Cited by 32Cardiac Arrest and ResuscitationAcute Myocardial Infarction ResearchCardiac Ischemia and Reperfusion

Science of self-preservation: how melanocortin action in the brain modulates body weight, blood pressure, and ischemic damage

Open access
Corander, Marcus P., Fenech, Matthew, Coll, Anthony P.·2009·Circulation

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Integrity signals

Registry

Crossref · 10.1161/circulationaha.109.854612

Cites

73 of 73 references verified0 citation errors · 0 not checkable

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  • The melanocortin system also plays an important role in regulating sympathetic nervous system activity and blood pressure besides its effects on food intake and body weight regulation.

    “Besides its effects on food intake and body weight regulation, the melanocortin system also plays an important role in regulating SNS activity and BP.”
  • Melanocortins play an important role in regulating blood pressure and sympathetic nervous system activity as well as energy balance, glucose and other metabolic functions in humans and experimental animals.

    “Melanocortins play an important role in regulating blood pressure (BP) and sympathetic nervous system (SNS) activity as well as energy balance, glucose and other metabolic functions in humans and experimental animals.”
  • Administration of melanocortin peptides prevented oxygen release of free radicals in a model of myocardial ischemia/reperfusion.

    “Administration of melanocortin peptides prevented oxygen release of free radicals, inflammatory responses, development of severe ventricular arrhythmia, and increased survival in a model of myocardial ischemia/reperfusion [2, 67].”
  • Administration of melanocortin peptides prevented inflammatory responses in a model of myocardial ischemia/reperfusion.

    “Administration of melanocortin peptides prevented oxygen release of free radicals, inflammatory responses, development of severe ventricular arrhythmia, and increased survival in a model of myocardial ischemia/reperfusion [2, 67].”
  • Administration of melanocortin peptides increased survival in a model of myocardial ischemia/reperfusion.

    “Administration of melanocortin peptides prevented oxygen release of free radicals, inflammatory responses, development of severe ventricular arrhythmia, and increased survival in a model of myocardial ischemia/reperfusion [2, 67].”

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2 retracted

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Authors
Corander, M. P., Fenech, M., & Coll, A. P.
Affiliations
University of Cambridge (GB)
Venue
Circulation
Published
2009-12
Volume
120
Issue
22
Pages
2260-2268
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2115860315
Cited by
31
References
72
Citations by year
2024: 1 · 2022: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 4 · 2012: 3
FWCI
4.91
Type
journal article
Language
en
Open access
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • UEA Digital Repository (University of East Anglia) (submittedVersion)
Funders
  • Wellcome Trust (08478/Z/08/Z, 084748, 73637)
  • Medical Research Council (G108/617)
Topics
  • Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Cardiac Ischemia and Reperfusion
Keywords
self-preservation, self-preservation instinct, survival instinct
MeSH terms
Blood Pressure, Body Weight, Brain, Humans, Hypertension, Obesity, Reperfusion Injury, Receptors, Melanocortin, Melanocortins

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