The DOI matches its Crossref record, with a small difference in title or year; 46 of the 46 references it cites were found in a registry or an index.
Healthy Lifestyle Through Young Adulthood and the Presence of Low Cardiovascular Disease Risk Profile in Middle Age: The Coronary Artery Risk Development in (Young) Adults (CARDIA) Study
Open accessAbstract
Background—: A low cardiovascular disease risk profile (untreated cholesterol <200 mg/dL, untreated blood pressure <120/<80 mm Hg, never smoking, and no history of diabetes mellitus or myocardial infarction) in middle age is associated with markedly better health outcomes in older age, but few middle-aged adults have this low risk profile. We examined whether adopting a healthy lifestyle throughout young adulthood is associated with the presence of the low cardiovascular disease risk profile in middle age. Methods and Results—: The Coronary Artery Risk Development in (Young) Adults (CARDIA) study sample consisted of 3154 black and white participants 18 to 30 years of age at year 0 (1985–1986) who attended the year 0, 7, and 20 examinations. Healthy lifestyle factors defined at years 0, 7, and 20 included average body mass index <25 kg/m 2 , no or moderate alcohol intake, higher healthy diet score, higher physical activity score, and never smoking. Mean age (25 years) and percentage of women (56%) were comparable across groups defined by number of healthy lifestyle factors. The age-, sex-, and race-adjusted prevalences of low cardiovascular disease risk profile at year 20 were 3.0%, 14.6%, 29.5%, 39.2%, and 60.7% for people with 0 or 1, 2, 3, 4, and 5 healthy lifestyle factors, respectively ( P for trend <0.0001). Similar graded relationships were observed for each sex-race group (all P for trend <0.0001). Conclusions—: Maintaining a healthy lifestyle throughout young adulthood is strongly associated with a low cardiovascular disease risk profile in middle age. Public health and individual efforts are needed to improve the adoption and maintenance of healthy lifestyles in young adults.
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In the citing paper
“Prevention is effective in reducing the impact of CVD”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [3]
In the citing paper
“the elimination of health risk behaviours would make it possible to prevent at least 80% of CVD and even 40% of cancers”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [3]
In the citing paper
“the elimination of health risk behaviours would make it possible to prevent at least 80% of CVD and even 40% of cancers, thus providing added value for other chronic diseases.3,4”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [3]
In the citing paper
“Findings from the Coronary Artery Risk Development in Young Adults (CARDIA) study demonstrate that young adults aged 18 to 30 years with healthy behaviors grow up to become older adults with lower biological risk.12”
From Better Population Health Through Behavior Change in Adults: A Call to Action (2013) · cites this paper as [12]
In the citing paper
“Moreover, highlighting the promise of behavior change, those who did not have a healthy lifestyle at baseline but began to practice healthy behaviors later still had higher rates of ideal cardiovascular biomarkers than those who never adopted healthy behaviors.”
From Better Population Health Through Behavior Change in Adults: A Call to Action (2013) · cites this paper as [12]
In the citing paper
“These results indicate that regardless of timing, the adoption of a healthy lifestyle has value for cardiovascular health.12”
From Better Population Health Through Behavior Change in Adults: A Call to Action (2013) · cites this paper as [12]
In the citing paper
“Among those who practiced all of 5 healthy lifestyle behaviors in young adulthood (nonsmoking, low or no alcohol use, healthy diet, physically active, maintenance of normal weight), 60% had all ideal cardiovascular biomarkers in middle age.”
From Better Population Health Through Behavior Change in Adults: A Call to Action (2013) · cites this paper as [12]
In the citing paper
“In contrast, of those who practiced none of these healthy behaviors in young adulthood, fewer than 5% reached middle age with all cardiovascular biomarkers at ideal levels.12”
From Better Population Health Through Behavior Change in Adults: A Call to Action (2013) · cites this paper as [12]
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Cites
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423
Lloyd-Jones, D. M., Hong, Y., Labarthe, D., Mozaffarian, D., Appel, L. J., Van Horn, L., Greenlund, K., Daniels, S., Nichol, G., Tomaselli, G. F., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192703 · Cited by 4,750
Self-citationDiet, lifestyle, and the risk of type 2 diabetes mellitus in women.
Hu, F. B., Manson, J. E., Stampfer, M. J., Colditz, G., Liu, S., Solomon, C. G., & Willett, W. C. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010492 · Cited by 2,901
Lichtenstein, A. H., Appel, L. J., Brands, M., Carnethon, M., Daniels, S., Franch, H. A., Franklin, B., Kris-Etherton, P., Harris, W. S., Howard, B., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176158 · Cited by 2,705
Warnick, G. R., Benderson, J., & Albers, J. J. (1982) · Clinical Chemistry · doi:10.1093/clinchem/28.6.1379 · Cited by 2,154
A multivariate technique for multiply imputing missing values using a sequence of regression models
Raghunathan, T. E., Lepkowski, J. M., Hoewyk, J. V., & Solenberger, P. W. (2001) · Survey methodology · Cited by 1,981
Kushi, L. H., Byers, T., Doyle, C., Bandera, E. V., McCullough, M., Gansler, T., Andrews, K. S., Thun, M. J., & The American Cancer Society 2006 Nutrition and Physical Activity Guidelines Advisory Committee (2006) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.56.5.254 · Cited by 1,901
Primary Prevention of Coronary Heart Disease in Women through Diet and Lifestyle
Stampfer, M. J., Hu, F. B., Manson, J. E., Rimm, E. B., & Willett, W. C. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007063430103 · Cited by 1,794
Cardia: study design, recruitment, and some characteristics of the examined subjects
FRIEDMAN, G. D., Cutter, G., Donahue, R. P., Hughes, G. H., Hulley, S. B., Jacobs, D. R., Liu, K., & Savage, P. J. (1988) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(88)90080-7 · Cited by 1,689
Self-citationPrediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age
Lloyd-Jones, D. M., Leip, E. P., Larson, M. G., D’Agostino, R. B., Beiser, A., Wilson, P. W. F., Wolf, P. A., & Levy, D. (2006) · Circulation · doi:10.1161/circulationaha.105.548206 · Cited by 1,298
Self-citationLifetime risks of cardiovascular disease
Berry, J. D., Dyer, A., Cai, X., Garside, D. B., Ning, H., Thomas, A., Greenland, P., Van Horn, L., Tracy, R. P., & Lloyd-Jones, D. M. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1012848 · Cited by 945
Self-citationStamler, J., Stamler, R., Neaton, J. D., Wentworth, D. N., Daviglus, M. L., Garside, D., Dyer, A. R., Liu, K., & Greenland, P. (1999) · JAMA · doi:10.1001/jama.282.21.2012 · Cited by 723
Self-citationFolsom, A. R., Yatsuya, H., Nettleton, J. A., Lutsey, P. L., Cushman, M., & Rosamond, W. D. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.11.041 · Cited by 713
Alberg, A. J., Ford, J. G., & Samet, J. M. (2007) · CHEST Journal · doi:10.1378/chest.07-1347 · Cited by 634
Coronary Heart Disease Mortality Among Young Adults in the U.S. From 1980 Through 2002
Ford, E. S., & Capewell, S. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.05.056 · Cited by 589
Shiroma, E. J., & Lee, I.-M. (2010) · Circulation · doi:10.1161/circulationaha.109.914721 · Cited by 578
Validity and Reliability of Short Physical Activity History
Jacobs, D. R., Hahn, L. P., Haskell, W. L., Pirie, P. L., & Sidney, S. (1989) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-198911000-00003 · Cited by 533
Aging, Health Risks, and Cumulative Disability
Harper, D. W., & Forbes, W. F. (1998) · New England Journal of Medicine · doi:10.1056/nejm199808133390716 · Cited by 515
Effect of BMI on Lifetime Risk for Diabetes in the U.S.
Narayan, K. M. V., Boyle, J. P., Thompson, T. J., Gregg, E. W., & Williamson, D. F. (2007) · Diabetes Care · doi:10.2337/dc06-2544 · Cited by 510
Moderate Alcohol Consumption During Adult Life, Drinking Patterns, and Breast Cancer Risk
Chen, W. Y., Rosner, B., Hankinson, S. E., Colditz, G. A., & Willett, W. C. (2011) · JAMA · doi:10.1001/jama.2011.1590 · Cited by 509
Primary Prevention of Stroke by Healthy Lifestyle
Chiuve, S. E., Rexrode, K. M., Spiegelman, D. L., Logroscino, G., Manson, J. E., & Rimm, E. B. (2008) · Circulation · doi:10.1161/circulationaha.108.781062 · Cited by 508
Aging, Health Risks, and Cumulative Disability
Vita, A. J., Terry, R. B., Hubert, H. B., & Fries, J. F. (1998) · New England Journal of Medicine · doi:10.1056/nejm199804093381506 · Cited by 499
Enzymatic methods for quantification of lipoprotein lipids
Warnick, G. R. (1986) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(86)29064-3 · Cited by 393
Mozaffarian, D., Kamineni, A., Carnethon, M., Djoussé, L., Mukamal, K. J., & Siscovick, D. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.21 · Cited by 358
Alcohol Consumption and the Risk of Hypertension in Women and Men
Sesso, H. D., Cook, N. R., Buring, J. E., Manson, J. E., & Gaziano, J. M. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.104968 · Cited by 353
The CARDIA dietary history: Development, implementation, and evaluation
McDonald, A., Horn, L. V., Slattery, M. L., Hilner, J. E., Bragg, C., Caan, B. J., Jacobs, D. R., Liu, K., Hubert, H. B., Gernhofer, N., et al. (1991) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(21)01299-2 · Cited by 288
Self-citationCigarette smoking: An undertreated risk factor for cardiovascular disease
Erhardt, L. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.01.007 · Cited by 284
Wagenknecht, L. E., Cutter, G., Haley, N. J., Sidney, S. S., Manolio, T. A., Hughes, G. H., & Jacobs, D. R. (1990) · American Journal of Public Health · doi:10.2105/ajph.80.9.1053 · Cited by 278
Evaluating adherence to recommended diets in adults: the Alternate Healthy Eating Index
McCullough, M. L., & Willett, W. C. (2006) · Public Health Nutrition · doi:10.1079/phn2005938 · Cited by 267
A study of the reliability and comparative validity of the cardia dietary history.
Liu, K., Slattery, M. L., Jacobs, D. R., Cutter, G., McDonald, A., Horn, L. V., Hilner, J. E., Caan, B. J., Bragg, C., & Dyer, A. R. (1994) · PubMed · Cited by 264
Self-citationAlcohol Consumption and Cardiovascular Mortality Among U.S. Adults, 1987 to 2002
Mukamal, K. J., Chen, C. M., Rao, S. R., & Breslow, R. A. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.10.056 · Cited by 245
Coronary heart disease prevention: Nutrients, foods, and dietary patterns
Bhupathiraju, S. N., & Tucker, K. L. (2011) · Clinica Chimica Acta · doi:10.1016/j.cca.2011.04.038 · Cited by 231
Capewell, S., Ford, E. S., Croft, J. B., Critchley, J. A., Greenlund, K. J., & Labarthe, D. R. (2010) · Bulletin of the World Health Organization · doi:10.2471/blt.08.057885 · Cited by 200
Yu, S., Yarnell, J. W. G., Sweetnam, P. M., & Murray, L. (2003) · Heart · doi:10.1136/heart.89.5.502 · Cited by 179
Alcohol intake and blood pressure in young adults: The CARDIA study
Dyer, A. R., Cutter, G., Liu, K., Armstrong, M. A., FRIEDMAN, G. D., Hughes, G. H., Dolce, J. J., Raczynski, J. M., Burke, G. L., & Manolio, T. A. (1990) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(90)90050-y · Cited by 161
Self-citationDaviglus, M. L., Liu, K., Greenland, P., Dyer, A. R., Garside, D. B., Manheim, L. M., Lowe, L. P., Rodin, M. B., Lubitz, J. D., & Stamler, J. (1998) · New England Journal of Medicine · doi:10.1056/nejm199810153391606 · Cited by 160
Self-citationLloyd‐Jones, D. M., Dyer, A. R., Wang, R., Daviglus, M. L., & Greenland, P. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.09.099 · Cited by 146
Self-citationParker, E. D., Schmitz, K. H., Jacobs, D. R., Dengel, D. R., & Schreiner, P. J. (2007) · American Journal of Public Health · doi:10.2105/ajph.2004.055889 · Cited by 144
Position Stand of the American College of Sports Medicine
Pollock, M. L., & Froelicher, V. F. (1990) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-199007000-00001 · Cited by 140
Favorable Cardiovascular Risk Profile in Middle Age and Health-Related Quality of Life in Older Age
Daviglus, M. L., Liu, K., Pirzada, A., Yan, L. L., Garside, D. B., Feinglass, J. M., Guralnik, J. M., Greenland, P., & Stamler, J. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.20.2460 · Cited by 123
Self-citationFord, E. S., Li, C., Zhao, G., Pearson, W. S., & Capewell, S. (2009) · Circulation · doi:10.1161/circulationaha.108.835728 · Cited by 106
Cardiovascular Risk Profile Earlier in Life and Medicare Costs in the Last Year of Life
Daviglus, M. L. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.9.1028 · Cited by 73
Self-citationLight-to-moderate alcohol consumption and risk of sudden cardiac death in women
Chiuve, S. E., Rimm, E. B., Mukamal, K. J., Rexrode, K. M., Stampfer, M. J., Manson, J. E., & Albert, C. M. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.05.035 · Cited by 62
Cardiorespiratory fitness and coronary artery calcification in young adults: The CARDIA Study
Lee, C.-D., Jacobs, D. R., Hankinson, A. L., Iribarren, C., & Sidney, S. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.06.012 · Cited by 57
Hardoon, S. L., Morris, R. W., Thomas, M. C., Wannamethee, S. G., LENNON, L. T., & Whincup, P. H. (2010) · Diabetes Care · doi:10.2337/dc09-2295 · Cited by 36
Flagged first, then by citations
Research works printed but not linked: 1
- National Heart Lung and Blood Institute. Morbidity & Mortality: 2009 Chart Book on Cardiovascular, Lung, and Blood Diseases. Bethesda, MD: National Institutes of Health; 2009.
Cited by
Sorted by citations
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw106 · Cited by 6,457
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162
Lloyd-Jones, D. M., Allen, N. B., Anderson, C. A. M., Black, T., Brewer, L. C., Foraker, R. E., Grandner, M. A., Lavretsky, H., Perak, A. M., Sharma, G., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001078 · Cited by 2,785
Self-citation2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.018 · Cited by 1,582
“Prevention is effective in reducing the impact of CVD; the elimination of health risk behaviours would make it possible to prevent at least 80% of CVD and even 40% of cancers, thus providing added value for other chronic diseases.(3,4)”
Background
Metadata
- Authors
- Liu, K., Daviglus, M. L., Loria, C. M., Colangelo, L. A., Spring, B., Moller, A. C., & Lloyd-Jones, D. M.
- Affiliations
- Northwestern University (US)
- From the Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L., M.L.D., L.A.C., B.S., A.C.M., D.M.L.-J.), and National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD (C.M.L.).
- ORCID
- Venue
- Circulation
- Published
- 2012-02-28
- Volume
- 125
- Issue
- 8
- Pages
- 996-1004
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC3353808
- OpenAlex
- W2114377026
- Cited by
- 371
- References
- 46
- Citations by year
- 2026: 18 · 2025: 18 · 2024: 24 · 2023: 30 · 2022: 28 · 2021: 46 · 2020: 28 · 2019: 23 · 2018: 30 · 2017: 22 · 2016: 26 · 2015: 22 · 2014: 18 · 2013: 23 · 2012: 14
- FWCI
- 15.85
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (n01hc95095-66-0-1, n01hc48047-55-0-1, n01hc48049-61-0-1)
- National Heart, Lung, and Blood Institute (N01 HC 95095, N01-HC-048049, N01 HC095095, N01 HC048047, N01-HC-480-47)
- National Center for Research Resources (UL1RR025741)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Lifestyle Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- healthy lifestyle, early adulthood, middle age (human life stage), body mass index, alcohol consumption, healthy eating, physical activity, never smoking, untreated hypertension, CARDIA study, sex differences, racial differences
- MeSH terms
- Adult, Age Factors, Cardiovascular Diseases, Coronary Artery Disease, Female, Humans, Life Style, Longitudinal Studies, Male, Middle Aged, Risk Factors, Cohort Studies, Young Adult
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