A., Morozov, I. A., Рубцов, П. М., Samokhodskaya, L. M., Kireev, R. A., Andrianova, I. V., Orekhov, A. N., & Smirnov, A. N. (2008) · Biochemistry (Moscow) · doi:10.1134/s0006297908080105 · Cited by 9
Criteria for Carotid Atherosclerotic Plaque Instability
Ignatyev, I. M., Gafurov, M. R., & Кривошеева, Н. В. (2020) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2020.08.145 · Cited by 9
Gao, D., Hu, L., Lv, H., Lian, L., Wang, M., Fan, X., Xie, Y., & Zhang, J. (2023) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001507 · Cited by 9
Iron-catalyzed oxidation of Trp residues in low-density lipoprotein
Chen, H., Chen, C., Chow, L., Chen, C., Lee, Y., Smith, C. V., & Yang, C. (2011) · Biological Chemistry · doi:10.1515/bc.2011.173 · Cited by 9
Oxidative stress and level of-iron indices in coronary heart disease patients.
Ahmad, M., Khan, M. A., & Khan, A. S. (2009) · PubMed · Cited by 9
Calcified atherosclerotic plaque - where exactly is the calcium and what does it contain?
Srinivasan, A., Ramaswamy, V., Kuruvilla, S., Sehgal, P. K., & Balakrishnan, K. R. (2012) · Indian Journal of Thoracic and Cardiovascular Surgery · doi:10.1007/s12055-012-0133-9 · Cited by 9
Talib, J., & Davies, M. J. (2016) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-016-1340-4 · Cited by 9
Self-citationMeroño, T., Brites, F. D., Dauteuille, C., Lhomme, M., Menafra, M., Arteaga, A., Castro, M., Sáez, M. S. C., Ballerga, E. G., Sorroche, P. B., et al. (2014) · Clinical Science · doi:10.1042/cs20140300 · Cited by 9
Nguyen, S. D., & Sok, D. (2004) · Free Radical Research · doi:10.1080/10715760400000943 · Cited by 9
Fan, J., Zhu, T., Tian, X., Wang, M., Li, Z., & Li, W. (2025) · Phytotherapy Research · doi:10.1002/ptr.70027 · Cited by 9
Reversal of atherosclerosis by restoration of vascular copper homeostasis
Zuo, X., Ding, X., Zhang, Y., & Kang, Y. J. (2024) · Experimental Biology and Medicine · doi:10.3389/ebm.2024.10185 · Cited by 8
Nunes, L. L. A., dos Reis, L. M., Osorio, R. C., Machado, H. K. A. G., Moysés, R. M. A., Filho, H. M. L., Elias¹, R. M., Rochitte, C. E., Jorgetti, V., & Custódio, M. R. (2024) · PLoS ONE · doi:10.1371/journal.pone.0306255 · Cited by 8
Homocysteine is Related to Aortic Mineralization in Patients with Ischemic Heart Disease
Peña‐Duque, M. A., González, M. A. B., Valente-Acosta, B., Rodríguez‐Lobato, L. G., Martínez‐Ríos, M. A., Cardoso-Saldaña, G. C., García, R. B., Herrera-Alarcón, V., Linares-López, C., Granados, H. D., et al. (2012) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.10157 · Cited by 8
Ojo, O. O., & Leake, D. S. (2021) · Free Radical Research · doi:10.1080/10715762.2021.1964494 · Cited by 8
Enzyme Activity-Based Optical Probe: Imaging Aminopeptidases N in Vulnerable Plaque and Serum
Shen, J.-X., Guo, R. H., Wang, M., Zhu, H., Jiang, H., Cui, H., & Wang, K. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c04159 · Cited by 7
The Yin and Yang of copper in cardiovascular health and disease
Li, J., Li, Y., Shen, Q., Zhang, Y., Yu, Y., Li, X., & Xiong, Y. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05401-0 · Cited by 6
Iron and atherosclerosis: Lessons learned from rabbits relevant to human disease
Halliwell, B. B., Watt, F., & Minqin, R. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.10.383 · Cited by 7
Anonna, S. N., Ahamed, S. K., Uddin, M. G., Adnan, M. T., Uddin, S., Hussain, M. S., Millat, M. S., Bulbul, L., Bhatta, R., Sarwar, M. S., et al. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e05311 · Cited by 6
Manganese in atherogenesis: Detection, origin, and a role
Lozhkin, A. P., Biktagirov, T., Abdul’yanov, V. A., Gorshkov, O. V., Timonina, E. V., Mamin, G. V., Orlinskiĭ, S. B., Silkin, N. I., Chernov, V. M., Хайруллин, Р. Н., et al. (2011) · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry · doi:10.1134/s1990750811020090 · Cited by 6
Varadarajan, S., Xiao, Z., Das, A., Ash, D., Yadav, S., Matier, C. D., Pezacki, A. T., Chatterjee, B., Antipova, O. A., Vogt, S., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.27.634587 · Cited by 6
Copper and cuproptosis: mechanisms, biology, and roles in disease
Wang, F., Liu, W., Tao, C., Chen, L., Ni, N., Huang, L., Ouyang, Y., Shi, Q., Wu, D., Li, C., et al. (2026) · 中国科学通报:英文版 · doi:10.1016/j.scib.2026.05.007 · Cited by 6
Bile Acid Derived PET‐Based Cation Sensors: Molecular Structure Dependence of their Sensitivity
Maitra, U., & Nath, S. (2009) · Chemistry - An Asian Journal · doi:10.1002/asia.200900026 · Cited by 5
Zvereva, V. V., & Trunova, V. A. (2012) · Journal of Analytical Chemistry · doi:10.1134/s1061934812070064 · Cited by 5
Evaluation of iron, zinc, and copper levels in pterygium tissue
Ortak, H., Demir, H. D., Mendil, D., Söğüt, E., Ardagil, A., & Eğri, M. (2012) · Japanese Journal of Ophthalmology · doi:10.1007/s10384-012-0118-7 · Cited by 5
Arterial Iron Content Is Increased in Patients with High Plasma Ferritin Levels
Madsen, J. B., Pedersen, L., Kidholm, C. L., & Rasmussen, L. M. (2016) · Journal of Vascular Research · doi:10.1159/000452799 · Cited by 5
[Increased iron store and its relationship with cardiovascular disease].
Meroño, T., Sorroche, P. B., & Brites, F. D. (2011) · PubMed · Cited by 5
Manganese in atherogenesis: detection, origin, and role
Lozhkin, A. P., Biktagirov, T., Gorshkiv, O. V., Timonina, E. V., Mamin, G. V., Orlinskiĭ, S. B., Silkin, N. I., Chernov, V. M., Хайруллин, Р. Н., Салахов, М. Х., et al. (2012) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20125803291 · Cited by 5
Spatial correlation of trace elements with morphological features of atherosclerotic plaques
Roijers, R. B., Dutta, R. K., Mutsaers, P. H. A., Gijbels, M. J. J., de Winther, M. P. J., de Goeij, J. J. M., & van der Vusse, G. J. (2005) · Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms · doi:10.1016/j.nimb.2005.01.064 · Cited by 4
Nutraceuticals in immunosenescence
Magrone, T., & Jirillo, E. (2015) · Anti‐ageing nutrients · doi:10.1002/9781118823408.ch5 · Cited by 4
Rosa, N. D. L., Peruzzi, N., Dreier, T., Truong, M., Johansson, U., Kalbfleisch, S., Gonçalves, I., & Bech, M. (2024) · Advanced Intelligent Systems · doi:10.1002/aisy.202400052 · Cited by 4
Kovács, D., Löcsey, L., Laczik, R., Szabó, L. D., Zsom, L., Kabai, K., Fedor, R., Nemes, B., Asztalos, L., & Soltész, P. (2014) · Transplantation Proceedings · doi:10.1016/j.transproceed.2014.05.058 · Cited by 4
Anaemia of Chronic Kidney Disease: What We Know Now
Krishnan, A., Trinder, D., Chua, A. C. G., Chakera, A., Ramm, G. A., & Olynyk, J. K. (2017) · Journal of Renal and Hepatic Disorders · doi:10.15586/jrenhep.2017.5 · Cited by 4
Impact of Heavy Metals Contamination on Human Health
Yadav, M. K., & Pervez, A. (2024) · Environmental science and engineering · doi:10.1007/978-3-031-56642-4_4 · Cited by 3
Essential and Non-Essential Metals and Metalloids and Their Role in Atherosclerosis
Massie, P. L., Garcia, M. A., Decker, A., Liu, R., MazloumiBakhshayesh, M., Kulkarni, D., Justus, M. P., Gallardo, J. F., Abrums, A., Markle, K., et al. (2025) · Cardiovascular Toxicology · doi:10.1007/s12012-025-09998-y · Cited by 3
Manganese as a potential marker of atherogenesis
Lozhkin, A. P., Biktagirov, T., Abdul’yanov, V. A., Voloshin, A. V., Silkin, N. I., Хайруллин, Р. Н., Салахов, М. Х., & Ilinskaya, O. N. (2010) · Doklady Biochemistry and Biophysics · doi:10.1134/s1607672910050091 · Cited by 3
Iron Homeostasis in Tissues Is Affected during Persistent Chlamydia pneumoniae Infection in Mice
Edvinsson, M., Tallkvist, J., Nyström-Rosander, C., & Ilbäck, N. (2017) · BioMed Research International · doi:10.1155/2017/3642301 · Cited by 3
Rashid, I., Brown, B. E., van Reyk, D. M., & Davies, M. J. (2006) · Springer eBooks · doi:10.1007/0-387-36279-3_12 · Cited by 3
Self-citationAnwar, M. C., & Abdel-Halim, K. Y. (2010) · African Journal of Microbiology Research · doi:10.5897/ajmr.9000689 · Cited by 3
Anwar, M. C., & Abdel-Halim, K. Y. (2010) · African Journal of Microbiology Research · doi:10.5897/ajmr.9000109 · Cited by 3
Al-Dejal, A. N., Hakeim, H. K. A., & Al-Hadrawy, S. M. J. (2013) · Al-Kufa University Journal for Biology · Cited by 3
Liu, G., Men, P., Perry, G. L., & Smith, M. A. (2003) · Wiley eBooks · doi:10.1002/9783527610419.ntls0122 · Cited by 3
Localisation of antioxidants and oxidative markers within the atherosclerotic plaque
Flavall, E. A. (2008) · UC Research Repository (University of Canterbury) · doi:10.26021/8695 · Cited by 3
The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application
Ouyang, Y., Jiang, W., Long, X., Mao, P., He, P., & Ouyang, X. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70920 · Cited by 2
Oral Administration of Berberine-Based Carbon Dots Target Ferric Iron to Alleviate Atherosclerosis
Li, X., Wang, Y., Chen, C., Jiang, S., Yu, Z., Gao, Y., Chen, Y., Yang, X., Li, B., Qin, L., et al. (2026) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6c04973 · Cited by 2
Canavesi, E., & Valenti, L. V. C. (2011) · InTech eBooks · doi:10.5772/22735 · Cited by 2
Micro-PIXE with 3.5 MeV protons for the study of low copper concentrations in atherosclerotic artery
Ynsa, M. D., Ripoll-Sau, J., Osipowicz, T., Breese, M. B. H., & Ren, M. (2021) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/j.nimb.2021.04.001 · Cited by 2
Lessons from Experimental-Induced Atherosclerosis: Valuable for the Precision Medicine of Tomorrow
Călin, M., Butoi, E. D., Manea, S., Simionescu, M., & Manea, A. (2016) · Springer eBooks · doi:10.1007/978-3-319-34193-4_17 · Cited by 2
Possible Pivotal Role of Latent Chronic T. gondii Infection in the Pathogenesis of Atherosclerosis
PRANDOTA, J. (2017) · Journal of Cardiology and Therapy · doi:10.17554/j.issn.2309-6861.2017.04.130 · Cited by 2
Firth, C. A. (2006) · UC Research Repository (University of Canterbury) · doi:10.26021/6713 · Cited by 2
Spatial localisation of oxidative and inflammatory markers within advanced atherosclerotic plaques
Crone, E. M. (2008) · UC Research Repository (University of Canterbury) · doi:10.26021/6121 · Cited by 2
Gáll, T., Balla, J. G., Pethő, D., Balla, G., & Balla, J. (2026) · Antioxidants and Redox Signaling · doi:10.1177/15230864261443852 · Cited by 1
Nahal, A., Yaghmaei, B. G., & Maleki, F. A. (2009) · journal of ilam university of medical sciences · Cited by 1
Abdelhalim, M. A. K., Moussa, S. A. A., AL-Mohy, Y. H., Mohammad, A.-I., & Saud, I. (2013) · Cited by 1
6. Dysregulation of Iron Metabolism in Patients Undergoing Chronic Hemodialysis.
Kuragano, T., & Nakanishi, T. (2010) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.99.1226 · Cited by 1
(2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.10.295 · Cited by 1
The role of peripheral blood mononuclear cells in atherogenesis
Bispo, C. (2011) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · Cited by 1
Oxidized Low Density Lipoprotein Cytotoxicity and Vascular Disease
Gieseg, S. P., Crone, E. M., & Amit, Z. (2009) · Wiley eBooks · doi:10.1002/9783527628100.ch25 · Cited by 1
Filleria, S. F. G. (2019) · El Servicio de Difusión de la Creación Intelectual (National University of La Plata) · doi:10.35537/10915/78721 · Cited by 2
Role of ferroptosis in the occurrence and progression of acute ischemic strokePreprint
Li, H., Bi, M., Cheng, Z., He, M., & Li, W. (2023) · doi:10.22541/au.168620859.98713520/v1 · Cited by 1
Iron modulates phagocyte-endothelial cell interactions: Implications for atherosclerosis
Kartikasari, A. E. R. (2006) · Utrecht University Repository (Utrecht University)
IRON HOMEOSTASIS IN IMMUNE MONONUCLEAR CELLS: A POTENTIAL ROLE IN ATHEROGENESIS
Marques, L. (2015) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.13140/rg.2.2.24210.40643
Antioxidants and Chronic Vascular Disease: Animal Studies
Cyprus, T., & Praticò, D. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-387-29553-4_9
Plasma iron, zinc, and copper levels in heart disease patients in Dr. Sardjito Hospital Yogyakarta
Hastuti, P., Asdie, L. E. H., & Sofro, T. H. A. (2015) · Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Tinkov, A. A., & Nikonorov, A. А. (2013) · Biologia · doi:10.2478/s11756-013-0213-3
Amit, Z. (2008) · UC Research Repository (University of Canterbury) · doi:10.26021/6317
Wick, M. C., Chemelli-Steingruber, I. E., & Kremser, C. (2012)
Ferritin: A risk factor in ischemic heart disease?
López, E. N. F., de la Torre, D. L. A., García-Padilla, E., & Nolasco, R. (2015) · Medicina Interna de México
Badr, S. Q., & Abbas, B. A. (2017) · Journals & Books Hosting (International Knowledge Sharing Platform)
Lysosomal oxidation of Low Density Lipoproteins
Ahmad, F. (2017) · CentAUR (University of Reading)
Thukkani, A. K., & Jaffer, F. A. (2015) · Atherosclerosis · doi:10.1002/9781118828533.ch39
Saad-El-Din, A. A., Mazhar, A., & Khalil, W. A. (2020) · Journal of Radiation Research and Applied Sciences · doi:10.1080/16878507.2020.1756186
Tsuji, Y., Suzuki, N., Hitomi, Y., Mizuno‐Matsumoto, Y., Tokoro, T., & Nishimura, M. (2020) · International Journal of Biomedical Engineering and Clinical Science · doi:10.11648/j.ijbecs.20200602.14
Are Hemochromatosis Mutations Protective Against Iron-Mediated Atherogenesis?
Jerome, L. (2012) · InTech eBooks · doi:10.5772/26199
Alves, A. S. P. (2014) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/jfza-8483
(2007) · Elsevier eBooks · doi:10.1016/b978-012373657-4/50008-8
Kuo, K., Hung, S., Lin, Y., Tang, C.-F., Lee, T., Lin, C., & Tarng, D. (2013) · PLoS ONE · doi:10.1371/annotation/828aa889-2cb2-4bff-91d3-e247d7da2e14
Identification and immuno-infiltration analysis of cuproptosis regulators in human atherosclerosisPreprint
Ming, S., Wen, H., Zeng, C., Li, Z., Wang, C., Yan, S., & Liu, H. (2023) · Research Square · doi:10.21203/rs.3.rs-3039675/v1
Experimental Biology and Medicine Conference Thematic Issue
(2025) · Frontiers Media SA eBooks · doi:10.3389/978-2-8325-7005-0
Metadata
- Authors
- Stadler, N., Lindner, R. A., & Davies, M. J.
- Affiliations
- The Heart Research Institute (AU)
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2004-05
- Volume
- 24
- Issue
- 5
- Pages
- 949-954
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2158913228
- Cited by
- 310
- References
- 51
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 14 · 2023: 11 · 2022: 12 · 2021: 13 · 2020: 13 · 2019: 11 · 2018: 8 · 2017: 10 · 2016: 13 · 2015: 13 · 2014: 13 · 2013: 23 · 2012: 16
- FWCI
- 14.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Funders
- Medical Research Council
- Australian Research Council
- National Health and Medical Research Council
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Keywords
- atherosclerosis, transition metal ions, iron accumulation, copper, carotid plaque, cholesterol, human arteries
- MeSH terms
- Aged, Aged, 80 and over, Aorta, Coronary Artery Bypass, Carotid Arteries, Carotid Artery Diseases, Cholesterol, Copper, Electron Spin Resonance Spectroscopy, Female, Humans, Iron, Male, Mammary Arteries, Middle Aged, Mass Spectrometry, Endarterectomy, Carotid, Radial Artery, Tunica Intima
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