Chronic Management of Blood Pressure After Stroke

Pedelty, Laura; Gorelick, Philip B.

doi:10.1161/01.hyp.0000129170.50448.5f

Cited by 122Blood Pressure and Hypertension StudiesAcute Ischemic Stroke ManagementIntracerebral and Subarachnoid Hemorrhage Research

Chronic Management of Blood Pressure After Stroke

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Pedelty, Laura, Gorelick, Philip B.·2004·Hypertension

DOI 10.1161/01.hyp.0000129170.50448.5f

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Abstract

A 70-year-old, right-handed African American woman with diabetes mellitus, treated with an oral hypoglycemic, and untreated mild hypertension developed right-sided face, arm, and leg weakness while at home preparing breakfast.She was able to reach the telephone and dial 911.An ambulance was summoned, and the Emergency Medical Service team, on arrival, noted a right facial droop, dysarthria, and right-sided weakness.She was transported to a local hospital, arriving within an hour of the onset of the event.The hospital stroke team was consulted and initiated an evaluation.

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Although an effect of medications in the two hypertensive groups cannot be completely excluded, they could not have entirely caused the excessive sympathetic hyperactivity.
“Therefore, although we cannot completely exclude an effect of medications in our 2 hypertensive groups, they could not have entirely caused the excessive sympathetic hyperactivity.”
From Sympathetic Neural Activation in Nondiabetic Metabolic Syndrome and Its Further Augmentation by Hypertension (2004) · cites this paper as [25]
β-blockers may have no effect or decrease MSNA in hypertensive patients.
“Although we cannot entirely exclude some influence of these agents, it is known in hypertensive patients that chronic ACE inhibitor therapy does not affect MSNA levels, 22 ARBs may decrease it, 23 and ␤-blockers may have no effect or decrease MSNA.24,25”
From Sympathetic Neural Activation in Nondiabetic Metabolic Syndrome and Its Further Augmentation by Hypertension (2004) · cites this paper as [25]

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Authors: Pedelty, L., & Gorelick, P. B.
Affiliations: University of Illinois Chicago (US)
ORCID: Gorelick, Philip B.
Venue: Hypertension
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-07
Volume: 44
Issue: 1
Pages: 1-5
ISSN: 0194-911X (ISSN-L)
1524-4563
DOI: 10.1161/01.hyp.0000129170.50448.5f
OpenAlex: W2096942434
Cited by: 122
References: 50
Citations by year: 2025: 1 · 2022: 1 · 2021: 2 · 2017: 3 · 2015: 5 · 2014: 5 · 2013: 2 · 2012: 5
FWCI: 14.19
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Hypertension (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (R01 NS)
National Institute of Neurological Disorders and Stroke (R01 NS33430, R01NS033430)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
Health Sciences › Medicine › Neurology › Intracerebral and Subarachnoid Hemorrhage Research
Keywords: blood pressure control, stroke, diabetes mellitus, acute stroke, stroke rehabilitation, secondary stroke prevention, African American women
MeSH terms: Aged, Antihypertensive Agents, Blood Pressure, Dementia, Female, Humans, Hypertension, Recurrence, Risk, Stroke, Diabetes Complications

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Chronic Management of Blood Pressure After Stroke

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