Nutraceuticals in immunosenescence

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

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Development and Validation of an Improved Oxygen Radical Absorbance Capacity Assay Using Fluorescein as the Fluorescent Probe

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Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

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Human nutrition, the gut microbiome and the immune system

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Prebiotic effects: metabolic and health benefits

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Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

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Transcriptional paradigms in mammalian mitochondrial biogenesis and function

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Activation of microglial cells by β-amyloid protein and interferon-γ

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Age-Associated Increased Interleukin-6 Gene Expression, Late-Life Diseases, and Frailty

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Cellular Antioxidant Activity (CAA) Assay for Assessing Antioxidants, Foods, and Dietary Supplements

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Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut

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Dietary polyphenols and their biological significance

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Regulation of cellular iron metabolism

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The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities

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Nutraceutical-definition and introduction

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Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

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Dendritic cells in intestinal immune regulation

Coombes, J. L., & Powrie, F. M. (2008) · Nature reviews. Immunology · doi:10.1038/nri2335 · Cited by 792 · see citing works

Telomere Diseases

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Oral (n-3) Fatty Acid Supplementation Suppresses Cytokine Production and Lymphocyte Proliferation: Comparison between Young and Older Women

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TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

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Innate immunosenescence: Effect of aging on cells and receptors of the innate immune system in humans

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Thymic involution and immune reconstitution.

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Does diet or alcohol explain the French paradox?

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Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function.

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Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019

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Free radicals and phagocytic cells

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Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers

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Probiotics and immune health

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Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway

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CD28 extinction in human T cells: altered functions and the program of T‐cell senescence

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NK-dependent DC maturation is mediated by TNFα and IFNγ released upon engagement of the NKp30 triggering receptor

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Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: A comparison of young and older men

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Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation

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Krüppel-like transcription factors: A functional family

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Mitochondrial biogenesis and healthy aging

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Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment.

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Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) and Sirtuin 1 (SIRT1) Reside in Mitochondria

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Inflammaging as a Major Characteristic of Old People: Can It Be Prevented or Cured?

Franceschi, C. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00358.x · Cited by 342 · see citing works

The immune system and the impact of zinc during aging

Haase, H., & Rink, L. (2009) · Immunity & Ageing · doi:10.1186/1742-4933-6-9 · Cited by 334 · see citing works

The impact of ageing on natural killer cell function and potential consequences for health in older adults

Hazeldine, J., & Lord, J. M. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2013.04.003 · Cited by 312 · see citing works

Prebiotics and synbiotics: towards the next generation

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Direct Detection and Quantification of Transition Metal Ions in Human Atherosclerotic Plaques: Evidence for the Presence of Elevated Levels of Iron and Copper

Stadler, N., Lindner, R. A., & Davies, M. J. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000124892.90999.cb · Cited by 310 · see citing works

The effect of iron deficiency anemia on the function of the immune system.

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Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes

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Effects of Fat and Fatty Acid Intake on Inflammatory and Immune Responses: A Critical Review

Galli, C., & Calder, P. C. (2009) · Annals of Nutrition and Metabolism · doi:10.1159/000228999 · Cited by 297 · see citing works

Resolvins and protectins: mediating solutions to inflammation

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The immune system as a physiological indicator of marginal copper status?

Bonham, M. P., O’Connor, J. M., HANNIGAN, B. M., & Strain, J. J. (2002) · British Journal Of Nutrition · doi:10.1079/bjn2002558 · Cited by 290 · see citing works

Impact of Trace Elements and Vitamin Supplementation on Immunity and Infections in Institutionalized Elderly Patients

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Dietary docosahexaenoic and eicosapentaenoic acid: Emerging mediators of inflammation

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Copper absorption and bioavailability

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Consumption of energy-dense, nutrient-poor foods by adult Americans: nutritional and health implications. The third National Health and Nutrition Examination Survey, 1988–1994

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Diagnosis of iron-deficiency anemia in the elderly

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Telomerase at the intersection of cancer and aging

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Differential immunomodulation with long-chainn-3 PUFA in health and chronic disease

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The Th17/Treg balance is disturbed during aging

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A probiotic fermented dairy drink improves antibody response to influenza vaccination in the elderly in two randomised controlled trials

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Effects of oligosaccharide on the faecal flora and non-specific immune system in elderly people

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P38 Mitogen Activated Protein Kinase Regulates Endothelial VCAM-1 Expression at the Post-transcriptional Level

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Microbiological Effects of Consuming a Synbiotic Containing Bifidobacterium bifidum, Bifidobacterium lactis, and Oligofructose in Elderly Persons, Determined by Real-Time Polymerase Chain Reaction and Counting of Viable Bacteria

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Polyunsaturated fatty acids, membrane organization, T cells, and antigen presentation

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Phenotypic and Functional Analysis of CD4+CD25−Foxp3+ T Cells in Patients with Systemic Lupus Erythematosus

Bonelli, M. M., Savitskaya, A., Steiner, C.-W., Rath, E., Smolen, J. S., & Scheinecker, C. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.3.1689 · Cited by 191 · see citing works

Parental Dietary Fat Intake Alters Offspring Microbiome and Immunity

Myles, I. A., Fontecilla, N. M., Janelsins, B., Vithayathil, P. J., Segre, J. A., & Datta, S. K. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301057 · Cited by 174 · see citing works

Protective effects of microglia in multiple sclerosis

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Ageing is associated with diminished apoptotic cell clearancein vivo

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B cell maintenance and function in aging

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Zinc and immunoresistance to infection in aging: new biological tools

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Effects of aging on B cell function

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Mobilization of liver iron by ferroxidase (ceruloplasmin).

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Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential

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Effects of one year of supplementation with zinc and other micronutrients on cellular immunity in the elderly.

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Macrophage Deletion of p38α Partially Impairs Lipopolysaccharide-Induced Cellular Activation

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Differences in Composition and Mucosal Adhesion of Bifidobacteria Isolated from Healthy Adults and Healthy Seniors

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The Risks of Copper Toxicity Contributing to Cognitive Decline in the Aging Population and to Alzheimer's Disease

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The ageing B cell population: Composition and function

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(n-3) Fatty Acids and Infectious Disease Resistance

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Revisiting Rates of Reactivation Tuberculosis: A Population-based Approach

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Historic perspective: Prebiotics, probiotics, and other alternatives to antibiotics ,

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Low Grade Inflammation as a Common Pathogenetic Denominator in Age-Related Diseases: Novel Drug Targets for Anti-Ageing Strategies and Successful Ageing Achievement

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Regulatory activity of polyunsaturated fatty acids in T-cell signaling

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Fish oil decreases natural resistance of mice to infection with Salmonella typhimurium

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The interaction between gut microbiota and age-related changes in immune function and inflammation

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Methods of assessment of copper status in humans: a systematic review

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Phagocyte dysfunction, tissue aging and degeneration

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Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply

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Zinc and immunocompetence in elderly people: effects of zinc supplementation for 3 months

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Dietary Fish Oil Reduces Survival and Impairs Bacterial Clearance in C3H/Hen Mice Challenged with Listeria Monocytogenes

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Immune dysfunction in rats fed a diet deficient in copper

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Zinc, T-cell pathways, aging: role of metallothioneins

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Effects of Antioxidant Polyphenols on TNF-Alpha-Related Diseases

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The Interplay between the Gut Immune System and Microbiota in Health and Disease: Nutraceutical Intervention for Restoring Intestinal Homeostasis

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The Impact of Aging on Regulatory T-Cells

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β-Carotene and selenium supplementation enhances immune response in aged humans

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Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases

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Fish Oil-Fed Mice Have Impaired Resistance to Influenza Infection ,

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The frequency of regulatory CD3+CD8+CD28−CD25+ T lymphocytes in human peripheral blood increases with age

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