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Cited by 795

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Myeloperoxidase and Cardiovascular Disease

Nicholls, Stephen J., Hazen, Stanley L.·2005·Arteriosclerosis, Thrombosis, and Vascular Biology

Abstract

Myeloperoxidase (MPO) is a leukocyte-derived enzyme that catalyzes the formation of a number of reactive oxidant species. In addition to being an integral component of the innate immune response, evidence has emerged that MPO-derived oxidants contribute to tissue damage during inflammation. MPO-catalyzed reactions have been attributed to potentially proatherogenic biological activities throughout the evolution of cardiovascular disease, including during initiation, propagation, and acute complication phases of the atherosclerotic process. As a result, MPO and its downstream inflammatory pathways represent attractive targets for both prognostication and therapeutic intervention in the prophylaxis of atherosclerotic cardiovascular disease.

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Crossref · 10.1161/01.atv.0000163262.83456.6d

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Metadata

Authors
Nicholls, S. J., & Hazen, S. L.
Venue
Arteriosclerosis, Thrombosis, and Vascular Biology
Published
2005-06
Volume
25
Issue
6
Pages
1102-1111
ISSN
  • 1079-5642 (ISSN-L)
  • 1524-4636
OpenAlex
W2109539718
Cited by
795
References
16
FWCI
10.41
Type
journal article
Language
en
Open access
closed

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This page
CoChat. (2026). Citation check: Myeloperoxidase and Cardiovascular Disease. https://app.cochat.ai/papers/10.1161/01.atv.0000163262.83456.6d
The paper
Nicholls, S. J., & Hazen, S. L. (2005). Myeloperoxidase and Cardiovascular Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.0000163262.83456.6d

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.